Desmoid
Tumors Market Top Key Players
Some of
key the players in the market are Amgen Inc., Novartis AG, Abbott Laboratories,
Bayer AG, AbbVie Inc., Beckman Coulter Inc., Stryker Corporation, Debiopharm
Group, F. Hoffmann-La Roche Ltd, and others.
Market
Scenario
Desmoid
tumors are also known as desmoid fibromatosis. These benign growths occur very
rarely in the general population. Desmoid tumor usually develops in the fibrous
tissue of the body, commonly in the arms, legs or midsection, and sometimes in
the head and neck. The term desmoid was derived from the Greek word desmos,
which means tendonlike. Desmoid tumors appear as well-differentiated, and firm
overgrowths of fibrous tissue. According to the U.S National Library of
Medicine, Desmoid tumors are very rare as the rate of occurrence is estimated
to be 1 to 2 per 500,000 people worldwide. It is also stated that nearly 900 to
1,500 new cases are registered per year in the United States. Tumors associated
with familial adenomatous polyposis (FAP) are less common than sporadic desmoid
tumors.
On molecular level, desmoid tumor is characterized
by one of the two mutations in the gene i.e. mutations in the adenomatous
polyposis coli (APC) gene, or in the β-catenin gene, CTNNB1. During diagnostic
procedures CTNNB1 mutation is detected, especially, when pathological
differential diagnosis is difficult.
According
to the Desmoid Rare Foundation, individuals within the age group of 15 and 60
are more likely to get affected by this condition. It is also stated that the
condition is more prevalent in women than in men (2:1).
For the
diagnosis of desmoid tumor there are many non-invasive methods available to
detect desmoid tumor which include ultrasound, MRI scan, and CT scan. The
actual diagnosis of this tumor can be made only after examining a small piece
of the tumor by a trained pathologist.
The
symptoms of desmoid tumors include a painless swelling or lump, pain and
obstruction of the bowels, limping, pain caused by compressed nerves or
muscles, and others.
The most
commonly used treatment options for desmoid tumors are anti-inflammatory
medication, Chemotherapy, Hormone therapy, and surgery among others. Various
new therapies are under investigation such as Angiogenesis inhibitors, and
Chemotherapy agents. As mutations in the CTNNB1 gene is found to be most
commonly occurring in desmoid tumor. So, it is expected that very soon mutation
analysis be used to predict the risk of recurrence and to aid in designing
individual therapies.
Notably,
the market is expected to expand in the near future due to rising demand of
effective chemotherapeutic agents, high unmet needs of current treatment, and
increase in research and development expenditure.
Despite
these drivers, there are some issues associated with desmoid tumors market.
High cost of treatment & management of desmoid tumors and related disorders,
and lack of infrastructure in the middle and low income countries may hamper
the growth of the market.
It is
estimated that desmoid tumors market is expected to grow at a CAGR 4.5% during
the forecast period of 2017-2023.
Segmentation
The
desmoid tumors market is segmented on the basis of diagnosis, treatment, and
end-user.
On the
basis of diagnosis, market is segmented into biopsy, electron microscopic
examination, immunohistochemical analysis, others
On the
basis of treatment, market is classified into surgery, radiation therapy,
anti-inflammatory medication, hormone therapy, chemotherapy, novel
molecular-targeted therapy, others. Novel molecular-targeted therapy is further
segmented into gleevec based therapy, and sorafenib based therapy
On the
basis of end-user, market is segmented into hospital, clinics, and
others.
Table Of Contents:
Chapter 1. Report
Prologue
Chapter 2. Market
Introduction
2.1 Definition
2.2 Scope Of The Study
2.2.1 Research Objective
2.2.2 Assumptions
2.2.3 Limitations
Chapter 3. Research
Methodology
3.1 Introduction
3.2 Primary Research
3.3 Secondary Research
3.4 Market Size Estimation
Chapter 4. Market
Dynamics
4.1 Drivers
4.2 Restrains
4.3 Opportunities
4.4 Challenges
4.5 Macroeconomic Indicators
4.6 Technology Trends & Assessment
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