Turner Syndrome Market Growth And Restrain Factors Analysis By 2023

 Turner Syndrome is a rare chromosomal condition diagnosed in the female population. It occurs when one of the X chromosome is partially or completely missing. Women with condition are shorter than the average female and are unable to conceive due to early loss of the ovarian function. Webbed neck, a low hairline at the neck’s back, lymphedema are some of the common symptoms of the disease. Increasing prevalence of the disease and rising female population are the major factors that drives the market during the forecast period. According to the National Library of Medicine in 2017, about 1 in 2,500 new-born girls, worldwide, were affected with the Turner Syndrome, making it one of the causes of female-fetal-miscarriages and stillbirths. Moreover, according to the World Bank the female population increased from 3.60 billion in 2014 to 3.68 billion in 2016. Additionally, the increasing FDA approvals for the treatment of the diseases followed by growing biotechnology sector and increasing awareness of the women health is expected to fuel the market growth. However, high annual treatment cost followed by its related side effects like vomiting, carpal tunnel syndrome, insulin resistance/ high blood sugar, worsening of scoliosis, and others is one of the major restrains for the market growth. This along with low per capita healthcare expenditure and lack of the awareness within the low and middle income countries is projected to restrain the market growth during the forecast period.

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The market for global turner syndrome is estimated to grow at an approximate CAGR of 13.0% from 2017 to 2023.

Segmentation

The global turner syndrome market is segmented on the basis of diagnosis, treatment, and end user.

On the basis of the diagnosis, the market is categorised into physical examination, prenatal testing, karyotyping and others. The prenatal testing segment, by diagnosis, is sub-segmented into ultrasound test, amniocentesis, chorionic villus sampling, and others.

On the basis of the treatment, the market is segmented into human growth hormone therapy, oestrogen replacement therapy, progesterone replacement therapy, psychological therapy, and others.

On the basis of the end user, the market is segmented into hospitals & clinics, academic institutes, research organization, and others.

Regional Analysis

America dominates the global turner syndrome market owing to increasing adoption of new technologies and huge patient population. Additionally, rising healthcare expenditure, increasing female population followed by the presence of developed economies and healthcare sector within the region fuels the market growth.

Europe is the second largest market, in the global turner syndrome market. Rising research and development in healthcare sector, huge patient population, growing biotechnology sector are the major drivers for the market growth within the region. According to the International Trade Administration, the total turnover for the biotechnology sector in Germany reached from USD 3,280 million in 2015 to USD 3,410 million in 2016. It was also estimated that in 2016, the R&D expenditure for biotech sector was about USD 1,040 million

Asia Pacific region is the fastest growing market. Increasing awareness for women health, rising healthcare expenditures and growing healthcare sector are the major drivers for the market growth within the region during the forecast period. Moreover, the presence of the developing countries like the India and China within the region fuels the market growth. According to the Indian Brand Equity Foundation in 2017, the Indian healthcare sector was one of the fastest growing industries in India and is expected to advance at a CAGR of 22.87% from 2015-2020.

The Middle East & Africa has the least share in the global turner syndrome market.  The presence of poor economies and stringent government policies, especially in the African region restrains the market growth within the region. Majority of the market in the Middle & Africa region is held by the Middle East due to a well-developed healthcare sector and huge healthcare expenditure by the presence of the developed economies like Saudi Arabia, Kuwait, and Qatar within the region.

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Nonallergic Rhinitis Market Expected To Grow At High Cagr During Forecast Period 2020 – 2023

  Also known as vasomotor rhinitis, nonallergic rhinitis is a medical condition that causes chronic sneezing, and congestion. Although the symptoms of nonallergic rhinitis are similar to that of allergic rhinitis, it does not involve the immune system. This condition can be diagnosed with, physical examination, allergy test such as skin test, blood test, and imaging tests such as CT scan. Treatment includes use of nasal sprays, oral decongestants, and over-the-counter (OTC) drugs or prescription medications.

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Rising prevalence of nonallergic rhinitis, and increasing demand for diagnosis and treatment of nonallergic rhinitis are the major factors driving the growth of the market across the globe. Furthermore, increasing healthcare expenditure and overall growth of healthcare industry also influences the market growth. Splendid research in the field of immunology also boost the market. Additionally, increasing focus on the development of new medications for the treatment of nonallergic rhinitis, and increasing use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) also fuel the market growth. The growth of the market is restricted by increasing competition among key players in the market that act as a barrier of new entrants.

The global nonallergic rhinitis market is expected to grow at a CAGR of 5.3% during the forecast period.

Segments

The global nonallergic rhinitis market is segmented on the basis of diagnosis, treatment, and end user.

On the basis of diagnosis, market is categorized into physical examination, allergy testing, imaging test, and other segments. Allergy testing is further segmented into skin test and blood test. Imaging test is further segmented into nasal endoscopy, and computerized tomography (CT) Scan.

On the basis of treatment, the market is segmented into nasal sprays, NSAIDs and others.

Nasal sprays is further segmented into saline, corticosteroid, antihistamine, decongestants, and anti-drip anticholinergic.

On the basis of end user, the market is segmented into hospitals & clinics, research centers, and others.

Regional Analysis of the Global Nonallergic Rhinitis Market               

America holds the first position in the market for nonallergic rhinitis owing to the rising prevalence of nonallergic rhinitis in the U.S., and consequent increase in the demand for new diagnostic and treatment services. In Americas, North America is the largest market owing to the presence of key players in the industry. As per the Warren Alpert Medical School of Brown University, the prevalence of nonallergic rhinitis has been observed to be one-third that of allergic rhinitis, affecting ~7% of the U.S. population or ~22 million people. Additionally, rising awareness about morbidity due to nonallergic rhinitis and the presence of key players in the market also influence the growth of the market.

Europe is the second largest market for nonallergic rhinitis. In Europe, there is an increasing demand for nasal sprays, and extensive research and development activities by clinical research and academic institutes for chronic diseases treatment. Germany, and France are the largest contributors to the market growth owing to an increase in the number of market players manufacturing NSAIDs, and overall growth of healthcare industry.

The market in Asia Pacific is expected to grow at the fastest pace and is driven by an increasing number of patients suffering from nonallergic rhinitis and increasing awareness about the diagnosis and treatment. India, China, and Japan are major contributors to the growth of the market. This growth is attributed to an increasing demand for nasal sprays and OTC medicines and availability of highly qualified medical personnel dedicated to the research of chronic diseases.

The Middle East & Africa also show a steady rise in the market owing to low prevalence of nonallergic rhinitis and increasing awareness about allergic and nonallergic rhinitis treatment. In the Middle East & Africa, the Middle East captures the largest market share for availability of specialty medical services and increasing expenditure on healthcare

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3D Cell Culture Market 2020 - Opportunity, Driving Trends And Deep Study 2023

 3D cell culture is a technique in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Besides, the ability of 3D cell culture to provide more physiologically relevant information and more accurate data in vivo tests has led 3D cell culture systems to become acceptable in comparison to 2D Cell culture. Many factors drive the market of 3D cell culture across the world such as an advanced technique in organ and tissue regeneration, provide drug toxicology screening and many more.

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The global 3D cell culture market has been identified as one of the fastest growing industries, owing to the varying applications of 3D cell culture in biotech and pharmaceutical industry and rising prevalence of cancer worldwide, rising approval from government bodies, and growing awareness Increasing incidence of cancer and rising demand for organs transplantation due to increasing prevalence of organ failures has majorly influenced the growth of the market.

The global 3D cell culture market is expected to grow at a CAGR of 25.50% during the forecast period 2017–2023.

Segmentation                                                                                                                

The global 3D cell culture market is segmented on the basis of technique, product, application, and end-user. On the basic technique, it is segmented into Scaffolds Based 3D Cell Culture and Scaffold-Free 3D Cell Culture.  On the basis of the product, it is segmented into Consumables and Instruments. On the basis of the application, it is segmented into cancer research, stem cell research, drug discovery, Tissue Screening & Engineering, Regenerative Medicine and others. On the basis of the end users, it is segmented into Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Research & Academic Laboratories and others.

Key Findings

• The global 3D cell culture market was USD 725.15 million in 2016
• Consumables are the largest segment, by product which is projected to grow at a CAGR of 25.88% during the forecast period from 2017–2023
• Drug discovery is the largest segment, by application for the global 3D cell culture and expected to grow at a rate of CAGR 25.75% during the forecast period
• The Pharmaceutical & Biotechnology Companies segment and is expected grow with the CAGR of 26.13% for the forecast period.

Regional Analysis

Global 3D cell culture, on the basis of region, the market is divided into the Americas, Europe, Asia Pacific and the Middle East & Africa. The Americas accounted for the largest market share of for global 3D cell culture market. This large share is majorly attributed due to the presence of major manufacturers, high rate of cancer among the population, rising need for organ donation, and various others. Europe accounts for the second largest market share, whereas Asia Pacific is expected to grow at the fastest rate with 26.17% CAGR for the forecast period. With lots of opportunity and continuously growing economies, the region is expected to be the fastest growing segment. Factors such as recent healthcare developments, improving economies, high aging population, and increased healthcare spending are influencing the growth of the market. The Middle East & Africa with less economic developments and extremely low income accounted for the least market share in 2016 but is expected to grow in coming future.

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Cowden Syndrome Market Expected To Boost During 2020 To 2023

 Cowden syndrome is part of the PTEN hamartoma tumor syndrome. Cowden syndrome is characterized by a high risk of both benign and cancerous tumors of the breast, thyroid, endometrium, colorectal, kidney, and skin. The global Cowden syndrome market is expecting a healthy growth in the coming future. The global market is majorly driven by increasing Cowden syndrome patients across the globe. Additionally, increasing smoking population and rising consumption of alcohol have spurred the growth of the market. However, long time for approval and side effects of the treatment may hinder the growth of the market.

The global Cowden syndrome market is expected to grow at a CAGR of 6.7% during the forecast period 2017-2023.

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Key Players

Some of key the players in the market are Amgen, Inc. (U.S.), Eli Lilly and Company (U.S.), AstraZeneca Plc. (U.K.), Bristol-Myers Squibb Company (U.S.), Sanofi (France), AbbVie Inc. (U.S.), Spectrum Pharmaceuticals Inc. (U.S.), Novartis AG (Switzerland), GlaxoSmithKline Plc. (U.K.), Bayer AG (Germany), Takeda Pharmaceuticals (Japan), Pfizer, Inc. (U.S.), Merck & Co., Inc. (U.S.), F. Hoffmann-La Roche Ltd. (Switzerland), Janssen Biotech, Inc. (U.S.), Immunomedics (U.S.), and Oncomed Pharmaceuticals (U.S.)

Segmentation

The global Cowden syndrome market is segmented on the basis of site, treatment and end users.

On the basis of the site, the market is segmented into the breast, thyroid, endometrium (uterus), colorectal, kidney, skin (melanoma), and others.

On the basis of the treatment, the market is categorized into genetic testing, chemotherapy, surgery & radiation therapy, targeted therapy, hormone therapy, biologic therapy, and other. The chemotherapy is further segmented into anthracyclines, taxanes, antimetabolites, and alkylating agents. The targeted therapy is sub-segmented with monoclonal antibodies and tyrosine kinase inhibitors. Hormone therapy is further segmented into selective estrogen-receptor modulators (SERMs), aromatase inhibitors, and others.

On the basis of end users, the market is segmented into hospital & clinics, ambulatory care centers, and others.

Regional Analysis

The Americas dominate the global Cowden syndrome market owing to the increasing prevalence of people suffering from Cowden syndrome and cancer. Additionally, high healthcare expenditure, well-developed technology, and strong government support for research & development have fuelled the growth of the Americas Cowden syndrome market. Presence of the leading players and increasing availability of funds in this region are likely to support the growth in the coming future.

On the other hand, the Middle East & Africa hold the least share of the market due to limited availability of funds and availability of medical facilities, and poor political conditions in Africa. The Middle East holds the major share in the Middle East & Africa Cowden syndrome market. Kuwait, Qatar, Oman, and South Arabia holds the major share of the Middle East market. However, the African region is expecting a healthy growth due to the presence of a huge opportunity for the development of the market.

And The Europe accounts for the second largest Cowden syndrome market, which is followed by the Asia Pacific. Availability of the funds for research & development and strong government support have driven the market growth. The Asia Pacific is the fastest growing Cowden syndrome market owing to the increasing prevalence of cancer, rapidly developing the economy and increasing government support. India and China are expected to lead the market in this region.

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Protein Assays Market 2020 Share, Trend, Segmentation And Forecast To 2023

 Protein assays are utilized in life science research to detect the presence of protein in a sample. There are various assays available in the market differing from each other on the basis of sensitivity, principle and methodology. The macro factors such as sample size, amount, interfering agents and reproducibility are also responsible for its quantification. Protein assays rely mostly on color change i.e. colorimetric assay and use of standard protein such as immunoglobulin G (IgG) or bovine serum albumin (BSA). Protein quantification is the most important step before separation and analysis by electrophoresis or chromatography or any other immunochemical techniques.

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The use of protein assays for early diagnosis of diseases such as cancer and HIV may significantly reduce the morbidity and mortality of the disease. These assays are cost effective, facile and reproducible. Commonly used protein assay are Bradford, Lowry, BCA, and UV spectroscopic protein assays. Thus, use of assay in disease diagnosis, drug discovery and development encourages the biotechnology and pharmaceutical industry to invest in R&D, which fuels the demand of protein assays market.

Several new biomarker identification systems are launched by the key players which grants various opportunities for the global protein assay market. For instance, in June 2017, Gyros Protein Technologies AB launched a new version of its anti-drug antibody (ADA) solution for the immunogenicity market. This solution enables customers to automatically run the assays in a time-efficient manner using small volumes of patient samples and reagents, and shorten run-times.

According to a publication by Pharmaceuticals Research and Manufacturers of America (PhRMA), the organizations spent approximately $58.8 billion on R&D in 2015 accounted for the largest part of all the biopharmaceutical R&D spending in the U.S. However, high cost of multiplex assay hardware is limiting the growth of global protein assay market.

The global protein assays market is expected to grow at a CAGR of approximately 10.8% during the forecast period 2017-2023.

Segmentation

The protein assays is segmented on the basis of type, application, product, technology and end-users.

On the basis of type, the market is segmented into copper-ion-based assays, test strip-based assays, dye-binding assays, and others

On the basis of application, market is segmented into diagnosis, drug discovery, protein purification and others

On the basis of product market is segmented into reagents & kits, instruments and others

On the basis of technology, market is segmented into colorimetric-based protein assays, fluorescence-based protein assays, and absorbance-based protein assays

On the basis of end-user, the market is segmented into hospitals & diagnostic centers, academic institutes, pharmaceutical & biotechnology companies and others.

Regional Analysis

The global protein assays market consists of countries namely America, Europe, Asia Pacific, and the Middle East.

North America is projected to hold the largest share of the global protein assay market due to presence of superior research and development base, strong regional economics, and greater emphasis on disease prevention and wellness by governments.

The European protein assay market is expected to witness rapid growth owing to the high investment in various private and government funded research and development programs in the region and increased spending on pharmaceutical and biotechnology industry development.

Countries such as China, Japan, and India in Asia Pacific are also poised to be promising markets for protein assay in the near future. The healthcare expenditure in Asia increased due to an extension of state health care programs and the increasing affluence of the population. India is anticipated to witness an expansion in spending due to a government resolution to enhance healthcare services. Moreover, China and South Korea are striving to develop their biotechnology sector for diagnosis purpose. China’s efforts to develop its biotech sector has shown good results in sectors such as vaccines and biological products and the same can be expected in the protein assays industry. However, low research and development (R&D) yields, high infrastructure cost, stringent regulatory framework, and lack of trained resources are some of the restraints of the protein assay market.

The Middle East region is expected to grow at a faster rate due to the factors such as the extensive development of health care infrastructure and growing emphasis on research and development in the health care sector.

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Hypotonia Market Trends And Drivers Analysis 2020 To 2023

 Hypotonia is also known as floppy baby syndrome, or weakness of muscles and lack of muscle tone.   There are two main types of hypotonia – Acquired hypotonia in which hypotonia develops after birth as the result of an underlying medical condition, injury or trauma; and congenital hypotonia in which hypotonia is present at birth. Hypotonia is a symptom rather than a condition. Major causes of hypotonia can either be neurological or non-neurological.

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Hypotonia is characterized with diminished muscle tone. The infant or child with hypotonic cerebral palsy appears floppy like a rag doll, hence the name. Hypotonic cerebral palsy is the result of an injury or malformation at an earlier brain developmental stage than that which causes spastic or choreoathetoid cerebral palsy. There are various causes of cerebral palsy which includes brain injury or brain malformation that occurs while the brain is developing i.e before, during, or after birth. As a result of the brain damage, during brain development, a child’s muscle control, muscle coordination, muscle tone, reflex, posture and balance can be affected.

Neurological problems present at birth which affect a child’s movement and co-ordination of brain and spinal cord injury including bleeding in the brain.

According to the World Health Organization estimates, neurological disorders are responsible for 4.5%-11% of all illnesses in the world including low or high income economies. This is far higher as compared to the number of respiratory ailments, gastrointestinal disorders, or cancers, and the burden is expected to increase further over the coming years.

However, limited availability of facilities and higher treatment cost may hamper the market growth during the forecast period.

The global hypotonia market is expected to grow at a CAGR of ~5.8% during the forecast period 2017-2023. 

Intended Audience

• Pharmaceutical and Biotechnological Companies
• Research and Development (R&D) Companies
• Ambulatory Care Centers
• Academic Institutes and Universities
• Market Research and Consulting Service Providers
• Potential Investors 

Segmentations

The global hypotonia market is segmented on the basis of types, diagnosis, treatment, and end user.

On the basis of the type, it is segmented into acquired hypotonia and congenital hypotonia.  

On the basis of diagnosis it is segmented into physical examination, blood tests, muscle biopsy, assessment of cerebrospinal fluid, computerized tomography or CT scan or magnetic resonance imaging (MRI) scan, electroencephalogram, electromyography, metabolic panel tests, assessment of thyroid hormone, nerve conduction velocity, genetic testing, and others.

On the basis of treatment, it is segmented into physiotherapy, occupational therapy, speech and language therapy, drugs, and others. Drugs is further segmented into neostigmine, physostigmine, and others.

On the basis of the end user, it is segmented into hospitals & clinics, research laboratories and others.

Regional Analysis

The Americas dominate the global hypotonia market owing to well-developed technology, increasing patient population, high health care spending, and increasing government support for research & development. Furthermore, increased R&D activities and the concentration of major companies have fuelled the growth of the market in this region.

Europe holds second position in the global hypotonia market owing to government support for research & development and availability of funds for research. This is expected to continue to drive the European market over the forecasted period. For instance, developed economies of the region such countries such as Germany and France are increasing investment in the healthcare domain and are focusing more on hospital infrastructure.    

Asia Pacific is the fastest growing hypotonia market owing to the presence of rapidly developing healthcare technology, huge patient population, and high healthcare expenditure. Moreover, increasing patient population in countries like India and South Korea are likely to emerge as the fastest growing market across the globe. Furthermore, increasing demand for quality devices in the healthcare is projected to lead the use of advanced equipment, which, in turn, may increase the market growth in this region.

On the other hand, the Middle East & Africa holds the least share of the market owing to less availability of funds, limited medical facilities, and deprived political conditions in Africa.

Key Players

Some of key the players in the market are LivaNova PLC (U.K), EnteroMedics Inc. (U.S.), ElectroCore Medical LLC (U.S.), Boston Scientific Corporation (U.S.), Cyberonics, Inc. (U.S.), NeuroMetrix, Inc.(U.S.), ImThera Medical (U.S.), and Inspire Medical Systems, Inc.(U.S.), and others.

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Asia Pacific Pregnancy & Ovulation Market Value Share, Supply Demand, Share And Value Chain analysis 2023

 The Asia Pacific pregnancy and ovulation testing market is anticipated to touch USD 298.68 billion by 2023, as per an insightful report by Market Research Future (MRFR). It is expected to exhibit a 6.1% CAGR during the assessment period (2018-2023). The increasing acceptance of home testing kits to check the possibility of pregnancy is projected to spur market demand during the forecast period.

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Pregnancy tests are kits capable of detecting hormones such as human chorionic gonadotropin (hCG) in urine. Ovulation tests, on the other hand, are capable of detecting an uptick in luteinizing hormone (LH) to decide the optimal time for conceiving children. Availability of ovulation monitors on e-commerce websites, awareness of fertility tests, and awareness of these tests made possible by various promotional marketing activities by major brands are likely to lead to an uptick in market demand over the forecast period.

Digitization of results to provide privacy to consumers has been made possible owing to pervasiveness of smartphones. For instance, the FIRST RESPONSE Pregnancy PRO Digital Test & App Access by Church & Dwight Co., sends accurate results to the consumer’s smartphone. But high costs of ovulation tests can act as a market deterrent.

Report Overview

This report allows the user to gain a deeper understanding of the ongoing events and trends in the Asia Pacific (APAC) market for pregnancy and ovulation testing. By correlating the historical data with key market dynamics, our analysts can make highly accurate projections in the report. MRFR’s report includes a thorough segmental analysis of the APAC market segmented by type, mode of purchase, end-user, and region with astute insights. This report has been prepared to assist industry participants in making informed decisions on growth strategies and operation management. Users will come across drivers, trends, opportunities, and restraints which are likely to influence the growth of the market during the assessment period.

Segment Overview

By type, the Asia Pacific pregnancy and ovulation testing market has been segmented into pregnancy and ovulation testing. The pregnancy testing segment is sub-segmented into blood-based and urine-based testing. This segment is touted to garner above average demand owing to advances in pregnancy testing kits and alarming cases of polycystic ovary syndrome (PCOS). Similarly, the ovulation testing segment is sub-segmented into fertility monitors and ovulation prediction kits.

By mode of purchase, the market is segmented into prescription and non-prescription testing/over-the-counter (OTC) testing.  The non-prescription testing mode of purchase is projected to experience remarkable growth thanks to preference for home pregnancy tests and privacy concerns among women.

By end-user, the market is segmented into fertility centers, hospitals and clinics, and others. The hospitals and clinics segment is likely to register a 5.8% CAGR during the forecast period owing to their propensity to handle large patient volumes.

The segments and sub-segments covered in the report are analyzed under six major regions – India, China, Japan, Republic of Korea, Australia, and Rest of Asia Pacific, with respective country-level market sizing. For the scope of research, the standard definition of the product/service “pregnancy and ovulation testing” is included in the report. The report discusses and interprets the current and future opportunities of the industry by delivering an unbiased growth assessment.

Players Covered

Gregory Pharmaceutical Holdings, Inc., Proctor & Gamble, TaiDoc Technology & Corporation, Mankind Pharma Ltd., Geratherm Medical AG, Fairhaven Health, LLC, Quidel Corporation, Piramal Enterprises Ltd., Cadila Healthcare Limited, and Church & Dwight Co., Inc., are noteworthy players in the Asia Pacific pregnancy and ovulation testing market.

The report offers comprehensive profiles on these market players and assesses their current standing in the Asia Pacific pregnancy and ovulation testing market. Company history coupled with annual turnover, segmental share, SWOT analysis, growth strategies, new product launches, mergers and acquisitions (M&A) activities, and latest R&D initiatives are outlined in the report.

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