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Wednesday, 5 May 2021

Hearing Aids Market Size, Share, Demand, Financial Overview, Key Developments, Swot Analysis and Forecast to 2027

Market Forecast

Hearing Aids Market is expected to cross USD 10.2 Billion by 2025 at a CAGR of 7%.

Market Synopsis

The technological advancements and launch of new products are expected to fuel the global hearing aids market.

Market Influencer

Technological advancements for the development of products by hearing aids manufacturers which along with improved hearing experience also have sleek appearance promoting the use of hearing aids.

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The growth of global hearing aids market is driven by various factors such as increasing incidence of hearing loss, the launch of new products, increasing geriatric population, and raising awareness about hearing loss treatment. However, the low penetration of hearing aids and product recalls are expected to curb the growth of the global hearing aids market.

The global hearing aids market is currently dominated by several market players. The key players are involved in product launches and strategic collaborations to strengthen their market positions.

Regional Analysis

The market has been divided, by region, into Europe, the Americas, Asia-Pacific, and the Middle East & Africa. Europe is expected to be the largest market owing to the rising incidence of hearing loss and sophisticated healthcare infrastructure. The European hearing aids market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The Americas holds the second largest hearing aids market share. The hearing aids market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The hearing aids market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing awareness regarding the use of hearing aids and increasing population affected by hearing disorders, the market in Asia-Pacific is expected to be the fastest-growing. The hearing aids market in the Middle East & Africa has been divided into the Middle East and Africa and is expected to hold the least market share.

Segmentation

The global hearing aids market has been segmented based on product, product type, type of hearing loss, technology type, and distribution channel.

The market, based on product, has been divided into devices, implants, and accessories, out of which implants is the fastest-growing segment. For instance, the Australia-based manufacturer Cochlear Ltd reported a profit of USD 265 to USD 275 million in first quarter of 2019, 8% to 12% more as compared to that in the first quarter of 2018.

The global hearing aids market has been segmented, on the basis of product type, into wired and wireless. Wireless is the fastest-growing segment owing to technological advancements and product launches. For instance, Sonova, in November 2018 launched products based on SWORD (Sonova Wireless One Radio Digital) chip. The new technology allows hearing instruments to connect with electronic devices such as televisions or mobile phones.

The type of hearing loss segments of the market are sensorineural, conductive, and others. The growth of the segment is due to the high prevalence of hearing loss. For instance, in 2018, around 2 to 3 out of 1000, children in the US are born with a hearing loss in one or both ears.

The technology type segment of the market is segmented as digital hearing aids and analog hearing aids. The digital hearing aids segment is expected to be both, the largest shareholder and the fastest-growing segment owing to its advantages over analog counterparts.

The distribution channel segment is classified into retail stores, E-commerce, and others. The E-commerce segment is expected to be the fastest-growing segment owing to ease of access to products for customers.

Key Players

Some of the key players in the global hearing aids market are Sonova (Switzerland), Cochlear Ltd. (Australia), GN Store Nord A/S (Denmark), Sivantos Pte. Ltd. (Singapore), Arphi Electronics Private Limited (India), Demant A/S (Denmark), Starkey (US), WIDEX INDIA PRIVATE LIMITED (Denmark), Zounds Hearing (US), SeboTek Hearing Systems, LLC (US), Audina Hearing Instruments, Inc. (US), and Microson (Spain).

Alpha-1 Antitrypsin Deficiency Treatment Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

Market Forecast

Global Alpha-1 Antitrypsin Deficiency Treatment Market is expected to cross USD 2,914.7 Million by 2025 at a CAGR of 10.50%.

Growing product pipeline for alpha-1 antitrypsin drugs and rising prevalence of alpha-1 antitrypsin deficiency are set to drive the market growth for alpha-1 antitrypsin deficiency treatment. Approximately 100,000 people in the US are known to suffer from alpha-1 antitrypsin deficiency.

Rising awareness regarding the alpha-1 antitrypsin deficiency is expected to drive the growth of the global alpha-1 antitrypsin deficiency treatment market.

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The market is dominated by numerous established players. The key players are involved in product launches, strategic collaborations, and awareness programs to strengthen their market positions. For instance, in November 2018, Grifols S. A. launched the AlfaCare therapy program for training and counseling of patients diagnosed with alpha-1 antitrypsin deficiency.

Market Influencer

The prevalence of alpha-1 antitrypsin deficiency (AATD) is increasing, which is directly responsible for the growth of the global alpha-1 antitrypsin deficiency treatment market. Strategic initiatives, mergers & acquisitions, partnerships, agreements, product launches, government approvals, and expansion of manufacturing facilities by major competitors are expected to further boost market growth during the forecast period.

Segmentation

By Drugs:

Alpha-1 Proteinase Inhibitor: The segment is expected to hold the largest Alpha-1 Antitrypsin Deficiency Treatment market share as it is the only treatment for AATD, which protects the patient from more lung damage.
Bronchodilators: These are used for the treatment of respiratory disorders associated with AATD.
Steroids: These are used specifically for the treatment of chronic obstructive pulmonary disease, which affects the patient along with AATD.
Others: Other treatment options include antibiotics for infections and jaundice associated with AATD and oxygen therapy.

By Route of Administration:

Oral: The segment is expected to hold the largest market share.
Intravenous: The segment is expected to grow at the fastest CAGR.
Inhalation: This route of administration is used specifically for the administration of corticosteroids for treating breathing disorders.
Others: Subcutaneous and intramuscular routes of administration.

By Distribution Channel:

Hospital Pharmacy: The rise in the number of hospitals is likely to be responsible for the largest market size.
Retail Pharmacy: These fulfill the requirement of drugs that are needed for treatment at home.
Online Stores: The fastest-growing segment owing to increase in number of online pharmacies.

By Region

Americas: The region holds the largest share of the market. The market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada.

Europe: The European alpha-1 antitrypsin deficiency treatment market has been classified as Western Europe and Eastern Europe. The Western European market has further been categorized as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

Asia-Pacific: The market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The Asia-Pacific alpha-1 antitrypsin deficiency treatment market is projected to be the fastest-growing during the forecast period.

Middle East & Africa: The market in the Middle East & Africa has been divided into the Middle East and Africa.
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Orthokeratology Lens Market Size, Share, Demand, Financial Overview, Key Developments, Swot Analysis and Forecast to 2027

Global Orthokeratology Lens Market is expected to register a CAGR of 7.4% to reach USD 3,857.8 Million till 2025.

Orthokeratology is also known as ortho-k, corneal refractive therapy (CRT), and overnight vision correction therapy. It is a non-surgical method used to correct refractive errors by reshaping the curvature of the cornea to improve object visibility. This procedure is a temporary treatment method used for the correction of myopia, hypermetropia, and other eye-related problems.

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The growing prevalence of refractive errors across the globe, advancements in the field of ophthalmology over the past couple of decades and low cost compared to laser-assisted in situ keratomileuses (LASIK) treatment is expected to enhance the market growth. However, the availability of alternative treatment methods and risk associated with orthokeratology are projected to curb the growth of the market.

Market Dynamics

A rise in the number of individuals with refractive errors such as myopia, hypermetropia, astigmatism, and presbyopia increases the demand for innovative treatment methods. Myopia is reported as the most common disorder affecting a large number of populations worldwide. The World Health Organization 2018 fact sheet estimated that approximately 1.3 billion people were living with some form of vision impairment. It also reported that 188.5 million patients have a mild vision impairment, 217 million people have moderate to severe vision impairment, and 36 million people are blind, globally. Such a vast population suffering from eye problems boosts market growth during the forecast period.

Segmentation

The global orthokeratology lens market, by material, has been segmented into silicone acrylate, fluorosilicone acrylate, and fluorocarbon acrylate. On the basis of application, the global orthokeratology lens market has been segmented into myopia and hyperopia. Based on end user, the market has been segmented into hospitals and ophthalmic clinic.

Regional Analysis

The global orthokeratology lens market, based on region, is divided into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.

The Americas is expected to hold the largest share of the global orthokeratology lens market. The growth of the Americas can be attributed to its rising geriatric population and increasing ophthalmological disorders, causing an increased need for diagnosis and therapeutics.

Asia-Pacific is expected to account for the second-largest orthokeratology lens market share during the forecast period. The factors responsible for market growth in this region are the rising patient population of people with eye disorders, availability of advanced treatment facilities, increasing healthcare expenditure, and the introduction of advanced therapies into the market along with the presence of good healthcare infrastructure. According to the Asian Development Bank, the elderly population in Asia is projected to reach nearly 923 million by 2050.

Europe is estimated to be growing at the fastest pace in the global market due to the increasing cases of eye disorders and increasing government initiatives are driving the growth of the market. According to reports published by the United Kingdom Statistics Authority, in 2015, around 15,900 people were registered as visually impaired.

The orthokeratology lens market in the Middle East & Africa is expected to exhibit the least growth in the global orthokeratology lens market due to factors such as limited access to healthcare affordability issues.

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Tuesday, 4 May 2021

Sentinel Node Biopsy Market Growth, Trends and Value Chain 2020-2027

Synopsis of the Global Sentinel Node Biopsy Market

A sentinel lymph node biopsy is a medical procedure, which involves identification, removal, and examination of the lymph node to verify the presence of cancer cells. Lymph nodes are a part of the lymphatic system which is found throughout the body and is connected to the lymph vessels. Breast cancer, melanoma, colon cancer, esophageal cancer, head and neck cancer, non-small cell lung cancer, stomach cancer, thyroid cancer are various indications for biopsy. The procedure helps the healthcare provider to determine the stage of cancer, its metastasis in order to plan a line of treatment for the patient.

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Rising prevalence of various types of cancer such as breast cancer, melanoma, colon cancer and growing emphasis on women healthcare are the major drivers for the growth of the market. Additionally, increasing number of health problems women further fuel the market growth. Demand for diagnosis and treatment of breast cancer and the technologically advanced medical device is found to be increasing across the globe. Furthermore, increasing healthcare expenditure and overall growth of healthcare industry also influence the market growth. Extensive research in the field of reproductive health and diseases also boost the market. Increasing demand for new products and accessories with advent of technology in the healthcare industry also fuels the growth of the market across the globe. However, various factors restrained the market growth such as complications associated with the biopsy and unawareness among women.

The global sentinel node biopsy market analysis is expected to grow at a CAGR of 5.1% during the forecast period.

Segments

The global sentinel node biopsy market is segmented on the basic product, indication, and end user.

On the basis of product, market is segmented into breast localization wire, tissue marker, gamma probe, drainage catheter, and others

On the basis of indication, the market is segmented into breast cancer, melanoma, colon cancer, esophageal cancer, and others.

On the basis of the end user, the market is segmented into hospitals & clinics, diagnostic centers, and others.

Intended Audience

Medical Device Manufacturers
Medical Device Suppliers
Medical Research Laboratories
Healthcare IT Companies
Research and Development (R&D) Companies
Market Research and Consulting Service Providers
Potential Investors

Regional Analysis of the Global Sentinel node biopsy Market

America captures the first position in the market for sentinel node biopsy whose market is driven by increasing number of women suffering from breast disorders and rising prevalence of breast cancer in the U.S. and Canada. Furthermore, the market is also driven by the availability of technologically advanced medical devices and quality care in healthcare institutes. In Americas, North America is the major market due to increasing number of market players offering biopsy devices and instruments. As per the American Cancer Society, in 2015, there were 231,840 new cases of breast cancer, and till March 2017, there were 3.1 million women with a history of breast cancer in the U.S. As per the National Cancer Institute, 2016, in the U.S. around 1,685,210 new cases of cancer were diagnosed and in 2014, around 15,780 children and adolescents ages 0 to 19 were diagnosed with cancer and 1,960 died of the disease.

In Europe, sentinel node biopsy market shows better growth opportunities governed by the ongoing research and development activities in the field of oncology. In Europe, there is an increasing demand for medical devices and availability of funds for research and development activities in the reproductive health. Germany acquires the first position the European market owing to an increasing demand for cancer diagnosis. France and U.K secure second and third position are respectively owing to the availability of tertiary care facilities in these countries and rising healthcare expenditure.

The Asia Pacific is the fastest growing region in the market whose growth is determined by the presence of highly skilled workforce and increasing demand for biopsy procedures in hospitals and specialty care centers. India and China exhibit enormous growth opportunities owing to ever increasing the prevalence of chronic diseases, increase in a number of women suffering for reproductive disorders, and increasing expenditure on surgical procedures industry by key players in developing economies throughout the Asia Pacific.

In the Middle East, Saudi Arabia and the United Arab Emirates are the major countries holding the largest share in the market. Increase in the number of specialty care services and rising demand for diagnosis of various types of cancer are the key drivers of the market. Africa exhibits slow growth owing to limited penetration of technology in this region and unawareness about sentinel node biopsy.

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Key Players in the Global Sentinel Node Biopsy Market

Some of the key players in this market are Devicor Medical Products, Inc., part of Leica Biosystems. (Germany), C. R. Bard, Inc. (U.S.), INTRAMEDICAL IMAGING LLC (U.S.), Hilfe Engineering Corporation (India), Surgic Eye (Germany), KUB Technologies, Inc. (U.S.), Navidea Biopharmaceuticals, Inc.(U.S.) and others.

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Hematocrit Test Market Size, Share, Demand, Financial Overview, Key Developments, Swot Analysis and Forecast to 2027

Also known as packed-cell volume (PCV) test, hematocrit test is used to measure the percentage of Red Blood Cells (RBCs) in the blood. The major function of the RBCs is to carry blood throughout the body. The test is usually performed to diagnose various diseases such as anemia, leukemia, lymphoma, congenital heart disease, and others. The test determines the elevation in the percentage of normal RBCs which is 38.8%-50% in men and 34.9%-44.5% in women. The hematocrit test is one of the tests included under complete blood count (CBC) test.

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Cardiovascular diseases, cancer, and kidney diseases are increasing the economic burden of various developing and developed nations across the globe. The market for hematocrit test is driven by rising prevalence of chronic diseases such as cardiovascular diseases, diabetes, and others along with changing lifestyle, and increasing demand for diagnostic devices for cardiovascular diseases. However, limited number of trained personnel has restrained the growth of the market. However, the high cost of diagnosis and treatment of cardiovascular diseases also restrains the growth of the market. As per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the overall prevalence of Chronic Kidney Disease (CKD) in the general population across the globe is nearly 14%. However, the growth of the market is restrained by the inaccurate or misleading result of the test and unawareness about hematocrit test in the diagnosis of the disease.

The global hematocrit test devices market is expected to grow at a CAGR of 4.5% during the forecast period.

Segments

The global hematocrit test market is segmented on the basis of product, indication, devices, and end-user.

On the basis of product, the market is segmented into the analyzer, hematocrit test meter, and others.

On the basis of indication, the market is segmented into anemia, leukemia, lymphoma, congenital heart disease, kidney tumor, and others.

On the basis of the end-user, the market is segmented into hospitals & clinics, diagnostic centers, and others.

Intended Audience

Medical Device Manufacturers
Medical Device Suppliers
Medical Research Laboratories
Research and Development (R&D) Companies
Market Research and Consulting Service Providers
Potential Investors

Regional Analysis of the Global Hematocrit Test Market

The global hematocrit test market consists of four major regions namely, the Americas, Europe, Asia Pacific and the Middle East & Africa, with the Americas capturing the largest market share. The growth of the market is attributed to an increase in the demand for diagnostic procedures, and rising importance of hematology testing for the diagnosis of various chronic diseases. North America accounts for the major share in the American hematocrit test market which is attributed to extensive use of hematocrit test with other diagnostic tests. According to the Center for the Disease Control and Prevention (CDC), as of 2012, nearly half of all the adults, 117 million population in the U.S. had one or more chronic health conditions. One in four adults were diagnosed with two or more chronic health diseases.

In Europe, the growth of the market is driven by increasing demand for diagnostic devices and instrument in hospitals and diagnostic centers. Germany, the U.K, and France are the major contributors to the growth of the market owing to an increase in the number of key players engaged in the manufacturing of medical devices and instruments and rising expenditure in research and development by these major economies. Additionally, well-developed healthcare sector, ever-increasing patient population and high healthcare expenditure by the European nations fuel the market growth.

The Asia Pacific is expecting the fastest growth in the market due to the flourishing growth of healthcare industries in developing economies such as India. Additionally, the ever-increasing prevalence of kidney diseases and cardiovascular diseases and rising demand for quality devices in the healthcare sector is expected to lead the use of advanced equipment, which, in turn, may speed up the market growth in the region. Rising geriatric population with chronic diseases further creates the economic burden on the developing nations thereby accelerating the market growth.

The Middle East & Africa hold the least share in the market. The market in this regions exhibits steady growth owing to an increase in the demand for the diagnostic and treatment services. In the Middle East and Africa, the United Arab Emirates (UAE) hold the largest market share owing to the availability of diagnostic and treatment services. Africa shows slow growth due to low technology penetration in developing countries.

Key Players in the Global Hematocrit Test Market

Some of the key players in this market are Abbott (U.S.), F. Hoffmann-La Roche Ltd (Switzerland), Siemens AG (Germany), Beckman Coulter, Inc. (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Horiba, Ltd. (Japan), Mindray Medical International Limited (China), Boule Diagnostics AB (Sweden), Nihon Kohden Corporation (Japan), Sysmex Corporation (Japan), and others.

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Dravet syndrome Market: Recent Industry Trends and Projected Industry Growth, 2020– 2027

Market Scenario:

Dravet syndrome is a rare genetic epileptic encephalopathy that begins during the first year of life in an otherwise healthy infant. According to the National Center for Advancing Translational Sciences, in 15% to 25% cases of the Dravet syndrome, a family history of epilepsy or febrile seizures exists. It is also reported that 85% cases of Dravet syndrome originated due to a mutation in the SCN1A gene.

It is noted that development of new drugs and therapies, and rising R&D expenditure are propelling the growth of the market. In recent years, Dravet syndrome has gained significant attention due to the upcoming drugs for its treatment. For instance, on February 06, 2018, Zogenix, Inc. received breakthrough therapy designation from FDA for its product, ZX008. The drug is specialized for the treatment of Dravet syndrome and its related complications.

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Various other factors such as unmet medical needs, increasing government assistance, rising healthcare expenditure in the developed countries, improving regulatory framework, increasing adoption rate, and rising funding and reimbursement policies are continuously contributing to the growth of the global Dravet syndrome market.

Despite these drivers, there are some issues associated with Dravet syndrome market. The side effects of drugs and other therapeutic agents, lack of awareness in the developing countries, and poor healthcare system in low and middle-income countries, may hinder the growth of the market.

It is estimated that the Dravet syndrome treatment industry is expected to grow at a CAGR of 8.5% during the forecast period of 2017-2023.

Intended Audience:

Pharmaceutical Companies
Research and Development (R&D) Companies
Government Research Institute
Academic Institutes and Universities

Key Players:

Some of key the players in the global dravet syndrome market are Biocodex, Biscayne Neurotherapeutics, Cyberonics, Inc., Epygenix Therapeutics, Inc., GW Pharmaceuticals, plc, INSYS THERAPEUTICS, INC., OPKO Health Inc., Ovid Therapeutics, PTC Therapeutics, Sage Therapeutics, Takeda Pharmaceutical Company Limited, Thermo Fisher Life Technologies, Xenon Pharmaceuticals, Zogenix, Inc, and others.

Segmentation:

The global Dravet syndrome market is segmented on the basis of the type of seizures, diagnosis, treatment & management, and end-user.

On the basis of the type of seizures, the market is classified as myoclonic seizures, atonic seizures, partial seizures, absence seizures, tonic clonic seizures, photosensitive seizures, and others.

On the basis of the diagnosis, the market is classified as magnetic resonance imaging (MRI), electroencephalography (EEG), SCN1A testing, and others.

On the basis of the treatment & management, the market is classified as seizure medications, ketogenic diet, vagus nerve stimulation (VNS), and others. The seizure medications segment is further classified into clobazam, stiripentol, sodium valproate, and others.

On the basis of the end-user, the market is segmented into pharmaceutical companies, hospitals, diagnostic laboratories, academic and research institutes, and others.

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Parathyroid Disorders Market Size, Share, Demand, Financial Overview, Key Developments, Swot Analysis and Forecast to 2027

Parathyroid glands produce and secrete a parathyroid hormone which is involved in regulation of calcium and phosphorus metabolism. Hyperparathyroidism and Hypoparathyroidism are the two most common parathyroid disorders. The hyperparathyroidism is characterized by an excessive secretion of parathyroid hormone. The most common signs and symptoms of the disorder include kidney stones, bone and joint pain, fragile bones, weakness.

According to a study published in the Turkish Journal of Trauma and Emergency Surgery in 2016, it is found that hyperparathyroidism is the third most common clinical endocrine disorder with a prevalence between 0.1–1.0%, and an incidence of around 28 cases per 100,000 individuals. It also reported that the incidence rate is highest between 50 and above age group i.e. the condition is affecting 2% of the population aged 55 years or older.

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Notably, rising prevalence of parathyroid disorders and growing geriatric population are the key factors driving the parathyroid disorders market.

Various other factors such as increasing incidences of parathyroid disorders, increasing government assistance, rising healthcare expenditures, improving regulatory framework, and rising funding and reimbursement policies are continuously contributing to the growth of the global parathyroid disorders market. According to the data suggested by Eurostat, it is observed that among the EU Member States, the highest value of healthcare expenditure was recorded in Germany in 2014 i.e. EUR 321 billion, which is further followed by France with EUR 237 billion, and the United Kingdom with EUR 223 billion.

Despite these drivers, there are some issues associated with parathyroid disorders market. Some of the challenges include less research and development funding, side-effects of treatment, the presence of misbranded and spurious drugs, expiration of patented drugs and poor healthcare system in low and middle-income countries may hinder the growth of the market to an extent.

The parathyroid disorders market insights by MRFR expected to grow at a CAGR 6.5% during the forecast period of 2017-2023.

Intended Audience:

Pharmaceutical Companies
Research and Development (R&D) Companies
Medical Device Companies
Diagnostic Laboratories
Government Research Institute
Academic Institutes and Universities

Segmentation

The global parathyroid disorders market is segmented on the basis of type, diagnosis, treatment, and end-user.

On the basis of the type, the market is classified as hyperparathyroidism (HPT), parathyroid cancer, and hypoparathyroidism. The hyperparathyroidism is further segmented into primary hyperparathyroidism, secondary hyperparathyroidism, and tertiary hyperparathyroidism.

On the basis of the diagnosis, the market is classified as blood tests, imaging tests, and urine tests. The imaging tests is further sub-segmented into CT or CAT (computed axial tomography) scans, MRI (magnetic resonance imaging) scans, X-ray, ultrasound, bone density test, and sestamibi scan.

On the basis of the treatment, the market is classified as surgery, radiation therapy, drugs, and others. The drugs segment is further sub-segmented into calcimimetics, hormone replacement therapy, and bisphosphonates.

On the basis of the end-user, the market is segmented into hospitals & clinics, diagnostic centers, drug stores, pharmacies, and others.

Regional Analysis:

The Americas dominate the global parathyroid disorders market owing to the rising prevalence of parathyroid disorders and high healthcare expenditure. According to the Centers for Disease Control and Prevention in 2015, the total health expenditure in the United States was reported to be USD 3.2 trillion and hospital care accounted for a share of 32.3%.

Europe holds the second position in the parathyroid disorders market. It is expected that the support provided by the government bodies for research & development and improvement in the reimbursement policies in the healthcare is likely to drive the market of the European region.

The Asia Pacific region is the fastest growing parathyroid disorders market owing to a huge patient pool and developing healthcare technology. Healthcare expenditure is also improving in various Asia Pacific countries. According to the Australian Institute of Health and Welfare in the years 2015-2016, the total health expenditure was USD 170.4 billion, which is 3.6% higher than the expenditure of 2014-2015.

The Middle East & Africa holds the least market share due to lack of technical knowledge and poor medical facilities.

Key Players

Some of the key players in the global parathyroid disorders market are Abbott Laboratories, Alcon Laboratories, Inc., Amgen Inc., Bayer Healthcare, Becton, Dickinson and Company, Eli Lilly, Ethicon, Inc., Genentech, Medtronic, Merck, Mylan Laboratories, Novartis, Novo Nordisk, Pfizer, Roche, Smith & Nephew plc, Stryker, Teva Pharmaceutical Industries Ltd., Zimmer Biomet Holdings, Inc., and others.

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