Wednesday, 10 April 2019

Nasal Drug Delivery Market 2019 Size, Share, Trends, Opportunities, Growth Factors, Key Players, And Regional Forecast 2023 Research Report

Market Scenario
Increasing popularity of over-the-counter nasal drugs such as inhalers for the common cold is also propel the market in an upward manner. Nasal drugs prove to be advantageous for the market, with a plethora of factors like good penetration of the drugs into the nasal cavity, improving patient compliance, rapid absorption, onset of action, and requirement of low dosage.
The nasal route administration is experiencing tremendous growth due to its noninvasive nature consequently reducing pain and threat of infections. It allows the patient to self-administer drugs thus not requiring any external help. The high vasculature, high permeability, and low enzymatic environment of nasal cavity are perfectly apt for systemic delivery of drug molecules via nose. There is no risk of drug destruction by hydrogen chloride (HCl) present in the stomach thereby increasing bioavailability which reduces the dosage of the drug. This, in turn, leads to proportional reduction in side effects.
Key Players
  • Novartis AG
  • Pfizer, Inc.
  • Sanofi-Aventis
  • Merck & Co., Inc.
  • AptarGroup Inc.
  • Johnson & Johnson Services, Inc.
  • GlaxoSmithKline plc
  • Becton Dickson & Company
Regional Analysis
UAE is the largest market for nasal drug delivery in entire Middle East and Africa nasal drug delivery Market closely followed by Egypt. The rest of Africa’s market is growing at a very fast rate due to huge unmet medical needs and growing popularity of nasal route.
Segmentation
Middle East and Africa nasal drug delivery market has been segmented on the basis of dosage form which comprises of drops, sprays, powder, gels and ointments. On the basis of system, market is segmented into unit dose, multi-dose and metered dose. On the basis of delivery technologies; market is segmented into spray, nebulizers and other. On the basis of therapeutic applications; market is segmented into rhinitis, congestion, vaccinations and others.
Drivers and Restraints
The market for nasal drug delivery is growing remarkably with a consistently good CAGR due to the benefits accompanying nasal drugs.  Other driving factors include innovation of drugs which are absorbed easily from the nasal route, innovations in advanced products which allow the delivery of precise doses and also ease of administration. However, the restraints that threaten the growth of the market are irritation of the nasal route and the low dose of the drug that can be delivered as compared to other routes of administration. Other constraints include concurrent low popularity of the route which reduces economies of scale in producing these delivery devices and low awareness. According to an extensive report by Market Research Future (MRFR), the Middle East and Africa nasal drug delivery market is presumed to reach around USD 1.59 billion in 2022 surging at a CAGR of 8.1% from 2017 to 2022. The market was estimated to be worth USD 1 billion in 2015.
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Intussusception Market 2019 Global Analysis, Growth, Size, Share, Trends, Forecast to 2023

Market Scenario
According to the National health statistics, intussusception affects about 1 in every 1,900 children in the US. Its incidence is more common in children between one to five months, peaking at four to nine months of age, and then gradually declines at around 18 months. Intussusception affects boys and girls, with a ratio of approximately 3:1.
Intussusception, also called bowel obstruction, is a potentially life-threatening condition caused by folding of one part of the intestine into another part, which causes a blockage in the intestine. The blockage hamper the excretion process. Intussusception is dominant in children of age 2 months-2 years. However, adults may also be affected by the intussusception. It commonly occurs where the small and large intestines meet. Additionally, it can occurs due to various causes such as tumors, inflammation, Meckel's diverticulum, duplication, appendix, hyperplasia of Peyer's patches, intestinal surgery, polyps, tumors, inflammation, etc.
It block the blood supply to intestine and causes tissue death. Tissue death can lead to infection, internal bleeding, tearing, damage to the intestines, and peritonitis. The primary symptoms of intussusception include acute abdominal pain, vomiting, nausea, lethargy, blood or mucus in the stools, constipation, etc. The risk factors for intussusception are age, sex, abnormal intestinal formation at birth, a family history, etc.
The developments in the surgery segment, such as minimal invasive laparoscopy surgery, is driving the global intussusception market. The drug segment is, however, suffering from market fragmentation, which has put pressure on the price margins. The loss of patents and the rise of counterfeited drugs has also restricted the market growth. The other market constrains are high cost of surgery and complications of the surgery. Market development represents the best strategy for the market growth. The market is expected to witness exponential growth over the review period owing to minimal invasive surgical procedures.
The global intussusception market is expected to reach USD 6.3 billion by 2023, and the market is projected to grow at a CAGR of ~ 4.4 % during the forecast period 2017-2023.
The market is growing at a very steady pace. Companies are opting various business strategies to capture a reasonable amount of share in the market. Product development represents the best strategy for dominating the market as surgery is the definitive treatment for intussusception market. The advent of minimally invasive treatment and diagnostic techniques such as computed tomography has changed the market landscape for to a large extent. Miniaturization of surgical instruments and development of minimal invasive treatment such as robotic laparoscopy is expected to drive the future market in the developed regions of North America and Europe. The cost of the product will be a decisive factor in the developing regions such as Asia Pacific and, especially, Africa. The growing demand for better minimally invasive surgical procedures is the greatest unmet need of the market.
Key Players in the Global Intussusception Market
Some of the key players profiled in the report are Pfizer, Inc., Janssen Pharmaceuticals, Inc., Abbott, GlaxoSmithKline plc, sanofi-aventis U.S. LLC. , Novartis AG, Bayer AG, FUJIFILM Holdings Corporation, General Electric Company, Shimadzu Corporation, Carestream Health, Bristol-Myers Squibb Company, and others.
Segments of Global Intussusception Market
The global intussusception market has been segmented on the basis of type, diagnosis, treatment, and end user.
Based on the type, the market has been segmented as Ileoileal, Ileocolic, Ileo-ileo-colic, and others.
Based on the surgery, the market has been segmented as surgery, drugs, and others.
Based on the end user, the market has been segmented as hospitals & clinics, academic and research, and others.
Based on the diagnosis, the market has been segmented as barium enema, ultrasound, X-ray, computerized tomography (CT), and others.
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Tuesday, 9 April 2019

Mortuary Refrigerator Market to show steady growth, 2019

Mortuary Refrigerator Market Scenario:
Mortuary refrigerators are the largely used equipment in the whole mortuary equipment market. These refrigerators have available with several features such as temperature adjustable knob, multiple chambers. Mortuary refrigerators are available in both positive and negative temperature facility. The positive temperature refrigerator slows down the degradation process of dead bodies for a period of time, and the negative temperature mortuary refrigerators are used to storage the body by freezing it and prevent degradation for longer duration. The increase in technology and rising demand for automation in mortuary procedures is one of the reasons for the larger share of the market.
The global mortuary refrigerator market is expected to register a CAGR of 4.3% during the forecast period of 2018 to 2023.
Mortuary refrigerators are used to keep dead bodies as a solution to maintain hygiene requirements in hospitals. The key factors contributing for the market growth are growing number of cancer patient and cancer-related research, increasing organ transplant, and growing demands for automation in mortuary procedures. Also, the increasing geriatric population, is contributing to drive the market. According to the United Census Bureau, the global-female-geriatric population is estimated to reach 4,139 million by 2030 from 3,601 million in 2015. However, the minimal awareness about mortuary equipment and fluctuating prices of raw materials and substituting products for mortuary refrigerators hinders the market growth.
There are several companies involved in manufacturing of mortuary refrigerators with advanced features and ease to use. However, the cost of mortuary refrigerators compare to other mortuary related products and presence of alternative products in the market are hindering the market growth.
Global Key Players
  • LEEC
  • Hygeco
  • Paragon scare Ltd.
  • Thalheimer Kühlung
  • Barber Medical
  • CEABIS
  • EIHF Isofroid
  • EVERmed
  • Fiocchetti and Funeralia
Segmentation
The global mortuary refrigerator market is segmented on the basis of product type, application, application, end user, and region.
On the basis of product type, the market is segmented into positive temperature, negative temperature refrigerators.
By application, the market is categorised into corpses storage and forensic investigation. On the basis of end-user, the global mortuary refrigerator market is categorised into forensic labs, research and academics, funeral homes, hospitals and clinics, and others.
Regional Market Summary
The Americas dominates the global market for mortuary refrigerator owing to the increase in cancer and cancer-related research activities, increasing number of geriatric populations with health-related problems and presence of major market players within the region boosts the market growth. According to the Administration for Community Living in 2016, the number of older women within the region was estimated to be 26.7 million. Furthermore, the presence of developed economies and regulations by various authorities in healthcare sector within the region boosts the market growth.
In 2017, it was estimated that Europe stood second in the global mortuary refrigerator market. The increase in demand for mortuary refrigerator by forensic labs and hospitals to store the dead bodies for investigation increases the market growth. These equipment’s are also, used to store the entire body donated for medical research purpose, which are used in medical colleges to teach human anatomy.
Asia Pacific was the fastest growing region for the global mortuary refrigerator market in 2017. Factors such as increasing awareness about the advanced and innovative mortuary refrigerator, growing regulations and policies by various authorities regarding the hygiene in hospital drives the market growth.
On the other hand, the Middle East and Africa holds a least share in the global mortuary refrigerator market due to the lack of awareness about the advanced mortuary procedures and mortuary refrigerator hinders the market growth in this region.
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Top trends in Leukemia Therapeutics Market by 2019

Leukemia is blood cancer which most commonly in adults and children. Acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia are the major types of the leukemia. Leukemia therapeutics are used in treating the leukemia.
The global leukemia therapeutics anticipated to have held a market value of USD 10.7 billion in the year 2017 and is expected to grow at a CAGR of 5.3% during the forecast period.
Segmentation
The global leukemia therapeutics market has been segmented into type, applications, and region.
Based on type, leukemia therapeutics market is segmented into chemotherapy, biological therapy, targeted therapy, radiation therapy, and stem cell transplant. The chemotherapy segment is expected to account for the largest share segment of the market in 2017. Chemotherapy segment further sub segmented into alkylating agents, antimetabolites, antitumor antibiotics, and others.
Based on applications, leukemia therapeutics market is segmented into acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia, and others. The acute lymphocytic leukemia segment is expected to account for the largest share segment of the market in 2017.
Regional Market Summary
Geographically, the Americas is anticipated to dominate the global leukemia therapeutics market owing to a well-established player, innovative therapies to drive the market for leukemia, increase prevalence of leukemia, and increasing older population.
Europe is expected to hold the second largest position in the global leukemia therapeutics market. The market growth in this region is attributed to increase prevalence of leukemia.
The leukemia therapeutics market in Asia-Pacific region consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia-Pacific. The Asia-Pacific region is expected to be fastest growing region.
The Middle East & Africa has the least share of the leukemia therapeutics market.
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Plasma Fractionation Market Anticipated To Witness Noteworthy Growth in the Coming Years

Increasing prevalence of immunodeficiency disorders and rising healthcare expenditure are also boosting the plasma fractionation market in the US region. According to the 2018 study published in the Allergy, Asthma & Clinical Immunology journal, the estimated overall prevalence of immunoglobulin A (IgA) deficiency in the US was approximately 1 in 300 to 1 in 500 persons.
In plasma fractionation process protein products are fractionated from human plasma for the prevention, and treatment of life-threatening conditions such as congenital deficiencies, immunologic disorders, and others.
Global plasma fractionation market is expected to grow significantly over the forecast period. It is anticipated that the market held a valuation of USD 18073 million in 2017 and is projected to grow at a CAGR of 6.5% over the forecast period.
Various other factors such as increasing geriatric population, technological advancements, emerging markets in APAC and RoW, rising plasma collection, and increasing prevalence of respiratory and autoimmune disorders are also expected to propel the growth of the market.
However, the emergence of recombinant alternatives, high cost of advanced products, and unfavourable reimbursement policies can hamper the market growth over the forecast period.
Segmentation
The global plasma fractionation market is segmented based on product, application, end user, and region.
The global market for plasma fractionation, by product is segmented into immunoglobulin, coagulation factor concentrates, albumin, protease inhibitors, and others. The immunoglobulin segment is further classified as intravenous immunoglobulin (IVIG), subcutaneous immunoglobulin (SCIG), and others. The coagulation factor concentrates segment is further classified as Factor VIII, Factor IX, Von Willebrand Factor, Prothrombin Complex Concentrate, Fibrinogen Concentrates, and Factor XIII.
Based on application, the market is segmented into immunology, neurology, hematology, critical care, pulmonology, rheumatology, hemato-oncology, and others.
Based on end user, the market is segmented into hospitals & clinics, clinical research laboratories, academic institutes, and others.
In the current scope of the study, the above-mentioned segments are covered into the four global regions, namely the Americas, Europe, Asia-Pacific and the Middle East & African region.
The plasma fractionation market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.
The European plasma fractionation market has been segmented into Western Europe and Eastern Europe. Western Europe has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.  The plasma fractionation market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The plasma fractionation market in the Middle East & Africa has been segmented into the Middle East and Africa.
Regional Market Summary
The Americas dominated the global market for plasma fractionation owing to the presence of major market players and increasing prevalence of immunodeficiency disorders within the region. According to the 2018 study published in the Allergy, Asthma & Clinical Immunology journal, the estimated overall prevalence of immunoglobulin A (IgA) deficiency in the US was approximately 1 in 300 to 1 in 500 persons.
In 2017, it was estimated that Europe stood second in the global plasma fractionation market. This can be attributed to the increasing technological advancements, and rising R&D investments.
Asia Pacific was projected to be the fastest growing region in 2017. Increasing healthcare expenditure drives the regional markets of the Asia Pacific region. According to the Australian Institute of Health and Welfare, from 2015 to 2016, the total health expenditure was USD 181 billion. Out of this, USD 69 billion was spent on hospitals, which is a real increase of USD 2 billion from the previous year. During the same years, non-government sources spent USD 55.8 billion on health.
On the other hand, the Middle East and Africa held least share in the global plasma fractionation market due to inadequate economic development, especially within the African region.
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Atherectomy Devices Market size and Key Trends in terms of volume and value 2019

Market Scenario
The global atherectomy devices market is projected to grow significantly over the forecast period. It is estimated that the global atherectomy devices market is expected to register a CAGR of 6.12% during the forecast period of 2018–2023, with an estimated market value of 1.09 billion in 2017. Atherectomy is a minimally invasive endovascular surgery technique. Atherectomy devices, such as catheters are used to remove atherosclerosis from the blood vessels.
The rising demand for minimally invasive technologies, coupled with the increase in the coronary and peripheral arterial diseases is expected to drive the growth of the market. Also, the high efficiency rate of the atherectomy devices is estimated to boost the growth of the intraocular lens market. According to the data published in 2015 by the Centers for Disease Control and Prevention (CDC), about 7,35,000 Americans have a heart attack annually. Factors such as post-operative complications, and lack of skilled medical professionals are limiting the growth of the market.
Moreover, major companies in the market are involved in new product launches to strengthen their position in the market. For instance, in June 2018, Biomerics, a medical device contract manufacturer announced the acquisition of FutureMatrix Interventional, Inc. The company aims to expand its portfolio of interventional catheters used in cardiovascular and urology fields, thus strengthening its position in the market.
Segmentation
The global atherectomy devices market is segmented on the basis of product type, application, and end user.
Based on application, the atherectomy devices market is segmented into cardiovascular, neurovascular, peripheral vascular, and others.
The atherectomy devices market, by product type is categorised into directional atherectomy systems, orbital atherectomy systems, photo-ablative (laser) atherectomy systems, rotational atherectomy systems, and others.
The directional atherectomy systems segment is expected to hold the largest share owing to the high treatment rate, whereas the photo-ablative (laser) atherectomy systems is expected to be the fastest growing segment owing to the growing preference by surgeons.
On the basis of end user, the market is segmented into hospitals, ambulatory surgery centers, and others.
On the basis of region, the global atherectomy devices market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas is sub-segmented into North America and Latin America. The North American region is further segmented into the US and Canada. The European region is divided into two, namely, Western Europe and Eastern Europe. Western Europe is further classified into Germany, Italy, France, the UK, Spain, and the rest of Western Europe. The Asia-Pacific region is sub-segmented into Japan, China, India, Australia, South Korea, and the rest of Asia-Pacific. The atherectomy devices market in the Middle East and Africa has been segmented into the Middle East and Africa.
Regional Market Summary
Asia-Pacific was projected to be the fastest growing region for the global atherectomy devices market. This owes to the technological advancements resulting in the development of cost-effective atherectomy devices leading to high acceptance rate for the devices in the Asia-Pacific region. The Middle East and Africa holds the least share in the global atherectomy devices market due to the presence of economically diverse countries, and less initiatives taken by the government.
It is projected that the Americas dominated the global atherectomy devices market owing to the growth of the market in the North American region. This is largely attributed to the factors such as increase in research funding, and growing awareness about the high-end atherectomy devices among medical professionals. Europe is expected to hold the second largest share in the atherectomy devices market owing to growing healthcare infrastructure. Additionally, various initiatives by public and private organizations is anticipated to boost the growth of the atherectomy devices market.
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Dental Bone Graft Substitutes Market 2019 Share, Trend, Segmentation and Forecast to 2023

Global dental bone graft substitutes market is expected to grow significantly over the forecast period. It is anticipated that the market held value of USD 461.3 million in 2017 and is projected to grow at a CAGR of 9.4% over the forecast period.
The factors such as increasing incidence of oral diseases namely, dental caries and periodontal diseases and growing medical tourism in developing countries are expected to propel the growth of the market. However, lack of proper reimbursement and stringent regulations hamper the market growth over the forecast period.
Global Dental Bone Graft Substitutes, by Key Players
  • Biohorizons Iph, Inc. (US)
  • Geistlich Pharma AG (Switzerland)
  • Dentsply Sirona (US)
  • Institut Straumann AG (Switzerland)
  • Medtronic Plc (US)
  • Zimmer Biomet Dental (US)
  • Dentium (South Korea)
  • LifeNet Health (US)
  • Orthogen, LLC (US)
Segmentation
The global dental bone graft substitutes market has been segmented into type, application, and end user.
Based on type, dental bone graft substitutes market is segmented into allograft, xenograft, alloplast, and others.
Based on application, dental bone graft substitutes market is segmented into ridge augmentation, sinus lift, socket preservation, periodontal defect, and implant bone regeneration.
Based on end user, dental bone graft substitutes market is segmented into dental clinics, hospitals, and others. The dental clinics segment is expected to account for the largest share segment of the market in 2017.
The dental bone graft substitutes market segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The dental bone graft substitutes market in the Americas further segmented into North America and South America, with the North American market divided into the US and Canada.
The European dental bone graft substitutes market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.
The dental bone graft substitutes market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The dental bone graft substitutes market in the Middle East & Africa segmented into the Middle East and Africa.
Regional Market Summary
Geographically, Europe is anticipated to dominate the global dental bone graft substitutes market owing to a well-established player and increasing incidence of oral diseases namely, dental caries and periodontal diseases.
The Americas is expected to hold the second largest position in the global dental bone graft substitutes market. The market growth in this region is attributed to increasing incidence of oral diseases such as dental caries and periodontal diseases and growing ageing population.
The dental bone graft substitutes market in Asia-Pacific region consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia-Pacific. The Asia-Pacific region is expected to be fastest growing region. The market growth in this region is attributed to growing medical tourism in developing countries.
The Middle East & Africa has the least share of the dental bone graft substitutes market.
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