Monday, 17 August 2020

Pharmaceutical Analytical Testing Outsourcing Market Shares Analysis, Key Development Strategies And Forecasts Till 2023

 Increasing research and development investments is the key factor driving the pharmaceutical analytical testing outsourcing market. For instance, in 2018, Almac Group announced that it will invest USD 493,000 in additional nuclear magnetic resonance instrumentation at its headquarters in Craigavon, UK.

The Global Pharmaceutical Analytical Testing Outsourcing Market is slated to expand at a considerable rate and at a healthy 7.45% CAGR over the predicted years (2018-2023). Analytical testing plays a key role in the field of pharmaceutical development right from the initial stages of commercialization of the therapy or drug. It is a vital phase in drug manufacturing that includes identification, determination as well as purification of a single compound and/or mixture of compounds. This process also includes determining the chemical compounds’ structure along with helping in the characterization and synthesis of active pharmaceutical ingredients (APIs).

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Various other factors such as intense competition among pharmaceutical companies, increasing awareness about product quality, and safety and changing regulations for in vivo and in vitro tests are also expected to propel the growth of the market.

However, lack of awareness, and quality approvals and regulatory audits conducted in outsourcing laboratories can hinder the market growth over the forecast period.

Key players

Some of the key players in the global Pharmaceutical Analytical Testing Outsourcing market are SGS SA, Toxikon, Inc, Eurofins Scientific, Pace Analytical Services LLC, Intertek Group plc, Pharmaceutical Product Development, LLC, Exova Group plc, Boston Analytical, Charles River Laboratories International, Inc, West Pharmaceutical Services, Merck KGaA, WuXi AppTec, Source BioScience and others.

Segmentation

The Global market for pharmaceutical analytical testing outsourcing, by product type is segmented into raw materials, finished products and active pharmaceutical ingredients.

The market, by services, is segmented into bioanalytical testing, method development & validation, stability testing, and others. The bioanalytical testing segment is further classified as clinical and non-clinical. The method development & validation segment is further classified as extractable & leachable, impurity method, technical consulting and others. The stability testing is further classified as drug substance, stability indicating method validation, accelerated stability testing, photostability testing and others.

Based on end user, the market is segmented into pharmaceutical and biopharmaceutical companies, contract research organizations and others.

Regional Market Summary

The Americas dominated the global market for pharmaceutical analytical testing outsourcing. This can be attributed to the presence of major market players and increasing awareness about product quality, and safety within the region.

Europe stood second in 2017 owing to the increasing participation of market players and presence of developed economies like UK, Germany, France, and others within the region provides a driving force for the market to grow. In 2017, Eurofins Scientific acquired EAG Laboratories to enter into the dynamic and growing Materials and Engineering Sciences markets.

Asia Pacific was projected to be the fastest growing region in 2017. Factors such as growing research and development investment, increasing penetration of the market players within the region, and increasing government’s support for foreign investments drives the regional markets of the Asia Pacific region.

On the other hand, the Middle East and Africa held least share in the global pharmaceutical analytical testing outsourcing market due to the presence of poor economies and low per capita income, especially within the African region. The Middle Eastern region is estimated to be a major market for the Middle East and African region.

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Mortuary Refrigerator Market Leading Mortuary Refrigerator Market Key Developments Trends, Analysis And Forecasts Till 2023

 Mortuary Refrigerator Market Scenario:

Mortuary refrigerators are used to keep dead bodies as a solution to maintain hygiene requirements in hospitals. The key factors contributing for the market growth are growing number of cancer patient and cancer-related research, increasing organ transplant, and growing demands for automation in mortuary procedures. Also, the increasing geriatric population, is contributing to drive the market. According to the United Census Bureau, the global-female-geriatric population is estimated to reach 4,139 million by 2030 from 3,601 million in 2015. However, the minimal awareness about mortuary equipment and fluctuating prices of raw materials and substituting products for mortuary refrigerators hinders the market growth.

The global mortuary refrigerator market is expected to register a CAGR of 4.3% during the forecast period of 2018 to 2023.

Mortuary refrigerators are the largely used equipment in the whole mortuary equipment market. These refrigerators have available with several features such as temperature adjustable knob, multiple chambers. Mortuary refrigerators are available in both positive and negative temperature facility. The positive temperature refrigerator slows down the degradation process of dead bodies for a period of time, and the negative temperature mortuary refrigerators are used to storage the body by freezing it and prevent degradation for longer duration. The increase in technology and rising demand for automation in mortuary procedures is one of the reasons for the larger share of the market.

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Segmentation

The global mortuary refrigerator market is segmented on the basis of product type, application, application, end user, and region.

On the basis of product type, the market is segmented into positive temperature, negative temperature refrigerators.

By application, the market is categorised into corpses storage and forensic investigation. On the basis of end-user, the global mortuary refrigerator market is categorised into forensic labs, research and academics, funeral homes, hospitals and clinics, and others.

Regional Market Summary

The Americas dominates the global market for mortuary refrigerator owing to the increase in cancer and cancer-related research activities, increasing number of geriatric populations with health-related problems and presence of major market players within the region boosts the market growth. According to the Administration for Community Living in 2016, the number of older women within the region was estimated to be 26.7 million. Furthermore, the presence of developed economies and regulations by various authorities in healthcare sector within the region boosts the market growth.

In 2017, it was estimated that Europe stood second in the global mortuary refrigerator market. The increase in demand for mortuary refrigerator by forensic labs and hospitals to store the dead bodies for investigation increases the market growth. These equipment’s are also, used to store the entire body donated for medical research purpose, which are used in medical colleges to teach human anatomy.

Asia Pacific was the fastest growing region for the global mortuary refrigerator market in 2017. Factors such as increasing awareness about the advanced and innovative mortuary refrigerator, growing regulations and policies by various authorities regarding the hygiene in hospital drives the market growth.

On the other hand, the Middle East and Africa holds a least share in the global mortuary refrigerator market due to the lack of awareness about the advanced mortuary procedures and mortuary refrigerator hinders the market growth in this region.

Key Players

There are several Mortuary Refrigerator Market Manufacturers involved with advanced features and ease to use. However, the cost of mortuary refrigerators compare to other mortuary related products and presence of alternative products in the market are hindering the market growth.

Some of the key players in the global mortuary refrigerators market are LEEC (UK), Hygeco (Saint-Ouen, (UK)), Paragon scare Ltd. (London), Thalheimer Kühlung (UK), Barber Medical (UK), CEABIS (Italy), EIHF Isofroid (UK), EVERmed (Italy), and Fiocchetti and Funeralia (UK) and others.

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Global Leukemia Therapeutics Market Outlook, Key Financials, Segmental Revenue And Geographical Revenue Till 2023

 Leukemia Therapeutics Market Scenario:

 

The clinical condition an in which an increased number of abnormal leucocytes or generally called white blood cells of malignant characteristic is called leukemia. Frequent infections, fever with chills and fatigue are early signs of leukemia. Acute, chronic, lymphocytic, and myelogenous leukemias are classified under leukemia. Cancer statistics center of American Cancer Society estimates 61780 new cases of leukemia in 2019. Treatment for such a malicious disease requires intense therapeutic attention. Therefore, the need for accurate treatment in the rising population of leukemia patients is the major factor impelling the global leukemia therapeutics market growth. The traditional therapies involved in the treatment of leukemia are chemotherapy, biological therapy, targeted therapy, radiation therapy, and stem cell transplant. The complex pathology of leukemia demands advancements in medical infrastructure for treatment. Hence, letting the market key players immense opportunity to invest in research and development and bring forth innovation in the leukemia therapy. This generates a lead for clinical researchers to investigate better drug administration methods. Efforts which are being made to deliver more effective leukemia therapies is likely to trigger the leukemia therapeutics industry market growth.

However, on the flip side, the high cost of existing leukemia therapies and investment required for developing new therapies is curbing the expansion of leukemia therapeutics market share.

Global leukemia therapeutics market is expected to grow significantly over the forecast period. It is anticipated that the market held the value of USD 10.7 billion in 2017 and is projected to grow at a CAGR of 5.3% during the assessment period predicts Market Research Future (MRFR).

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Segmentation

The global leukemia therapeutics market has been segmented into type, applications, and region.

Based on applications, leukemia therapeutics market is segmented into acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia, and others. The acute lymphocytic leukemia segment is expected to account for the largest share segment of the market in 2017.

Based on type, leukemia therapeutics market is segmented into chemotherapy, biological therapy, targeted therapy, radiation therapy, and stem cell transplant. The chemotherapy segment is expected to account for the largest share segment of the market in 2017. Chemotherapy segment further sub segmented into alkylating agents, antimetabolites, antitumor antibiotics, and others.

Top Key Players

  • Eisai Co., Ltd (Japan)
  • Novartis AG (Switzerland)
  • Pfizer Inc. (US)
  • GlaxoSmithKline plc (UK)
  • Bristol-Myers Squibb Company (US)
  • Hoffmann-La Roche AG (Switzerland)
  • Sanofi S.A. (France)
  • Teva Pharmaceutical Industries Ltd (Israel)
  • Amgen Inc (US)
  • Takeda Pharmaceutical Company Ltd (Japan)

Regional Market Summary

Geographically, the Americas is anticipated to dominate the global leukemia therapeutics market owing to a well-established player, innovative therapies to drive the market for leukemia, increase prevalence of leukemia, and increasing older population.

Europe is expected to hold the second largest position in the global leukemia therapeutics market. The market growth in this region is attributed to increase prevalence of leukemia.

The leukemia therapeutics market in Asia-Pacific region consists of countries namely China, Japan, Republic of Korea, India, Australia and Rest of Asia-Pacific. The Asia-Pacific region is expected to be fastest growing region.

The Middle East & Africa has the least share of the leukemia therapeutics market.

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Worldwide Plasma Fractionation Market 2019 Synopsis With Leading Players, Industry Growth Factor Foresight By 2023

 Plasma Fractionation Market Scenario:

 

Increasing prevalence of immunodeficiency disorders and rising healthcare expenditure are also boosting the plasma fractionation market in the US region. According to the 2018 study published in the Allergy, Asthma & Clinical Immunology journal, the estimated overall prevalence of immunoglobulin A (IgA) deficiency in the US was approximately 1 in 300 to 1 in 500 persons.

Rising participation of market players is one of the key factors driving the plasma fractionation market. For instance, in 2018, Grifols acquired 24 plasma donation centers in the United States operated by Biotest Pharmaceuticals Corp. for USD 286 million. With this acquisition, Grifols now owns 249 plasma donation centres to increase its supply of plasma proteins used for therapeutic purposes.

 

In plasma fractionation process protein products are fractionated from human plasma for the prevention, and treatment of life-threatening conditions such as congenital deficiencies, immunologic disorders, and others.

 

Global Plasma Fractionation Market Growth expected to rise significantly over the forecast period. It is anticipated that the market held a valuation of USD 18073 million in 2017 and is projected to grow at a CAGR of 6.5% over the forecast period.

 

Various other factors such as increasing geriatric population, technological advancements, emerging markets in APAC and RoW, rising plasma collection, and increasing prevalence of respiratory and autoimmune disorders are also expected to propel the growth of the market.

However, the emergence of recombinant alternatives, high cost of advanced products, and unfavourable reimbursement policies can hamper the market growth over the forecast period.

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Segmentation

The global plasma fractionation market is segmented based on product, application, end user, and region.

The global market for plasma fractionation, by product is segmented into immunoglobulin, coagulation factor concentrates, albumin, protease inhibitors, and others. The immunoglobulin segment is further classified as intravenous immunoglobulin (IVIG), subcutaneous immunoglobulin (SCIG), and others. The coagulation factor concentrates segment is further classified as Factor VIII, Factor IX, Von Willebrand Factor, Prothrombin Complex Concentrate, Fibrinogen Concentrates, and Factor XIII.

Based on application, the market is segmented into immunology, neurology, hematology, critical care, pulmonology, rheumatology, hemato-oncology, and others.

Based on end user, the market is segmented into hospitals & clinics, clinical research laboratories, academic institutes, and others.

In the current scope of the study, the above-mentioned segments are covered into the four global regions, namely the Americas, Europe, Asia-Pacific and the Middle East & African region.

The plasma fractionation market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European plasma fractionation market has been segmented into Western Europe and Eastern Europe. Western Europe has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.  The plasma fractionation market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The plasma fractionation market in the Middle East & Africa has been segmented into the Middle East and Africa.

Regional Market Summary

The Americas dominated the global market for plasma fractionation owing to the presence of major market players and increasing prevalence of immunodeficiency disorders within the region. According to the 2018 study published in the Allergy, Asthma & Clinical Immunology journal, the estimated overall prevalence of immunoglobulin A (IgA) deficiency in the US was approximately 1 in 300 to 1 in 500 persons.

In 2017, it was estimated that Europe stood second in the global plasma fractionation market. This can be attributed to the increasing technological advancements, and rising R&D investments.

Asia Pacific was projected to be the fastest growing region in 2017. Increasing healthcare expenditure drives the regional markets of the Asia Pacific region. According to the Australian Institute of Health and Welfare, from 2015 to 2016, the total health expenditure was USD 181 billion. Out of this, USD 69 billion was spent on hospitals, which is a real increase of USD 2 billion from the previous year. During the same years, non-government sources spent USD 55.8 billion on health.

On the other hand, the Middle East and Africa held least share in the global plasma fractionation market due to inadequate economic development, especially within the African region.

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Atherectomy Devices Market Overview By Trends, Industry Top Manufactures, Size, Industry Growth Analysis & Forecast Till 2023

 Market Scenario

Atherectomy devices are built to either shave, cut, vaporize, laser or sand the plaques. The devices come with different indications. Different atherectomy devices have been invented for commercial use. The location of the plaque and type of blockage influence the choice of atherectomy device to be used. Some atherectomy devices are used only in the larger arteries on the upper portion of the knee, while other devices come with smaller catheters that are suitable for operating the arteries below the knee.

Atherectomy is a technique applied to eliminate atherosclerotic plaque from affected arteries. The plaques are in either peripheral or coronary arterial vasculature and may have distinct characteristics depending on the nature of the plaque. Atherectomy is used widely in cure of both peripheral and coronary arterial ailments. It is a minimally invasive endovascular surgery.

The worldwide Atherectomy devices market is likely to develop remarkably over the forecast period. It is projected that the global atherectomy devices market will register a CAGR of 6.12% over the forecast period of 2018–2023. In 2017, the estimated market value was around 1.09 billion.

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The growing rate of peripheral and coronary arterial diseases coupled with increasing demand for minimally invasive techniques is predicted to boost the growth of the atherectomy devices market. Minimally invasive surgical techniques deliver quicker recovery, quick procedural time, lesser risk of infections and complications. The worldwide atherectomy devices market is likely to witness noteable surge in demand due to exponential growth in the incidence of lifestyle-related ailments and elderly population.

Segmentation

The global atherectomy devices market is segmented on the basis of product type, application, and end user.

Based on application, the atherectomy devices market is segmented into cardiovascular, neurovascular, peripheral vascular, and others.

The atherectomy devices market, by product type is categorised into directional atherectomy systems, orbital atherectomy systems, photo-ablative (laser) atherectomy systems, rotational atherectomy systems, and others.

The directional atherectomy systems segment is expected to hold the largest share owing to the high treatment rate, whereas the photo-ablative (laser) atherectomy systems is expected to be the fastest growing segment owing to the growing preference by surgeons.

On the basis of end user, the market is segmented into hospitals, ambulatory surgery centers, and others.

On the basis of region, the global atherectomy devices market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas is sub-segmented into North America and Latin America. The North American region is further segmented into the US and Canada. The European region is divided into two, namely, Western Europe and Eastern Europe. Western Europe is further classified into Germany, Italy, France, the UK, Spain, and the rest of Western Europe. The Asia-Pacific region is sub-segmented into Japan, China, India, Australia, South Korea, and the rest of Asia-Pacific. The atherectomy devices market in the Middle East and Africa has been segmented into the Middle East and Africa.

Regional Market Summary

Asia-Pacific was projected to be the fastest growing region for the global atherectomy devices market. This owes to the technological advancements resulting in the development of cost-effective atherectomy devices leading to high acceptance rate for the devices in the Asia-Pacific region. The Middle East and Africa holds the least share in the global atherectomy devices market due to the presence of economically diverse countries, and less initiatives taken by the government.

It is projected that the Americas dominated the global atherectomy devices market owing to the growth of the market in the North American region. This is largely attributed to the factors such as increase in research funding, and growing awareness about the high-end atherectomy devices among medical professionals. Europe is expected to hold the second largest share in the atherectomy devices market owing to growing healthcare infrastructure. Additionally, various initiatives by public and private organizations is anticipated to boost the growth of the atherectomy devices market.

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World Dental Bone Graft Substitutes Market Top Key Players Shares, Revenue, Analysis And Forecasts To 2023

 Market Scenario:

The increasing incidence of oral diseases such as, dental caries and periodontal diseases, growing ageing population, and growing medical tourism in developing countries are expected to drive the growth of market. Dental tourism is increasing because dental patients mostly from a developed country are getting attracted towards other developing countries. Dental patients prefer to travel to the countries because these countries are providing cost effective and high-quality treatment. Mostly, the treatments in the dental tourism centers around the demand for dental implants. Countries like Hungary, India, South Korea and Turkey are increasingly gaining popularity in the area of dental tourism for their low cost and effective oral health treatment. On other hand, lack of proper reimbursement and stringent regulations can restrain the market growth over the assessment period. Moreover, increasing burden of oral diseases drive the growth of the market. According to Centers for Disease Control and Prevention (CDC), about 64.7 million Americans were suffered with periodontal disease.

Global dental bone graft substitutes market expected to lead industry growth significantly over the forecast period. It is anticipated that the market held value of USD 461.3 million in 2017 and is projected to grow at a CAGR of 9.4% over the forecast period.

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Global Dental Bone Graft Substitutes, by Key Players

  • Biohorizons Iph, Inc. (US)
  • Geistlich Pharma AG (Switzerland)
  • Dentsply Sirona (US)
  • Institut Straumann AG (Switzerland)
  • Medtronic Plc (US)
  • Zimmer Biomet Dental (US)
  • Dentium (South Korea)
  • LifeNet Health (US)
  • Orthogen, LLC (US)

 

Segmentation

The global dental bone graft substitutes market has been segmented into type, application, and end user.

Based on type, dental bone graft substitutes market is segmented into allograft, xenograft, alloplast, and others.

Based on application, dental bone graft substitutes market is segmented into ridge augmentation, sinus lift, socket preservation, periodontal defect, and implant bone regeneration.

Based on end user, dental bone graft substitutes market is segmented into dental clinics, hospitals, and others. The dental clinics segment is expected to account for the largest share segment of the market in 2017.

The dental bone graft substitutes market segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The dental bone graft substitutes market in the Americas further segmented into North America and South America, with the North American market divided into the US and Canada.

The European dental bone graft substitutes market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The dental bone graft substitutes market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The dental bone graft substitutes market in the Middle East & Africa segmented into the Middle East and Africa.

Regional Summary

Geographically, the Europe is expected to dominate the global dental bone graft substitutes market owing to the presence of well-established players, increasing incidence of oral diseases namely, dental caries and periodontal diseases, and growing ageing population. The Americas including US Dental Bone Graft Substitutes Market is expected to hold the second largest position in the global dental bone graft substitutes market. Asia-Pacific is expected to be the fastest growing market owing to growing medical tourism in developing countries and growing ageing population. Furthermore, the Middle East and Africa region is expected to account for the least market share in the global dental bone graft substitutes market.

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Global Antihypertensive Drugs Market Expected Tremendous Growth Till 2023

 According to a recent study report published by the Market Research Future, The global market of  Anti-Hypertensive Drugs was valued at $32.2 billion in 2015, and is projected to reach $ USD 41.2 billion by 2023. Thus the anti-hypertensive drugs market size is anticipated to observe a sluggish growth; at a CAGR of 2.73% during 2016 to 2022.

Anti-Hypertensive Drugs are used to treat hypertension (high blood pressure). Hypertension is a state of chronic elevated arterial blood pressure at or greater than 140/90 mm Hg for adults. Hypertension is one of the most powerful risk factors for cardiovascular morbidity and mortality. There exact cause of hypertension is unknown but is said that unhealthy, heady lifestyle and ageing mirror such disorders as “Hypertension”.

The major market driving factors for secondary hypertension are greater detection and early diagnosis. Rise in the prevalence diseases such as kidney problems, thyroid problems, adrenal gland tumours, heart ailments, chronic alcohol use etc. in which anti-hypertensive drugs are used; are some of the other factors driving the growth of the Anti-Hypertensive Drugs market. The constraints however are overwhelming and include patent expiries such as Actelion's Tracleer (2015), and United Therapeutic's Remodulin (2014). Other blockbuster’s such as Novartis's Diovan and Exforge, Sanofi Aventis's Avapro (2012) etc are also off-patent.

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Many antihypertensive drugs have their primary action on systemic vascular resistance. Some of these drugs produce vasodilation by interfering with sympathetic adrenergic vascular tone (sympatholytics) or by blocking the formation of angiotensin II or its vascular receptors. Other drugs are direct arterial dilators, and some are mixed arterial and venous dilators. Although less commonly used because of a high incidence of side effects, there are drugs that act on regions in the brain that control sympathetic autonomic outflow. By reducing sympathetic efferent activity, centrally acting drugs decrease arterial pressure by decreasing systemic vascular resistance and cardiac output.

Some antihypertensive drugs, most notably beta-blockers, depress heart rate and contractility (this decreases stroke volume) by blocking the influence of sympathetic nerves on the heart. Calcium-channel blockers, especially those that are more cardioselective, also reduce cardiac output by decreasing heart rate and contractility. Some calcium-channel blockers (most notably the dihydropyridines) are more selective for the systemic vasculature and therefore reduce systemic vascular resistance.

Segmentation

The Anti-Hypertensive Market can be segmented in to 4 key dynamics for the convenience of the report and enhanced understanding;

Segmentation By Pharmacological Class               : Comprises Diuretics, ACE Inhibitors, Calcium Channel Blockers, Adrenergic Blocker and other.

Segmentation By Hypertension Type                      : Comprises Systemic and Pulmonary Hypertension Drugs and other.

Segmentation By Disease Source                              : Comprises Primary and Secondary.

Segmentation By Regions                                            : Comprises Geographical regions - North America, Europe, APAC, including Anti-Hypertensive Drugs Market in India and Rest of the World.

Regional Analysis

The antihypertensive drugs market covers growth drivers in the following regions, namely Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA). The Americas accounted for a large market share owing to high prevalence of hypertension linked to cardiovascular and renal disorders. Drives by government and non-government organizations for creating awareness of the medical condition are likely to bolster the revenue of the antihypertensive drugs market in Americas.

The Europe region was the second-largest due to rise of cardiovascular diseases, unhealthy diets, and increase noticed in obesity levels of patients. According to the European Heart Network in 2017, heart diseases accounted for 3.9 million deaths. Germany, France, and the U.K. are expected to be the prime contributors to the antihypertensive drugs market in Europe.

The APAC region is projected to exhibit a robust pace owing to increased healthcare budget and rise in disposable income levels of patients. The setup of research and development centers to fast-track the commoditization of drugs for treating hypertension is likely to boost the APAC antihypertensive drugs market.

Key Players

Novartis AG, Daiichi Sankyo Company Limited, Acetelion Ltd, Boehringer Ingelheim, Sanofi S.A., Astra Zeneca plc, Ranbaxy Laboratories Limited, Inc., Takeda Pharmaceuticals Company Limited, Pfizer Inc. are some of the prominent players at the forefront of competition in the Global Market of Anti-Hypertensive Drugs and are profiled in MRFR Analysis.

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