Monday, 6 July 2020

Neuropathology Market 2020 Growing Trend And Demand In Healthcare Sector 2023

Market Synopsis of the Global Neuropathology Market
Neuropathology pertains to the aliment of nerves reculting in pain and numbness of the limbs and it is gaining prominence in this market. The increasing incidence of musculoskeletal conditions and technological advancements in medical diagnostic devices are some factors responsible for the growth of the global neuropathology market size.
The number of patients suffering from cerebrovascular disorders has increased rapidly and has reached an all-time high in the past few years. There has been a significant rise in the number of surgeries associated with the treatment of such disorders. As the neurosurgeries and spinal surgeries are very critical, continuous monitoring during the whole procedure proves to be beneficial as the information about the electrical signals in brain and the nerves can be obtained in real time.
The Global market of Neuropathology is expected to grow at a CAGR of approximately 6% during the forecast period 2019-2023.
Biopsies primarily consist of the skin. The recently developed neuropathy test, the epidermal nerve fiber density testing (ENFD) in which the nerve fibers of the skin is analysed by performing a  punch skin biopsy to identify small fiber neuropathies. This pathology test is becoming available in selected labs as well as a few universities; it replaces the traditional sural nerve biopsy test and is less invasive. It is used to identify painful small fiber neuropathies.
According to the Labor Force Survey (LFS), about 553,000 cases were registered for all work-related musculoskeletal disorder out of the total of 1,243,000 cases. Many healthcare professionals have started using these diagnostics techniques, especially in tertiary care centers and specialty hospitals which may promote and increase the demand for Neuropathology.
Key Players
Many new companies have jumped into the market in order to make the most out of the opportunities. Companies are implementing the strategies of mergers and acquisitions with other players.
  • ARUP Laboratories
  • Therapath LLC
  • Abbott Laboratories
  • Laboratory Corporation of America Holdings
  • Thermo Fisher Scientific Inc.
  • Hoffmann-La Roche Ltd.
  • Sakura Finetek USA Inc.
  • Danaher Corporation
  • Quest Diagnostics Incorporated
  • Agilent Technologies Inc.N
  • NeoGenomics Laboratories
Segmentation
The Neuropathology is segmented on the basis of diagnosis test, application, and end-users.
On the basis of diagnostic test, the market is segmented into the biopsy, body fluids, peripheral blood smears, tissue resections, and others 
The biopsy sub-segment is divided into Epidermal nerve fiber density testing (ENFD), Sural nerve biopsy test, bone-marrow biopsies, lymph-node biopsies and others
On the basis of product, the application market is segmented into cerebral hypoxia and stroke, perinatal disorders, CNS infections, demyelinative diseases, brain tumors, neurodegenerative diseases, inherited metabolic disorders, peripheral neuropathy, and myopathology
On the basis of end-user, the market is segmented into hospitals, clinics, research centers and others.
Regional Analysis
The Global Neuropathology Market consists of countries namely America, Europe, Asia Pacific, and the Middle East.
North America dominated the global neuropathology market owing to the increasing healthcare expenditure in North America since 2016. U.S. has some of the best hospitals in the world with state of the art infrastructure. Most of the hospitals and their neurology departments are well equipped with the equipment that is required for the working of the neuropathology techniques. Various organizations and private companies are engaged in the activities of spreading awareness about the benefits of the neuropathology test among common people through various educational and marketing ways. As a result, huge numbers of people are opting for the neuropathology tests as a point of care. The country has been developing number of academic courses to develop skilled personnel in the neuropathology field over the years. Hence the availability of the neuropathology specialists in North American countries is high.
Europe is the second largest market for neuropathology market. For Europe, the neuropathology market including the brain tumors market is regarded as a strong competitive market. European countries are now making efforts in promoting the benefits of the intraoperative neurophysiological monitoring services. Patient friendly healthcare and insurance policies are making a positive impact on the people taking medical assistance.
Asia Pacific is the fastest growing region over the forecast period. The healthcare spending in Asia increased due to an extension of state health care programs and the increasing affluence of the population. India, in specific, saw an expansion in spending due to a government resolution to enhance healthcare services.
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Diastematomyelia Market Report Growth, Size, Demand, Trends And Forecast 2023

Market Scenario
Diastematomyelia is a rare anomaly resulting in the vertical splitting of the spinal cord. Females are more susceptible to this disease than males. According to the World Health Organization (2015), 1 in 2000 people suffers from this disease. However, during the last few years, the prevalence rate is increasing continuously. Increasing number of patients suffering from the disease, rising geriatric population and rising government support for research & development have driven the growth of the market. Moreover, rising demand for the better treatment, and changing lifestyle habits have fuelled the growth of the market. However, the cost of the surgery is too high and is not affordable to the people in developing region. Thus, the high cost of treatment may restrain the market.
A number of diagnostic procedures are available in the market for the diagnosis of the diastematomyelia. Increasing healthcare expenditure and rising government support have supported the growth of the market. According to the Boston Children's Hospital, in 2015, 5% of children across the globe were suffering from sustain spinal cord injuries. Furthermore, rapid development in the imaging technology and continuous improvement in the medical services have fuelled the market growth. The cost associated with the surgeries is very high which is not affordable for the people in developing region. Thus, high cost of surgeries, and lack of the precise treatment may restrain the growth of the diastematomyelia market trends.
The Global Diastematomyelia Market is expected to grow at a CAGR of 8.3% during forecast period 2017-2023.
Key players
The major key players in the global diastematomyelia market: 3M (US), GlaxoSmithKline PLC (U.K), Pfizer Inc. (U.S.), Lineage Medical, Inc. (U.S.), Johnson & Johnson Services Inc. (U.S.), Bristol-Myers Squibb and Company (U.S.), B. Braun (Germany), Stryker Corporation (U.S.), Argon Medical Devices, Inc (the Netherlands), Cook Medical (U.S.)
SegmentationThe global diastematomyelia market is segmented on the basis of types, host, therapy, and end users.
On the basis of type, the market is segmented into dual dural sac (type 1), and single sac (type 2).
On the basis of host, the market is segmented into children and adults.
On the basis of therapy, the market is segmented into diagnosis & therapy. The diagnosis is further segmented into imaging techniques, and prenatal ultrasound. Imaging techniques are further categorised into Plain X-ray, CT, MRI and others. The therapy is further segmented into surgical intervention, scoliosis surgery, decompression (surgery), and others.
On the basis of end users, the market is segmented into hospital, clinics, ambulatory centers, and others.
Regional Analysis
Asia Pacific is the fastest growing region in the global diastematomyelia market owing to the presence of huge patient pool, rapidly developing economies, and increasing demand for the better treatment options. Majority of the market is driven by India and China owing to huge patient population.
The Americas dominates the global diastematomyelia market owing to large patient population. According to the Brain and Spinal Cord Injury Rehabilitation, in 2015, over 259,000 people in the U.S. were suffering from spinal cord injury. Increasing number of patients suffering from diastematomyelia and other spinal disease have driven the growth of the Americas diastematomyelia market. Additionally, high per capita income and increasing government support for research & development will fuelled the growth of the market. Diastematomyelia is considered as a rare diseases thus, government and other private companies are trying to create awareness among the people by conducting different seminars. Increasing awareness among people regarding the disease and well-developed technology will create opportunities for the development of the market.
Europe accounts for the second largest diastematomyelia market, which is followed by Asia Pacific. Availability of funds for research, huge geriatric population, and government support for research & development projected to drive the market in Europe. The U.K and Germany are the major contributors for the market.
Whereas, the Middle East & Africa owns the least share of the global diastematomyelia market due to the presence of poor economy, especially, in the Africa region. The market of this region is dominated by the Middle East due to a well-developed healthcare sector and huge healthcare expenditure. However, Africa region shows the fastest growth for the market.
Browse more details of Bone Density Test Market @  https://www.marketresearchfuture.com/reports/diastematomyelia-market-4794 
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Sunday, 5 July 2020

Anti-Fungal Agents Market Growth And Restrain Factors Analysis By 2022

Market Scenario:
Anti-fungal agents are used in the treatment of fungal infections. According to global action fund for fungal infection, globally, over 300 billion people of all ages suffer from a serious fungal infection every year.
The market drivers include rising prevalence of fungal infections, rising awareness, rise of immunity deficient population such as geriatrics, rise in exposure to infectious agents due to environmental factors such as pollution especially by particulates and agriculture residues and climatic conditions such as humidity and temperature, occupational hazards such as Jock itch, crowding etc. Growth of fungal infection due to off label use of broad spectrum antibiotics is a prime factor for the growing market for anti-fungal agents.
The market restraints include rising resistance to anti-fungal agents, use of air filters and air conditioning, excellent spectrum and efficacy of Azole class of anti-fungal agents, loss of patents and genericitization etc. Competition by generics is exceptionally strong and generics account for roughly 50% of total sales for anti-fungal agents. The market penetration is very easy as there has been loss of patents of block buster drugs. Over the counter drugs are an important reasons for the growth of anti-fungal agents market. The Middle East and Africa anti-fungal agents market is led by Azoles followed by Echinocandins. The Azole class is represented in the market by agents such as Noxafil, Vfend, and Diflucan.
Among the infections Dermatophytosis holds the majority share followed by candidiasis. The market leaders with considerable sales include fluconazole, terbinafine, voriconazole, itraconazole, and caspofungin.
Taking all factors into consideration, we expect the Middle East and Africa anti-fungal agents market to reach around $2.85 billion by 2022 from $2.32 billion in 2015, by the end of the forecast period at a CAGR of ~3.5%.
Study Objectives Middle East and Africa Anti-Fungal Agents Market:
  • To provide detail analysis of the market structure along with forecast for the next 6 years of the various segments and sub-segments of the Middle East and Africa anti-fungal agents market
  • To provide insights about factors affecting the market growth
  • To analyze the market based on various factors- price analysis, supply chain analysis, porters five force analysis etc.
  • To provide historical and forecast revenue of the market segments and sub-segments for Middle East and Africa anti-fungal agents market
  • To provide country level analysis of the market with respect to the current market size and future prospective
  • To provide country level analysis of the market for segments by product type, by construction material, by end users and other sub segments.
  • To provide overview of key players and their strategic profiling in the market, comprehensively analyzing their core competencies, and drawing a competitive landscape for the market
  • To track and analyze competitive developments such as joint ventures, strategic alliances, mergers and acquisitions, new product developments, and research and developments globally.
Intended Audience
  • Anti-fungal agents Manufacturers
  • Anti-fungal agents Suppliers
  • Private Research Laboratories
  • Research and Development (R&D) Companies
  • Market Research and Consulting Service Providers
  • Government Research Laboratories
  • Contract Manufacturing Organizations
Key Players for Middle East and Africa Anti-fungal agents Market:Some of the key players in this market are: Novartis AG, Pfizer, Inc., Sanofi-Aventis, Merck & Co., Inc., Enzon Pharmaceuticals, Inc., Bayer AG, Astellas Pharma, Inc., GlaxoSmithKline plc, Abbott, Sigma-Aldrich and others.
Segments:
Middle East and Africa anti-fungal agents market has been segmented on the basis of therapeutic indication which comprises into aspergillosis, dermatophytosis, candidiasis and others. On the basis of drug class; market is segmented into azoles, pyrimidines, echinocandins, polyenes, allylamines, and others. On the basis of route of administration; market is segmented into oral, local and others.
Regional Analysis of Middle East and Africa Anti-fungal agents Market:
UAE is the largest market for anti-fungal agents in entire Middle East and Africa anti-fungal agents Market closely followed by Egypt. The rest of Africa market is however the fastest growing with a huge unmet medical needs and peculiar climatic conditions that support growth of fungal infections.
The report for Middle East and Africa Anti-fungal agents Market of Market Research Future comprises extensive primary research along with the detail analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain the deeper insight of the market and industry performance. The report gives the clear picture of current market scenario which includes historical and projected market size in terms of value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information and strategies of the top key players in the industry. The report also gives a broad study of the different markets segments and regions.
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Global Cardiac Biomarkers Market Production, Capacity, Revenue, Price, Gross Margin Analysis And Forecast 2019-2025

Market Forecast
Cardiac Biomarkers Market is expected to cross USD 4236.02 Million by 2025 at a CAGR of 16.36%.
Cardiac biomarkers are protein molecules released into the bloodstream from heart muscle damaged by a blocked artery. These enzymes are measured to have an idea of how much muscle damage has been done. These biomarkers are specially used to help diagnosis, evaluate, and monitor patients with suspected acute coronary syndrome (ACS).
The increasing prevalence of cardiovascular diseases is expected to drive the growth of the global Cardiac Biomarkers Diagnostics Market share. Out of the 17 million premature deaths due to noncommunicable diseases in 2015, 82% were in low- and middle-income countries, and 37% were caused by cardiovascular diseases.
Market Synopsis
Tests for cardiac biomarkers are used to diagnose acute coronary syndrome (ACS) and cardiac ischemia, conditions associated with insufficient blood flow to the heart. These biomarkers are also helpful in determining a person's risk of these conditions and also helps monitor and manage someone with ACS and cardiac ischemia.
Troponin T and I, CK-MB, and myoglobins are most commonly in the evaluation of acute coronary syndrome. Out of this troponin T and I are the markers of choice for detecting the heart damage. However, other cardiac biomarkers are less specific for heart and may be elevated in other conditions like severe muscle injury, liver disease, and kidney disease.
The increasing incidence of cardiac diseases and related conditions are strongly motivating market players to introduce new efficient technologies in the market.
Market Influencers
High prevalence of cardiac disorders and increasing participation of market players are actively facilitating the growth of the cardiac biomarkers market. In September 2019, Abbott received FDA clearance for ARCHITECT STAT High Sensitivity Troponin-I blood test. This troponin diagnostic test will be used to detect heart attacks faster and more accurately than contemporary troponin tests.
Market Drivers
  • High prevalence of raised blood pressure: Raised blood pressure is the leading risk factor for cardiovascular disease. The prevalence of this troponin T blood pressure in adults aged 18 years and over was around 24.1% in men and 20.1% in women in 2015
  • Increasing adoption of outsourcing services
  • Growing technological advancements:
  • High spending by the pharmaceutical industry
  • The increasing popularity of POC cardiac testing kits
  • Increasing affordability for advanced cardiac treatments
Market Restraints
  • Chances of false diagnosis of myocardial infarction
  • High cost of the procedure
  • Presence of other efficient methods for the diagnosis of cardiovascular diseases
Cardiac Biomarkers Market Segmentation
By Type
  • Myocardial muscle Creatine Kinase (CK-MB): CK-MB has been the gold standard for detecting myocardial necrosis. After myocardial infarction, elevated CK-MB levels appear within 3- 8 hours, peaking within 9-30 hours and levels return to normal after 48- 72 hours
  • Troponins (T and I): The most important characteristic of this biomarker is its apparent absolute cardiac specificity. Among patients with acute coronary syndromes, troponins level has been reported to provide prognostic information useful for the early identification of patients with an elevated risk of unstable angina progressing to AMI and death
  • Myoglobin: Myoglobin is a low molecular weight heme protein is rapidly released into the circulation and is the first marker to exhibit raising levels after myocardial infarction
  • Brain Natriuretic Peptide (BNPs) or NT-proBNP: This biomarker is secreted primarily by the ventricular myocardium in response to wall stress. It is a very useful prognostic indicator in acute coronary syndrome
  • Ischemia Modified Albumin (IMA): This novel marker is produced when circulating serum albumin contacts ischemic heart tissues. IMA can be measured by the Albumin Cobalt Binding assay that is based on IMA's ability to bind to cobalt.
By Location of Testing
  • Point of Care Testing: Point of care testing expected to witness significant growth in the forecast period due to its increasing popularity
  • Laboratory Testing: Laboratory testing segment dominated the global cardiac biomarkers market. Increasing demand for cardiovascular disease diagnostics is boosting the revenue of this segment
By Application
  • Acute Coronary Syndrome: This segment holds the largest share owing to the increasing cases of this condition. It is a medical emergency that requires prompt diagnosis and care.
  • Congestive Heart Failure: It is a chronic progressive condition that affects the pumping power of your heart muscles
  • Myocardial Infarction: Approximately 1.5 million cases of myocardial infarction occur annually in the US region.
  • Atherosclerosis: Atherosclerosis is a disease in which plaque builds up inside your arteries. Cardiac troponins are used to assess the prognosis of patients presenting with atherosclerosis
By Region
  • Americas: The largest regional market. High prevalence of cardiac diseases is strongly expanding the US cardiac biomarkers market. As per the data suggested by the Centers for Disease Control and Prevention (CDC), around 610,000 people die of heart disease in the US every year. Also, coronary heart disease (CHD) is the most common type of heart disease, killing over 370,000 people annually.
  • Europe: Europe has some of the best healthcare services in the world, and rising participation of market players is strongly boosting the Europe cardiac biomarkers market. For instance, in October 2019, Novartis received FDA approval for Entresto for the treatment of symptomatic heart failure in pediatric patients aged one year and older.
  • Asia-Pacific: The fastest-growing regional market for Cardiac Biomarkers, Asia-Pacific, has the world’s largest population and fast-developing healthcare industry. Rising affordability for the advanced cardiac treatments and increasing disposable incomes are strongly impacting the growth of the Cardiac Biomarkers market in the region
  • Middle East & Africa: The Middle East & Africa has been primarily bifurcated into two regions—the Middle East and Africa. The presence of favorable government initiatives and recent healthcare reforms and developing healthcare infrastructure in the Middle East is expected to augment the market growth over the forecast period.
Key Players
  • Abbott Laboratories (US)
  • ACS Biomarker (The Netherlands)
  • BD (Becton, Dickinson and Company) (US)
  • bioMérieux SA (France)
  • Bio-Rad Laboratories, Inc. (US)
  • Danaher Corporation (US)
  • Hoffmann-La Roche Ltd (Switzerland)
  • Johnson and Johnson (US)
  • Quidel Corporation (US)
  • Randox Laboratories Limited (UK)
  • Siemens AG (Germany)
  • Thermo Fisher Scientific, Inc. (US)
  • Trivitron Healthcare Pvt. Ltd. (India)
  • Novartis (Switzerland)
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STD Testing Devices Market To Observe Strong Development By 2019

Market Forecast
STD Testing Devices Industry Market Share accounted for USD 70.29 Billion in 2018 and is expected to register a CAGR of 9.3% during the forecast period.
Market Synopsis
Sexually transmitted disease (STDs) is an infection caused due to some organisms. STDs can be transmitted from one person to another through sexual activity and intimate contact. The cases of sexually transmitted diseases keep climbing among 45 and older Americans. 82,938 cases of gonorrhea, syphilis, and chlamydia were reported among 45 and older Americans in the year 2016.
Market Influencer
The increasing prevalence of lifestyle diseases, rising geriatric population along with increasing awareness about sex-related diseases is influencing the market growth positively. The increasing number of product launches by key players in the market are likely to act as a promising factor for the increase in the near future.  For Instance, Quest Diagnostics launched three new sexually transmitted disease (STD) laboratory test packages that individuals can purchase online for some of the most prevalent STDs in the United States.
Market Drivers
  • Increase in prevalence of sex-related diseases
    • Every year, 376 million new cases of chlamydia, syphilis, gonorrhea, and trichomoniasis are reported globally. The total estimated direct cost of STIs annually in the U.S. is about USD 16 billion.
    • The most common STIs affecting a lot of people are Chlamydia, gonorrhea, and syphilis. Approximately 1.5 million cases of chlamydia were reported in 2015 in US alone which represents it to be the highest number of annual cases of any condition ever reported.
    • A total of 89,239 cases of gonorrhea were reported by 27 states of the European Union in 2017.
  • Increasing prevalence of lifestyle diseases
  • Rise in healthcare expenditure
  • Increasing geriatric population
  • Increasing mergers & acquisitions by prominent players in the market
    • For instance, in 2019, the US Food and Drug Administration (FDA) has cleared two tests "The Aptima Combo 2 Assay (Hologic Inc) and the Xpert CT/NG (Cepheid)" to detect Chlamydia trachomatis and Neisseria gonorrhoeae from throat and rectum samples.
  • Increasing awareness about STIs
Market Restraints
  • Lack of information about the symptoms and causes is hampering the growth of the market.
Segmentation
By Type
  • Laboratory Devices: It is expected to hold a larger share. Laboratory devices are the traditional methods of detecting STI and a large number of hospitals and clinics are expected to be using the laboratory devices.
  • Point of Care (POC) Devices: It is expected to be the fastest-growing segment as it is less time-consuming.
By End-User
  • Hospitals and Clinics: Hospitals and clinics segment dominates the global market for The positive growth of hospitals is attributed to factors such as high volume of STD tests performed in hospital-based laboratories across the globe and growing patient population.
  • Diagnostic Laboratories: Diagnostic Laboratories segment take up the second-largest share due to the rising number of diagnostic labs and the increasing patient population.
  • Research Laboratories and Institutes: segment is projected to be the fastest-growing segment over the assessment period. The research and development activities with respect to STD diagnostics and treatment have increased in last decade which has resulted in the growing demand for the devices and kits in the R&D facilities. Besides that, government funding for the research and development for effective treatment of STD has pushed the growth of this segment. The researchers from King's College London, have published a study in Nature Communications, according to them skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted infections (STIs).
By Region
  • Americas: It is the largest regional market owing to the factors such as large patient population, rise in prevalence of STIs, the availability of a wide variety of STD testing kits and surges in awareness about the causes of STIs and its treatments which are driving the growth of the market in this region.
    • According to the Centers for Disease Control and Prevention (CDC), more than 1300 cases of congenital syphilis, about 40% increase was reported in newborns during 2017-2018 in US. Similarly, a rise in 8487 new cases of women suffering from gonorrhea in US alone was reported during the year 2017-2018.
  • Europe: The key factors driving the market growth are the growing research and development support by government bodies for the healthcare sector, and the significant demand for STI testing is driving the growth of the STI testing devices market in Europe. Additionally, the rising initiatives by organizations are driving market growth. For Instance, EuroTEST initiative is a platform for information exchange and activities to improve early diagnosis and care of HIV, viral hepatitis, sexually transmitted infections, and tuberculosis.
  • Asia-Pacific: The Asia-Pacific region is anticipated to be the fastest-growing region in the global STI testing devices market. The rising patient population is driving the growth of the Asia-Pacific STI testing devices market. Additionally, increasing disposable income of the middle-class population, and improving healthcare infrastructure in emerging countries such as China and India are driving the market growth. However, unfavorable healthcare reforms may restrain the growth of the market to some extent.
  • Middle East & Africa: This region is the smallest market due to limited healthcare infrastructure and limited exposure to technological advancements.
Key Players
  • Abbott (US)
  • MedMira Inc. (Canada)
  • Qaigen Inc. (US)
  • Thermo Fisher Scientific (US)
  • Cepheid (Danaher Corporation) (US)
  • Hoffmann-La Roche AG (Switzerland)
  • Diasorin S.p.A (Italy)
  • Bio-Rad Laboratories, Inc. (US)
  • bioMeriuex (France)
  • Becton Dickinson and Company (US)
  • Hologic, Inc. (US)
  • GenePOC Inc. (Canada)
  • Meridian Bioscience (US)
  • OraSure Technologies (USTop of FormBottom of Form
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Invisible Orthodontics Market Size And Key Trends In Terms Of Volume And Value 2019

Market Forecast
Invisible Orthodontics Market growth reached a value of USD 2598.8 Million in 2018 and is expected to register a CAGR of 13.99% during the assessment period of 2019 to 2025.
Market Synopsis
With the evolving technological advancements in the dental field, the area of invisible orthodontics has gained extensive popularity. Bracket-less aligners, clear retainers, and invisible braces some of the examples of cutting-edge technologies which have been launched in recent years. The high incidence rate of dental diseases in the developing countries and the rising inclination towards the correction of teeth deformities are likely to fuel the growth of the invisible orthodontics market across the globe. For instance, in Brazil, approximately 1.4 million new orthodontic cases are reported every year. Therefore, the key players involved in the invisible orthodontics market are vigorously focusing on product approvals to expand their customer base and brace their position in the market.
Moreover, the field of dentistry is evolving day by day. Public, as well as private organizations, are focusing on catering to the changing needs of the customers in terms of providing demos, conducting campaigns and dental check-ups. Thus, the employment of such strategies will promise the growth of the invisible orthodontics substantially.
Market Influencer
Increasing support by regulatory authorities to the private and public companies, in terms of investment and product approvals, acts as a significant factor that contributes substantially to the growth of the invisible orthodontics market in the longer run.
Market Drivers
  • The increasing prevalence of dental diseases pushes the need for newer treatment options, indirectly fueling the growth of the invisible orthodontics market globally. For instance, 90% of Australians are experiencing tooth decay. Such a high occurrence rate pushes the patients to choose newer techniques and prevention methods, thus fueling the growth of the invisible orthodontics market.
  • Several established players, such as Align Technology, Inc., and Dentsply Sirona are actively involved in getting approvals from regulatory authorities for their products in the invisible orthodontics market. For instance, in March 2017, Align Technology, Inc. launched the Invisalign Teen with mandibular advancement, the first clear aligner solution for Class II correction in growing tween and teen patients. This elucidates the impression that such new approvals are sure to drive the growth of the invisible orthodontics market in the near future.
  • Partnerships and collaborations between key players and local players
  • Increasing technological improvements in the orthodontics industry
  • High investment in research and development for the development of efficient products
  • Growing awareness created by dental professionals and key players about the benefits of clear aligners among the patients
Market Restraints
  • Limitations of invisible orthodontic products. Products such as clear aligners require long treatment time, which is why some of the patients do not prefer these products. In addition, poor compliance of patients with the dentists’ instructions leads to other complications of using these aligners. This results in a decreased target audience which would be utilizing such products, indirectly curbing the growth of the market.
  • Grey market for dental distribution, in terms of illegal selling of products of low quality at a cheaper price
Segmentation
By Product Type
  • Clear Aligners: The clear aligners segment is further segmented into hard, medium, and soft. The hard aligners sub-segment held a market value of an approximate of USD 1,394 million in 2018. The clear aligners segment held the largest share in 2018 due to a number of product launches by key companies such as Align Technology, Inc., Danaher, and others.
  • Braces: This segment has been further divided into ceramic braces and lingual braces. The braces segment is expected to be the fastest-growing during the forecast period owing to the increased awareness about the benefits created by key companies by conducting campaigns and dental check-ups.
  • Clear Retainers: A clear retainer is molded perfectly to fit the new position of the teeth.
By Age Group
  • Below 15: Various companies are getting approvals of their products for adolescents. In March 2017, Align Technology, Inc. launched the Invisalign Teen clear aligner for teenagers. Such increasing initiatives by prominent players for the below 15 age group fuels the growth of this segment.
  • 16-35: People in this age group are highly affected by dental disorders, including bite issues, due to change in lifestyle in recent years. This huge patient pool acts as a perfect target audience for prominent players to develop their products. Thus, the16-35 segment is likely to be the fastest-growing segment during the forecast period.
  • Above 35: The increasing middle-aged and geriatric pool of population suffering from dental caries, weakening of gums, abnormal eruptions in the teeth, among others, are the key factors for the growth of the above 35 segment. The benefits of clear braces are becoming palpable as a growing number of adult patients are now pursuing dental care.
By Application
  • Excessive Spacing: Spacing may prevent the teeth from functioning properly and may also result in gum problems due to the lack of protection provided by the teeth. Therefore, companies are coming up with products for corrective measures and conducting workshops and campaigns to create awareness. Thus, this segment held a majority share in 2018.
  • Crowding: Crowding can either be the result of several other orthodontic problems, such as impacted teeth, and teeth that do not fall out naturally, among others.
  • Malocclusion: The market, based on malocclusion, has been segmented into open bite, deep bite, and crossbite. The malocclusion segment is expected to be the fastest-growing segment during the assessment period owing to the increasing number of patients suffering from crossbites and open bites. Moreover, companies such as Align Technology, Inc. has a portfolio of products which are primarily used for the treatment of malocclusion. Thus, such factors are fueling the growth of this segment.
  • Abnormal Eruptions: Abnormal eruption occurs when a tooth emerges through the gum in the wrong place.
  • Others: Other applications of invisible orthodontic products are for correcting overjets, underbites, and others.
By Region
  • Americas: Americas was the largest regional market in 2018, owing to the continuous activities such as acquisitions, and partnerships employed by prominent players in the major countries in America. For instance, in March 2018, Dentsply Sirona (US) announced the acquisition of OraMetrix (US), a leading industry provider of innovative 3D technology solutions in the field of orthodontics. With this, the company aims to strengthen its position in the American invisible orthodontics market.
  • Europe: The European region holds the second largest share as there is increasing support from regulatory authorities, as well as ample of distributors in the European countries. For instance, in December 2017, Institut Straumann AG (Switzerland) acquired Same Day Solutions (SDS), a dental distribution company in Portugal. This acquisition provided Straumann access to SDS’ customers, which added the sales power and has been helping in supporting the company’s operations in Portugal.
  • Asia-Pacific: The Asia-Pacific region is anticipated to be the fastest-growing region in the global invisible orthodontics market. Direct marketing initiatives by the manufacturers to consumers are playing a substantial role in increasing the target audience and thus increasing the market size in this region. Also, strategic joint ventures by key players are contributing to the growth of the market. For instance, in January 2019, Institut Straumann AG, a company based in Switzerland, entered into a strategic partnership with a Chinese company, Tianjin ZhengLi Technology Company Limited. With this, Institut Straumann AG obtained exclusive distribution rights in China for its clear aligners, and the company aims to leverage its strong marketing and distribution capabilities to penetrate the highly attractive Chinese market. Thus, such strategies are likely to fuel the growth of the Asia-Pacific invisible orthodontics market.
  • Middle East & Africa: The smallest market due to limited healthcare infrastructure. But, in the last few years, top companies operating in the invisible orthodontics market are involved in acquiring different local distributors in the Arabian region to gain foothold in the local markets.
Key Players
  • 3M (US)
  • Align Technology, Inc. (US)
  • Clarus Company (US)
  • ClearPath Healthcare Services (US)
  • Danaher Corporation (US)
  • Dentsply Sirona (US)
  • DynaFlex (US)
  • Henry Schein, Inc. (US)
  • Institut Straumann AG (Switzerland)
  • Ormco (US)
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Biosimulation Market Research Report 2019 Analysis And Forecast To 2025

According to MRFR analysis, Biosimulation Market is expected to register a CAGR of 15.9% during the forecast period of 2019 to 2025 and is likely to be valued at USD 4.4 Billion by 2025.  
Biosimulation is a tool used for the prediction of the outcomes of existing clinical trials associated with innovation and new drug development.
The growth of the Global Biosimulation Technology Market share is determined by numerous factors such as the growing adoption of biosimulation software by regulatory bodies, increasing healthcare expenditure, increasing use of pharmacokinetic & pharmacodynamic modeling in pre-clinical development and rising need to reduce the drug development costs. However, lack of standardization in biosimulation methodology and lack of trained professionals for monitoring biosimulation software are likely to hamper the growth of the global biosimulation market during the forecast period.  
Several market players currently dominate the Global Biosimulation Market. The key players are involved in product launches and strategic collaborations to strengthen their market positions. For instance, in September 2019, Certara Inc. launched version 8.2 of Phoenix, the most advanced and widely used validated software for PK, PD, and toxicokinetic modeling and simulation worldwide.
Regional Analysis
The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.
Americas has been segmented into North America and Latin America, with the North American market being divided into the US and Canada. The Americas is projected to hold the largest market share owing to the increasing R&D spending by pharmaceutical and biotechnology companies in the region and growing number of clinical trials & drug development practices.  
The European biosimulation market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The biosimulation market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Rising geriatric population and the presence of a large patient pool, are the key factors responsible for the fastest growth of the market in Asia-Pacific. The biosimulation market in the Middle East & Africa has been divided into the Middle East and Africa.
Segmentation
The Global Biosimulation Market has been segmented based on product, application, delivery model and end users.
The market, based on product, has been divided into software and services. The software segment is further segmented into PK/PD (pharmacokinetic/pharmacodynamic) modeling and simulation software, molecular modeling and simulation software, PBPK (physiologically based pharmacokinetic) modeling and simulation software, toxicity prediction software, trial design software, and others. The services segment is further segmented into in-house services and contract services. The software segment is likely to hold the maximum market share in the global biosimulation market owing to growing adoption of biosimulation software by pharmaceutical and research organizations and the increasing R&D investment for pharmaceutical research.
The global biosimulation market based on the application has been segregated into drug development, drug discovery, and others. The drug development segment is expected to hold a larger share of the market share owing to the rising adoption of biosimulation tool for the drug development process.
The delivery model segment of the market is divided into subscription models and ownership models.
Based on end users, the global biosimulation market has been segmented into pharmaceutical and biotechnology companies, contract research organizations, research institutes, regulatory authorities, and others. Rising adoption of inorganic growth strategies by different biosimulation service providers is likely to boost the adoption of biosimulation solutions in the pharmaceuticals and biotechnology companies.
Key Players
Some of the Key Players in the Global Biosimulation Market are Dassault Systèmes (France), Certara USA, Inc. (US), Simulation Plus (US), Schrödinger (US), Chemical Computing Group (Canada), Physiomics (UK), In Silico Biosciences (US), Advanced Chemistry Development, Inc. (Canada), Genedata AG (Switzerland), Nuventra Pharma (US), Evidera (US), Leadinvent Technologies (India), LeadScope, Inc. (US), Rosa (US) and INOSIM Software GmbH (Germany).
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