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Tuesday, 18 May 2021

Dental Lasers Market to Witness Widespread Expansion During 2020-2027

Market Scenario

The global Dental Lasers Market is estimated reach USD 2.3 billion by 2023 with a CAGR of 5.2% during the forecast period (2017-2023).

The term “LASER” stands for ‘Light Amplification by the Stimulated Emission of Radiation’. Lasers emit a thin and concentrated beam of light, producing a thermal output. This thermal output has been used in the dentistry for endodontic treatment, oral surgery, implantology, peri-implantitis, periodontics, and others.

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From the past few years, the dental laser market has expanded with a steady CAGR. Factors such as, increasing prevalence of dental diseases, rising dental healthcare expenditure, growing R&D by the major market players, and increasing dental tourism are estimated to drive the market during the forecast period. Dental caries is a common chronic tooth tissue disease and effects ~90% of the world population (once in the lifetime). In the presence of such high prevalence of dental caries, demand of related therapeutics has increased. It is reportable that dental caries can be removed effectively by the application of dental lasers. Fast procedure and minimal invasion are some of the advantages associated with caries removal by dental lasers.

However, factors such as high cost of dental laser, changing reimbursement policies, lack of skilled work-force and awareness in the developing economies restraints the market growth. A sophisticated laser system is estimated to cost about USD 300, 000 to USD 500,000 or more.

Segmentation

The global dental lasers market is segmented based on product, application, and end users.

The dental lasers market, by product is segmented into soft tissue dental lasers and all tissue dental lasers. The soft tissue dental lasers is sub-segmented into diode lasers systems, CO2 laser systems, and Nd:YAG laser systems. The all tissue dental lasers segment is divided into Er:YAG laser systems, and Er,Cr:YSGG laser systems.

By application, the market is segmented into endodontic treatment, oral surgery, implantology, peri-implantitis, periodontics, and others.

The dental lasers market, by end user is segmented into hospitals & clinics, ambulatory surgical units, academic & research organizations.

Based on region, the global dental lasers market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas is sub-segmented into North America and Latin America. The North American region is further segmented into the US and Canada. The European region is divided into two, namely, Western Europe and Eastern Europe. Western Europe is further classified into Germany, Italy, France, the UK, Spain, and the rest of Western Europe. The Asia-Pacific region is sub-segmented into Japan, China, India, Australia, the Republic of Korea, and the rest of Asia-Pacific. The Middle Eastern and African region is sub-segmented into the United Arab Emirates, Saudi Arabia, Oman, Kuwait, Qatar, and the rest of the Middle East and Africa.

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Global Substance Abuse Treatment Market size and forecast, 2020-2027

Global substance abuse treatment market is expected to grow significantly over the forecast period. It is projected to grow at a CAGR of 11.6% over the forecast period.

Substance abuse refers to the harmful use of psychoactive substances, including alcohol and illicit drugs.

Increasing trends of cigarette smoking in teenagers is one of the prominent factors driving the Substance Abuse Treatment market. According to the 2015 study published in the Clinical and Translational Investigation journal, More than 60% of individuals start smoking at the age of 13 and more than 90% individuals start smoking before reaching 20 years. It is also reported that 5.8% of the Mexican population comprises adolescents between 13 and 15 years. Of them, 42.8% tried a cigarette at some point in their life.

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Various other factors such as increasing incidence of drug addiction, technological advancement in the diagnostics industry, rising patient awareness about substance abuse treatment and improvement in treatment rates and healthcare infrastructure are also expected to propel the growth of the market.

However, poor treatment compliance in some countries and reluctance of individuals for accessing treatment can hamper the market growth over the forecast period.

Segmentation

The global substance abuse treatment market is segmented based on abuse type, treatment type, end user, and region.

The global market for substance abuse treatment, by abuse type is segmented into alcohol dependence, tobacco/nicotine addiction, and drug abuse. The drug abuse segment is anticipated to hold the largest market share owing to the increasing addiction of opioid.

The market, by treatment type, is segmented into alcohol addiction treatment, tobacco/nicotine addiction treatment, and drug abuse treatment. The alcohol addiction treatment segment is further classified as disulfiram, acamprosate, and naltrexone. The tobacco/nicotine addiction treatment segment is further classified as nicotine replacement treatment, and non-nicotine medication. The nicotine replacement treatment segment includes nicotine patch, nicotine gum, nicotine lozenge, nicotine spray, and nicotine inhaler. The non-nicotine medication segment includes bupropion, and varenicline. The drug abuse treatment segment is further classified as methadone, buprenorphine, and naltrexone.

Based on end user, the market is segmented into outpatient treatment centres, residential treatment centres, and inpatient treatment centres.

In the current scope of the study, the above-mentioned segments are covered into the four global regions, namely the Americas, Europe, Asia-Pacific and the Middle East & African region.

The substance abuse treatment market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European substance abuse treatment market has been segmented into Western Europe and Eastern Europe. Western Europe has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The substance abuse treatment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The substance abuse treatment market in the Middle East & Africa has been segmented into the Middle East and Africa.

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Monday, 17 May 2021

Viral Vector Manufacturing Market Growth, Trends and Value Chain 2020-2027

Market Scenario:

Global viral vector manufacturing market is expected to grow significantly over the forecast period. It is projected that the global viral vector manufacturing market is expected to register a CAGR Approx. 22.65% with an expected market value of USD 319 million during the forecast period of 2018–2023. Gene therapy is one of the preferred treatment options for most chronic diseases, involving insertion of a functional copy of a gene into a defective cell. Viral vector methods are used in effective transfer of therapeutic gene into the target cells. Viral vectors used in gene therapy include retroviral vectors, adenoviral vectors and adeno-associated viral vectors.

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Numerous factors such as rise in number of clinical trials, increase in the number of gene therapy candidates, and growing necessity for an effective mode of disease treatment are expected to drive the growth of the market. Also, the characteristics of viral vectors such as ability to express therapeutic genes efficiently, and non-pathogenic nature fuels the growth of the market. Moreover, several companies involved in the development of viral agent-based products often seek support in terms of strategic collaborations and acquisitions with contract service providers to deliver a clinical grade product. This is mainly because of the limited availability and complexity of platform and technologies used for vector designing, production, packaging, and release testing. For example, in December 2017, Merck announced a commercial supply agreement to manufacture viral vectors for Bluebird Bio, Inc. for its use in potentially transformative gene therapies. This move will accentuate the life science business of Merck as a leading contract manufacturing organization and commercial provider of viral vectors for gene therapy.

However, high cost of gene therapies and possible mutagenesis may hamper the market growth during the assessment period.

Segmentation:

The global viral vector manufacturing market has been segmented into type, disease, application, and end-user.

The market, on the basis of type, has been segmented retroviral vectors, adenoviral vectors, adeno-associated viral vectors, and other viral vectors.

The segment, by retroviral vectors is anticipated to be the largest segment. Retro viruses contain an enzyme reverse transcriptase which allows the integration into the host genome. This has increased the usage of retroviral vectors in various treatment options, whereas the adenoviral vectors segment is estimated to be the fastest growing segment owing to their increased use in the in-vivo and in-vitro experiments.

The market, by retroviral vectors, has been further segmented into lentiviral vectors and gamma-retroviral vectors.

The market, by disease, has been segmented into cancer, genetic disorders, infectious diseases, and others.

The market, by application, has been segmented into gene therapy and vaccinology.

The market, by end-user, has been segmented into pharmaceutical and biotechnology companies, research institutes, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The viral vector manufacturing market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European viral vector manufacturing market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The viral vector manufacturing market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The viral vector manufacturing market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key players:

FUJIFILM Diosynth Biotechnologies U.S.A., Inc., Sanofi, Lonza, Merck KGaA, GENERAL ELECTRIC COMPANY, Oxford BioMedica, Spark Therapeutics, Inc., uniQure N.V., FinVector Vision Therapies, Brammer Bio, Cell and Gene Therapy Catapult, Cobra Biologics, REGENXBIO Inc., and Kaneka Eurogentec S.A. are some of the key players in the global viral vector manufacturing market.

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Genitourinary Drugs Market Growth, Trends and Value Chain 2020-2027

Market Scenario

The global genitourinary drugs market is accounted for USD 28,200 million expected and expected to register CAGR ~1.65% during the forecast period (2018–2023).

Genitourinary disorders are caused by damage to urinal or genital part of the human body. Kidney, bladder, ureter and urethra are parts of genitourinary system, genitourinary drugs are used to treat the medical complications caused to these parts. The rising prevalence of genitourinary disorders, increasing number of pipeline drugs, and technological advancement in genitourinary diagnosis are expected to drive the growth of the market. According to the U.S. National Library of Medicine more than 480 clinical trials are lined up for treatment of urinary tract infection.

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Health Information Center, Moreover, rising R&D spending and collaborative strategies adopted by the top players such as licensing and agreements are contributing to the growth of the market. For instance, in October 2018, Novartis AG signed a licensing agreement with Boston Pharmaceuticals for manufacturing and marketing of its three anti-infective products LYS228, IID572, and MAK181.

The increasing emergence of counterfeit drugs, rising generics drug competition, and high number of patent expirations may hamper the growth of the market during the assessment period.

Segmentation

The global genitourinary drugs market has been segmented on the basis of disease, product, and end-user.

On the basis of disease, the market has been classified urinary tract infections, erectile dysfunction, urinary incontinence & overactive bladder, kidney/renal cancer, genitourinary cancer, bladder cancer, bladder cancer, cervical cancer, sexually transmitted diseases, interstitial cystitis, hematuria, ovarian cancer, prostate cancer, and others.

The product segment has been divided into urologicals, hormonal therapy, gynecologicals, and anti-infectives.

The market, by end-user, has been segmented into hospitals, clinics, super specialty centers, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The genitourinary drugs market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European genitourinary drugs market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The genitourinary drugs market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The genitourinary drugs market in the Middle East & Africa has been segmented into the Middle East and Africa.

Regional Market Summary

The Americas are likely to dominate the global genitourinary drugs market owing to the rising prevalence of genitourinary disorders in aging population, increase in the healthcare expenditure, and the presence of a well-established healthcare system. According to the National Kidney Foundation, Urinary tract infections (UTIs) are responsible for nearly 10 million doctor visits each year and approximately 20% women suffer from UTI at least once in a life.

The European market is expected to be the second-largest genitourinary drugs market. The market growth in this region can be attributed to the increasing research and development, rise in number of chronic diseases such as diabetes, and government initiatives for the development of healthcare sector. According to the International Diabetes Foundation, diabetes is major health concern in European region and in 2017, approximately 9.1% of total European population was suffering from diabetes.

Asia-Pacific is expected to be the fastest-growing genitourinary drugs market during the forecast period owing to the increasing geriatric production along with rise in number of genitourinary disorders, rising investments in healthcare and expansions by market players in the region. According to United Nations, Department of Economic and Social Affairs, in 2016, 12.4% of total population in Asian countries was 60 year or older.

The market in the Middle East & Africa is expected to hold the smallest share of the global genitourinary drugs market due to lack of technical knowledge, undeveloped healthcare sector, and poor medical facilities.

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Cell Harvesting Market to Witness Widespread Expansion During 2020-2027

The global cell harvesting market is expected to grow significantly over the forecast period. It is estimated that the global cell harvesting market is expected to register a CAGR of Approx. 8.75% with an estimated market value of USD 209.5 million during the forecast period from 2018 to 2023. Cell harvesting is performed by separating the cell culture from the growing medium, involving techniques such as centrifugation, microfiltration, and depth filtration.

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Numerous factors such as an increase in chronic infections and diseases, the rapid growth of the biotechnology and pharmaceutical industries, and rising research in regenerative medicines are expected to drive the growth of the market. Moreover, the cost-effectiveness, ease of use, the durability of harvesters, technological advancements, and design development of cell harvester devices fuel the growth of the market. Several companies are also involved in new product launches to strengthen their position in the market. For instance, in September 2018, AVITA Medical, a global regenerative medicine company, announced that the US Food and Drug Administration (FDA) approved the Company’s Premarket Approval (PMA) application to market the RECELL Autologous Cell Harvesting Device (RECELL System). This device helps to treat severe burns in patients of 18 years and older.

Key players:

ads-tec GmbH, Argos Technologies, Inc., Arthrex, Inc., Avita Medical, Bertin, connectorate, Cox Scientific, hynoDent AG, PerkinElmer Inc., Scinomix, Teleflex Incorporated, and TERUMO CORPORATION are some of the key players in the global cell harvesting market.

Intended Audience

Pharmaceutical companies
Biotechnology companies
Cell harvester vendors
Research and Development (R&D) companies
Government research institutes
Academic institutes and universities

However, the technical complexity of harvesters, coupled with ethical issues related to embryonic stem cell research may curb the growth of the market. Stringent government regulations and mandatory licensing rules may also hamper the market growth during the assessment period.

Market Segmentation:

The global cell harvesting market has been segmented into product type, application, and end user.

The market, on the basis of product type, has been segmented into manual cell harvesters and automated cell harvesters.

The manual cell harvesters segment is estimated to hold the largest share owing to the high preferability of manual cell harvesters, whereas the automated cell harvesters segment is expected to be the fastest growing segment due to increased awareness and rise in the use of automated technologies in devices.

The market, by application, has been segmented into biopharmaceutical application, stem cell research, and others.

The market, by end user, has been segmented into pharmaceutical companies, biotechnology companies, research institutes, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East and Africa.

Regional Market Summary

Geographically, the Americas is anticipated to dominate the global cell harvesting market owing to a well-developed healthcare sector and growing healthcare expenditure. For instance, according to the data published by the Committee for a Responsible Federal Budget in May 2018, the US spent about USD 3.5 trillion, or 18% of its Gross Domestic Product (GDP) on health expenditures, which accounted for more than twice the average among developed countries in 2017. Additionally, many companies in this region focus on the innovation of new treatment options, thus being a lucrative option for the growth of the market in this region.

Europe is expected to hold the second largest position in the global cell harvesting market. The market growth in this region owes to the availability of funds for research. For instance, according to the data published by the National Institute of Health Funding (NIHR) in 2016, funding of EUR 928 million was announced for new NIHR Biomedical Research Centers (BRC) and NIHR Clinical Research Facilities (CRF) for five years starting from April 2017.

Asia-Pacific is anticipated to be the fastest growing region in the market due to the presence of a huge patient population and continuously developing economies.

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Swollen Knee Treatment Market Excessive Growth Opportunities Estimated to be Experienced 2020-2027

The global swollen knee treatment market size is expected to register a significant growth during the forecast period (2018–2023).

Knee swelling or occasionally mentioned as “water on the knee” is a condition where excess fluid gets accumulated in an around the knee joint. This conditions in medical terms are referred to as “knee effusion”. The swollen knee can result due to injuries such as torn ligament, cartilage tear or broken bones. The increasing number of geriatric populations followed by the rising frequency of musculoskeletal diseases, a growing number of surgeries undertaken is projected to grow the global swollen knee treatment market. The operating procedure of knee replacement is inclusive of various steps taken to implant the artificial device and replacement of the damaged knee.

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The swollen knee treatment market is anticipated to grow due to several factors such as the growing rate of elderly aged diseases like obesity, arthritis, osteoporosis, diabetes and sports-related injuries. Contrary, due to existing and upcoming advance technologies such as minimally invasive surgery and improved implant supplies are making it more broadly accepted even by the younger population.

In spite of being a widely used technique for curing extremely debilitating diseases, such as rheumatoid arthritis, the global swollen knee treatment market is confronting some challenges such as financial slowdown which is avoiding the growth of the market. Other growth restraining factors of the global swollen knee treatment market are intense competition, huge surgical cost, growing awareness for some non-surgical treatment methods such as exercises, shoe inserts, walking aids, weight loss programs, and painkiller medicines.

Segmentation

The global swollen knee treatment market has been segmented on the basis of type and end-users.

On the basis of type, the market has been classified as medications, patient-controlled analgesia (PCA) pumps, nerve blocks, liposomal bupivacaine, and surgery. The medications have been segmented into opioids and corticosteroids and others. The surgery is segmented into arthrocentesis, arthroscopy and knee replacement. The knee replacement is further segmented into total knee replacement, unicompartmental knee replacement, and others.

On the basis of end-users, the market has been classified as hospitals, clinics, ambulatory surgery centers, and others.

On the basis of region, the market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas has been further segmented into North America and South America, with the North American market divided into the US and Canada.

The European swollen knee treatment market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The swollen knee treatment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The swollen knee treatment market in the Middle East and Africa has been segmented into the Middle East and Africa.

Regional Market Summary

In the swollen knee treatment market, North America is anticipated to account for the largest market share due to the early adoption of advanced medical technologies, the rise in awareness, the rise in growth of the healthcare sector, and due to favorable compensation setting for many surgical procedures.

The European market is expected to hold the second largest market share. The market growth in this region can be attributed to the rising frequency of diabetes patients, increasing number of surgeries, and increasing demand for advanced treatment procedures are boosting the European market.

The market share in Asia-Pacific is also projected to experience growth in the near future due to access to optimal treatment facilities and growing demand for advanced technology, better adoption rate, increase in disposable income, and rising medical tourism.

The market in the Middle East and Africa is expected to account for the smallest share of the global swollen knee treatment market due to an underdeveloped healthcare sector, lack of technical knowledge, and poor medical facilities.

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Research report explores the Kidney Dialysis Equipment Market for the forecast period, 2020-2027

Every day, a healthy individual’s kidneys filter around 120 to 150 quarts of blood. If a person’s kidneys are not working efficiently, the waste gets accumulated in the blood. This may lead to coma and later death. Dialysis avoids the formation of waste products and toxins in the blood.

Dialysis machines are artificial kidneys used to filter patients’ blood during kidney damage, kidney dysfunction, kidney failure, and to remove excess impurities from kidneys. Dialysis machines use hemodialysis to purify the blood and balance the constituents. In this course, the patient’s blood is distributed through the machine which is filtered and well-adjusted for pH electrolytes and fluid concentration before sending it back to the patient’s body. Dialysis machines have extensive applications such as directing medical help to patients suffering from renal diseases.

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Over the last decade, there had been many advances in renal dialysis equipment (both in portable and home dialysis machines), accessories, and consumables. According to the MRFR Research report, the global kidney dialysis equipment market size is likely to grow at a CAGR of 5.7% from an assessed USD 16.5 billion in 2017.

The development in this market is due to the rise in a number of End Stage Renal Disease Patients (ESRD), advanced technologies, and rise in cost-effective and accurate portable dialysis apparatus. The fast growth in the aging population, growing frequencies of diabetes and hypertension problems, and patients opting for dialysis treatments over kidney transplants due to lack of donors boost the market. Additionally, restrains for the market comprise the time consumption, risks and difficulties involved, and rules and regulations associated with dialysis.

Segmentation

The global kidney dialysis equipment market has been segmented on the basis of type, apparatus type, and end-user.

On the basis of type, the market has been classified as hemodialysis, peritoneal dialysis, and Continuous Renal Replacement Therapy (CRRT). Hemodialysis is segmented into conventional hemodialysis, short daily hemodialysis, and nocturnal hemodialysis. The peritoneal dialysis is segmented into Continuous Ambulatory Peritoneal Dialysis (CAPD), Continuous Cycling Peritoneal Dialysis (CCPD), Intermittent Peritoneal Dialysis (IPD), and Tidal Peritoneal Dialysis (TPD).

On the basis of apparatus type, the market has been classified into hemodialysis equipment, peritoneal dialysis equipment, and consumables and continuous renal replacement therapy systems. The hemodialysis equipment segment is categorized into hemodialysis machines, dialyzers and filters, bloodline systems, concentrates and solutions, tunneled hemodialysis catheters, and vascular access devices. The peritoneal dialysis equipment segment is categorized into concentrates and solutions, automated peritoneal dialysis machines, dialyzers, and filters.

On the basis of end-user, the market has been classified into hospitals, clinics, in-center dialysis settings, home care, and ambulatory services.

On the basis of region, the market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas has further been segmented into North America and South America, with the North American market is divided into the US and Canada.

The European kidney dialysis equipment market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The kidney dialysis equipment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The kidney dialysis equipment market in the Middle East and Africa has been segmented into the Middle East and Africa.

Key Players

Some of the key players in the kidney dialysis equipment are Fresenius Medical Care AG & Co. Ka, Davita Healthcare Partners Inc., Baxter International Inc., B. Braun Melsungen AG, Diaverum Deutschland GmbH, Nipro Corporation, Nxstage Medical, Inc., Nikkiso Co., Ltd., Mar Cor Purification, Inc. (A Cantel Medical Company), Asahi Kasei Medical Co., Ltd. (A Subsidiary of Asahi Kasei Corporation). Terumo Corporation, Rockwell Medical, Teleflex Incorporated, and Hemoclean CO., LTD.

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