Protein Engineering Market To Observe Strong Development By 2024

 Proteins, the building blocks of the body, are large biomolecules made up of amino acids. They perform various functions such as DNA replication, catalyzing metabolic reactions, transporting molecules from one location to another, and responding to stimuli. Furthermore, proteins also have a wide range of applications in the diagnosis of disease and treatment development. Protein engineering involves designing and constructing new proteins by modifying amino acid sequences to produce enzymes and desired properties and the synthesis of proteins with a particular structure. This technology helps us to understand the basics of how enzymes function and have evolved, and it is the key method of improving enzyme properties for applications in pharmaceuticals, green chemistry, and biofuels.

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The major objective of protein engineering is to produce biological compounds which include a synthetic peptide, storage protein, and synthetic drugs which will be superior to a normal one and create an enzyme which is superior in its properties to produce high-value chemicals in large quantities.

The global protein engineering market is driven by the increasing demand for new technologies having their application in healthcare and by the growth in research and development activities for improving health outcomes using novel technologies. Furthermore, the emergence of trends in protein identification and tracking and the increasing use of protein studies in research activities drive the growth of this market. However, there are various factors that may hinder the growth of the market such as expensive instruments used in protein engineering that require huge maintenance and lack of trained personnel.

Global market for protein engineering is expected to grow at a CAGR of approximately 6.2% during the forecast period 2017–2023.

Intended Audience

• Healthcare companies
• Contract Research Organizations (CROs)
• Research and Development (R&D) companies
• Academic medical institutes and universities

Segmentation:

The global protein engineering market is segmented to the basis of type, method, application, and end-users.

On the basis of type, the market is segmented into instrument, reagents, and services and software.

On the basis of method, the market is segmented into rational protein design and directed evolution.

On the basis of application, the market is segmented into food and detergent industries, environment applications, medical applications, biopolymer production, and nanobiotechnology.

On the basis of end-user, the market is segmented into academic research institutes, pharmaceuticals and biotechnology companies, and contract engineering organizations.

Regional Analysis

Globally, protein engineering market consists of four regions, namely, Americas, Europe, Asia Pacific, and the Middle East and Africa. North America is the largest market owing to the concentration of major market players and increase in a number of biotechnology and pharmaceutical companies. The U.S. is the largest market in North America followed by Canada. In the U.S., extensive protein engineering technologies and methods and availability of technologically-advanced devices and instruments for research also drive the growth of the market.

Europe is the second largest market for protein engineering which is majorly driven by the increasing demand for protein engineering methods and technologies and the overall growth of research and development sector in major countries such as Germany, the U.K., and France. Furthermore, the growth in funding for protein engineering and emphasis on drug discovery are other factors expected to drive the growth of the market during the review period.

Asia Pacific shows the fastest growth which is driven by the rising prevalence of lifestyle diseases such as heart diseases, diabetes, obesity, and others and need for new technologies with their application in healthcare.

The Middle East and Africa shows a steady but positive growth with an increase in the demand for new drugs and devices for diagnosis and the treatment of diseases and improvement in healthcare infrastructure.

Key Players

Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).

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Microfluidics Device Market Segmentation Detailed Study With Forecast Up To 2024

 A microfluidic device is well accepted technology and has several applications. The technology allows integration of many medical tests on a single chip. It has become an essential technology for integration, industrialization, miniaturization and parallelization of various tests in the fields of diagnostics, drug development and biological research. The technology also helps in reducing the side effects and improving the efficacy of treatment. New microfluidic methods are used for evaluating drugs and manipulating cells for the treatment of diseases related to heart and cancer.

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Globally, the market for microfluidic devices is gaining significant importance due to growing R&D investment in life sciences, pharmaceuticals, increasing point of care testing demand and An increase in point of care testing, as an effective method for delivery of treatment, has also led to increase in the demand for microfluidic devices in the global market

Some other factors driving the microfluidic devices market are rise in the commercial and analytical application of these devices and use of microfluidic products for miniaturization of chip.

Moreover some of the challenges faced by the market are adherence to stringent regulatory requirements to decelerate growth and geometrical and surface chemistry issues.

The use of microfluidic devices has been gaining importance into recent classification of research areas that target integration of laboratory protocols into miniaturized devices known as lab on chip.

This process includes many steps such as mixing, pre-treatment, reaction, separation, and pre-concentration. These processes help to reduce the cost and consume less reagent/sample, which is further helpful in various medical diagnosis with the help of blood drop. The miniaturization technique is expected to drive the microfluidic devices market, as this technique helps to reduce the overall cost of screening the compounds for cell biology problems by the pharmaceutical companies. Also the miniaturization technique helps in the reduction of analysis time and carry parallel assay in microfluidic devices, which is further expected to support the growth of this market.

Competitive Analysis:

Hoffmann-la Roche AG, Abbott laboratories, Siemens healthcare GMBH, Agilent technologies, Inc., Fluidigm corporation, bio-rad laboratories, ink, Cepheid, Raindance technologies, Inc., Dolomite centre, Micronit microfluidics, Johnson & Johnson, Becton, Dickinson and Company, These are some of the prominent players at the forefront of competition in the Global Microfluidic Devices Market.

Global Microfluidics Device Regional Analysis:

North America is the largest market for microfluidic devices, with factors such as growing old age population, increasing healthcare awareness, rising chronic and lifestyle diseases, technological developments for various home use applications and wider insurance infrastructure facilities driving the growth of microfluidic devices. With the rise in overall healthcare expenditure, the use of these devices has increased, since these devices provide accurate, reliable and quick results for early detection and prevention of diseases.

Due to its early introduction and wider applications in industries, use of microfluidic devices is high in North America as compared to other geographies. According to the European Federation of Pharmaceutical Industries and Associations, in 2014, the North American pharmaceutical market accounted for about 41.0% share of the global pharmaceutical market. High research and development expenditures in new drug lead to increase in the demand for various microfluidic devices for toxicity testing in the drug development process.

The European market for microfluidic devices is driven by increasing diagnostic requirements, due to rise in lifestyle associated diseases and increasing geriatric population. On the other hand, the increasing healthcare expenditure in the region has led to a shift in the focus of healthcare from hospitals to home, leading to increased use of microfluidic devices in the region.

According to the European Federation of Pharmaceutical Industries and Associations, R&D investment in Europe was about $40.2 billion, which lead to increased production of drugs in pipeline. The use of microfluidic devices is also expected to increase microreactors in drug synthesis and toxicity testing in drug development.

There are various regulatory issues related to microfluidic devices used for pharmaceutical research, point of care testing and clinical and veterinary diagnosis. The European Medical Devices Directives regulates the laws on performance and safety of the medical devices

In Asia, there has been an overall increase in the clinical outcomes and patient requirement, due to availability of specific and sensitive diagnostic tests, along with technologically advanced medical equipment and devices. At the back of this trend, Asia has become an attractive market for medical device companies.

Lately, China has become has come up as one of the fastest growing markets for microfluidics in Asia due to increased government funding and improving healthcare facilities.

Asian countries have different regulatory bodies for medical devices. In Japan, the Ministry of Health Labour and Welfare (MHLW) is responsible for the Japanese Pharmaceutical Affairs Law (JPAL) and regulates all medical devices manufactured or sold. Similarly in China, the State Food and Drug Administration (SFDA) is under the State Council, and is responsible for the supervision of the safety management of food, cosmetics and health food.

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Latest Study Offers Detailed Insights On Americas Cancer Immunotherapy Market 2023

 Cancer Immunotherapy is an advanced paradigm in cancer therapeutics. Cancer immunotherapy works by enhancing the patient’s immune system. This is generally accompanied by the administration of synthesized immune proteins. The most common therapeutic areas of cancer immunotherapy are inclusive of breast, prostate, lung cancer, and others. Increasing prevalence of the cancer is one of the major drivers for the market growth during the forecast period. Moreover, growing geriatric population and rising healthcare expenditure, increasing biotech and pharmaceutical sector boosts the market growth. However, lack of awareness and high cost for the services may restrain the market growth. 

The Americas cancer immunotherapy market is expected to grow at an approximate CAGR of 10.1% during the forecast period. 

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Segmentation

The Americas cancer immunotherapy market is segmented on the basis of cancer, therapeutics, and end users.

On the basis of the cancer, the market is segmented into lung cancer, prostate cancer, colorectal cancer, head & neck cancer, and others.

On the basis of the therapeutics, the market is segmented into monoclonal antibodies, immune checkpoint inhibitors, vaccines, non-specific cancer immunotherapies and adjuvants, and others.

On the basis of the end users, the market is segmented into hospitals & clinics, academic institutes, research organization, and others.

Regional Analysis

On regional basis the Americas is divided into North America and Latin America. North America is sub segmented into U.S. and Canada. North America commands for the largest market. The large share is also attributed due to the technologically advanced healthcare market, high prevalence of cancer, increasing development in cancer immunotherapy treatment and rising per capita healthcare expenditure. According to the National Cancer Institute in 2016, an estimated 1,685,210 new cases of cancer were diagnosed in the U.S. and approximately 595,690 people died due to cancer within the region. This is projected to drive the healthcare expenditure for cancer. By 2020, approximately USD 156 billion will invested on the cancer therapeutics and diagnostics.

On the other hand, Latin America is the fastest growing region due to the presence of the developing economies within the region, rising healthcare expenditure along with the huge patient population. Moreover, the presence of huge opportunities within the region fuels the market growth during the forecast period. 

Key Players

Some of the major player in the market are Amgen Inc. (U.S.), AstraZeneca (U.K), F. Hoffmann-La Roche Ltd. (Switzerland), Bayer AG (Germany), Bristol-Myers Squibb Company (U.S.), Eli Lilly and Company (U.S.), Merck & Co., Inc. (U.S.), Pfizer Inc. (U.S.), Novartis AG (Switzerland), and others.

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Orthopedic Biomaterial Market To Observe Strong Development By 2023

 Innovation is the organic strategy to gain the market. Many companies are operating in the market, however, the major companies dominated the major share in the market due to well-developed brand identity. Now-a-days, there is a significant increase in the number of the company offering orthopedic biomaterial.  Thus companies are adopting the new strategies to minimize the competition and increase the market. Some major companies are focusing on development of new and advanced products to gain the market share. Whereas, some are has used the technique of acquisition and collaboration to gain the market. There is also growing focus on customizing the material properties of bio-absorbable and composite materials with fillers such as bioactive ceramics.

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Some of the key players in orthopedic biomaterial market are:  Materion Corporation (US), Carpenter Technology Corporation (US), Ulbrich Stainless Steel & Special Metals, Inc. (US), CeramTec (Germany), Ceradyne (US), Heraeus Medical Components (US), Kyocera Corporation (Japan), Ticona GmbH (Germany), Purac Biomaterials (US), Acumed (US), Amedica Corporation (US), Johnson & Johnson (US), Osteotech, Inc. (US), Cam Bioceramics B.V. (Netherland), Landec Corporation. (US), and many more.

Latest Industry Updates

Being a competitive market, a number of different manufacturer are focusing on the product launch, and acquisition for the market development. Some of the latest development in the market are-

Feb 2016, TEKNIMED, a leader in biomaterial and at the forefront in medical solutions of the future, is present in various countries through a network of 250 distributors across the world, launched new biomaterials & surgical solutions in orthopaedics and spine surgery in India

Orchid Orthopedic Solutions is a worldwide leader of medical device outsourcing services from design and development through finished goods manufacturing. The company manufactures the new and advanced orthopedic biomaterials products to the customers. 

Global Orthopedic Biomaterial Market – Overview

Today, orthopedics is still in the search for reliable biomaterial for prosthesis. The biomaterial must have good longevity and other supporting properties in order to maintain low implant failure. The success of an implant depends on many factors. Biomaterial are the natural or synthetic materials origin used for the implants. Many medical implants like dental implants, heart valves and many more are prepared by biomaterials. Biomaterial has find its application in orthopedics. They are used in the various bones transplantation. As biomaterial not cause any immunogenic reaction with the body it makes it as a suitable material for this products. According to the Population Reference Bureau (2016), the number of Americans ages 65 and older was around 46 million which is expected to reach over 98 million by 2060. Increasing geriatric population across the globe has led to increase the incidents of diseases like osteoporosis and arthritis. Beside this increasing age simultaneously increases the possibility of bones problems and injury. Additionally, increasing government support, and increasing healthcare expenditure have fuelled the growth of the market during the forecasted period. Due to lack of time for exercise and poor diet increases the incident of different muscles and bone problems. Race to find the cost-effective alternatives has increases the competition between manufacturers and is the key challenge for them. High cost of the products may slow the growth of the market during the forecast period.

Regional Analysis

Regionally, the global orthopedic biomaterial market is segmented into: America, Europe, Asia Pacific, and the Middle East & Africa.

The Americas holds a significant market share of the global market owing to the presence of huge geriatric population and increasing prevalence of different bones diseases. Additionally, during last few years there is a significant increase in the number of accidents which has also helped in driving the growth of the market. Europe accounts for the second largest market in the globe due to a high patient population, high healthcare expenditure and string government support for research & development. Asia Pacific is expecting the fastest growth for the market owing to the presence of the huge opportunity for the growth of the market. The Middle East & Africa holds the least share in the market owing to the presence of the poor economic conditions Africa. Gulf nations such as Saudi Arabia and the UAE drive the Middle East & African market due to the well-developed healthcare sector and huge per capita income of the people.

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Sterilization Technology Market In Depth Study And Analysis Published, 2023

 Sterilization refers to a process that eliminates, or kills all pathogens using various technologies and methods that are applied for sterilization of equipment and medical devices in healthcare institutes. There is an increase in demand for sterilization technologies across the globe. Patient safety and the prevention of hospital-acquired infections being a significant concern have led to the rise in the demand for sterilization technologies in healthcare. The global sterilization technology market is expected to register a CAGR of 8.20% and is anticipated to reach USD 8,142.61 million by 2023. 

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Market Dynamics

Sterilization is the process that destroys or eliminates all forms of microbial life and is carried out in health-care facilities by physical or chemical methods. Sterilization technology includes processes such as gamma radiation, electron beam radiation, filtration, ionizing radiation, and thermal sterilization methods to destroy all microorganisms on the surface of an article or in a fluid to prevent disease transmission.

The sterilization technology market is driven by the increasing occurrences of hospital-acquired infections, increasing number of surgical procedures, growth in the pharmaceutical and biotechnology industries, and rising technological advancements in sterilization equipment. However, the stringent regulatory framework is expected to hamper the growth of the market during the forecast period.

Hospital-acquired infections are healthcare-associated infections that occur in patients under medical care who are not present or incubating at the time of admission. According to the World Health Organization, hundreds of millions of patients are affected by healthcare-associated infections (HAI) worldwide each year, leading to significant mortality and financial losses for health systems. Further, as per the European Centre for Disease Prevention and Control, approximately 30% of patients in Intensive Care Units (ICUs) are affected by at least one episode of healthcare-associated infection. Additionally, according to the World Health Organization (WHO), the prevalence of healthcare-associated infections varies between 5.7% and 19.1% in low- and middle-income countries. These increasing occurrences of HAIs have been leading to substantial financial losses for the overall healthcare system. This vast population affected with HAI are due to insufficient applications of standard and isolation precautions, whereas disinfection and sterilization ensure that medical and surgical instruments do not transmit infectious pathogens to patients. This considerable population affected with HAI and inversely rising need for sterilization are paving the way for a growth curve in the sterilization technology market

Segmentation

The global sterilization technology market has been segmented into type of sterilization, process, and end-user.

The global sterilization technology market based on the type of sterilization has been segmented into ethylene oxide, ionizing radiation (gamma radiation, electron beam radiation, and X-ray radiation), filtration, thermal sterilization, and others. Ethylene oxide takes accounted for 48.1% of market share, due to its high penetration, the strength of the radiation dose, and its exposure time. However, ionizing radiation is also likely to take up equal share due to significant health concerns related to the use of ethylene oxide.

The global sterilization technology, by the process, has been segregated into the chemical process (hydrogen peroxide, ozone, and chlorine dioxide), physicochemical (plasma and steam), synergetic processes (psoralens & UVA and low-temperature steam & formaldehyde), and physical processes (microwaves and pulsed light system). These processes use different compounds for sterilization of articles or surfaces.

Based on the end user, the market has been divided into the pharmaceutical industry, hospitals & clinics, and medical device manufacturers. Pharmaceutical industry dominates the global market for sterilization technology. It accounted for the largest market share of 38.4% and was valued at USD 1948.10 million in the year 2017 and is expected to reach USD 3163.60 million by 2023. Effective sterilization processes are vital within the pharmaceutical industries, and the safety of process units and final products depends on the highest quality of hygienic practice, as well as strict controls and regulatory compliance.

Key Players

The prominent players in the global sterilization technology market are Advanced Sterilization Products Services Inc., Atec Pharmatechnik GmbH, Sterile Technologies Inc., Steris PLC, 3M Company, Feldmeier Equipment Co., Donaldson Co. Inc., and Beta Star Life Science Equipment Inc.

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Nerve Stimulators Market 2020 Market Challenge, Driver, Trends & Forecast To 2023

 The Global Nerve Stimulators Market is expected to register a CAGR of 9.7% to reach USD 10,978.5 million till 2023. Nerve stimulation is a therapy that uses low-voltage electrical current for pain relief. The nerve stimulator used in nerve stimulation therapy is a bit like a heart pacemaker. In peripheral nerve and spinal cord stimulation, small pulse generator delivers electrical pulses to the nerves or the spinal cord. Nerve stimulator therapy has also proved as an efficient approach to get relief from neurological disorders. Among neurological disorders, nerve stimulation therapy is most commonly used for epilepsy and depression.

Rising incidence of chronic health problems, technological improvements, increasing geriatric population, and improved reimbursement policies in developed countries are expected to enhance the market growth. However, the lack of skilled or trained physicians and high cost of nerve stimulation therapy are projected to curb the growth of the market.

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Market Dynamics

Nerve stimulators have been gaining significance in recent years, owing to the increasing incidence of chronic health problems and increasing geriatric population. For instance, according to a study published in Pain Research and Management in 2017, the prevalence of chronic pain among Brazilian population was 39%, 31.7% in the French population, 48% in the UK, and 50% in the UK. Moreover, According to WHO, it is estimated that the world’s population aged 60 years and older will nearly double from 12% to 22% by 2050.

Segmentation

The global nerve stimulators market, by type, has been segmented into deep brain stimulator, a vagus nerve stimulator, and spinal cord stimulator. Based on applications, the nerve stimulators market has been classified as chronic pain, depression, dystonia, epilepsy, Parkinson’s disease, and others. Based on end user, the market has been classified as ambulatory surgical centers, hospital & clinics, trauma centers, and others.

Regional Analysis

The global nerve stimulators market, based on region, has been divided into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.

The Americas is expected to hold the largest share of the global nerve stimulators market. North America is expected to dominate the market, mainly due to the increasing geriatric population. According to a study published in the Drug and Alcohol Dependence journal in 2017, more than 100 million adult Americans are living with chronic pain. Chronic low back pain and headaches are the most commonly diagnosed conditions. It is also stated that conditions are more prevalent in women than men, i.e., 34.3% in women, and 26.7% in men in the US.

Europe is expected to account for the second-largest market share during the forecast period. The factors responsible for market growth in this region are the presence of huge geriatric population and high healthcare spending.

Asia-Pacific is estimated to be the fastest-growing region in the global market due to the presence of a vast neurological disorder’s patient population, presence of tremendous opportunities for the development of the market drive the growth of the nerve stimulators market in Asia-Pacific. According to a study published in Neurology India journal in 2014, it is found that out of a total population of India, around 30 million people were suffering from neurological disorders in India.

The nerve stimulators market in the Middle East & Africa is expected to grow due to the presence of a well-developed healthcare sector.

Key Players

The prominent players in the global nerve stimulators market are Boston Scientific Corporation, Medtronic, Cochlear Ltd, St Jude Medical, Inc., Cyberonics, Inc., Aleva Neurotherapeutics SA, and NeuroPace, Inc.

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CBCT Dental Imaging Market In Depth Study And Analysis Published, 2023

 The Global CBCT Dental Imaging Market is expected to register a CAGR of 9.8%and is anticipated to reach USD 817.5 Million by 2023. Dental Cone Beam Computed Tomography (CBCT) is a distinctive type of x-ray machine used in circumstances where regular dental or facial x-rays are not enough. This type of computed tomography scanner uses a special type of technology to produce three dimensional (3D) images of oral structures, soft tissues, nerve paths and bone in the craniofacial region in a single scan.

The growing use of CBCT in orthodontic diagnosis and treatment, increasing the use of CBCT imaging in cosmetic dentistry treatments, and rising adoption of CBCT by the healthcare professionals are the major drivers propelling market growth. However, the lack of awareness for the use of advanced technologies and risk of ionizing radiations for children and teens may hinder the growth of the market.

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Market Dynamics

Many institutes are using CBCT imaging technology is coupled with 3D clinical photography and accurate predictive altering for the precise diagnosis, planning, and treatment of orthodontics, and facial deformities and dental and facial implant surgeries. Institutes such as Inland Institute Oral & Maxillofacial Surgery are using full-craniofacial cone-beam CT (computed tomography) technology for highly accurate 3D radiographic images which will help in diagnosing, and planning and treating oral and maxillofacial surgery. The increasing use of CBCT for oral and maxillofacial surgery is driving the market for global CBCT dental imaging market. Additionally, increasing the use of CBCT in orthodontic diagnosis and treatment and increasing adoption of CBCT by healthcare professionals is likely to support market growth. On the other hand, lack of awareness for the use of advanced technologies and risk of ionizing radiations for children and teens are anticipated to hamper the market growth.

Segmentation

The global CBCT dental imaging market has been segmented into type of detector, application, and end user. Based on detectors, the dental CBCT imaging market has been classified as flat panel detectors and image intensifiers. The global CBCT dental imaging market, by application, has been ranked as dental implants, orthodontics, endodontic, and others. By end user, the market has been categorized as hospitals and dental clinics, academic and research institutes, and others. The hospitals and dental clinics segment accounted for a market value of USD 262 million in 2015.  

Key Players

The prominent players in the global CBCT dental imaging market are Carestream Health (US), Dentsply Sirona (US), FONA Dental, SRO (Slovakia), Gendex (US), Imaging Sciences International, LLC (US), J.MORITA MFG. CORP. (Japan), KaVo Dental GmbH (Germany), New Tom (Italy), Planmeca OY (Finland), Prexion (US), Sinclair Dental/Dentaire (Canada), SOREDEX (Finland), and Vatech Networks (South Korea)

Some of the key strategies followed by the players operating in the global CBCT dental imaging market were innovation, product development, acquisition, and expansion.

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