Over-The-Wire Micro-Guide Catheter Market Professional Overview 2019-2023 With Major Vendors Size, Shares And Worldwide Demand

Market Highlights

Over-the-wire Micro Guide Catheter (OTW Micro Guide Catheter) is a thin tubular Medical device inserted into the body for diagnosis or treatments of diseases like cardiovascular, neurovascular, and urology. Specially designed to ease complex procedures, OTW Micro Guide Catheter combining excellent cross-ability and optimal guide-wire support, can effectively treat challenging cases involving tortuous vessels, CTO (chronic total occlusions), bifurcations, and highly stenosed and calcified lesions, giving the high success rate.

OTW Catheters are widely used in cardiovascular applications such as peripheral and coronary interventions and neurovascular interventional applications. The high success rate associated with the use of these catheters further augments its uptake and demand, resultantly driving its market growth.

According to Market Research Future (MRFR), the global Over-the-wire Micro Guide Catheters market is expected to grow at a CAGR of 9.37% during the forecast period (2018–2023).

According to reports published by the Centers for Disease Control and Prevention, the coronary heart disease is the most common type of heart diseases that accounted for the death of about 366,000 people in 2015.

Over-the-wire catheters comparatively make a better choice to treat a brain aneurysm than the rapid exchange catheters owing to their capabilities of extra pushing to enter stenose vessels, and additional support that they provide.

The increasing occurrences of coronary heart diseases, neurovascular diseases, hypertension, and other metabolic disorders, raising awareness for health, advancement in technologies, good healthcare infrastructure, and favorable reimbursement policies are fueling the market growth. 

Regional Analysis

The global over-the-wire micro guide catheters market is segmented into four regions: the Americas, Europe, Asia Pacific, and the Middle East & Africa. Americas is the global market leader for over-the-wire Micro-guide catheters. As per the study published in the Surgical Neurology International in 2017, it was found that more than 3% population of the United States equivalent to nearly 10 million individuals have a brain aneurysm. North America commands for the major share of the market whereas; South America show the fastest growth of the market due to the presence of boundless growth opportunities.

Europe OTW Micro Guide Catheter market holds the second position, globally. This is primarily attributable to the increasing prevalence of obesity as well as the increased incidence rate of hypertension and diabetes, which in turn is escalating cardiovascular traumas and cardiac arrest. Each year 15% of deaths in Europe occur due to cardiovascular diseases claims a study conducted by European Society of Cardiology.

The Asia Pacific region is the fastest growing market for the over-the-wire micro guide catheters. The region presents significant growth opportunities for market players as local policy makers continue to restructure the policy framework for the healthcare sector.

Global OTW Micro Guide Catheter Market: Segmentation

The global over-the-wire micro guide catheters market is segmented on the basis of applications and end-users. On the basis of applications, it is segmented into cardiovascular and neurovascular. By the cardiovascular, it is segmented into angiography, angioplasty, peripheral stenting, and others. On the basis of the neurovascular, it is segmented into intracranial aneurysms, percutaneous neurointerventional procedures, and others. Based on end-user the market is segmented into hospitals & clinics, ambulatory surgical centers, research & academic institutes, and others.  

Major Players in the Over-the-wire Micro Guide Catheters Market

Enki – Microtubes, Cardinal Health, DePuy Synthes, Koninklijke Philips N.V, Penumbra Inc., Terumo Europe N.V., Integer Holdings Corporation, Merit Medical Systems Inc., Teleflex Incorporated, Cook Medical, Boston Scientific Corporation, Asahi Intecc Company Limited, and Medtronic plc.

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Herbal Medicine Market Report By Global Industry Trends And Forecast The Upcoming Opportunities And Demand Till 2023

The Herbal Medicine market is estimated to be valued at USD 1,29,689.3 million by 2023 and expected to grow at a CAGR of 5.88% during the forecast period. The growing prevalence of cancer and infectious diseases across the globe, improving healthcare infrastructure, and skilled professionals are driving the growth of hospital and retail pharmacies in the herbal medicine market. The hospital & retail pharmacies segment accounted for the largest market share of 55.82% in 2017.

Various government organizations such as the National Institutes of Health (NIH) have increased the spending on the research of medicinal applications of various plants for the treatment of various chronic diseases such as cancer, arthritis, and many more. According to the National Centre for Biotechnology Information, the National Institutes of Health (NIH) spent USD 111,275,219 on all cannabinoid research in 2015. The increasing acceptance of herbal medicines globally and raising funds for their development are likely to support market growth.

Herbal medicines are used since ancient times for numerous health conditions. It is the oldest and most extensively used system of medicine in the world today. There are various kinds of herbal medicines and supplements used across the world. According to the National Center for Biotechnology Information, 2015, the World Health Organization (WTO), reported that around 70% to 80% of people globally rely on herbal sources for their treatment. Also, according to the American Botanical Council, September 2017, it was reported that in 2016, the sale of herbal supplements increased by 7.7% in the US. It was also estimated that consumers spending on herbal supplements increased to USD 7.452 billion in 2016. Thus, the increase in the demand for herbal products for healthcare purposes is likely to enhance this market during the forecast period. 

However, along with multiple applications, herbal medicines have some side-effects and allergic reactions such as dizziness, dry mouth, itching, erythematous lesions, and others. In some cases, they may cause kidney failure and liver damage to the patient. According to the National Center for Biotechnology Information 2017, 59.8% of people suffered from rash erythematous and 8.4% from allergic reactions after the use of herbal medicines. Also, according to the National Kidney Foundation 2017, herbal medicines are unsafe for patients having kidney problems because the kidney may not function properly and may create other complications after the consumption of herbal medicines. Thus, allergic reactions and adverse effects after the use of herbal medicines may affect market growth.

Segment analysis

Global herbal medicine market has been segmented on the basis of category, source, form, distribution channel, and region. On the basis of category, the market is divided into herbal pharmaceuticals, herbal dietary supplements, herbal functional foods, and herbal beauty products. The herbal pharmaceutical segment is growing owing to the increasing research and development on various herbs to find their medicinal properties, growing demand for natural medicines having fewer side-effects, and rising prevalence of chronic diseases such as diabetes, arthritis, cancer, sleep disorders, and digestive problems.

On the basis of form, the market has been divided into extracts, powders, capsules and tablets, syrups, and others.

On the basis of distribution channel, is segmented into hospital and retail pharmacies, e-commerce, and others. The hospital & retail pharmacies segment accounted for the largest market share in 2017. The growing prevalence of cancer and infectious diseases across the globe, improving healthcare infrastructure, and skilled professionals are driving the growth of hospital and retail pharmacies in the herbal medicine market.

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The Clear Aligners Market World Leading Key Players Revenue, Share, Analysis And Estimation Till 2025

The increasing level of acceptance and demand for clear aligners is amplifying the expansion of the market steadily. The benefits of clear aligners are multiplying the number of individuals who are opting for it. This is primarily due to the improving number of individuals electing for cosmetic dental procedures since the past few years. The market for clear aligners is expected to progress at a 20.80% CAGR while earning revenues worth USD 3982.30 Million in the duration of the forecast period. The evolution in terms of technology such as 3D printing, dental CAD software, and thermoforming machines is projected to transform the market favorably in the coming years.

The intensifying expansions witnessed in dental service organizations globally is forming a huge market share for clear aligners. The service delivery of these dental service organizations is a significant factor that is boosting the demand for clear aligners from various user groups globally. The soaring level of expenditure being directed towards healthcare is anticipated to create further scope for expansion of clear aligners. The advanced technology being adopted in various healthcare applications is expected to further add to the market’s expansion in the impending years. The spreading incidence of dental diseases and the growing preference for new treatment methods are estimated to have a substantial bearing in the clear aligners market worldwide. The proneness of the youth and older population to dental issues is expected to create a fairly stable demand for the market.

Furthermore, patients suffering from different dental alignment problems have also risen significantly, thus creating a sizable market segment for market growth. Also, the demand potential from the emerging economies around the world is projected to increase the progress of the clear aligners market in the approaching forecast period. However, the market for clear aligners can be hindered by factors such as the limitations involved in the use of clear aligners and the grey market for the distribution of clear aligners.
Competitive Analysis

The contenders shaping the clear aligners market are Align Technology, Inc., Dentsply Sirona, Institut Straumann AG, Clarus Company, Danaher Corporation, and 3M. A large number of companies are functioning in this market space and are also consistently developing better product varieties. The expansion of the operating units of market players is anticipated to motivate the progress of the market in the upcoming forecast period.

Segmental Analysis

The Global Clear Aligners Market has been segmented on the basis of age, product type, distribution channel, and region. The segmentation of the market on the basis of types of products comprise of medium type, hard type, and soft type. The product-type based segment is projected to develop at a rate of 20.80% through the forecast period and is assessed to be valued at USD 3982.30 million by 2023. The segmentation of the global clear aligners market on the basis of age groups is carried out on the basis of teenager and adult. The adult segment has the largest market share in terms of value and is growing to reach the projected valuation of USD 2996.59 Mn by the end of 2023. While the teenager segment is anticipated to increase at the highest CAGR of 21.90% in the forecast period.On the basis of distribution channel, the market for clear aligners is segmented into laboratories, direct sales, and others. The direct sales channel accounted for a market share of 78% in 2017 and is projected to touch USD 3185.47million by the year 2023. The segment is assessed to record a CAGR of 21.28% through the forecast period.

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Global Cranial Fixation and Stabilization Market Highlights With Leading Players By 2025

The Global Cranial Fixation and Stabilization Market is expected to reach USD 2.29 Billion by 2025, registering a CAGR of 8.90%.

This market growth can be attributed to the growing healthcare market and the ever-expanding technology market. Advances in these fields have created an environment that is conducive to the development of specialized surgical procedures for traditionally high-risk surgeries.

According to the UN, globally, one in six individuals suffers from a neurological disorder. There are several invasive surgeries that being developed to treat such conditions, requiring cranial fixation and stabilization equipment.

SEGMENTATION

By Category

Cranial stabilization equipment is used to secure the head during surgery, while cranial fixation implements are tools required to maintain the structural stability of the head and neck.

• Cranial Fixation Systems: Cranial fixation covers a wide array of tools and implements such as meshes, flap tube clamps, plates, and screws to be used during surgery. They are used predominantly for affixing bones, securing skin, and enhancing cranial integrity post-surgeries such as craniotomies.

• Cranial Stabilization Systems: Cranial surgeries are usually very delicate and complex, necessitating the use of equipment to immobilize the head. This is accomplished by the use of cranial stabilization equipment such as skull clamps and horseshoe headrests.

By Product

• Meshes: The leading market segment as 48% of all cranial injuries are maxillofacial. Over 52% of road accident-related injuries are mandibular fractures that require meshes.

• Skull Clamps: Ideal for prolonged surgeries that require patient immobilization for long periods with limited soft tissue damage. Used to hold the head firmly in place during surgery.

• Flap Tube Clamps: Used to attach cranial bones to the cranium during delicate surgeries when only a singular motion can be performed upon the afflicted area.

• Horseshoe Headrests: Used in cases where head movement is not to be completely restrained and soft tissue damage needs to be minimized.

• Plates: Used to seal gaping cranial wounds.

• Screws: Facilitate the attachment of cranial bones.

• Accessories: Include patient positioning systems and support systems.

By Type

• Resorbable: Materials that are eventually broken down by the body. The growth of the segment is limited by the high costs of the equipment.

• Non-Resorbable: These are biocompatible and offer unparalleled rigidity and stability to the cranium. Used extensively in developing countries due to their low costs.

By End User

• Hospitals: The segment commands the largest share of the global cranial fixation and stabilization market as most cranial surgeries are performed in hospitals. Cranial surgeries require the latest equipment and amenities, along with a high level of expertise, which are offered by hospitals.

• Ambulatory Surgical Centers: As emergency and temporary patient-stabilization surgeries are performed at these centers, the segment accounts for a small market share, which is somewhat offset by the higher revenue per surgery generated.

• Others: This segment includes on-site trauma and emergency surgeries. This is a niche segment with growth potential due to the establishment of trauma centers at industrial complexes.

 By Region

• Americas: Largest regional market, with North America accounting for 55% of the global market share.
• Asia-Pacific: Fastest growing regional market
• Europe: Second-largest market
• Middle East & Africa

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Liquid Biopsy Market Size, Share Analysis, Strategies, Revenue And Forecasts To 2022

Cancer diagnosis and monitoring have now become an important part of the healthcare system. The increasing burden of cancer has led to a need for development of new diagnostic and treatment methods. The researchers are now interested in determining the root cause of various types of cancer such as bone cancer, breast cancer, liver cancer, prostate cancer, and others. Furthermore, there is also need to introduce new diagnostic and treatment options due to increasing prevalence of rare cancer and late diagnosis of the diseases. Late diagnosis thus reduces the chances of curing the disease as it spreads throughout the body.

Liquid biopsy is one of the promising non-invasive method for the diagnosis of cancer. It involves the sampling of tissue in the liquid state. It is a simple and painless method for cancer diagnostic as compared to other diagnostics methods. Therefore, liquid as well as solid biopsy are important for cancer management, and creates excellent growth opportunities in the market. The technology is further applicable for monitoring cardiac and neurologic disease, early detection and evaluation of drug resistance, and prenatal testing. It can now be applied to organ transplant monitoring to bridge the gap between need of new technology, and rising demand.
Driver & Restrains
Increasing awareness about personalized cancer care is ruling the global liquid biopsy market. The market is driven by increasing demand for non-invasive testing, increasing prevalence of cancer, and extensive research and development in the cancer diagnosis and treatment. The market is also driven by number of advantages of liquid biopsies such as quick analysis, identification of specific mutations, low cost, and r less labor required. Furthermore, rising awareness about the diagnosis of various types of cancer stimulate the market growth. However, tumor heterogeneity, remaining the biggest challenge in cancer research, may restrain the growth of the market.

Strategic Approaches by Key Players:

Guardant Health, Inc., Trovagene, Inc., Agena Bioscience Inc. Inc., Admera Health, Biocept, Inc., Circulogene Theranostics,  Inivata Ltd.,  SAGA Diagnostics AB,  Exosome Diagnostics, and Bio-Rad Laboratories, Inc., Agena Bioscience Inc. Inc. are major players in the liquids biopsy market. The key players in the market are focusing on the development of new diagnostics methods and tools, as well as various strategic approaches such as acquisitions, partnership, and collaboration. Fund raising for cancer research is one to the important tasks for the key players to development new diagnostics devices and technologies as well as hold their position in the market.

Guardant Health:

• In January 2017, Guardant Health Inc. and MD Anderson and announce partnership to make comprehensive liquid biopsy part of oncology standard of care.
• In September, 2016, Guardant Health Inc. expanded the distribution of Guardant360, a genomic cancer test, to gain grounds in the Middle East
• In June, 2016, Guardant Health Inc. and Oncotest-Teva entered into a distribution and marketing partnership for Guardant360 in Israel

Bio-Rad Laboratories, Inc.:

• In January, 2017, Bio-Rad Laboratories, Inc. acquired RainDance Technologies outreach next generation sequencing applications and strengthen their position in the area of Droplet Digital PCR.

These developments help to determine the growth of the market across the globe, which is significantly lighted by partnerships and geographical expansion.

Cancer Research and Liquid Biopsy:

In February 2016, Circulogene Theranostics entered into a research agreement with the University of Alabama Birmingham (UAB) Comprehensive Cancer Center.

In December 2015, for example, researchers at the San Antonio Breast Cancer Symposium reported the use of cfDNA liquid biopsies to evaluate the prognosis after treatment in breast cancer patients enrolled in two phase III clinical trials.

Additionally, researcher have now successfully applied liquid biopsy to determine the prognosis of patients with colon cancer in phase II. Therefore, increasing applications of liquid biopsy in cancer research is another important driver for the growth of the market.

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Dental Consumables Market Size, Share Analysis, Strategies, Revenue And Forecasts To 2024

DENTSPLY Implants, 3M, Straumann AG, Nobel Biocare Services AG., Zimmer Biomet, BIOMET 3i LLC, Sybron, Heraeus Kulzer, Ivoclar Vivadent and others are some of the prominent players at the forefront of competition in the Global Dental Consumables Market and are profiled in MRFR Analysis. 

Global Dental Consumables Market - Overview

Dental Consumables are a category of products that are used on patients by dental practioners to treat prevent, restore, diagnosis and emergency oral health issues. Dental consumables industry has thus flourished as a result of many factors such as rising expenditure on healthcare, increasing income, technological advancements in products etc.
Dental procedures are not just restricted to repairing or treating of dental diseases, another niche market in the dental industry is the cosmetic dentistry market, which is growing at a steady rate due to the reasons concerned with enhancing of the overall facial beauty among the masses and increased disposable incomes. Irregularities or dissatisfaction with the appearance of the mouth and the oral cavity can lead to a visit for the cosmetic dentistry purpose. Such treatments are not always just cosmetic, but it can lead to a better oral health for the overall longevity of a person.
Global Dental Consumables Market - Competitive Analysis

Among dental consumables, dental implants are one of the most common procedures for which patients travel to get the treatment. As per the cost ranging differently in various countries, there is sometimes a lot of difference observed between countries for the cost of the materials alone, such as dental implants. Globally, the demand for dental consumables is ever increasing, due to the changing demographics trends, increasing dental treatments, and other factors. There is also an increase in the competition among the countries as well as within the countries as more and more dental care units want to become prominent and a first choice for the patient. The dental consumables market has also been affected due to the cosmetic dentistry market, which has shown a staggering growth in the recent years. Increasing awareness among the people for the well-being of oral health has also attributed to the factors concerning the growth. Researches have proved that the overall well-being of the body is linked with the oral health as a lot of diseases such as heart diseases, flu transmission, and low birth weight are associated with periodontal disease.

April, 2016 - Straumann acquired 51% residual ownership of Neodent (initially it had acquired 49% of the residual during June 2012) This deal augments Straumann's presence in the tooth replacement sector in the Latin American region and Brazil, which is the second largest market for implant dentistry.

Global Dental Consumables Market - Regional Analysis

As per the cost ranging differently in various countries, there is sometimes a lot of difference observed between countries for the cost of the materials alone, such as dental implants. Globally, the demand for dental consumables is ever increasing, due to the changing demographics trends, increasing dental treatments, and other factors. There is also an increase in the competition among the countries as well as within the countries as more and more dental care units want to become prominent and a first choice for the patient. The dental consumables market has also been affected due to the cosmetic dentistry market, which has shown a staggering growth in the recent years. Increasing awareness among the people for the well-being of oral health has also attributed to the factors concerning the growth. Researches have proved that the overall well-being of the body is linked with the oral health as a lot of diseases such as heart diseases, flu transmission, and low birth weight are associated with periodontal disease.

The Americas holds the largest market share and will continue to lead the marker during the given period due to high healthcare expenditures, the presence of global players, and high acceptance of new technologies within the region. Europe is the second largest market owing to the presence of effective healthcare structure and well-developed economies.

Asia Pacific region is expected to grow rapidly. China and India are likely to lead this market due to the fastest growing healthcare sector during the forecast period. The Middle East & Africa have the least market share. Additionally, factors such as lack of awareness, low healthcare expenditures will restrain the market during the corresponding period.

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Age-Related Macular Degeneration Market Swot Analysis, Major Key Players Revenue, Analysis And Forecasts To 2023

The growing awareness of AMD and the increasing geriatric population are anticipated to exhibit more opportunities for the growth of the age-related macular degeneration market. Moreover, as per the Community Eye Health Journal published in 2014 by the London School of Hygiene and Tropical Medicine, nearly 196 million people are estimated to suffer from age-related macular degeneration by 2020 worldwide.

The global market for age-related macular degenerations is expected to grow at a CAGR of approximately 7.3% during the forecast period.

Regionally, the Americas age-related macular degeneration market is segmented into two major regions, namely, North America and South America.

The Americas region holds the largest share of the global age-related macular degeneration market owing to the increasing cases of macular degeneration and growing health concerns. According to the Centers for Disease Control and Prevention (CDC), it was estimated that about 1.8 million people are suffering from age-related macular degenerations in America. Moreover, nearly 7.3 million people are at a significant risk of vision loss due to AMD.

The global age-related macular degeneration market is segmented by type, drug, route of administration, treatment, and end-user.

On the basis of type, the global age-related macular degeneration market is segmented into dry age-related macular degeneration and wet age-related macular degeneration.

On the basis of drug, the global age-related macular degeneration market is segmented into Eylea, Visudyne, Lucentis, Avastin, and others.
On the basis of route of administration, the global age-related macular degeneration market is segmented into intravenous, intravitreal, and others.
On the basis of treatment, the global age-related macular degeneration market is segmented into medications, devices, surgery, and others. The medication segment is further classified into anti-VEGF drugs, blood vessel growth inhibitors, vitamins, dietary supplements, and others. The devices segment is classified into corrective lenses, glasses, contact lenses, and others.
On the basis of end-user, the global age-related macular degeneration market is segmented into hospitals and diagnostic centers, clinics, academic research institutes, pharmaceutical and biotechnology companies, and others.

Some of the key players in the global age-related macular degeneration market are Novartis International AG (Switzerland), Bayer AG (Germany), Acucela Inc. (U.S.), Neurotech Pharmaceuticals Inc. (U.S.), Ophthotech Corporation (U.S.), GlaxoSmithKline Plc (U.S.), Alimera sciences Inc. (U.S.), StemCell Inc. (Canada), F. Hoffmann-La Roche Ltd. (Switzerland), Regeneron Pharmaceutical Inc. (U.S.), Allergan Plc (Ireland), Adverum Biotechnologies Inc. (U.S.), Gilead Sciences Inc. (U.S.), Iconic Therapeutics Inc. (U.S.), Lpath Inc. (U.S.), OHR Pharmaceutical Inc. (U.S.), Bausch + Lomb (U.S.), Opthea Limited (Canada), PanOptica, Inc. (U.S.), Pfizer Inc. (U.S.), Neurotech Pharmaceuticals, Inc. (U.S.), Promedior, Inc. (U.S.), QLT Inc. (Canada), Quark (U.S.), Resolvyx Pharmaceuticals Inc. (U.S.), RXi Pharmaceuticals Inc. (U.S.), Sagent Pharmaceuticals, Inc. (U.S.), Alcon Vision Care (U.S.), Santen Pharmaceutical Co., Ltd. (Japan), Sanwa Kagaku Kenkyusho (Japan), and others. 

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