Electronic Trial Master File (eTMF) Systems Market Revenue Analysis by 2027

 Global eTMF Systems Market is expected to reach a value of USD 1825 Million by 2025, at a CAGR of 13.11% during the assessment period of 2019 to 2025.

The pharmaceutical, as well as the biotechnology companies, face a major challenge to maintain a central repository for the storage of clinical trial documents for use in regulatory submissions. Therefore, there emerges a need to store all the data produced by these companies effectively. As a result, software companies have developed electronic trial master file systems that aid these companies as well as the contract research organizations in systemized storage of files. Moreover, in comparison to the traditional storage systems, electronic trial master file systems facilitate content classification and easier interoperability in clinical trial operations. Therefore, the major companies are continuously involved in new product launches to gain a competitive edge over the other players.

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The growth of the global eTMF systems market is fueled by several factors such as rising activities in terms of acquisitions, new solution and service deployments, and collaborations by key players operating in the market, coupled with the increasing number of clinical trial studies. For instance, in October 2019, SureClinical Inc. launched a transparent eTMF pricing policy. To provide value to the prospective users, the company has posted its prices and terms online to battle price discrimination in this industry. However, budget constraints of the small and medium-sized enterprises, along with the dearth of skilled professionals for operating the electronic systems, can hinder the preference of such solutions. As a result, such elements can hamper the growth of the market during the forecast period.

Several market players currently dominate the global eTMF systems market. The key players are involved in product launches and strategic collaborations to strengthen their market positions. For instance, in June 2018, Phlexglobal, a UK-based specialist provider of TMF and eTMF management solutions, is adopting Version 1 of the eTMF Exchange Mechanism Standard (eTMF-EMS) of the TMF Reference Model (TMF-RM) into PhlexEview, the company’s eTMF technology. Such strategies push the growth of the eTMF systems market.

Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas held the maximum share in the base year 2018, owing to the presence of established key players in countries such as the US and Canada. The eTMF systems market in the Americas has been segmented into North America and Latin America, with the North American market divided into the US and Canada. The European eTMF systems market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The eTMF systems market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The eTMF systems market in this region is anticipated to be the fastest-growing during the assessment period due to the increased adoption rate of eTMF software and services in the Asian countries. The eTMF systems market in the Middle East & Africa has been divided into the Middle East and Africa.

Segmentation

The Global eTMF Systems Market has been segmented based on Component, Deployment Mode, and End User.

The global eTMF systems market has been segmented, based on the component, into software and services. The software segment is expected to hold the majority share of the market owing to the increasing number of solution launches by the prominent players in recent years. The services segment is expected to be the fastest-growing due to the increasing uptake of eTMF services by pharmaceutical and life science companies.

The global eTMF systems market, based on deployment model, has been segmented into cloud/web-based, and on-premise. The cloud/web-based segment holds the maximum share owing to the technological advancements in cloud-based solutions in recent years.

The end-users of the market are pharmaceutical and biotechnology companies, contract research organizations, and others. The increasing number of clinical trials conducted by pharma firms is leading to the market size of the pharmaceutical and biotechnology companies’ segment.

Key Players

Some of the Key Players in the Global eTMF Systems Market are Aurea, Inc. (US), Covance Inc. (US), ePharmaSolutions (US), MasterControl, Inc. (US), Oracle (US), Phlexglobal (UK), SureClinical Inc. (US), TransPerfect (US), Veeva Systems (US), and Wingspan (IQVIA) (US).

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Lupus Market size in terms of volume and value 2020-2027

 The Global Lupus Market is expected to grow significantly over the forecast period. It is anticipated that the market held a market value of USD 1.48 billion in 2017 and is projected to grow at a CAGR of 11.2% over the forecast period. Lupus is a systemic autoimmune disease that causes inflammation throughout the body.  In patients with lupus, the immune system attacks healthy cells and tissues of the body which can result in damage to many parts of the body including the skin, joints, kidney, heart, lungs, blood vessels, and brain. The factors such as the rising prevalence of lupus, ongoing medical advancements in the treatment of systemic lupus erythematosus, increasing research and development activities are expected to drive market growth during the forecast period. According to the Lupus Foundation of America, about 1.5 million Americans have a form of lupus, and about 16,000 new cases are reported each year in the Americas. Despite the drivers, the factors such as strict government regulation and increasing prices of lupus drugs may hamper the market growth over the assessment period.

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Currently, a large number of companies are present in the lupus market. The prominent market players are involved in the development of new products and product launches. For instance, in July 2017, GlaxoSmithKline received FDA approval for a new self-injectable formulation of Benlysta for the treatment of adult patients with systemic lupus erythematosus.  

Segmentation

The Global Lupus Market has been segmented into types, treatment, and end user. The global market, on the basis of type, has been segmented into systemic lupus erythematosus, cutaneous lupus erythematosus, drug-induced lupus erythematosus, and neonatal lupus. The systemic lupus erythematosus segment is expected to hold the largest market share owing to the growing prevalence and increasing drug development in recent years.

On the basis of treatment, the market has been segmented into nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs, corticosteroids, immunosuppressants, biologics, and other.

On the basis of end user, the market has been segmented into hospital & clinics, diagnostic laboratories, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The lupus market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European lupus market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The lupus market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The lupus market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key Players

Aurinia Pharmaceuticals, Inc., Bristol-Myers Squibb Company, Cadila Healthcare, GlaxoSmithKline plc, Mylan N.V., F. Hoffmann-La Roche AG, Pfizer, Inc., Sanofi, Lycera Corporation, Merck KGaA, and Eli Lily and Company are some of the key players in the global lupus market.

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Desalting and Buffer Exchange Market Volume Analysis, Size, Share and Key Trends 2020-2027

 Market Scenario

The Global Desalting and Buffer Exchange Market is expected to grow significantly over the forecast period. It is anticipated that the market held a market value of USD 615.20 million in 2017 and is projected to grow at a CAGR of 10.5% over the forecast period. Desalting is a separation process removes soluble low molecular weight substances from protein and nucleic acid samples. Buffer exchange is the replacement of one set of buffer salts with another set.

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Additionally, during the preparation of biological samples, buffer exchange is an essential step, as it prepares the sample for downstream applications. The factors such as growing demand for monoclonal antibodies, increasing research and development expenditure by the biopharmaceutical companies, and growing focus on proteomic and genomic research is expected to drive the market growth over the forecast period.  According to the Office for National Statistics, gross domestic expenditure on R&D was Euro 33.1 billion (USD 35.2 billion) in 2016. Despite the drivers, the lack of skilled professionals is expected to restrain the market growth.

Segmentation

The Global Desalting and Buffer Exchange Market has been segmented into technique, product, and application. On the basis of technique, the market has been segmented into filtration, chromatography, and precipitation. The filtration segment has been further segmented into ultrafiltration and dialysis. The chromatography segment has been segmented into size-exclusion chromatography and others.

The market, by product, has been segmented into kits, cassettes, filter plates, spin columns, membrane filters, and others.

The market, by application, has been segmented into bioprocess applications and diagnostic applications. The bioprocess segment is expected to account for the largest market share in 2017. The market growth of the segment is attributed to the increasing demand for biopharmaceutical products.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The desalting and buffer exchange market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European desalting and buffer exchange market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. 

The desalting and buffer exchange market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The desalting and buffer exchange market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key Players

Merck KGaA, GE Healthcare, Sartorius AG, Thermo Fisher Scientific, Danaher Corporation, Agilent Technologies, Inc., Bio-Rad Laboratories, Avantor, Repligen Corporation, Bio-works Technologies Ab, Phynexus, Inc., and Norgen Biotek Corp. are some of the key players in the global desalting and buffer exchange market.

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Global Retinal Implants Market to Witness Steady Growth through 2027

 Market Forecast

Global Retinal Implants Market likely to exhibit a healthy growth over the next couple of years. Retinal implants have emerged as an innovative technology in the field of ophthalmology. They are being used for improving eyesight of people with partial or complete blindness. The technology is still in its nascent stage hence a mixed speculation continues to hover around it. Investment in retinal implants and prostheses R&D has increased in recent years owing to their immense market potential. Several private eyecare companies have entered the frame and are focusing on introducing more effective retinal implants. Majority of retinal implants that are currently available in the market are aimed at partially restoring useful eye vision. Such implants are effective in treating vision loss caused due to age-related macular degeneration (AMD) and retinitis pigmentosa (RP). Visual devices such as bionic eye and visual prosthesis are expected to have bigger impact in years to come, which in turn will pave the way for retinal implant market.

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Report Synopsis

This MRFR report offers a thorough analysis of the global retinal implants market. The primary objective of the report is to analyze the current market landscape and its future potential. All the relevant parameters have been considered for market analysis. The report also includes a discussion on the growth opportunities, drivers and restraints. 

Competition Tracking

Philips Healthcare, Retina Implant AG, Second Sight Medical Products, Inc. Bionic Eye Technologies, Inc., Bionic Vision Australia, VisionCare Ophthalmic Technologies, Inc, Abbott Vascular.

The report offers insights into the leading market players and presents an assessment of their current market position. Company information with regards to revenue, segmental share, geographical income, SWOT, growth strategies, new product launch, M&A activities, and the latest R&D initiatives is also available in the report.

Segmentation

The global retinal implants market has been segmented into device type, disease indication, and end user. By device type, the market has been segmented into retina implant alpha AMS, Argus II, implantable miniature telescope, and others.  By disease indication, the market has been segmented into age-related macular degeneration (AMD) and retinitis pigmentosa. By end user, the market has been segmented into multi-specialty hospitals, ophthalmic clinics, and research institutes.

Regional Analysis

North America, Europe, Asia Pacific, and the Rest of the World are the key markets for retinal implants. North America accounts for a substantial share of the global market. Higher availability of the product, improving reimbursement scenario and higher affordability in the region supports the growth of the North America market for retinal implants. Presence of highly skilled surgeons to perform immensely complex surgical procedure also accelerates adoption in the region.

In Europe, the market is driven by an increase in R&D activities and the expansion of clinical trials.

Presence of developing countries such as India, China, and Japan, who outlay massive amounts on healthcare expenditure, coupled with growing disposable income and affordability supports the growth of the market in Asia Pacific.

Rest of the World market is expected to fare well in the coming years since various market players are foraying into the untapped regions to leverage the potential they offer for market expansion.

Research Methodology

Market Research Future (MRFR) employs a multi-layered analysis module for presenting accurate industry outlook. The combination of primary and secondary research processes for analysis of governing factors and macro-economic indicators of the market. Detailed surveys and interviews are conducted with key opinion makers across the value chain for collection of primary data. Secondary research processes are leveraged for verification of collected data through valuable inputs from SEC filings, white paper references, paid databases, research publications and other credible sources available in public domain. Additionally, top-down and bottom-up approaches are utilized to extrapolate data, which is then verified using a powerful data triangulation technique. These comprehensive research methods ensure accuracy and objectivity of the market foresight.

For the scope of the research, MRFR’s report offers a comprehensive segmental analysis of the global market for petroleum coke (fuel-grade)

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Retinal Detachment Market 2020 by Rising-Trends, Growth Analysis, Industry Share, Product Types, User-Demand, Business Strategy and Comprehensive Valuation till 2027

 Market Scenario:

Retinal Detachment Market is expected to exhibit significant growth over the forecast period. The market is projected to register a CAGR of 6.2% over the forecast period and is estimated to reach USD 2,892.5 Million by 2025.

Retinal detachment is a critical situation of the eye wherein a thin layer of tissue (the retina) at the back of the eye pulls away from its normal position. This condition separates the retinal cells from the layer of blood vessels that provides oxygen and nourishment to the eyes.

Factors such as the rising cases of retinal detachment and growing technological advancements are expected to drive the market growth. Furthermore, the rise in the number of eye surgeries is also expected to drive the market growth.

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However, the high price of retinal surgery instruments, limited availability of skilled professionals, and lack of awareness in the developing economies are expected to hamper the market growth.

Segmentation

The Global Retinal Detachment Market has been segmented into Condition Type, Treatment, End User, and Region.

Based on condition type, the global retinal detachment market has been divided into rhegmatogenous retinal detachment, tractional retinal detachment, and exudative retinal detachment.

The global retinal detachment market, by treatment, has been segmented into photocoagulation (laser surgery), cryopexy (freezing), pneumatic retinopexy, scleral buckling, and vitrectomy.

The global retinal detachment market, by end-user, has been segmented into hospitals & clinics, specialty centers, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The retinal detachment market in the Americas has further been segmented into North America and Latin America, with the North American market divided into the US and Canada.

The European retinal detachment market has been segmented into Western Europe and Eastern Europe. The market in Western Europe has further been classified into France, Germany, Spain, the UK, Italy, and the rest of Western Europe. 

The retinal detachment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific.

The Middle East & Africa retinal detachment market has been segmented into the Middle East and Africa.

Key Players

Carl Zeiss Meditec AG (Germany), Meridian AG (Switzerland), IRIDEX Corporation (US), Ellex Medical Lasers Ltd (Australia), FCI (US), Millennium Surgical Corp. (US), BVM Medical Limited (UK), Lombart Instrument, Inc. (US), and Welch Allyn (US) are some of the key players operating in the global retinal detachment market.

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Leprosy Treatment Market Excessive Growth Opportunities Estimated to be Experienced 2020-2027

 Market scenario:

Leprosy is a chronic infection caused by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis causing granulomas of the nerves, respiratory tract etc. The granulomas may result in lack of ability to feel pain, especially in the extremities such as finger tips. The global market for leprosy is falling due to early detection and awareness campaigns and integration of basic leprosy services into general health services of many countries.

Considering all these factors the market for leprosy treatment is expected to reach $ 3.5 billion by the end of 2023, this market is projected to growing at a CAGR of ~ 3.2 % during 2017-2023.

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Key players

• Glaxo Smithcline
• Systopic Laboratories Pvt. Ltd.
• Cadila Pharmaceuticals
• Acme Pharmaceuticals
• Macleods Pharmaceuticals
• Novartis International AG
• Astra Zeneca
• Lark Laboratories Ltd.

Segments:

The global leprosy treatment market is segmented on the basis of drug class, disease type and market channel. Based on drug class, the market has been segmented as sulfone, phenazine, derivative, anti-tubercular drugs and others. Based on the disease type, the market has been segmented as paucibacillary leprosy, multibacillary leprosy. Based on the end users, the market has been segmented as private, contract and others.

Regional analysis

US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. The faster market uptake of new technology in the US is also an important driver of the market for global leprosy treatment. Europe is the second largest market due to large disposable income and rising awareness. The Middle East & Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The poor regions of Africa are expected to be a laggard due to poor economic and political conditions and poor healthcare penetration.Asia Pacific region is expected to have the most potential and it is estimated to be led by China and India.

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Flexible Spinal Implants Market size in terms of volume and value 2020-2027

 Technological advancements in spine implants, increasing aging and obese population, rising cases of spine deformities, demand for minimally invasive spine surgery, growth in the number of hospitals offering spinal surgeries are fueling the growth of global flexible spinal implants market. The market restraints are stringent product approval process, uncertain reimbursement scenario, high cost of treatment procedures, concerns about safety of advanced products etc.

Considering all these factors the market for flexible spinal implants is expected to reach 4 billion USD by the end of 2023, this market is projected to growing at a CAGR of ~ 13.2 % during 2017-2023.

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Key Players of Global Flexible Spinal Implants Market:

Key players profiled in the report are Paradigm Spine LLC, Medtronic plc., Abbott Spine, Inc.,  Raymedica, K2M Group Holdings, Stryker Corporation, Zimmer Biomet Holdings, Inc., B. Braun Melsungen AG, Alphatec Holdings, Inc., NuVasive, Inc., Orthofix International N.V., and others.
Intended Audience

• Global flexible spinal implants solution providers, manufacturers & suppliers
• Research and development (R&D) companies
• Market research and consulting service providers
• Academic institutes and universities

Market Segments:

The global flexible spinal implants market is segmented on the basis of type and applications. Based on type, the market has been segmented as rods, hooks, pedicle screws, plates, cages and other. Based on the applications, the market has been segmented as thoracic, lumbar, cervical, artificial discs and other.

Study objectives:

• To provide a detailed analysis of the market structure along with estimated future growth forecast for the next 6 years about various segments and sub-segments of the global flexible spinal implants market.
• To provide insights about factors affecting the market growth.
• To analyze the global flexible spinal implants market based on various factors – price analysis, supply chain analysis, Porters Five Force analysis etc.
• To provide past and estimated future revenue of the market’s segments and sub-segments with respect to four main geographies and their countries – Americas, Europe, Asia Pacific along with Middle East & Africa.
• To provide country level analysis of the market with respect to the current market size and future growth prospects.
• To provide country level analysis of the market’s segments which includes by type and applications.
• To provide overview of key players and their strategic profiling in the market, comprehensively analyzing their core competencies, and drawing a competitive landscape of the market.
• To track and analyze developments which are competitive in nature such as joint ventures, strategic alliances, mergers and acquisitions, new disease developments along with research and developments that are currently taking place in the global flexible spinal implants markets.

Regional Aanalysis:

US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness. Asia Pacific region is the fastest region because of large unmet needs which is led by China and India. The Middle East and Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The poor regions of Africa are expected to be a laggard due to poor economic and political conditions.

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