Sepsis Diagnostics Market - Granular Market Report and Review, 2019

Sepsis is a type of life-threatening organ dysfunction arises when the body's response to an infection injures its own tissues and organs. It can be caused due to weakened immune system, chronic illness, kidney or liver disease, cancer and severe wounds. It can be of two types severe sepsis when there’s organ failure and other is septic shock in which there are the symptoms of severe sepsis includes a low blood pressure. The hospital-acquired infections and rising prevalence of sepsis has led to a growing need for its early diagnosis, which is one of the driving factor for sepsis diagnostics market.

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The global market for sepsis diagnostics is expected to reach USD 710 million by the end of the forecasted period and is expected to grow at a CAGR of 8%.

Competitive Analysis

• bioMérieux, Inc.
• EKF Diagnostics
• Immunexpress
• T2 Biosystems, Inc.
• Becton
• Dickinson and Company
• Axis-Shield Diagnostics Ltd.
• Cube Dx GmbH
• Sandstone Diagnostics, Inc.

Study Objectives of Global Sepsis Diagnostics Market:

• To provide detail analysis of the market structure along with forecast for the next 7 years of various segments and sub-segments of the global sepsis diagnostics market.
• To provide insights about factors affecting the market growth.
• To analyze the market based on various factors which includes price analysis, supply chain analysis, Porters Five Force Analysis etc.
• To offer past as well as estimated future revenue of the market’s  segments and sub-segments with respect to four main geographies and their countries; these includes  Americas, Europe, Asia-Pacific, and Middle East & Africa.
• To provide country level analysis of the market with respect to the current market size and estimated future growth of the market.
• To give country level analysis of the market’s segments which includes by technology, by type of product, by end users and other sub segments.
• To provide overview about key players and their strategic profiling in the market; comprehensively analyzing their core competencies and drawing a competitive landscape for the market.
• To track and analyze competitive developments such as joint ventures, strategic alliances, mergers and acquisitions, new product developments, along with research and developments that is taking place globally.

Segmental Analysis

Global sepsis diagnostics market has been segmented on the basis of technology which comprises molecular diagnostics, biomarkers, immunoassays and others. On the basis of type of product product types; the market is segmented into kits, instruments, blood culture media and others. On the basis of end users the market is segmented into pathology laboratories, specialty clinics, hospitals, diagnostic centers and others.

Regional Analysis

Globally North America is the largest market for medical tourism. The North American market for sepsis diagnostics is expected to reach USD 320 million by the end of the forecasted period.

Europe is the second largest market for sepsis diagnostics which is expected to grow at the CAGR of 6.8%. Asia Pacific is expected to be fastest growing region in sepsis diagnostics market.

The report of global sepsis diagnostics market by Market Research Future comprises of extensive primary research along with detail analysis of qualitative as well as quantitative aspects by various industry experts and key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of the current market scenario which includes past and projected future market size in terms of value and volume, technological advancement, macro economical and governing factors in the market. Along with all these detail information and strategies about top key players in the industry is also given. Further a broad study of different markets segments and regions is also provided.

Industry Updates:

Dec 2018 Beckman Coulter, which is an international leader in the clinical diagnostics industry has announced that it is joining forces with Sepsis Alliance, the nation's leading sepsis organization, to support the Sepsis Coordinator Network. The pioneering online, peer-to-peer alliance for healthcare professionals, the Sepsis Coordinator Network is dedicated to saving lives by advancing patient results.

May 2018 Mobidiag, a Finnish firm, has obtained funding to creäte a rapid molecular sepsis assay on its Novodiag system. The fresh funding comprises of a €1.5 million ($1.74 million) loan for the first year of the project provided by Business Finland, a funding agency previously known as Tekes.

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Microbiology Testing Market Growth and Restrain Factors Analysis By 2023

Market Scenario

Market Research Future (MRFR) Says, The Global Microbiology Testing Market is expecting a more than twofold rise from USD 2706.1 million in 2016 to USD 5409.1 million by 2023. The extensively studied report covers the drivers that are going to impact the market decidedly during the forecast period (2014-2023) and delivers a much-precise predictive analysis of the coming years of the market. Infectious diseases are on the rise, and several outbreaks of epidemics across the globe have spurred the demand for microbiology testing. Healthcare segment is witnessing a significant increase in expenditure all over the world, and an increase in research allotments are a positive sign for the microbiology testing market.

Microbiology testing has emerged as one of the rapidly changing segment of healthcare over the past few years. Microbiology testing deals with the study of microbial germs and their clinical applications for the improvement of health. Increasing prevalence of various infectious diseases are driving the growth for global microbiology testing market.

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However, the market can witness a slight pullback caused by stringent regulatory frameworks, and patient reimbursement policies can impede the market growth for a short span of time. But the bottlenecked market can see a wider scope of possibility with improving technologies in the field of product enhancement which can ease the market growth considerably.

The key factor supporting the global microbiology testing market growth is the increasing prevalence of various infectious diseases. The global microbiology testing market has been segmented into application, end user, product type, and lastly, region. The application-based segmentation of this market comprises of gastrointestinal infections, respiratory infections, sexually transmitted infections, urinary tract infections, and others.

Key Players

The key players in the global microbiology testing market include Alere (USA), Beckman Coulter Inc. (USA), Becton Dickinson (BD) (USA), Biomérieux SA (France), Cepheid (USA), F. Hoffmann-La Roche Ltd (Switzerland), and Thermo Fisher Scientific Inc. (USA).

Latest Industry News

• Leading small molecule innovator and generic Active Pharmaceutical Ingredients (APIs) manufacturer Cambrex Corporation, who also specialize in finished dosage forms, has acquired Avista Pharma Solutions (“Avista”), a contract development, manufacturing, and testing organization, from Ampersand Capital Partners. Avista is also a microbiology testing leader. 2 JAN 2019
• Clear Safety, the flagship product of Clear Labs has received AOAC Performance Tested certification for Salmonella enterica Clear Labs is a unique automated and intelligent next-generation sequencing (NGS) platform purpose-built for food safety testing. Clear Safety combines advanced microbiology, data science, robotic automation, software analytics, and state-of-the-art NGS sequencing, to not only to lower the costs significantly but to also achieve greater than 99.9% accuracy. 4 DEC 2018

Segments 

Global Microbiology testing Market has been segmented on the basis of type which comprise Instruments, Chemicals & Reagents, Consumables & Accessories, and others. On the basis of application, it is segmented into, Gastrointestinal Infections, Respiratory Infections, Urinary tract Infections, Sexually Transmitted Infections, Others. On the basis of end user, it is segmented into, Hospital based laboratory, Independent laboratory, and Academics & Research Institutes.

Regional Analysis

The regional segmentation of the global microbiology testing market can segment the global market into regional markets by the names of Asia Pacific, North America, Europe, and the Middle East & Africa (MEA). In 2016, North America held the largest share market in the global market which was 37.9%. During the forecast period, North America is expected to continue as the largest regional market because the advanced medical facilities are available in this region and support from government regarding investment on the research & development (R&D) is available. The indispensable country-specific markets in this region are USA and Canada. Many key market players are based in North America, especially in the USA.

In 2016, Europe was the second largest microbiology testing market. During the forecast period, there are expectations regarding steady and positive market growth. However, Europe may not retain its spot by the end of forecast period. European government support R&D investment in the medical sector and in terms of technological advancement in the medical sector, Europe is second only to North America. This makes Europe an important regional market. The most significant country-specific markets in this region are France, Germany, Italy, Spain, and the UK, followed by the remaining countries of Europe.

Right now, Asia Pacific is the second largest and fastest growing market in the global microbiology testing market this is to continue till the end of forecast period. This market is expected to grow at 12.1% CAGR between 2017 and 2023. The priority country-specific markets in this region are Australia, China, India, South Korea, and Japan, followed by the remaining countries of the Asia Pacific region.

The MEA region has the least market share due to poor countries, lack of awareness, lack of education, low standard of medical facilities, lack of advanced technology, lack of healthcare facilities, and majority governments not considering healthcare a priority. In this region, the primary country-specific markets are Egypt, Saudi Arabia, and UAE, followed by the remaining countries of the MEA region.

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Age-Related Macular Degeneration Market Segmentation Detailed Study with Forecast Up To 2019

Market scenario:

This MRFR study offers a vivid view of the global age-related macular degeneration AMD market. The study includes an in-depth analysis of macro and micro-economic factors likely to influence the market during the forecast period. It further summarizes the key market opportunities and trends.

As per the study offered by Market Research Future (MRFR), the global age related macular degeneration market is set to expand at a CAGR of 8.3% during the forecast period 2018 to 2023. The valuation of the market is predicted to grow from USD 1.37 Bn at the end of 2017 to 2.21 Bn by 2023-end. The growing patient pool of a geriatric population is leading the expansion of the market. It is estimated that AMD contributes significantly towards visual loss among the elderly population. In addition, the global aging population is expected to get doubled by the end of 2020. It is presumed to aid the proliferation of the age related macular degeneration market over the assessment period.

Regionally, the Americas age-related macular degeneration market is segmented into two major regions, namely, North America and South America.

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The market is lucrative at present, and the rising awareness about the diseases is further expected to boost the growth trajectory of the age related macular degeneration market in the foreseeable future. On the flip side, unfavorable reimbursement policies and the high cost of drugs remain impediments to the market growth.

The expiry of drug patents for widely accepted branded drugs have opened new avenues of growth opportunities for the market participants. Investments are prognosticated to flow towards the development in the formulas of existing drugs for enhanced efficiency. In addition, expired drug patents have paved the way for a reduction in price points, thus, augmenting the global age related macular degeneration market.

Competitive Dashboard:

• Regeneron Pharmaceutical Inc.,
• Rxi Pharmaceuticals,
• Hoffmann-La Roche AG,
• Santen Pharmaceuticals
• Bayer AG,
• Pfizer Inc.,
• Allergan,
• Novartis AG,
• Bausch & Lomb Incorporated,
• Alimera Sciences.

Market Segmentation:

By type, the global age related macular degeneration market has been segmented into wet AMD and dry AMD.

By diagnosis & treatment, the age related macular degeneration market has been segmented into treatment and diagnosis.

By route of administration, the global age related macular degeneration market is segmented into intravitreal, intravenous, and others.

By stages, the age related macular degeneration market has been segmented into intermediate AMD, early AMD, and late AMD.

By age group, the global age related macular degeneration market has been segmented into above 75, above 60, and above 40.

By end-user, the age related macular degeneration market has been segmented into hospitals & clinics, diagnostic centers, academic research institutes, and others.

Regional Analysis:

The age related macular degeneration market, by region, has been segmented into Americas, Europe, Asia Pacific, and the Middle East & Africa. The Americas is projected to hold a dominant share of the global market through the forecast period. The rising burden of the disease in the region is expected to drive the proliferation of the regional market. According to the Centers for Disease Control and Prevention (CDC), 1.8 million people were suffering from the disease in 2015 in the U.S.

Europe is an important growth pocket placed at the second position in the marketplace. It is predicted to benefit from rising geriatric population and increasing healthcare expenditure. Meanwhile, Asia Pacific is likely to emerge as the fastest growing regional market for AMD over the assessment period. The factors that are responsible for favoring the expansion of the age-related macular degeneration market in the region are rising healthcare expenditure, increasing prevalence of eye-disorders, growing geriatric population, etc.

Industry News:

In November 2018, the European Court of Justice has determined that Avastin by Roche can be reimbursed for the treatment of age-related macular degeneration despite the challenge imposed by Bayer and Novartis.

In December 2018, the U.S. based Ophthotech Corp. has scrapped the clinical trials of C5 inhibitor for the treatment of wet age-related macular degeneration in spite of successful phase 2a results exhibiting tolerance for imura (avacincaptad pegol) in combination with ranibizumab (Lucentis).

In December 2018, a team of British scientists has announced that they are piloting an eye drop aimed at treating age-related macular degeneration (AMD). The researchers have concluded successful trials on rabbits and pigs and will be tried on human eyes in 2019.

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Liquid Biopsy Market - Granular Market Report and Review, 2019

Market Insights:

Liquid biopsy overcomes these problems of tissue biopsy by using biomarkers present in samples such as blood, urine etc. and thus is a comparatively non-invasive technique. Liquid biopsy also provides greater information about the sample which is real time. The real time data can be used for monitoring and thereby determining the treatment for diseases such as cancer. The greater sensitivity of tissue biopsy coupled with the development of sophisticated detectors with extremely low detection rates have enabled the early detection of diseases which is the holy grail of cancer.

Biopsy involves extracting a sample of tissue and testing it for the presence of diseases especially cancer. Traditional tissue biopsy is a painful technique and also has a high rate of false results. Moreover the technique is costly, time consuming and not applicable for extracting samples such as those close to vital organs such as heart.

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Segmentation:

Global Liquid Biopsy market has been segmented on the basis of biomarker type which comprises of circulating tumor cells (Ctcs), circulating tumor DNA (Ctdna), extracellular vesicles (Evs) and other biomarker. On the basis of application; market is segmented into cancer therapeutic application, reproductive health, and other therapeutic application. On the basis of sample; market is segmented into blood, urine and others. On the basis of end-users; market is segmented into hospitals and laboratories, academic and research centres and others.

Major Players

• Guardant Health, Inc.,
• Trovagene, Inc.,
• RainDance Technologies, Inc.,
• Agena Bioscience Inc. Inc.,
• Admera Health,
• Biocept, Inc.,
• Circulogene Theranostics,
• Inivata Ltd.,
• SAGA Diagnostics AB,
• Exosome Diagnostics and others.

Drivers

The market drivers for the liquid biopsy market are rising rates of cancer, growing investment in research and development, collaborations between companies and public organizations, rise in geriatric population, rising expenditure on health etc. The factors which are inhibiting the growth of the market includes the prohibitive costs associated with liquid biopsy and the differential awareness and availability between developing and the developed world. However, not all cancer patients benefit from early detection as some cancer types such as brain cancer and prostate cancer may lie dormant for many years. Further liquid biopsy is not all non-invasive as can be seen in case of using spinal fluid as sample.

Also the technique is not applicable to all types of cancer as some cancers such as brain cancer and prostate cancer may lie dormant for many years, and thus are either undetectable or detected very late which robs liquid biopsy of its advantages. Further liquid biopsy is not all non-invasive as can be seen in case of using spinal fluid as sample.

Regional Analysis:

Depending on geographic region, Liquid biopsy market is segmented into four key regions: Americas, Europe, Asia Pacific, and Middle East & Africa. Globally developed countries led by North America is the largest market for Liquid biopsy. Europe is the second-largest market for liquid biopsy. The developing regions market such as Asia pacific region and Middle East & Africa however is rising much faster.

Key findings

• Circulating tumor cells (CTCs) segment dominates both in terms of market share as well as revenues, contributing approx. 55.48% of the revenue share of the liquid biopsy market.
• On the basis of the therapeutic application, the segment for Cancer will reflect the highest growth potential, with over 82.83% of the market share by revenues. However, the urine sample segment is anticipated to witness noticeable growth.
• The market for liquid biopsy is dominated by North America and Europe and this trend will continue. Asia-Pacific market is the fastest growing market and is expected to grow at a CAGR of 29.7% during forecasted period

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Chemotherapy Market Segmentation Detailed Study with Forecast Up To 2019

According to the analysis offered by Market Research Future (MRFR), The Global Chemotherapy Market is Expected to register a CAGR of 11.50% to reach USD 56,491.59 Million by 2024.

Chemotherapy is one of the types of cancer treatment, which includes the use of one or more chemotherapeutic agents such as anti-cancer drugs. The treatment prevents the division of cancer cells and the growth of cancer cells by killing dividing cells. It is used for the treatment of various types of cancers such as lung cancer, breast cancer, leukemia, myeloma, sarcoma, lymphoma, ovarian cancer, and others.

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The increasing prevalence of cancer, increasing expenditure on oncology medicine and research, and reimbursements and growing health insurance are driving the growth of the global chemotherapy market. 

Market Dynamics

The global chemotherapy market has been largely benefited by the increasing demand for chemotherapy products across the world. Increasing prevalence of cancer; increasing expenditure on oncology medicine and research, and reimbursements and growing health insurance are expected to spur market growth during the forecast period. Moreover, the patent expiry of leading drugs, government initiatives, and increasing public awareness about various diseases and treatment options are further expected to boost the growth of the global chemotherapy market during the review period.

Segmentation

The Global Chemotherapy has been segmented into major four segments, including drug class, route of administration, indication, and end user.

On the basis of drug class, the market is segmented into alkylating agents, mitotic inhibitors, antimetabolites, topoisomerase inhibitors, and antitumor antibiotic. The alkylating agents segment is expected to lead the market and register a substantial CAGR to reach USD 20,360.32 million by the end of 2024 and projected to exhibit the highest CAGR of 11.83% from 2019 to 2024.

Furthermore, based on indication, the market is segmented into lung cancer, breast cancer, colorectal cancer, prostate cancer, stomach cancer, lymphoma, leukemia, ovarian cancer, and others.  Lung cancer accounted for the largest market share and expected to grow with the CAGR of 11.88% during the forecast period.

On the basis of route of administration, the market is segmented into intravenous, oral, subcutaneous, intra-muscular, intravesicular, topical, intraperitoneal, and intraventricular/intrathecal. Intravenous accounted for the largest market share. However, the oral segment is expected to grow at the fastest CAGR of 11.95% during the forecast period.

On the basis of end user, the market is segmented into, specialty centers, hospitals & clinics, others

Key Players

The prominent players in the global chemotherapy market are Johnson & Johnson Services Inc (US), GlaxoSmithKline PLC (UK), Eli Lilly and Company (US), F. Hoffmann-La Roche Ltd (Switzerland), Novartis AG (Switzerland), Pfizer Inc. (US), Merck & Co. Inc. (US), Sanofi S.A. (France), Celgene Corporation (US) and Bristol-Myers Squibb Company (US).

Regional Analysis

Geographically the chemotherapy market is divided into the Americas, Europe, Asia-Pacific, and the Middle East and Africa.

Americas accounted for the largest market share of 41.04% in 2018, and the regional market is projected to register a CAGR of 10.88%during the forecast period. North America is one of the leading markets in the region, accounting for the largest market share during the review period.  

The European market is estimated to exceed USD 18,292.73 Million by 2024. The accessibility to advanced treatment facilities, rising government initiatives to promote research to find a cure to the increasing number of cancer cases, and growing healthcare expenditure are driving the growth of the chemotherapy market in the region. Germany is the major contributor to the growth of the regional market, followed by France.

The market in Asia-Pacific is expected to be the fastest growing market. This high growth is mainly attributed to the increasing R&D funding by developing countries such as China and India for the development of the healthcare sector. Various other factors that influence the growth of the market include growing incidence of cancer, aging population, increasing demand for advanced therapies, patent expiry of leading drugs, government initiatives, and increasing public awareness about various diseases and treatment options.

The Middle East & Africa commands the least market share of the chemotherapy market, owing to fewer developments and extremely low income but, is expected to grow with better chemotherapy treatments. As the population is rapidly aging, cancer treatment is expected to increase in this region

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Stroke Disorder and Treatment Market 2019 Market Challenge, Driver, Trends & Forecast to 2023

Market Scenario

The Global Stroke Disorder and Treatment Market is presumed to demonstrate a healthy CAGR during the forecast period (2016-2022) owing to the rising high blood pressure patients, asserts Market Research Future (MRFR).

Heart problems and brain problems are considered among most dangerous medical problems, and their treatments are considered to be most expensive. Heart strokes and brain strokes can strike any moment and can be fatal. Hence, the market offering treatment for it is always lucrative. Globally it is increasing rapidly. The major factor that drives the growth of this market is the increasing high blood pressure patients. Due to increasing alcoholism and patients with diabetes, cardiovascular diseases are increasing the growth of this disorder and the market offering its treatment.

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Stroke is referred to as the condition which occurs when clot is formed in the artery and oxygen supply is cut off. Brain cells thus get deprived of oxygen and start to die. Heart and brain strokes can strike any moment and can be fatal. Stroke is considered as one of the leading causes of death across the world with higher prevalence in the geriatric population.

Competitive Dashboard

·         AstraZeneca (U.K),

·         Bayer Pharma AG (Germany),

·         Novartis AG (Switzerland),

·         Daiichi Sankyo (Japan),

·         Pfizer (U.S).

Drivers and Constraints Impacting the Market

With increasing consumption of alcohol and diabetic patients, the global stroke disorder and treatment market is likely to flourish. Also, the increasing prevalence of cardiovascular diseases is highly influencing the market across the globe. Brain problems and heart problems are considered as the most dangerous medical issues across the world with expensive medication and treatments. Thus, the market offering treatment for it is lucrative. The market is further accelerated by the huge patient pool along with rising geriatric population across the globe. Moreover, atrial fibrillation, hypertension, and coronary heart diseases are contributing to the growth of the market.

On the flip side, high cost of treatment adversely affects the growth of the market. Moreover, the lack of transparent reimbursement scenario is also likely to dampen the stroke disorder and treatment market during the assessment period.

Global Stroke Disorder and Treatment Market: Segmental Analysis

The global stroke disorder and treatment market has been segmented on the basis of type, medicine, treatment, and region.

By mode of type, the global stroke disorder and treatment market has been segmented into ischemic stroke and hemorrhagic strokes. Among these, the weakened blood vessel leakage is referred to as hemorrhagic stroke. Ischemic stroke generally occurs due to an obstruction within a blood vessel which supplies blood to the brain.

By mode of medicine, the global stroke disorder and treatment market has been segmented into anticoagulants/antiplatelet, anti-hypertensive.

By mode of treatment, the global stroke disorder and treatment market has been segmented into tissue plasminogen activator (TPA), carotid endarterectomy, surgical treatment, endovascular procedures, and others. TPA is referred to as an enzyme involved in the breakdown of blood clots and dissolves them. It is a less invasive procedure and is used for treating problems affecting the blood vessels like aneurysm.

Regional Insights

Geographically, the stroke disorder and treatment market span across regions namely, Europe, North America, Asia Pacific, and Rest-of-the-World.

Among these, the North America region is presumed to dominate the stroke diagnostics and therapeutics market and is likely to maintain its dominance. The growth is attributed to the rising awareness among the population regarding the symptoms of stroke followed by the several harmful effects associated with high glucose level in blood. With technological advancements and high-end research, and rising public interest, the demand for stroke disorder and treatment is likely to trigger in the coming years. Moreover, encouraging healthcare infrastructure and higher healthcare expenditure are some of the major factors contributing to the growth of the stroke disorder and treatment market.

European holds the second-largest position with high diabetic population. Moreover, the growing percentage of diabetes mellitus population is directly proportionate to the associated risk of stroke in individuals, thereby contributing to the market growth during the assessment period. Additionally, technological advancements and healthcare research are further influencing the market growth.

Industry Updates

CERENOVUS business has recently launched the single largest global registry, the EXCELLENT Registry, in order to collect and analyze stroke-inducing blood clots removed from the brain with its EMBOTRAP II Revascularization Device. The EXCELLENT Registry is likely to enroll up to 1000 ischemic stroke patients in as many as 50 clinical sites in Europe and the United States.

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Detailed Table of Contents:

1. Report Prologue

2. Introduction

2.1 Definition

2.2 Scope Of The Study

2.2.1 Research Objective

2.2.2 Assumptions

2.2.3 Limitations

2.3 Market Structure

2.4. Market Segmentation

3. Research Methodology

3.1 Research Process

3.2 Primary Research

3.3 Secondary Research

3.4 Market Size Estimation

3.5 Forecast Model

4. Market Dynamics

4.1 Drivers

4.2 Restraints

4.3 Opportunities

4.4 Mega Trends

4.5 Macroeconomic Indicators

5. Market Factor Analysis

5.1 Value Chain Analysis

5.2 Porters Five Forces Analysis

5.3 Demand & Supply: Gap Analysis

5.4 Pricing Analysis

5.5 Investment Opportunity Analysis

5.6 Merger And Acquisition Landscape

...TOC Continued!

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Anti-Hypertensive Drugs Market Segmentation Detailed Study with Forecast Up To 2019

According to a recent study report published by the Market Research Future, The global market of  Anti-Hypertensive Drugs was valued at $32.2 billion in 2015, and is projected to reach $ USD 41.2 billion by 2023. Thus the market is anticipated to observe a sluggish growth; at a CAGR of 2.73% during 2016 to 2022.

Competitive Analysis

Key players in the antihypertensive drugs market are Sanofi S.A. (France), Novartis AG (Switzerland), AstraZeneca (U.K.), Daiichi Sankyo Company, Ltd. (Japan), Boehringer Engelheim GmbH (Germany), Takeda Pharmaceutical Company (Japan), Merck KGaA (Germany), Johnson & Johnson Services, Inc. (U.S.), Bayer AG (Germany), Pfizer, Inc. (U.S.), and United Therapeutics Corporation (U.S.). The market is characterized by expiry of various patented drugs and entry of generics. Players are taking measures to regain their lost standing by investing in research and development and launch of new products.

Anti-Hypertensive Drugs are used to treat hypertension (high blood pressure). Hypertension is a state of chronic elevated arterial blood pressure at or greater than 140/90 mm Hg for adults. Hypertension is one of the most powerful risk factors for cardiovascular morbidity and mortality. There exact cause of hypertension is unknown but is said that unhealthy, heady lifestyle and ageing mirror such disorders as “Hypertension”.

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The major market driving factors for secondary hypertension are greater detection and early diagnosis. Rise in the prevalence diseases such as kidney problems, thyroid problems, adrenal gland tumours, heart ailments, chronic alcohol use etc. in which anti-hypertensive drugs are used; are some of the other factors driving the growth of the Anti-Hypertensive Drugs market. The constraints however are overwhelming and include patent expiries such as Actelion's Tracleer (2015), and United Therapeutic's Remodulin (2014). Other blockbuster’s such as Novartis's Diovan and Exforge, Sanofi Aventis's Avapro (2012) etc are also off-patent.

Many antihypertensive drugs have their primary action on systemic vascular resistance. Some of these drugs produce vasodilation by interfering with sympathetic adrenergic vascular tone (sympatholytics) or by blocking the formation of angiotensin II or its vascular receptors. Other drugs are direct arterial dilators, and some are mixed arterial and venous dilators. Although less commonly used because of a high incidence of side effects, there are drugs that act on regions in the brain that control sympathetic autonomic outflow. By reducing sympathetic efferent activity, centrally acting drugs decrease arterial pressure by decreasing systemic vascular resistance and cardiac output.

Some antihypertensive drugs, most notably beta-blockers, depress heart rate and contractility (this decreases stroke volume) by blocking the influence of sympathetic nerves on the heart. Calcium-channel blockers, especially those that are more cardioselective, also reduce cardiac output by decreasing heart rate and contractility. Some calcium-channel blockers (most notably the dihydropyridines) are more selective for the systemic vasculature and therefore reduce systemic vascular resistance.

Segmentation

The Anti-Hypertensive Market can be segmented in to 4 key dynamics for the convenience of the report and enhanced understanding;

Segmentation By Pharmacological Class               : Comprises Diuretics, ACE Inhibitors, Calcium Channel Blockers, Adrenergic Blocker and other.

Segmentation By Hypertension Type                      : Comprises Systemic and Pulmonary Hypertension Drugs and other.

Segmentation By Disease Source                              : Comprises Primary and Secondary.

Segmentation By Regions                                            : Comprises Geographical regions - North America, Europe, APAC and Rest of the World.

Regional Analysis

The antihypertensive drugs market covers growth drivers in the following regions, namely Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA). The Americas accounted for a large market share owing to high prevalence of hypertension linked to cardiovascular and renal disorders. Drives by government and non-government organizations for creating awareness of the medical condition are likely to bolster the revenue of the antihypertensive drugs market in Americas.

The Europe region was the second-largest due to rise of cardiovascular diseases, unhealthy diets, and increase noticed in obesity levels of patients. According to the European Heart Network in 2017, heart diseases accounted for 3.9 million deaths. Germany, France, and the U.K. are expected to be the prime contributors to the antihypertensive drugs market in Europe.

The APAC region is projected to exhibit a robust pace owing to increased healthcare budget and rise in disposable income levels of patients. The setup of research and development centers to fast-track the commoditization of drugs for treating hypertension is likely to boost the APAC antihypertensive drugs market.

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