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Sunday, 18 April 2021

Obstructive Lung Disease Market : Dynamics, Segments, Size and Demand, 2020–2027

Obstructive lung disease is a category of respiratory disease characterized by airway obstruction. Many obstructive diseases of the lung manifest due to the narrowing of bronchi which often cause excessive contraction of smooth muscles. The major types of obstructive lung disease include asthma, bronchiectasis, bronchitis and chronic obstructive pulmonary disease (COPD). Increase in prevalence of COPD and asthma patients, rising geriatric population, increase in pipeline products, growing government and non-government initiatives for spreading awareness are the major factors driving the growth of the global obstructive lung diseases market.

As per the Global Burden of Disease study, it is estimated that chronic obstructive pulmonary disease caused 3.2 million deaths globally in 2015. Disease burden due to COPD was the highest in India, Nepal, Papua New Guinea, and Lesotho. COPD manifests itself as an occupational hazard in people working in agriculture, mining, plastics, and other industries.

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Governments across each country have implemented regulations for the production, standardization, and utilization of COPD devices. These devices are divided into categories –Class-I, Class-II, Class-III, and Class-IV, depending upon the level of risk associated.

However, stringent government regulatory requirement for the approval of asthma and COPD drugs, side effects associated with the drug treatment, and patent expiry of drugs restrict the market growth.

The global market of obstructive lung disease is expected to grow at a CAGR of approximately 8.5% during the forecast period 2017-2023.

Intended Audience

Obstructive Lung Disease Drug Suppliers
Obstructive Lung Disease Drug Manufacturers
Obstructive Lung Disease Device Suppliers
Obstructive Lung Disease Device Manufacturers
Research And Development (R&D) Companies
Medical Research Laboratories
Academic Medical Institutes and Universities

Segmentation

The obstructive lung disease is segmented on the basis of disease type, product type, drug class, route of administration and end-users.

On the basis of disease type, the market is segmented into asthma, bronchiectasis, bronchitis and chronic obstructive pulmonary disease (COPD), and others

On the basis of product type market is segmented into inhalers, and nebulizers and others. Inhalers are divided into Drug Powder Inhalers (DPIs), Metered Dose Inhalers (MDIs), Soft Mist Inhalers (SMIs) and others. Moreover the nebulizers are divided into compressor nebulizers, ultrasonic nebulizers, and mesh nebulizers

On the basis of drug class, the market is segmented into combination drugs, leukotriene antagonists (LTA), inhaled corticosteroids (ICS), anticholinergics, short acting beta agonists (SABA), long acting beta agonists (LABA), and others. Furthermore, the Combination products is divided into seretide/advair, symbicort, relvar/breo ellipta, flutiform, dulera, and others. Leukotriene Antagonists (LTA) is divided into singulair and others. Inhaled Corticosteroids (ICS) is divided into qvar, pulmicort, aerospan, flovent, and others. Anticholinergics is divided into Spiriva and Others. Short Acting Beta Agonists (SABA) is divided into proair, ventolin, and others.

On the basis of route of administration, market is segmented into oral, inhaler, intravenous, subcutaneous, and others

On the basis of end-user, the market is segmented into hospitals & diagnostic centers, academic institutes, pharmaceutical & biotechnology companies and others.

Key Players

The leading market players in the Asthma and COPD Drug focus to expand their business operations in the emerging countries. The companies operating in the market have consistently introduced innovative solutions to enhance their product portfolio. Product approval and clinical trial are observed as the two prominent growth strategies adopted by the key market players.

Some of key the players in the global obstructive lung disease market are GlaxoSmithKline (GSK) (U.K), Novartis AG (Switzerland), Merck & Co. Inc. (U.S), Abbott Laboratories (U.S), Boehringer Ingelheim (Germany), AstraZeneca (U.K), Roche Holding AG (Switzerland), Teva Pharmaceutical Industries (Israel), Vectura Group (U.K), Pfizer Inc. (U.S), Mylan (U.S.), Aerovance Inc. (U.S.), Alkermes Inc. (U.S.), Almirall SA. (U.S.), Genentech Inc. (U.S.), Sepracor, Inc. (U.S.), Skyepharma plc (U.S.).

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Future of Moyamoya Disease Market Analyzed in a New Study 2027

Market Scenario

Moyamoya disease (MMD) is a chronic, cerebrovascular disease characterized by progressive stenosis in the internal carotid artery and an abnormal vascular network at the base of the brain. The stroke is one of the significant symptoms of moyamoya disease, which further leads to paralysis of the face, arms, and legs, loss of speech, and temporary loss of neurologic function of body parts, visual disturbances, headaches, developmental delay, and seizures.

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According to the National Organization for Rare Diseases, in Japan, moyamoya disease is estimated to occur in 1 per 1 million people, and the condition is more prevalent in females under the age of 20. It is also reported that nearly 10% of cases of moyamoya disease in Asian countries have a genetic cause. Recently, two major mutations have been found to be associated with a specific population of moyamoya patients i.e. R179, and RNF213 mutations.

Intended Audience

Pharmaceutical Companies
Research and Development (R&D) Companies
Diagnostic Laboratories
Government Research Institute
Academic Institutes and Universities

Key Players

Some of key the players in the global moyamoya disease market are Abbott Laboratories, Boston Scientific Corporation, Cephalon, Inc., Cordis Corporation, Eisai Co., Ltd, GE Healthcare, Genentech Inc., GlaxoSmithKline PLC., Johnson & Johnson, Koninklijke Philips N.V., Medtronic plc, Merck & Co. Inc., Novartis AG, Pfizer, Inc., Sanofi, Siemens, Stryker,, Sunovion Pharmaceuticals, Inc., UCB Pharma Ltd., Valeant Pharmaceuticals International, Inc. and others.

It is noted that growing public awareness and technological advancements are the key factors driving the moyamoya disease market. Nowadays, people are becoming more aware of different types of neurological disorders. Government and other different organizations have started educating people about hygiene and diseases through seminars, and conferences. People are becoming more aware and health conscious. Thus, increasing awareness has provided a push to the growth of the market. The new and existing marketers are also contributing to control this condition. For instance, on April 13, 2016, Silk Road Medical, Inc., received FDA approval for its next-generation ENROUTE Transcarotid Neuroprotection System (NPS). The NPS is specifically designed and indicated for transcarotid artery revascularization.

Various other factors such as increased incidence of neurological disorders, unmet medical needs, increasing government assistance, improving regulatory framework, increasing adoption rate, and rising funding and reimbursement are continuously contributing to the growth of the global moyamoya disease market.

Despite these drivers, there are some issues associated with moyamoya disease market. The challenges in research and development, cost of treatment, side-effects of treatment, the presence of misbranded and spurious drugs, and poor healthcare system in low and middle-income countries, may hinder the growth of the market to an extent.

It is estimated that the moyamoya disease market is expected to grow at a CAGR 7.0% during the forecast period of 2017-2023.

Segmentation

The global moyamoya disease market is segmented on the basis of diagnosis, treatment, and distribution channels.

On the basis of the diagnosis, the market is classified as a cerebral angiogram, magnetic resonance imaging (MRI), magnetic resonance angiogram (MRA), computed tomography (CT) scans, transcranial Doppler ultrasound, positron emission tomography (PET) scan, and electroencephalography (EEG).

On the basis of the treatment, the market is classified as surgical treatment and non-surgical treatment. The surgical treatment is further classified as pial synangiosis, indirect procedures, and direct arterial bypass. The sub-segment of indirect procedures includes EDAS (encephaloduroarteriosynangiosis), EMS (encephalomyosynangiosis), Omental transposition/transfer, and dural inversion. The non-surgical treatment is further classified as anticoagulation and antiplatelet therapy, and others. The sub-segment of anticoagulation and antiplatelet therapy include heparin, warfarin, aspirin, and others.

On the basis of the distribution channel, the market is segmented into hospitals, clinics, diagnostic centers, drug stores, pharmacies and others.

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Thumb Arthritis Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

Market Scenario:

The Global Thumb Arthritis Market is expected to grow at an approximate CAGR of 8.1% during the forecast period.

Thumb or carpometacarpal (CMC) joint arthritis is a common type of arthritis affecting the hands. In the patients with thumb arthritis, the cushion-like cartilage inside the CMC joint breaks down, causing the bones to rub against each other. Some of the common symptoms of the disease are inclusive of thumb joint pain, thumb base swelling, besides others. The prevalence of the thumb arthritis is increasing which is the major driver for the market growth. In 2016, according to a study published in the HAND (American Association for Hand Surgery) journal, the prevalence of the thumb CMC osteoarthritis was estimated to be around 8% to 12% in the general population. Moreover, growing geriatric and obese population along with the rising healthcare expenditure is estimated to boost the market growth during the forecast period. According to the World Health Organization in 2016, approximately more than 1.9 billion adults, were estimated to be overweight, accounting for 650 million obese people. Additionally, according to the World Health Organization, the world’s geriatric population is estimated to reach 2 billion by 2050 from 900 million in 2015. However, the high cost of the surgical therapeutics along with related complications is estimated to restrain the market growth during the forecast period. According to a study published in the Plastic and Reconstructive Surgery journal in 2016, the cost of therapeutic trapeziectomy with LRTI for a majority of the patients (89%) was estimated to be about around USD 2,576.

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Segmentation

The global thumb arthritis market is segmented on the basis of type, diagnosis, treatment, and end user.

On the basis of the type, the market is segmented into osteoarthritis thumb arthritis, rheumatoid thumb arthritis, and others.

On the basis of the diagnosis, the market is segmented into physical examinations, imaging, fine needle aspiration (FNA), and others. The imaging segment is sub-segmented into X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and others.

On the basis of the treatment, the market is segmented into thumb exercise, medication, surgery, and others. The medication segment is sub-segmented into OCT medications, prescription medications, and others. The OCT medications, by treatment, is further segmented into acetaminophen, ibuprofen, and others. The prescription medications sub-segment, by treatment, is further segmented into celecoxib, meloxicam, and others. The surgery segment is sub-segmented into trapeziectomy, osteotomy, and others.

On the basis of the end users, the market is segmented into hospitals & clinics, research organizations, retail pharmacies, and others.

Key players in global thumb arthritis market

The key players in the global thumb arthritis market are inclusive of BioPro (U.S.), McKie Splints (U.S.), AbbVie Inc. (U.S.), F. Hoffmann-La Roche Ltd (Switzerland), Amgen Inc. (U.S.), Pfizer Inc. (U.S.), Carestream Health. (U.S.), General Electric Company (U.K), and others.

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Trends in the Kidney Infection Market 2020-2027

Market Scenario

Kidney infection is a result of infection in the bladder that spreads to the kidney. Most common bacteria causing kidney infection is E. coli. Kidney infections are very common, especially, an aging population. The blood test is performed to make sure that the kidneys are functioning normally. The urine test, called a urinalysis, detects any abnormal cells or proteins that relate to a kidney problem. If the blood and urine tests are normal, then no other tests are required. In some cases, these infections are diagnosed when a person undergoes an ultrasound examination or CT scan of the abdomen for some other reason. Additionally, the urologist may suggest an X-ray examination called “Voiding Cystourethrogram”.

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Increasing prevalence of kidney infections, increasing investment by biotechnology and pharmaceutical industries in R&D, and rising need for the better treatment methods drive the growth of the market. Furthermore, favorable reimbursement policies, increased application and significant investments in the development of new technologies for the treatment of diseases are likely to fuel the market growth during the forecast period. Moreover, increasing geriatric population is projected to boost the market growth. Established market players in the developed countries lead the globalization by pushing new products and services into the developing countries and emerging economies. However, higher treatment cost may hinder the market growth over the review period.

As per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Kidney disease is often referred to as a “silent disease” as there are no symptoms in its early stages and can go undetected. Chronic kidney disease (CKD) is a global health burden risk factor for cardiovascular disease (CVD). High blood pressure and diabetes are the main causes of CKD. The high economic cost to health systems and decreased productivity are the major drawbacks of kidney diseases. NIDDK also stated that the overall prevalence of Chronic Kidney Disease (CKD) in the general population is approximately 14%. It also stated that in 2013, Medicare spending for patients with CKD aged 65 and older exceeded USD 50 billion, which accounted for 20% of total Medicare spending in this age group. Over 70% of the Medicare spending for CKD patients aged 65 and older was incurred by those who also had diabetes, congestive heart failure, or both.

The global kidney infections market is expected to grow at a CAGR of ~5.2% during the forecast period 2017-2023.

Segmentations

The global kidney infection market is segmented on the basis of diagnosis, treatment, and end user.

On the basis of the diagnosis, it is segmented into dipstick urine test and imaging test. The imaging test is further segmented into ultrasound, CT scan, voiding cystourethrogram, and others.

The treatment segment is divided into medication, dialysis, kidney transplant, and others. The medication is further segmented into antibiotics, and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

Based on the end user, it is segmented into hospitals & clinics, nephrology center, research institutes, and others.

Regional Analysis

The Americas dominate the global kidney infection market owing to the availability of technologically advanced medical devices for diagnosis and treatment of kidney infection such as dialysis machine, increasing patient population for a kidney infection, increasing government support for research & development, and high health care spending. Furthermore, increased R&D activities and the concentration of major companies have fuelled the growth of the market in this region.

The European region is exhibiting flourishing growth owing to the increasing emphasis on the development of new drugs, rising government support for research & development, and availability of funds for research. Rising number of specialty services offered by various healthcare providers in Europe also accelerate the growth of the market. For instance, developed economies such as Germany and France are increasing investment in the healthcare domain and are focusing more on the hospital infrastructure.

The Asia Pacific is the fastest growing kidney infection market owing to the presence of rapidly developing healthcare technology and high healthcare expenditure. Moreover, increasing patient population in countries such as India is likely to emerge as the fastest growing market across the globe. Furthermore, increasing demand for quality devices in the healthcare is projected to lead the use of advanced equipment, which, in turn, may speed up the market growth in this region.

However, the Middle East & Africa holds the least share of the kidney infection market due to less availability of funds, limited medical facilities, and unavailability technologically advanced medical devices.

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Global Turner Syndrome Market size and forecast, 2020-2027

Turner Syndrome is a rare chromosomal condition diagnosed in the female population. It occurs when one of the X chromosome is partially or completely missing. Women with condition are shorter than the average female and are unable to conceive due to early loss of the ovarian function. Webbed neck, a low hairline at the neck’s back, lymphedema are some of the common symptoms of the disease. Increasing prevalence of the disease and rising female population are the major factors that drives the market during the forecast period. According to the National Library of Medicine in 2017, about 1 in 2,500 new-born girls, worldwide, were affected with the Turner Syndrome, making it one of the causes of female-fetal-miscarriages and stillbirths. Moreover, according to the World Bank the female population increased from 3.60 billion in 2014 to 3.68 billion in 2016. Additionally, the increasing FDA approvals for the treatment of the diseases followed by growing biotechnology sector and increasing awareness of the women health is expected to fuel the market growth. However, high annual treatment cost followed by its related side effects like vomiting, carpal tunnel syndrome, insulin resistance/ high blood sugar, worsening of scoliosis, and others is one of the major restrains for the market growth. This along with low per capita healthcare expenditure and lack of the awareness within the low and middle income countries is projected to restrain the market growth during the forecast period.

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The market for global turner syndrome is estimated to grow at an approximate CAGR of 13.0% from 2017 to 2023.

Segmentation

The global turner syndrome market is segmented on the basis of diagnosis, treatment, and end user.

On the basis of the diagnosis, the market is categorised into physical examination, prenatal testing, karyotyping and others. The prenatal testing segment, by diagnosis, is sub-segmented into ultrasound test, amniocentesis, chorionic villus sampling, and others.

On the basis of the treatment, the market is segmented into human growth hormone therapy, oestrogen replacement therapy, progesterone replacement therapy, psychological therapy, and others.

On the basis of the end user, the market is segmented into hospitals & clinics, academic institutes, research organization, and others.

Regional Analysis

America dominates the global turner syndrome market owing to increasing adoption of new technologies and huge patient population. Additionally, rising healthcare expenditure, increasing female population followed by the presence of developed economies and healthcare sector within the region fuels the market growth.

Europe is the second largest market, in the global turner syndrome market. Rising research and development in healthcare sector, huge patient population, growing biotechnology sector are the major drivers for the market growth within the region. According to the International Trade Administration, the total turnover for the biotechnology sector in Germany reached from USD 3,280 million in 2015 to USD 3,410 million in 2016. It was also estimated that in 2016, the R&D expenditure for biotech sector was about USD 1,040 million

Asia Pacific region is the fastest growing market. Increasing awareness for women health, rising healthcare expenditures and growing healthcare sector are the major drivers for the market growth within the region during the forecast period. Moreover, the presence of the developing countries like the India and China within the region fuels the market growth. According to the Indian Brand Equity Foundation in 2017, the Indian healthcare sector was one of the fastest growing industries in India and is expected to advance at a CAGR of 22.87% from 2015-2020.

The Middle East & Africa has the least share in the global turner syndrome market. The presence of poor economies and stringent government policies, especially in the African region restrains the market growth within the region. Majority of the market in the Middle & Africa region is held by the Middle East due to a well-developed healthcare sector and huge healthcare expenditure by the presence of the developed economies like Saudi Arabia, Kuwait, and Qatar within the region.

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Global Nonallergic Rhinitis Market size and forecast, 2020-2027

Market Synopsis of the Global Nonallergic Rhinitis Market

Also known as vasomotor rhinitis, nonallergic rhinitis is a medical condition that causes chronic sneezing, and congestion. Although the symptoms of nonallergic rhinitis are similar to that of allergic rhinitis, it does not involve the immune system. This condition can be diagnosed with, physical examination, allergy test such as skin test, blood test, and imaging tests such as CT scan. Treatment includes use of nasal sprays, oral decongestants, and over-the-counter (OTC) drugs or prescription medications.

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Rising prevalence of nonallergic rhinitis, and increasing demand for diagnosis and treatment of nonallergic rhinitis are the major factors driving the growth of the market across the globe. Furthermore, increasing healthcare expenditure and overall growth of healthcare industry also influences the market growth. Splendid research in the field of immunology also boost the market. Additionally, increasing focus on the development of new medications for the treatment of nonallergic rhinitis, and increasing use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) also fuel the market growth. The growth of the market is restricted by increasing competition among key players in the market that act as a barrier of new entrants.

The global nonallergic rhinitis market is expected to grow at a CAGR of 5.3% during the forecast period.

Segments

The global nonallergic rhinitis market is segmented on the basis of diagnosis, treatment, and end user.

On the basis of diagnosis, market is categorized into physical examination, allergy testing, imaging test, and other segments. Allergy testing is further segmented into skin test and blood test. Imaging test is further segmented into nasal endoscopy, and computerized tomography (CT) Scan.

On the basis of treatment, the market is segmented into nasal sprays, NSAIDs and others.

Nasal sprays is further segmented into saline, corticosteroid, antihistamine, decongestants, and anti-drip anticholinergic.

On the basis of end user, the market is segmented into hospitals & clinics, research centers, and others.

Regional Analysis of the Global Nonallergic Rhinitis Market

America holds the first position in the market for nonallergic rhinitis owing to the rising prevalence of nonallergic rhinitis in the U.S., and consequent increase in the demand for new diagnostic and treatment services. In Americas, North America is the largest market owing to the presence of key players in the industry. As per the Warren Alpert Medical School of Brown University, the prevalence of nonallergic rhinitis has been observed to be one-third that of allergic rhinitis, affecting ~7% of the U.S. population or ~22 million people. Additionally, rising awareness about morbidity due to nonallergic rhinitis and the presence of key players in the market also influence the growth of the market.

Europe is the second largest market for nonallergic rhinitis. In Europe, there is an increasing demand for nasal sprays, and extensive research and development activities by clinical research and academic institutes for chronic diseases treatment. Germany, and France are the largest contributors to the market growth owing to an increase in the number of market players manufacturing NSAIDs, and overall growth of healthcare industry.

The market in Asia Pacific is expected to grow at the fastest pace and is driven by an increasing number of patients suffering from nonallergic rhinitis and increasing awareness about the diagnosis and treatment. India, China, and Japan are major contributors to the growth of the market. This growth is attributed to an increasing demand for nasal sprays and OTC medicines and availability of highly qualified medical personnel dedicated to the research of chronic diseases.

The Middle East & Africa also show a steady rise in the market owing to low prevalence of nonallergic rhinitis and increasing awareness about allergic and nonallergic rhinitis treatment. In the Middle East & Africa, the Middle East captures the largest market share for availability of specialty medical services and increasing expenditure on healthcare

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3D Cell Culture Market Growth, Trends and Value Chain 2020-2027

3D cell culture is a technique in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Besides, the ability of 3D cell culture to provide more physiologically relevant information and more accurate data in vivo tests has led 3D cell culture systems to become acceptable in comparison to 2D Cell culture. Many factors drive the market of 3D cell culture across the world such as an advanced technique in organ and tissue regeneration, provide drug toxicology screening and many more.

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The global 3D cell culture market has been identified as one of the fastest growing industries, owing to the varying applications of 3D cell culture in biotech and pharmaceutical industry and rising prevalence of cancer worldwide, rising approval from government bodies, and growing awareness Increasing incidence of cancer and rising demand for organs transplantation due to increasing prevalence of organ failures has majorly influenced the growth of the market.

The global 3D cell culture market is expected to grow at a CAGR of 25.50% during the forecast period 2017–2023.

Segmentation

The global 3D cell culture market is segmented on the basis of technique, product, application, and end-user. On the basic technique, it is segmented into Scaffolds Based 3D Cell Culture and Scaffold-Free 3D Cell Culture. On the basis of the product, it is segmented into Consumables and Instruments. On the basis of the application, it is segmented into cancer research, stem cell research, drug discovery, Tissue Screening & Engineering, Regenerative Medicine and others. On the basis of the end users, it is segmented into Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Research & Academic Laboratories and others.

Key Findings

The global 3D cell culture market was USD 725.15 million in 2016
Consumables are the largest segment, by product which is projected to grow at a CAGR of 25.88% during the forecast period from 2017–2023
Drug discovery is the largest segment, by application for the global 3D cell culture and expected to grow at a rate of CAGR 25.75% during the forecast period
The Pharmaceutical & Biotechnology Companies segment and is expected grow with the CAGR of 26.13% for the forecast period.

Regional Analysis

Global 3D cell culture, on the basis of region, the market is divided into the Americas, Europe, Asia Pacific and the Middle East & Africa. The Americas accounted for the largest market share of for global 3D cell culture market. This large share is majorly attributed due to the presence of major manufacturers, high rate of cancer among the population, rising need for organ donation, and various others. Europe accounts for the second largest market share, whereas Asia Pacific is expected to grow at the fastest rate with 26.17% CAGR for the forecast period. With lots of opportunity and continuously growing economies, the region is expected to be the fastest growing segment. Factors such as recent healthcare developments, improving economies, high aging population, and increased healthcare spending are influencing the growth of the market. The Middle East & Africa with less economic developments and extremely low income accounted for the least market share in 2016 but is expected to grow in coming future.

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