Friday, 10 April 2020

Amyotrophic Lateral Sclerosis Market Covering Growth Inclinations & Development Strategies until 2023

Market Scenario
Market Research Future presents report by By Type (Familial ALS), by Treatment (Medication, Physical Therapy, Speech Therapy), by Diagnosis (Laboratory Tests, Imaging Tests), End-User (Hospitals, Specialty Centers) and Global forecast till 2023
ALS or Amyotrophic Lateral Sclerosis is a neurological ailment which affects the nerve cells in the spinal cord and the brain that controls the voluntary muscles’ activities. Some of the common symptoms of ALS include cramps, muscle weakness, respiratory problems, and fasciculation. This is a progressive neurological disease where gradually patients become dependent on physicians and caregivers increasingly. Often ALS results in respiratory failure as the patient loses the ability of controlling the muscles both in the diaphragm and the chest. Ultimately, it turns fatal.
Additional factors such as the inclination towards the sedentary lifestyle are driving the market growth and increasing the risk of developing ALS. Besides, the increasing geriatric population substantiates market growth, creating a demand for symptomatic and targeted treatment options.
The Global Amyotrophic Lateral Sclerosis Treatment Market size by valuation is expected to surpass USD 841.6 million by 2023, growing at approximately 7.89 % CAGR over the forecast period (2019-2023). In 2017, the market had a valuation of USD 526 million.
But the high cost of the treatment of ALS may hinder the market growth over the forecast period.
Segments                                                                                                                                            
The Global amyotrophic lateral sclerosis market has been segmented on the basis of type, treatment, and end-user.
By type, the market is segmented into sporadic and familial ALS. The sporadic ALS, also abbreviated as SALS, was the largest segment in 2017 and can dominate the market over the forecast period.
By treatment, the amyotrophic lateral sclerosis market has been segmented into medication, physical therapy, respiratory therapy, speech therapy, and others. Out of these, medication had the largest market in 2017.
By end-user, the ALS market has been segmented into hospitals, specialty centers, research & academic institutes, and others. Among these, the subsegment Hospital accounts for the largest segment.
Regional Analysis
By Regions, the global amyotrophic lateral sclerosis market is segmented into the Americas, Europe, Asia Pacific, and the Middle East and Africa.
The Americas is estimated to dominate the global ALS market owing to the increasing pool of awareness and the rising prevalence of hypertension. ALS remains a significant public health challenge in the US. Therefore, governments and private non-profit organizations are developing specific guidelines for the management and treatment of ALS. Public and private organizations are involved in strategic partnerships and collaborations in search for a better outcome in the research of amyotrophic lateral sclerosis treatment in the region.
The amyotrophic lateral sclerosis market in the European region stands at the second position in terms of the market size mainly due to the well-established healthcare sector. Several companies and research institutes are also establishing advanced facilities to research ALS.
Moreover, in recent years, there has been an increase in the adoption of sedentary lifestyles among people. Research shows that an increase in physical activities such as exercise helps in reducing the pain and thwarting some of the symptoms such as loss of motion in patients who have ALS.
Thus, the inclination towards the sedentary lifestyle increases the risk of developing ALS among the elderly population, thus creating a demand for symptomatic and targeted treatment options. The development of novel therapeutic approaches and advanced treatment options are likely to push the growth of the amyotrophic lateral sclerosis market during the forecast period.
Whereas, the ALS market in the Asia Pacific region is expected to grow rapidly due to the increasing prevalence of the disease and rapidly developing healthcare infrastructure. The increasing economy in the region is playing a vital role in the growth of the market. Furthermore, the increase in the setups of research and development centers also fuels the growth of the ALS market in the region.
Key Players                                                                                                         
  • Sun Pharmaceutical (India),
  • Mitsubishi Tanabe Pharma America (U.S.),
  • Biogen (U.S.),
  • Sanofi (France),
  • Mylan N.V. (U.S.),
  • Covis Pharma (Switzerland),
  • Ionis Pharmaceutical (U.S.),
  • ITF Pharma (U.S.),
  • Ascend Pharmaceuticals LLC (U.S.),
  • Apotex Inc. (Canada).
Feb 2019- Leading technology transfer company, BGN Technologies has lately disclosed about a new AI (artificial intelligence) platform to monitor and predict the development of neurodegenerative diseases in order to identify markers both for improved drug development and personalized patient care. This technology will focus on ALS at an initial stage and later on will be adapted to other neurodegenerative diseases namely Alzheimer’s and Parkinson’s. The latest technology will predict disease progression more accurately, a key component for clinical trials along with better identifying the interrelationships amid demographics and many other measurable factors that are identified through patient functionality and physical examinations. It will allow researchers in creating a system which insurers, HMOs, pharmaceutical companies, caregivers, physicians, and patients can use on mobile applications and desktop for monitoring and predicting ALS progression.

Rectovaginal Fistula Market 2020 Covers Global Industry Share, Size, Gross Margin, Future Trends, Demand, Business Insight by Leading Key Players Forecast till 2023

Global Rectovaginal Fistula Market Research Report: by Diagnosis (Physical Exam, Contrast Tests, Blue Dye Test, Computerized Tomography (CT) Scan) By Treatment (Medications, Surgery) By End User (Hospitals & Clinics, Diagnostic Centers) - Forecast Till 2023

Market Scenario
As per the Birth Injury Guide, estimates show that between 700 and 900 women die every year due to pregnancy or childbirth-related complications in United States.
Additionally, the growing research and development expenditure by the government as well as private sector is likely to contribute to the market growth. However, the high cost of surgery may restraint the market growth during the assessment period.  
Due to increasing focus on research and development in treatment of diseases, moreover increasing applications in cancer treatment are the factors responsible to boost the market growth during assessment period. Companies are using a trend of strategic alliance and acquisition to gain the market and minimize the competition in the market.
The Global Rectovaginal Fistula Market held a market value of USD 950 million in 2017 and is projected to grow at a CAGR of 5.4% over the forecast period. 
Key players
Some of the prominent players in the global rectovaginal fistula market are Cook Medical, Takeda Pharmaceutical Company, Johnson & Johnson Services Inc., Pfizer Inc., Allergan, AbbVie Inc, Novartis International AG, Bayer AG, Bristol-Myers Squibb, Boehringer Ingelheim GmbH, F. Hoffmann-La Roche, Eli Lilly and Company, GlaxoSmithKline plc, Sanofi S.A, and others
Segmentation
The global rectovaginal fistula market has been segmented into diagnosis, treatment, and end user.
Based on treatment, the market has been segmented into medications and surgery. Medications is further segmented into antibiotics and infliximab. Rectovaginal Fistula Surgery is further segmented into sewing an anal fistula plug or patch of biologic tissue into the fistula, using a tissue graft, repairing the anal sphincter muscles, performing a colostomy before repairing a fistula in complex or recurrent cases.
By diagnosis, the market has been segmented into physical exam, contrast tests, blue dye test, computerized tomography (CT) scan, magnetic resonance imaging (MRI), anorectal ultrasound, anorectal manometry, and others.
The rectovaginal fistula market, by end user, has been segmented into hospitals & clinics, diagnostic centres, academic institutions and research organizations, and others.
The global rectovaginal fistula market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The rectovaginal fistula market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.         
The European rectovaginal fistula market has been segmented into Western Europe and Eastern Europe. The Western Europe rectovaginal fistula market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.      
The rectovaginal fistula market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The rectovaginal fistula market in the Middle East & Africa has been segmented into the Middle East and Africa.       
Regional Market Summary
On regional basis, the Americas is anticipated to dominate the global rectovaginal fistula market owing to the growing R&D budgets by both government as well as commercial pharmaceutical and biotechnological companies and increasing adoption of advanced technologies in the region.  Europe is expected to hold the second largest position in the global rectovaginal fistula market owing to the presence of strong academic & research base and availability of funding for research in the European countries. Asia Pacific has served an opportunity for rectovaginal fistula market in this region due to increasing demand for the better treatment and devices and increasing prevalence of disease like cancer. The Middle East & Africa has the least share of the global rectovaginal fistula market. Moreover, the major market share of the region is expected to be held by the Middle East region owing to the increasing government initiatives for the healthcare sector.   

Global Pedicle Screw Systems Market 2020 – Investment Strategy, Outlook and Key Development till 2023

Market Scenario:
Pedicle screw system are the instruments that are used in spinal surgery to stop the pain caused by joints owing to disease. These screws are used in the lumbar spine for more complex anatomy such as the thoracic and thoracolumbar level. The pedicle screw allows stability in spinal arthrodesis and provide three column control over the spinal elements for improving deformation.
The Global Pedicle Screw Systems Market Size is accounted for USD 506.65 million in 2017 and expected to register ~ 6.3 % CAGR during the forecast period (2018–2023).
The rising prevalence of arthritis, increasing incidence of spinal cord injuries, aging population, and growing preference of minimally invasive surgeries are expected to drive the growth of the market. Moreover, rising R&D spending and aggressive strategies adopted by the top players such as new product launches are contributing to the growth of the market. For instance, in September 2018, Nvision Biomedical Technologies, LLC launched the pedicle screw system focus at North American Spine Society (NASS).
The high cost associated with pedicle screw systems, Sluggish product approval processes and strict regulatory frameworks may hamper the growth of the market during the assessment period.
Segmentation:
The Global Pedicle Screw Systems Market has been segmented on the basis of surgery type, product type, indication, application, and end user.
On the basis of surgery type, the market has been classified as open surgery and minimally invasive surgery. The market, by product type, has been segmented into polyaxial pedicle screw systems, monoaxial pedicle screw systems, and others. Based on indication, the market has been segmented into spinal degeneration, spinal trauma, spinal deformities, and others. The market, by application, has been segmented into thoracolumbar fusion and spinal cervical fusion. On the basis of end user, the market has been classified as hospitals and clinics, research organization and academic institute, and others. The polyaxial pedicle screw systems segment is expected to hold the largest market share of the pedicle screw systems market, by product type, during the forecast period. Also, minimally invasive surgery to register the highest CAGR in the global pedicle screw systems market during the forecast period.
The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The pedicle screw systems market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.
The European pedicle screw systems market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.
The pedicle screw systems market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The pedicle screw systems market in the Middle East & Africa has been segmented into the Middle East and Africa.
Regional Market Summary:
The Americas are likely to dominate the global pedicle screw systems market owing to the rising prevalence of spinal disorders, increasing geriatric population, and rising in FDA approved pedicle screws. According to the report published by Centers for Disease Control and Prevention (CDC), in 2016, 5.1% of men of 65 years and over are suffering with lumbar spine in United States. Also, 24.5% of women 65 years of age and over have lumbar spine in United States.
The European market is expected to be the second-largest pedicle screw systems market. The market growth in this region can be attributed to the government support for research & development and availability of funds for research.
Asia-Pacific is expected to be the fastest-growing pedicle screw systems market during the forecast period owing to the rising number of the orthopedic surgeries, rising investments in healthcare and expansions by market players in the region. Moreover, country such as India and China are considering fastest growing region due to the presence of huge patient population. Moreover, the government of these countries are open to adopt new technology, and best treatment option from a developed country. According to the report published by OMICS International, in 2017, around 500,000 to 600,000 spinal surgery had performed in China.
The market in the Middle East & Africa is expected to account for the smallest share of the global pedicle screw systems market due to an underdeveloped healthcare sector, lack of technical knowledge, and poor medical facilities.
Key Players:
Some of the key players in the global pedicle screw systems market are Alphatec Spine, Inc., Amedica Corporation, B. Braun Melsungen AG, Depuy Synthes, Globus Medical, Inc., K2M Group Holdings, Inc., Medtronic PLC, Nvision Biomedical Technologies, LLC., Orthofix International N.V., RTI Surgical, Inc., SeaSpine, Stryker Corporation, Zimmer Biomet Holdings, Inc.

Thursday, 9 April 2020

Digital 3D Printing Market 2020 Size, Business Research, Revenue, Growth Insights to 2025

Market Highlights
Digital 3D Printing Market is expected to have a market value of USD 5,214.8 Million till 2025. The digital 3D printing process involves a systematic evaluation and improvement of the products and services to achieve better quality. Digital 3D printing is related to those who manage the delivery of healthcare services. It seeks to improve the effectiveness of treatment and increase patient satisfaction with the service. It comprises of measurement, assessment, and improvement steps.
Segment Analysis
The Global Digital 3D Printing Market has been segmented based on Component, Material, Technology Application, and End User.
The market, based on component, has been bifurcated into system/device and software/services. The market, based on material, has been segregated into polymers, metal and alloy, ceramics, and others. The market based on technology has been bifurcated into stereolithography, deposition modeling, laser sintering, jetting technology, electron beam melting and others. The market, based on application, has been segregated into dental, prosthetics, orthopedics, medical components, tissue engineering, hearing aids, drug screening, and others. The dental segment has been further segmented into clear aligners and dental implants, dentures, crowns & bridges, and others. The dental implants segment is also classified into endosteal implants and sub-periosteal implants. The prosthetics segment has been further classified into prosthetic implants, hip disarticulation, lower limb/extremity componentry, finger splints, and others. The tissue engineering segment has been further bifurcated into bone and cartilage scaffolds, ligament and tendon scaffolds. The market, based on end-user, has been segregated into hospitals & surgical centers dental clinics & laboratories (offices), pharmaceutical & biotechnology companies and others.
Regional Analysis
The Global Digital 3D Printing Market, based on region, has been divided into the Americas, Europe, Asia-Pacific, and Middle East & Africa.
The Americas led the market and accounted for the largest share in 2018, owing to the presence of major market players, developed healthcare infrastructure, high awareness, and availability of advanced treatment options. For instance, in November 2015, a group of medical researchers from North Carolina’s Wake Forest University developed a method to print the 3D form of custom medications in the configuration of pills. These medical researchers at the university designed 3D printed pills with specific doses according to the medical and biological profile of an individual’s body weight, race, gender, and organ functions to improve the effectiveness and minimize the side-effects.
Europe accounts for the second-largest share in the global digital 3D printing market. The European Union (EU) estimated that around 850,000 medical errors were recorded in hospitalizations. Moreover, the rising pressure to reduce healthcare costs, rapidly increasing technological advancements, and better product and service availability in the region is expected to have a positive impact on the digital 3D printing market in Europe
Asia-Pacific is estimated to be the fastest-growing market during the forecast period due to the rising prevalence of chronic and acute diseases such as HIV, cancer, and diabetes, a large number of research organizations, and the development of new infrastructure to support the healthcare industry are expected to drive the market growth. Moreover, the increasing focus of big pharmaceutical companies to enter into this region is expected to drive the market growth.
The Middle East & Africa digital 3D printing market is segmented into two major regions, namely the Middle East and Africa. The Middle East and Africa have less economic developments and extremely low-income due to which the region accounts for the least market share but is expected to grow with the increasing cases of chronic diseases and demand for better treatments in countries.
Key Players
MRFR recognizes the following companies as the Key Players in the Global Digital 3D Printing Market— Stratasys Ltd (US), 3D Systems, Inc. (the US), EnvisionTEC (US), ExOne (US), General Electric (US), Formlabs (US), Materialise (Europe), Micron Dental (US), Carbon, Inc. (the US), Renishaw PLC (UK).

Global Hyperspectral Imaging System Market 2020 by manufacturers, Demand, application, and region 2025

Market Highlights
According to MRFR analysis, Global Hyperspectral Imaging System Market is expected to register a CAGR of 17.4% during the forecast period of 2019 to 2025 and held a value of USD 10,700 Million in 2018.
Hyperspectral imaging system has wide applications in areas such as art conservation, vegetation, water resource control, archaeology, food quality, forensic medicine, crime scene detection, and forensic medicine. HSI technology is mainly used by the defense sector, government agencies, and non-military application sectors such as agriculture and mineral.
The growth of the global hyperspectral imaging system market is boosted by various factors such as the growing industrial applications of hyperspectral imaging,  Technological advancements in electronics industry, such as sensor design, high spectral resolution, high spatial resolution, compact and lightweight devices, growing prevalence of cancer, and increasing awareness of innovative diagnostics methods.
Additionally, the introduction of innovative products in the market is expected to drive the growth of the market during the forecast period. For instance, In January 2020, Specim, Spectral Imaging Ltd. (Finland), launched Specim’s new AFX10, a compact hyperspectral camera for airborne use. Specim’s new AFX10 is easy to use and can be used to check water quality, estimating the fertilizing need in agriculture, identifying vegetation species, or studying wildlife population
However, the high cost associated with the use of hyperspectral imaging and scarcity of qualified professionals is likely to hamper the growth of the market during the forecast period.
Several market players currently dominate the global hyperspectral imaging system market. The key players are engaged in product launches and strategic collaborations to strengthen their market positions.
Regional Analysis
The Market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.
The Americas held the maximum share in the year 2018, owing to the presence of established key players in countries such as the US and Canada. The hyperspectral imaging system market in the Americas has further been categorized into North America and Latin America, with the North American market further divided into the US and Canada. The European hyperspectral imaging system market has been categorized as Western Europe and Eastern Europe. The Western European market has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The hyperspectral imaging system market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The hyperspectral imaging system market in this region is anticipated to be the fastest growing during the assessment period due to the rising mining activities, and blooming healthcare, agriculture, and biotechnology sector in the region. The hyperspectral imaging system market in the Middle East & Africa has been divided into the Middle East and Africa.
Segmentation
The Global Hyperspectral Imaging System Market has been segmented based on Product, Technology, and Application.
The market, based on product, has been divided into visible/near-infrared (VNIR), short-wave infrared (SWIR), mid-wave infrared (MWIR), long-wave infrared (LWIR). The Visible/Near-Infrared (VNIR) systems segment is likely to be the largest due to the high adoption of visible/near-infrared (VNIR) systems in various industries. The mid-wave infrared (MWIR) segment is predicted to be the fastest-growing due to increasing awareness about the rising adoption of MWIR systems in detecting volcanic vents, industrial gas leaks, or biomass burning events.
The global hyperspectral imaging system market has been segmented, based on the technology, into push broom, snapshot, and others. The push broom segment is anticipated to be the largest segment during the forecast period due to the rising popularity of these devices owing to the simplified illumination requirements, minimized illumination exposure, high spectral resolution, and heat load, and the shorter capturing time.
The applications segment of the global hyperspectral imaging system market surveillance, remote sensing, machine vision/optical, and medical diagnostics. The surveillance segment is likely to hold the maximum share during the forecast period due to the rising adoption of innovative technologies in the defense sector.
Key Players
Some of the Key Players in the Global Hyperspectral Imaging System Market are Headwall Photonics, Inc. (the US), Specim, Spectral Imaging Ltd. (Finland), Norsk Elektro Optikk as (NEO) (Norway), Resonon, Inc. (the US), Corning Incorporated(US), Telops (Canada), Applied Spectral Imaging(US), Bayspec, Inc.(the US), Surface Optics Corporation (US), Chemimage Corporation (US), Cubert GmbH (Germany), Raytheon (US), Galileo Group, Inc.(the US), Hypermed Imaging, Inc.(the US), Inno-Spec (Germany), Camlin Group Ltd. (UK), IMEC (Belgium), XIMEA GmbH (Germany), among others.

4D Printing in Healthcare Market By Key Vendors, Regions, Trends with Industry Study & Forecast to 2025

Market Overview
Global 4D Printing in Healthcare Market is expected to register a CAGR of 29.4% during the forecast period from 2019 to 2025 and expected to reach USD 30.4 Million by 2025.
In the past decade, there has been increasing use of 3D printing in the field of healthcare. The introduction of 4D printing and its shape-changing material property in the field of dentistry, implants, and prosthetics, among others will further enhance the 3D products used for these applications. The shape-changing property of the material used for 4D printing has been one of the major factors influencing the growth of the market.
Moreover, factors such as increasing research and development, rising investment by chemical companies. These chemical companies are keen on grabbing the opportunity for the development of smart materials in 4D printing, which in turn is directly enhancing the growth of the market.
Factors such as stringent regulatory policies for the approval of 4D printing medical devices market trends and limited skilled professionals have been major challenges for 4D printing in the healthcare market.  
Market Drivers
  • Increasing application of 4D printing in healthcare verticals such as dentistry, implants, and prosthetics.
    • The dental industry is one of the major applications of 4D printing. Clear aligners have been the most manufactured products via 3D printing in the dental industry.
    • Align technology, the leader in global clear aligners market, accounts for about 80% of the market. The company uses 3D Systems to produce over 1.6 million custom aligners per week.
    • Clear aligners can further be enhanced using 4D printing, as these products require shape altering properties according to the changing structure of the teeth on a weekly basis.
    • 4D printers are also used to manufacture various dental implants, including dental implants, dentures, crowns, & bridges, among others.
    • Increasing prevalence of dental diseases is further influencing the growth of the market. According to the MRFR research study in 2018, it was estimated that oral diseases affected more than 3.7 billion individuals that are around half of the world’s population.
  • Rising research and development
    • A research team from the US in March 2019, invented a new bio-ink that allows to print catalytically active live cells into several self-sustaining 3D geometries. These properties include tunable cell densities, fine filament thickness, and high catalytic productivity.
  • Growing investment by chemical companies
    • Various companies such as BASF Venture Capital GmbH and Evonik Venture Capital have invested in Chinese 3D printing companies
Market Challenges
  • Stringent regulatory policies for the approval of 4D printing medical devices
  • Limited skilled professionals
Segmentation
By Component
  • Software & Services: Software and services accounted for the major market share in 2018. 3D printers have already been installed in numerous healthcare facilities across the globe. However, these machines would require updated software and also various services for the manufacturing of 4D products.
  • Smart Material: Smart Material segment is expected to grow at the fastest growth rate due to continuous advancements for the materials in 4D printing. Investment by chemical companies for the development of smart material is further influencing the market growth.
By Technology
  • Fused Deposition Modeling: Accounted for the largest market share due to its wide choice of raw materials and cost-effective process
  • Direct Inkjet Cure: Expected to grow at the fastest growth rate majorly due to its dimensional accuracy, multi-material, and full-color printing properties
By Application
  • Dental: accounted for the largest market share owing to the use of 4D printing for manufacturing of wide dental products including clear aligners, implants, and dentures among others
  • Prosthetics: Expected to grow at the fastest growth rate due to increasing number of prosthetic procedures, accidental injuries, and sports injuries among others
By End-User
  • Hospitals & Surgical Centers: Accounted for the leading market share owing to the increasing number of hospital & surgical centers. According to a study published by the American Hospital Association, there were 5,534 registered hospitals in the US in 2017.
  • Dental Clinics & Laboratories (Offices): Use of 4D printing in dental clinics & laboratories, brings less complexity to existing procedures. Dental laboratories use 4D printing technologies that allow them to increase competitiveness and production, thus driving the growth of this segment.
By Region
  • Americas: The Americas spearheaded the market in 2018 and is likely to continue to command during the assessment period. This is attributed to the existence of a large number of medical device companies, increasing research and development, and the presence of a large number of noticeable players engaged in manufacturing of 4D printing devices and software
  • Europe: Reported for the second-largest share owing to increasing utilization of 3D & 4D printing in the field of healthcare. According to a study conducted in 2018, it was found that 65% of healthcare providers are implementing new printing technologies for medical products using custom made materials
  • Asia-Pacific: The highest growth rate is attributed to the growing investment by government bodies and private & public companies. For instance, in November 2018, BASF Venture Capital GmbH invested in Chinese 3D printing company Prismlab.
Key Development
  • In January 2019, Dentsply Sirona and Carbon announced a strategic collaboration to revolutionize digital denture materials. This strategic collaboration was announced to deliver denture materials for carbon digital 3D printing production solutions.
Key Players
  • Stratasys Ltd (US)
  • 3D Systems, Inc (US)
  • EnvisionTEC (Germany)
  • Poietis
  • (France) 
  • Organovo Holdings Inc. (US)
  • Materialise NV (Belgium)
  • Dassault Systèmes (France) 

Meningococcal Vaccines Market Global Analysis, Size, Share, Trends, And Forecast 2020 to 2023

Market Forecast
Meningococcal Vaccines Market has a demand for USD 172 Million doses in 2019. Further, the global estimated supply in 2019 is expected to be 203 Million doses.
Market Synopsis
Meningococcal meningitis is a bacterial infection caused by Neisseria meningitides. Disease incidence is high in West and Central Africa, where historically, serogroup A has been the most important cause of disease. More recently, meningitis outbreaks have gradually been associated with serogroup C, and to a lesser extent, serogroup W.
The meningococcal vaccines market is complex and diverse, with regional variations in serogroup distribution with substantial use outside routine immunization. The vaccine has approximately 29 marketed products targeting various combinations of the six serogroups (A, B, C, W, X, Y).
Market Influencer
Without an increase in production, the existing supply of conjugate MenACWY will be inadequate to meet the demand generated by the rising incidence of serogroups C and W, and the low availability of polysaccharide vaccines. Further, several multivalent, conjugate vaccines by Chinese and Indian manufacturers are in the pipeline, and, if prequalified they will be registered for use in many geographies. Moreover, if they are made available at acceptable prices it could increase global demand in Meningococcal Vaccines Market Trends.
Market Drivers
  • Rise in prevalence of the meningococcal disease
    • According to a document published by the U.S. Department of Health & Human Services, in 2017, there were approximately 350 cases of meningococcal disease reported. The disease has an incidence rate of 0.11 cases per 100,000 people in the United States. Any population group can be affected by the disease, with maximum prevalence in children younger than one-year-old and a second peak in adolescence. Adolescents and young adults, ranging from 16 to 23 years old, have the highest rates of meningococcal disease.
    • Further, increasing incidence of meningococcal disease in West and Central Africa regions is expected to drive the demand in the African region
  • Booming mortality of the meningococcal disease is leading to increasing demand for the vaccines
    • Approximately 10 to 15 in 100 people affected with meningococcal disease will face mortality. Further, up to 1 in 5 survivors will have long-term disabilities, such as loss of limb, deafness, and damage to the nervous system brain among others
  • Escalating positive results with the vaccines to boost the demand in the market
  • Growing research and development activities by prominent players in the industry
Market Restraints
  • Withdrawn production of polysaccharide vaccines has resulted in reduced country access, particularly for MICs in various regions. For example, Sanofi Pasteur, manufacturer of Menomune, declared in 2017 that the company is discontinuing the production of the vaccine. With the production of Menomune at hold, there were no polysaccharide vaccines approved for use in the United States

Meningococcal Vaccines Market Segmentation

By treatment, the market is segmented into Meningococcal Conjugate Vaccine, Polysaccharide, Subcapsular Vaccine.
Meningococcal A conjugate vaccine is significantly used in mass campaigns across affected regions like Africa. Since 2010, the vaccine has significantly decreased meningococcal disease incidence in the region. However, the demand for meningococcal A conjugate in the country remains uncertain given that national immunization program adoptions are based on the timing of Gavi funding decisions, the country’s readiness, and competing for vaccine introduction priorities.
In the polysaccharide segment, products such as MenACWY vaccines are in high demand. MenACWY vaccine is the most desirable combination, given its broader serotype coverage. MenACWY specifically has nine products that are available across polysaccharide and conjugate product segments, but conjugate products are suggested for use in routine immunization activities.
Moreover, the demand and supply of Subcap MenB vaccines is restricted to HICs and influenced by their acceptance into NIPs. Improved uptake of MenB vaccines is expected in the coming years but will likely be moderate and limited to high-income markets given the high price and competing interest of introducing MenACWY conjugate.
By end-user, the market is segmented into Hospital & Clinical, Research Laboratories, and Academic Institutes
Hospitals and clinics control the global market for meningococcal vaccines. The high growth of hospitals and clinics segment is attributed to the increasing application of vaccines in these healthcare facilities in conjunction with the growing prevalence and incidence of the meningococcal disease.
Moreover, research laboratories and academic institutes take up the second-largest share due to the boost in research and development in the market.
By region, the market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.
In the global market, China is expected to have the largest market share, which accounts for approximately 35% of the global demand. This is primarily due to polysaccharide products, which currently comprise 84% of China’s demand. Chinese suppliers presently focus only on meeting the demand of the domestic market, but some of the manufacturers have indicated interest in the global market as well. The dynamic product pipeline with several multivalent conjugate products in development may trigger changes in the future supply mix of the Chinese market. Moreover, in China, non-routine use (excluding campaigns) accounts for an estimated 9 million doses in 2019, which may help to sustain the huge market share in the forecast period.
UNICEF foresees all 26 African countries in the meningitis belt, which have completed mass campaigns in 2016. In 2015, seven countries in the region were introduced with meningococcal A conjugate vaccine through their mass campaigns and targeted a population of 233 million. Further, during 2016-2018, UNICEF introduced meningococcal A conjugate vaccine in 26 countries. Ghana was the first country to be introduced with the vaccine into its RI schedule in 2016. Also, four other countries including Mali, Niger, Nigeria, and Sudan introduced the vaccine into RI programs in 2016.
Key Developments in the Global Meningococcal Vaccines Market
  • In 2018, Pfizer granted FDA Breakthrough Therapy designation for Trumenba (Meningococcal Group B Vaccine). This vaccine plays a major role in the prevention of invasive meningococcal B disease in children aged 1 to 9 years
  • In 2018, GSK’s meningitis B vaccine Bexsero received Breakthrough Therapy designation from the US FDA for prevention of Invasive Meningococcal Disease for children 2-10 years of age
  • In 2015, Novartis Bexsero vaccine was approved by the FDA for the prevention of meningitis B. This vaccine is used as active immunization to prevent invasive meningococcal disease caused by serogroup B
Key Players
  • Baxter international
  • Pfizer Inc.
  • Sanofi S.A.
  • Novartis Pharmaceuticals Inc.
  • JN-International Medical Corporation
  • Serum Institute of India Ltd.
  • GlaxoSmithKline
  • BIO-MED
  • Others
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