Wednesday, 17 March 2021

Cell Lysis and Disruption Market Growth Insight Analysis 2020-2025

 Market Forecast

Global Cell Lysis & Disruption Market is expected to cross USD 5.7 Billion by 2025 at a CAGR of 8.6%.

Market Synopsis

Cell lysis & disruption is a method in which the cell membrane is broken down in order to extract the nucleic acids or proteins from a cell. The choice of cell lysis method depends on the type of cells, concentration, application (post-processing) and efficiency required. The demand for cell lysis & disruption is increasing due to the rising number of research & development activities in the biotechnology industry. This is majorly attributed to the increasing adoption of biotech processes in the pharmaceutical, agricultural sector.

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Market Influencers

The rising focus on personalized medicine would directly drive the growth of the global cell lysis & disruption market. Strategic initiatives, mergers & acquisitions, partnerships, agreements, product launches, government approvals, and expansion of manufacturing facilities by major competitors are expected to positively affect market growth during the forecast period.   

Regional Analysis

On a regional basis, the Americas is anticipated to dominate the global cell lysis & disruption market owing to the growing clinical R&D budgets by both governments as well as public and private organizations in the pharmaceutical and biotech sector and increasing demand for novel therapeutics in the region.  Additionally, the rising prevalence of geriatric population along with various chronic diseases is contributing to the growth of this market. According to a report by the Population Reference Bureau, the number of older population (aged 65 and above) will rise to nearly 24% from 15% by 2060. Europe is expected to hold the second-largest position in the global cell lysis & disruption market owing to the presence of a strong academic & research base and availability of funding for research in the European countries. Moreover, rising healthcare expenditure is boosting the market in this region. Asia-Pacific is anticipated to be the fastest-growing region is due to the growing interest of major key players in emerging markets and rapidly developing healthcare infrastructure in this region. The Middle East & Africa has the least share of the global cell lysis & disruption market. Moreover, the major market share of the region is expected to be held by the Middle East region owing to the increasing government initiatives for the healthcare sector.  

Segmentation

The global cell lysis & disruption market has been segmented into technique, product, cell type, and end user.

By technique, the market has been segregated into reagent based and physical disruption. The reagent based segment has been further sub-segmented into detergent and enzymatic. The physical disruption further divided into mechanical homogenization, ultrasonic homogenization, pressure homogenization, and temperature treatments

By product, the market has been bifurcated into consumables and instruments. The consumables segment is estimated to hold major market share in the market due to the rise in funding of cell based research. Consumables has been further divided into reagent and kits, beads and disposables. The instrument segment has been further categorized as sonicators, homogenizers, French press, microfluidizer, and others.  

On the basis of cell type, the global cell lysis & disruption market has been classified as mammalian cells, microbial cells, and others.

The global cell lysis & disruption market, by end user, has been divided into research laboratories and institutes, pharmaceutical and biotechnology companies, and others.

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G-Protein Coupled Receptors Market Is Seeing Explosive Growth by Future Industry Winners: Forecast, 2020-2025

 G-Protein Coupled Receptors Market is expected to cross USD 4,200 Million by 2025 at a CAGR of 7.1% during the forecast period.

The growing use of G-protein coupled receptors in medicate disclosure and advancement forms is set to drive the demand of G protein-coupled receptors.

G-protein coupled receptors are most commonly prescribed for the treatment of cardiovascular disease, oncology, immunology, respiratory system, central nervous system (CNS), and others. GPCRs (G-protein coupled receptors) play a physiological role in the regulation of cardiac function in both health and disease and thus represent one of the largest class of surface receptors targeted by drugs.

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Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is expected to be the largest market owing to the presence of a large number of approved drugs that target G-protein coupled receptors. The G protein coupled receptors market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The European G protein coupled receptors market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The G protein coupled receptors market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The rising number of approved drugs that target GPCRs has boosted the growth of the G protein coupled receptors market, the market in Asia-Pacific is expected to be the fastest-growing. The G protein coupled receptor market in the Middle East & Africa has been divided into the Middle East and Africa.

Segmentation

The global G protein coupled receptors market has been segmented based on the product, assay type, and application.

The market, based on product, has been divided into cell lines, detection kits, cell culture reagents, ligands, and others. The detection kits segment is likely to be the fastest during the review period as they are ready to use kits that includes all cells and reagents to perform functional GPCRs assay in live cells thus driving the growth of the global G protein coupled receptor market.

The global G protein coupled receptor market has been bifurcated, on the basis of assay type, into functional calcium assays, cAMP functional assays, cGMP assays, GTP gamma S binding assays, ß-Arrestin Functional Assays, internalization assays, and others. Calcium functional assays are the fastest segment as it has numerous advantages such as user configurability, ease in the estimation of calcium flux thus driving the growth of this segment in the GPCR market.

The global G protein coupled receptors market has been segmented, based on application into the cardiovascular system, oncology, immunology, respiratory system, central nervous system, and others. The cardiovascular system is the largest segment as angiotensin II, and β-adrenergic receptors provide therapy for a wide range of cardiovascular disease such as heart failure. Approximately 17.9 million people die each year from cardiovascular disease thus rising the growth of G protein coupled receptor market.

Key Players

Some of the key players in the global G protein coupled receptor market are Thermo Fisher Scientific, Inc., Cisbio, Promega Corporation, Abcam PLC, PerkinElmer Inc., Merck Group, HD Biosciences Co., Ltd, QIAGEN, Enzo Life Sciences, and Inc.BD.

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Tuesday, 16 March 2021

Articaine Hydrochloride Market Detailed Industry Report Analysis 2020-2025

 The Global Articaine Hydrochloride Market is expected to register 8.5% CAGR and is anticipated to reach USD 1,889.0 million by 2025. 

Articaine is a form of a local amide anesthetic that is most commonly used in dentistry. The articaine is marketed as a colorless liquid in vials/cartridges (2ml in each vial/cartridge). It is available in two variants, i.e., Articaine-100 & Articaine-200. Articaine-200 is more potent than Articaine-100. The dosage can be based on the type and extent of surgical procedure, depth of anesthesia, degree of muscular relaxation, and condition of the patient. For pediatric patients, dosage based on their age, weight, the physical condition of the patient, and the extent of the surgical procedure.

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The articaine hydrochloride industry is growing rapidly. Articaine, with its greater ability to diffuse through tissues, become a very widely used local anesthetic in the European and Canadian markets.

Market Dynamics

Articaine hydrochloride is the most popular local anesthetic for dentistry. For example, in Germany, around 97% of the anesthetic used by dentists is articaine hydrochloride. The growth of the market is likely to be driven by increasing incidences of dental caries and other periodontal diseases, advancement in dental anesthesia delivery system device, increasing the use of articaine for dental surgery, innovative nature of the dental anesthetics industry, and vigorous research and development efforts. Periodontal disease is one of the major dental diseases that influence human populations worldwide at high prevalence rates. Periodontal diseases are more prevalent in Asia-Pacific. Lack of the most basic oral health education and limited availability of simple interventions like pain relief and emergency care for acute infection and trauma to the vast majority of the population, especially in the rural areas are major reasons for the high incidences of periodontal diseases in the region. According to the FDI World Dental Federation, more than 80% of people in Asia-Pacific, including countries such as India, Bangladesh, Nepal, Malaysia, and Indonesia, suffer from dental decay. Furthermore, 40–59% of the population in China and Australia suffer from dental caries.

Some of the popular local anesthesia other than articaine are prilocaine, lidocaine, mepivacaine, and bupivacaine. The availability and usage of alternative products are likely to thwart the growth of the articaine hydrochloride market during the forecast period.

Segmentation

The global articaine hydrochloride market has been segmented into application and end user.  Based on application, the global market has been segmented into infiltration, nerve block, and others. Based on end-user, the global market has been segmented into dental clinics, hospitals, and academics & research institutes. The dental clinics segment accounted for a market value of USD 798.5 million in 2018.

Key Players

The prominent players in the global articaine hydrochloride market are 3M (US), Anhui BBCA Pharmaceutical Co., Ltd. (China), Dentsply Sirona (US), Inibsa Dental S.L.U (Spain), Jinan Chenghui Shuangda Chemical Co., Ltd. (China), Jinan Ruixing Pharmaceutical Technology Co., Ltd (China), Manus Aktteva Biopharma LLP (India), Pfizer Inc. (US), Pierrel S.p.A (Italy), Sanofi (France), Septodont (France), Siegfried AG (Switzerland), and Sigma Aldrich (US).

Some of the key strategies followed by the players operating in the global articaine hydrochloride market were innovation, product development, acquisition, and expansion.

Regional Analysis

The global articaine hydrochloride market, based on region, is segmented into Europe, North America, Asia-Pacific, and the Middle East and Africa. The articaine hydrochloride market in Europe is the largest region in the market and is expected to develop continuously due to the increasing demand and focus on dental treatments. The growing awareness of preventative and corrective treatment in European countries is also one of the factors driving the growth of this market. The articaine hydrochloride market in Europe is mainly focusing on a new style of management system that would engage dental specialists to run more effective practices and permit them to concentrate on better clinical care.

North America accounted for the second-largest share in the global articaine hydrochloride market. The increasing acceptance of the articaine by dental professionals is one of the factors for the growth of the articaine hydrochloride market in this region.

Asia-Pacific is one of the fastest-growing markets for articaine hydrochloride. Although Australia is dominating the Asia-Pacific market with high adoption of new technology and its usage of dental applications, China, Japan, and India are the countries mainly responsible for the exponential growth of the articaine hydrochloride market in Asia-Pacific. The demand for articaine hydrochloride in India offers several growth opportunities owing to the rising awareness of new applications. In Asia-Pacific, India accounted for a market share of 8.5% in 2018.

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Stroke Post Processing Software Market– Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2024

 Stroke Post Processing Software Market is projected to list a CAGR of 6.48% to influence income generation of USD 1,294.24 Million by 2024. A stroke can be defined as the absence of blood flow to brain tissues, resulting in vascular assembly within the brain. Furthermore, increasing awareness regarding the benefit of stroke post-processing software in individuals and healthcare professionals would create more demand for these products, boosting the global stroke post-processing software market's growth.

Growth in the aging population in the stroke post processing software market will support the growth. As per stroke post processing software market analysts, the stroke post processing software market based companies will face certain challenges during the 2018 to 2024. The stroke post processing software market research report provides in-depth analysis of the installation, modality, type, and end-user segments. The stroke post processing software market research report presents factors such as underdeveloped infrastructure that could slow down the stroke post processing software market's growth.

Market Segmentation

The stroke post processing software has been segmented into installation, modality, type, and end-user . Based on the segment which is installation, the market is categorized on the basis of desktops, mobile phones and tablets. The global market for stroke post processing software is further segmented based on modality into CT Scan and MRI. Furthermore, the market, on the basis of type is segmented into hemorrhagic stroke, ischemic stroke, and others. The market based on end-users is segmented into hospitals & clinics, specialty centers, and others.

The stroke post processing software market report offers comprehensive study of the global market segments including installation, modality, type, and end-user. The analysts have also studied the stroke post processing software market's spread across the regional markets across many of the stroke post processing software market’s segments at country levels. The installation, modality, type, and end-user segments spread across the stroke post processing software market along with the subsegments are studied. The global market for stroke post processing software is spread across various product and service based segments. The stroke post processing software market research report highlights these key segments and offers forecasts based on primary and secondary data. The global stroke post processing software market research report presents key company profiles of organizations active across the stroke post processing software market.

Regional Overview

The presence of rigorous regulations may hinder the stroke post processing software market growth. The stroke post processing software industry research report suggests that companies in the stroke post processing software market could be supported by the surge in geriatric population levels as well as the increased occurrence of cases related to ischemic strokes during the forecast period. The stroke post processing software industry is set to register growth at a high CAGR owing to these key factors. The stroke post processing software market is spread across North America, Europe, Asia-Pacific, and other parts of the world. As per stroke post processing software market analysts, the stroke post processing software market is set to witness tremendous growth across installation, modality, type, and end-user segments. The global stroke post processing software market’s North American region covers stroke post processing software markets across the United States, Mexico, Canada, and others. Businesses present in the stroke post processing software market are also profiled and their strategies have been presented in detail in the stroke post processing software market research report.

The global stroke post processing software market across the European region covers Italy, France, Germany, and the United Kingdom. Furthermore, the stroke post processing software market research report provides details about the APAC region covering stroke post processing software markets from China, India, Australia, Japan, and others. The stroke post processing software market is also active across several other parts of the world. The stroke post processing software market report covers all these key regions including the Middle East, Africa, Brazil, and others active in the global stroke post processing software market..

Competitive Landscape

Stroke post processing software has seen tremendous growth, due to the joining of market players' efficiencies and the stroke post-processing software. However, lack of awareness and high cost would challenge the companies active in the stroke post processing software market. Furthermore, companies using growth strategies to stay ahead in the global stroke post processing software market are expected to help the market during the forecast period 2018 to 2024. As the stroke post processing software market report suggests that the stroke post processing software market will register a CAGR of 6.48% and reach a US$1,294.24 million by 2024, the market report highlights key areas stroke post processing software market based companies need to focus on. The stroke post processing software market research report projects a long term growth till 2024. Based on stroke post processing software market’s analysis on the basis of SWOT and Porters’ Five Force Model, the stroke post processing software market will rise during the forecast period 2018 to 2024, however the companies need to move ahead with caution. The stroke post processing software market research report highlights such key areas. 

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Global Forensic Swab Market size and forecast, 2020-2023

 The Global Forensic Swab Market is expected to register 5.8% CAGR and is anticipated to reach USD 49.09 Million by 2023. Forensic swabs are extensively used by forensic scientists and crime scene investigators for collecting a wide range of evidence-samples such as blood, saliva, and DNA. These samples are analyzed in the laboratory for desired results. Gathering biological samples for successive DNA analysis is one of the major applications for forensic swabs. Rising criminal activities, increasing adoption of DNA forensics, growing forensic biotechnology sector, and favorable government support are some of the major factors driving the market growth during the forecast period. However, factors such as the high price of DNA free forensic swabs and irregular supply of new products in the market are projected to restrain the market growth. However, the growing rate of chronic and infectious diseases, increased research and development investment (R&D), and technological advancements are expected to boost the market growth.

Additionally, the escalated level of spending from the government is anticipated to bolster the evolution of the market. Also, the expansion of the market into the untapped regional markets is forecasted to boost the level of development that can be achieved from the market. The market is projected to be restrained by the high costs DNA free forensic swabs and the relatively irregular supply of new products in the market.

Segmental Analysis

The segmental analysis of the forensic swab market is segmented on the basis of type of swab shaft, type, end-user, and region. On the basis of type, the forensic swab market is segmented into foam, flocked, and cotton tips. The foam type segment was found to be heading the market segment in 2017. The cotton swabs segment is projected to witness the highest CAGR through the forecast period. The segmentation on the basis of types of swab shaft segments the forensic swab market into wood stick shaft, polystyrene shaft, and others. The polystyrene shaft was found to be the topmost market portion in 2017 and is expected to observe the highest CAGR in the duration of the forecast period. The end user based segmentation of the market comprises of hospitals, forensic science laboratories, among others. The forensic science laboratories segment was in charge of the market in 2017 and is projected to carry on with its control in the forecast period.

Detailed Regional Analysis 

The regions of Europe, the Americas, Asia Pacific, and the Middle East and Africa are included in the regional analysis of the forensic swab market. The Americas region is responsible for the major market share in 2017 and is projected to control the forensic swab market. The Americas region is accredited for the principal regional market share due to factors such as the mounting number of forensic labs in the region, increasing number of criminal cases, and increased dependence on blood sampling. The rise in the number of forensic labs in the regions has also contributed to a growth in the number of microbiological tests. The development of laboratories in hospitals is also anticipated to support the forensic swab market in this region.

The European region is accountable for the ensuing principal market share in 2017. The expansion of the region is attributed to the increasing number of research labs and hospitals, and the escalation in accident cases is expected to boost the demand for swabs through the forecast period. The Asia Pacific region is estimated to exhibit a CAGR of 6.1% through the forecast period owing to the rising frequency of various diseases, demand for blood sampling, and an increasing number of forensic labs being set up in the region. On the other hand, the Middle Eastern and African region are estimated to see decelerated growth due to the restricted exposure to forensic labs and the low awareness levels in this region.

Competitive Analysis

The global forensic swab market’s growth is expected to be highlighted by the intense competition, frequent changes in government as well as rapid advances in the product mix.  The points related to cost, reliability, and quality of the products are expected to improve the chances for the growth of the manufacturers. The efforts undertaken to enhance the market dynamics such as improvement of infrastructure is expected to benefit the progress of the market in the long term. Thermo Fisher Scientific Inc., Sirchie, Merck KGaA, Copan Italia S.p.A., SARSTEDT AG & Co. KG, MWE, Luna, Puritan Medical Products, Becton, Dickinson and Company, and Medtech Forensics are some of the market players included in the report.

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Nerve Stimulators Market Analysis and Value Forecast Snapshot by End-use Industry 2020-2023

 Nerve stimulation is considered as a gold standard technique for the treatment of treat different types of health problems such as joint, or bone problems that occur in case of osteoarthritis or fibromyalgia, or low back pain, neck pain, neurological disorders, overactive bladder, and others. According to a study published in Research and Reports’ Urology journal in 2014, it is found that nerve stimulation is an effective intervention for OAB patients, who are not responsive to pharmacologic therapy. Even in case of neurological disorders, complex seizures are not being controlled by medication. Vagal nerve stimulation is most commonly recommended when medications aren't effective. Among neurological disorders, nerve stimulation therapy is most commonly used for epilepsy and depression. The most commonly used nerve stimulators are deep brain stimulator (DBS), vagus nerve stimulator (VNS), and spinal cord stimulator (SCS).

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Rising incidence of chronic health problems, technological improvements, increasing popularity of minimally invasive procedures, increasing geriatric population, and improvement in reimbursement policies are the key factors driving the nerve stimulators market.
However, the high cost of treatment and lack of skilled or trained physicians may hinder the growth of the market to an extent.
It is estimated that nerve stimulators market is expected to grow at a CAGR of 9.7% during the forecast period 2017-2023.
Taste the market data and market information presented through more than 296 market data tables and figures spread over 251 pages of the project report. Avail the in-depth table of content TOC & market synopsis on “nerve stimulators market research report–Global forecast till 2023.” 

Major Key Players in Nerve Stimulator Market

Some of key the players in the market are Boston Scientific Corporation, Cochlear Ltd, Medtronic plc, St Jude Medical, Inc., Cyberonics, Inc., Aleva Neurotherapeutics SA, NeuroPace, Inc, and others.

Regional Analysis

The Americas dominate the nerve stimulators market owing to the rising prevalence of chronic diseases, a well-developed technology, high healthcare expenditure, and the presence of the leading players. According to a study published in Drug and Alcohol Dependence journal in 2017, more than 100 million adult Americans are living with chronic pain. Chronic low back pain and headaches are the most commonly diagnosed conditions. It is also stated that conditions are more prevalent in women than men i.e. 34.3% in women, and 26.7% in men in the U.S.

Europe holds the second position in the nerve stimulators market. It is expected that the support provided by the government bodies for research & development, along with a well-developed technology drives the market in the European region.

Asia Pacific region is projected to be the fastest growing region during the forecast period. Increasing need for cost-effective nerve stimulators, rapidly improving technology, and the presence of huge patient pool drive the growth of this market in Asia Pacific region.

The Middle East and Africa hold the least share in the market owing to the presence of poor and slow developing countries, especially, in the African region. 

Segmentation

The global nerve stimulators market is segmented on the basis of type, application, and end-users.

On the basis of the type, the market is segmented into deep brain stimulator (DBS), vagus nerve stimulator (VNS), and spinal cord stimulator (SCS).

On the basis of the application, the market is classified as chronic pain, depression, dystonia, epilepsy, Parkinson's disease, and others.

On the basis of the end -users, the market is segmented into ambulatory surgical centers, hospital & clinics, and trauma centers.

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Tissue Microarray Market – Revolutionary Trends 2023

 The Global Tissue Microarray Market is expected to register a CAGR of 10.54% and is anticipated to reach USD 10,914.54 million by 2023. Tissue microarrays are paraffin blocks that are created by separating cylindrical tissue cores from different paraffin donor blocks and re-embedding these into a microarray at defined array coordinates. With the help of tissue microarray, up to at least 1000 tissue samples can be arrayed into a single paraffin piece. It allows simultaneous analysis of molecules present in DNA, mRNA, and protein levels under identical, standardized conditions on a single glass slide. This adaptable strategy, in which data analysis is automated, facilitates retrospective and prospective human tissue studies.

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The increasing application in drug discovery, increasing prevalence of cancer, growing advancements in biotechnology and pharmaceutical companies, and rising demand for cost-effective and accurate diagnostic methods are the major drivers propelling market growth. However, tissue microarray may not be fruitful for heterogeneous cancers, which is likely to constrain the growth of the market.

Market Dynamics

The prevalence of cancer is one of the crucial factors that drive the growth of the tissue microarray market. According to the American Cancer Society, in 2017, nearly 13% of all cancers diagnosed in adults aged 20. It further stated that rates of liver cancer, thyroid cancer, and melanoma are increasing from last few years. According to US Breast Cancer Statistics, about 1 in 8 US women (about 12%) will develop invasive breast cancer throughout their lifetime. In 2017, an estimated 252,710 new cases of invasive breast cancer were expected to be diagnosed in women in the US, along with 63,410 new cases of non-invasive (in-situ) breast cancer.

Moreover, increasing advancements in biotechnology and pharmaceutical companies and growing demand for cost-effective and accurate diagnostic methods have fueled the growth of the market. On the other hand, tissue microarray is that it may not be fruitful for heterogeneous cancers anticipated to hamper the market growth.

Segmentation

The global tissue microarray market has been divided into the procedure, technology, application, and end user. By procedure, the market has been segregated into immunohistochemistry, fluorescent in-situ hybridization, and frozen tissue array. Based on technology, the market has been segmented into DNA microarray, polymerase chain reaction (PCR), next-generation sequencing, northern blotting, and western blotting. Based on the application, the market has been bifurcated into oncology, gene expression profiling, SNP detection, double-stranded B-DNA microarrays, comparative genomic hybridization, and sequencing bioinformatics. By end-user, the market has been classified as pharmaceutical and biotechnological companies and research organization. The research organization segment accounted for a market value of USD 1876.02 million in 2016.

Key Players

The prominent players in the global tissue microarray market are Agilent Technologies, Illumina, Inc., Protein Biotechnologies Inc., Asterand Bioscience, Pantomics Inc., Applied Microarrays, Arrayit, Phalanx Biotech, QIAGEN, Takara Bio, Perkin Elmer, and Merck Sharp & Dohme Corp.

Some of the key strategies followed by the players operating in the global immunoassay in the R&D market were innovation, product development, acquisition, and expansion.

Regional Analysis

The global tissue microarray market, based on region, is divided into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is estimated to dominate the global tissue microarray market during the forecast period. This is attributed to the increase in the prevalence of cancer in the Americas, leading to the requirement for tissue microarrays. Besides, increasing application in drug discovery is also responsible for the growth of the market. Europe holds the second position in the market. Increasing emphasis on rapid diagnosis and treatment of cancer and infectious diseases, change in lifestyle, and high prevalence of cancer among geriatric population drives this market in Europe.

Additionally, the companies operating in the market are mainly focusing on mergers and acquisition, which is expected to support market growth. Asia-Pacific is expected to be the fastest-growing market for tissue microarray. Increasing prevalence of cancer, awareness among the people about their health, and changing lifestyle contribute to the growth of this market. In the Asia-Pacific region, China accounted for a market share of 21% in 2016. Furthermore, the market in the Middle East & Africa is expected to witness steady growth due to the lack of advanced medical facilities and less improvement in the healthcare domain.

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