Transdermal Drug Delivery Systems Market – Qualitative Insights by 2027

 The global transdermal drug delivery systems market is expected to register a healthy CAGR over the forecast period. The market held a market value of USD 5,400.2 million in 2017 and is projected to grow at a CAGR of 4.6% during the forecast period from 2018 to 2023. Transdermal drug delivery system (TDDS) delivers drugs through the skin to systemic circulation at a predetermined rate and maintain the effective concentrations clinically over an extended period. TDDS also called as patches are dosage forms that deliver a therapeutically effective amount of drug via the patients’ skin. Worldwide growing geriatric population along with rising in the prevalence of chronic diseases is the leading factor driving the market growth. In addition, rapid technological advancements in transdermal drug delivery systems and increasing adoption of third-generation delivery systems are expected to augment the market growth during the forecast period. The geriatric population is more prone to develop Q fever. The elderly population across the world is on the surge. The World Health Organization (WHO) reported that the worldwide population aged 60 years and above was 962.0 million in 2017, which is projected to increase to over 2.0 billion by 2050 and further would reach to 3.1 billion by 2100.

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However, disadvantages of delivery systems including edema and irritation, natural limits of drug entry imposed by the skin’s impermeability, and lack of adhesion of the transdermal system to different skin types are anticipated to hinder the market growth over the forecast period. Additionally, drugs that require high blood levels cannot be administered through TDDS as it is limited only to potent molecules, those requiring a daily dose of 10 mg or less, thereby affecting the market growth.

Transdermal Drug Delivery Systems Market Segmentation

The global transdermal (percutaneous) drug delivery systems market has been segmented into product, technology, application, and region.

By product, the market has been segmented into transdermal patches and transdermal semisolids. The transdermal patches segment is further categorized into drug-in-adhesive patches, matrix patches, reservoir membrane patches, and microneedle patches. The transdermal semisolids segment is additionally divided into gels, ointments, and sprays. The transdermal patches segment spearheaded the market in 2017 due to its benefits offered such as improved bioavailability, reduced dosing frequency, lower adverse events, enhanced patient compliance (non-invasive nature), painless application, and drug input termination at any point by the removal of the patch.

On the basis of technology, the market has been divided into electric current, iontophoresis, electroporation, ultrasound, microporation, thermal, and others.

Based on application, the market has been categorized into pain management, cardiovascular diseases, hormone replacement therapy, central nervous system disorders, smoking cessation, contraception, and others.

The global transdermal (percutaneous) drug delivery systems market has been segmented by region into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The transdermal (percutaneous) drug delivery systems market in the Americas has further been segmented into North America and Latin America, with the North American market divided into the US and Canada.

The European transdermal (percutaneous) drug delivery systems market has been segmented into Western Europe and Eastern Europe. The Western Europe transdermal (percutaneous) drug delivery systems market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The transdermal (percutaneous) drug delivery systems market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The transdermal (percutaneous) drug delivery systems market in the Middle East & Africa has been segmented into the Middle East and Africa.

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New research report offers detailed research on developments in Vitamin K2 Market 2027

 The global vitamin K2 market is estimated to touch a valuation of USD 228.27 million by 2023, as per the latest findings of Market Research Future (MRFR). It is predicted to register 31.08%% CAGR over the forecast period (2018-2025). It was previously valued at USD 45 million in 2017. It is primarily driven by the rise in vitamin deficiency cases. An increase in health consciousness coupled with the inclination of consumers towards nutritional supplements can drive the vitamin K2 market growth.

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Rising cases of osteoporosis which can accelerate the aging of tissues is another factor that can positively impact the market. But strict regulations by government federal agencies for approval of supplements can act as a growth deterrent.

Competitive Landscape

Key players in the global vitamin K2 market report include Kappa Bioscience (Norway), NattoPharma (Norway), Gnosis SpA (Italy), Viridis BioPharma (India), Seebio Biotech (China), DSM (The Netherlands), Danisco A/S (U.S.), Geneferm Biotechnology Co. Ltd. (Taiwan), Frutarom (Israel), and Kyowa Hakko Bio Co. Ltd. (Japan).

Segmentation Overview

The global vitamin K2 market is segmented on the basis of product type, source, form, and application.
By product type, the market is segmented into MK-4, MK-7, and others. ‘Others’ include MK-5, MK-8, MK-9, and MK-10. Two major sources discussed include natural and synthetic.
By form, the market is bifurcated into oil and powder. Major applications include nutraceutical & food and pharmaceutical.
For the scope of the report, the global vitamin K2 market is segmented in the following manner

Product Type

• MK-7
• MK-4
• Others

Source

• Natural
• Synthetic

Form

• Oil
• Powder
• Others

Application

• Nutraceutical & Food
• Pharmaceutical

Regional Overview

Based on regions, the global vitamin K2 market is segmented into the Americas, Europe, Asia Pacific (APAC), and the Middle East & Africa (MEA). The Americas held a major market share in 2017 owing to rocketing healthcare costs, focus on health and wellness by consumers, and adoption of herbal medicines. On the other hand, the European region can register a stupendous growth rate thanks to demand for vitamin supplements in Germany, France, and the U.K

Research Methodology

At Market Research Future, we consider the proper blend of accurate, reliable, and relevant data as of prime importance. Our data analysts are adept in exactly interpreting data and gaining appropriate information. The primary research includes a head-to-head interview with eminent market insiders who have a pulse on market trends. The secondary method amplifies pertinent factors of the market that can positively influence the market during the forecast period. Other credible sources such as annual reports, publications by relevant associations, and SEC filings do play an integral part in the planning of the report. To maintain an objective analysis, we have included several proprietary standards for the estimation and validation of market data. Top-down and bottom-up approaches are a part of this analysis for a holistic understanding of the market, and the endeavor is to provide our clients with an edge that would help them gain insights.

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Hyperpigmentation Disorders Treatment Market Growth, Trends and Value Chain 2020-2027

 Market Scenario

The global hyperpigmentation disorders treatment market is accounted for USD 3,915 million in 2017 and expected to register 7.1% CAGR during the forecast period (2018–2023).

Hyperpigmentation disorder refers to harmless skin condition that causes darkened skin patches light brown to black in color. It is a common disorder of the skin and melasma is a common cause of facial hyperpigmentation. There are various types of hyperpigmentation, however, few of the most common such as melasma, solar lentigines, and post-inflammatory hyperpigmentation.

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The increasing demands for outpatient and minimally invasive

dermabrasion procedures, include augmented adoption of lasers in pigmentation disorders treatment and growing expenditure on the cosmetics across the world are expected to drive the growth of the market. Moreover, rising R&D spending and aggressive strategies adopted by the top players such as new product launches are contributing to the growth of the market. According to the American Society of Plastic Surgeons, the number of dermabrasion cosmetic procedures have increased from 42,218 in 2000 to 88,182 in 2016 with a 109% increase during the estimated period.

The lack of adequate reimbursement policy and high costs involved in the establishment of these centers may hamper the growth of the market during the assessment period.

Key Players

Some of the key players in the global hyperpigmentation disorders treatment market Allergan, Inc., Bayer AG, EpiPharm AG, Episciences, Inc., Galderma laboratories (Nestle Skin Health S.A), Obagi Cosmeceuticals LLC, Pierre Fabre, RXi Pharmaceuticals Corporation, SkinCeuticals International, and Vivier Pharma.

Intended Audience

• Medical devices manufacturers
• Pharmaceutical Companies
• Medical devices product distributors and suppliers
• Healthcare providers
• Research institutes and academic centers
• Government associations
• Market research and consulting

Market Segmentation

The global hyperpigmentation disorders treatment market has been segmented on the basis of treatment type, disease indication, end-user, and region.

On the basis of treatment type, the market has been classified as topical drugs, chemical peels, microdermabrasion, laser therapy, phototherapy, and others. the market, by disease indication, has been segmented into melasma, solar lentigines, post-inflammatory hyperpigmentation, and others. based on end-user, the market has been segmented into hospitals, aesthetic clinics & dermatology centers, and others. The topical drugs segment is expected to hold the largest market share of the hyperpigmentation disorders treatment market, by treatment type, during the forecast period. Also, by disease indication melasma segment register the considerable growth in comparison to other disease indication.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The hyperpigmentation disorders treatment market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European hyperpigmentation disorders treatment market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The hyperpigmentation disorders treatment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The hyperpigmentation disorders treatment market in the Middle East & Africa has been segmented into the Middle East and Africa.

Regional Market Summary

The Americas market is expected to be the second-largest hyperpigmentation disorders treatment market. The market growth in this region can be attributed to government funding and support of the healthcare sector coupled with increasing research and development. Moreover, favorable reimbursement policies in American countries are contributing to the growth of the market in this region.

Europe is expected to be the third largest hyperpigmentation disorders treatment market during the forecast period owing to the rising in aging population. Moreover, the government of these countries are more focus to provide best treatment option to their citizen. According to the report published by world health organization, Europe aging population will increase from 14 million in 2016 to 19 million in 2020 and 40 million to 2050.

The market in the Middle East & Africa is expected to account for the smallest share of the global hyperpigmentation disorders treatment market due to an underdeveloped healthcare sector, lack of technical knowledge, and poor medical facilities.

The Asia-Pacific are likely to dominate the global hyperpigmentation disorders treatment market owing to the rising awareness of hyperpigmentation disorders, presence of rapidly developing healthcare technology, huge patient population, and high healthcare expenditure. Moreover, Asia-Pacific is also expected to be the fastest-growing Hyperpigmentation Disorders Treatment market during the forecast period. According to the world bank group, in 2014, China spent 4.96% of gross domestic product (GDP) in healthcare expenditure, whereas in 2015, healthcare expenditure holds 5.32% of GDP. Also, in 2014, India spent 3.63% of GDP on healthcare, however, in 2015 healthcare expenditure holds 3.89% of GDP.

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Global Diabetes Pen Market Industry Production and Demand, Competition News and Trends Forecasts to 2027

 Insulin is a hormone produced by the pancreas.  A diabetes pen is used to inject insulin for the treatment of diabetes. It is composed of an insulin cartridge (integrated or bought separately) and a dial to measure the dose, and is used with disposable pen needles to deliver the dose. Diabetes is a major chronic disease across the globe. Changing lifestyle, high intake of carbohydrates and sugar, and obesity are major factors elevating the prevalence of the disease. Increasing prevalence of diabetes and obesity and growing demand for diabetes pen drive the market for diabetes pen.

The global diabetes pen market size is expected to grow at a CAGR of approximately 8.45% during the forecast period 2017-2023.

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Global Diabetes Pen Market Players
Key players in diabetes pen market: AstraZeneca (U.K), Teruma Medical Corporation (Japan), Greinier Bio One International GmBH (U.S.), F. Hoffman La Roche AG (Switzerland), Becton, Dickinson and Company (U.S.), Bayer Cropscience Ltd. (Germany), and HTL STREFA SA (Poland)

Regional Analysis

Globally, diabetes pen market consists of four regions: North America, Europe, Asia Pacific. and Middle East & Africa. North America is expected to be the largest market for diabetes pen. Reimbursement for diabetes management and technological advancement in production of diabetes pens to administer accurate and safe dose drive this market.  Extensive research and development to enhance the quality of diabetes pens as well as to increase their reliability is also another reason for the growth of this market in North America. Large number of diabetes pen users have been found in European countries, especially in the U.K. leading to an increase in their demand.  Asia Pacific is expected to be fastest growing market for diabetes pen with India being the largest market due to growing expenditure in the healthcare to curb lifestyle disease and improved healthcare infrastructure. The Middle East & Africa, major drivers for rise in this market are initiative to control the elevated levels of diabetes and awareness regarding lifestyle diseases.

Segmentation:

The global diabetes pen market is segmented on the basis of product, which includes insulin pens and insulin pen needle. On the basis of usage, the market is segmented into includes reusable pens and disposable pens used of diabetes pen. And on the basis of distribution channel, the market is segmented into hospital pharmacy, retail pharmacy, online sales, and diabetes clinics.

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Tularemia Market : Dynamics, Segments, Size and Demand, 2020–2027

 Market scenario

Tularemia or rabbit fever or deer fly fever is a rare infectious disease caused by the bacterium Francisella tularensis, which affects skin, eyes, lymph nodes and lungs. Tularemia is transmitted from animals such as rodents, rabbits, and hares to human. It can also affect sheep, birds, dogs, cats, etc. The routes of acquiring infection are direct exposure to the bacteria, airborne infections, insect bites, and bite of an infected animal. Tularemia is highly contagious and had been used as a biological weapon by many countries such as United States of America and Soviet Union. Ulceroglandular tularemia is the most common form of Tularemia. Tularemia symptoms include swollen and painful lymph glands, fever, chills, headache, fatigue, eye swelling, pain and light sensitivity, diarrhea, pneumonia etc. If it left untreated, it will cause serious complications such as enlarged spleen, enlarged liver,    infection around the brain and spinal cord, irritation around the heart (pericarditis), bone infection etc. and may lead to the death.

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Factors favouring the spread of Tularemia infection are tick bites, exposure to sick or dead animals, especially, wild game. Travel to certain regions such as Arkansas, Missouri and Oklahoma can also cause Tularemia infection because of the concentration of ticks in those areas. Tick bite is the leading cause for an occurrence of large number of cases.Laboratory workers working with tularemia are at risk of airborne infection due to greater chances of exposure to the pathogen. Tularemia infection can also be airborne during gardening, construction or other activities, which may lead to pneumonic tularemia. Tularemia is also contracted by eating undercooked meat of an infected animal or drinking contaminated water. According to Centers for Disease Control and Prevention, overall mortality of Tularemia is less than 2% but ranges up to 24% depending on the strain.

The global Tularemia market size is expected to reach US$ 200 million by 2023, and the market is projected to grow at a CAGR of ~ 3.2 % during the forecast period 2017-2023.

Segments

The global Tularemia market has been segmented on the basis of types, diagnosis, drugs, and end users.

Based on types, the market has been segmented as the ulceroglandular tularemia, glandular tularemia, oculoglandular tularemia, oropharyngeal tularemia, pneumonic tularemia, and others.

Based on the diagnosis, the market has been segmented as microscopy, immunochemistry, and others.

Based on the drugs, the market has been segmented as streptomycin, gentamicin, doxycycline, ciprofloxacin and others.

Based on the end users, the market has been segmented as hospitals and clinics, academic and research centers, and others.

Regional analysis

The Americas accounts for the significant market share owing to extensive use of medications and high expenditure on the health care. Additionally, the fastest uptake of new technology and drugs in the US drives the global Tularemia market. However the presence and concentration of Tularemia in the US regions, for instance, Arkansas, Missouri, Dakota, Oklahoma, etc. are the leading cause for the dominance of US in the global Tularemia market. Europe is the second largest market in the globe due to a high disposable income and rising awareness about the disease.

Asia Pacific region is expected to grow rapidly and China and India are likely to lead the market due to unmet needs during the forecast period.

Gulf nations such as Saudi Arabia and the UAE drive the Middle East & African market. The African region is expected to witness a moderate growth owing to poor economic and political conditions and poor healthcare development. However Africa is also a region of high endemic and untreated cases of Tularemia.

Key Players in the Global Tularemia Market

Some of key players profiled in the report are Nicholas Piramal, Alkem, Glaxo Smithkline, Bayer AG, Ranbaxy Laboratories, Cipla Inc., Zydus Cadila, Dr. Reddy's Lab, Glenmark Pharmaceuticals, Lupin Limited, pfizer Inc. and others.

The report for Global Tularemia market by Market Research Future comprises of extensive primary research along with the detailed analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of the current market scenario which includes past and estimated future market size with respect to value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information about and strategies used by top key players in the industry. The report also gives a broad study of the different market segments and regions.

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Flexible Spinal Implants Market – Qualitative Insights by 2027

 Technological advancements in spine implants, increasing aging and obese population, rising cases of spine deformities, demand for minimally invasive spine surgery, growth in the number of hospitals offering spinal surgeries are fueling the growth of global flexible spinal implants market. The market restraints are stringent product approval process, uncertain reimbursement scenario, high cost of treatment procedures, concerns about safety of advanced products etc.

Considering all these factors the flexible spinal implants mareket size is expected to reach 4 billion USD by the end of 2023, this market is projected to growing at a CAGR of ~ 13.2 % during 2017-2023.

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Key Players of Global Flexible Spinal Implants Market:

Key players profiled in the report are Paradigm Spine LLC, Medtronic plc., Abbott Spine, Inc.,  Raymedica, K2M Group Holdings, Stryker Corporation, Zimmer Biomet Holdings, Inc., B. Braun Melsungen AG, Alphatec Holdings, Inc., NuVasive, Inc., Orthofix International N.V., and others.
Intended Audience

• Global flexible spinal implants solution providers, manufacturers & suppliers
• Research and development (R&D) companies
• Market research and consulting service providers
• Academic institutes and universities

Market Segments:

The global flexible spinal implants market is segmented on the basis of type and applications. Based on type, the market has been segmented as rods, hooks, pedicle screws, plates, cages and other. Based on the applications, the market has been segmented as thoracic, lumbar, cervical, artificial discs and other.

Study objectives:

• To provide a detailed analysis of the market structure along with estimated future growth forecast for the next 6 years about various segments and sub-segments of the global flexible spinal implants market.
• To provide insights about factors affecting the market growth.
• To analyze the global flexible spinal implants market based on various factors – price analysis, supply chain analysis, Porters Five Force analysis etc.
• To provide past and estimated future revenue of the market’s segments and sub-segments with respect to four main geographies and their countries – Americas, Europe, Asia Pacific along with Middle East & Africa.
• To provide country level analysis of the market with respect to the current market size and future growth prospects.
• To provide country level analysis of the market’s segments which includes by type and applications.
• To provide overview of key players and their strategic profiling in the market, comprehensively analyzing their core competencies, and drawing a competitive landscape of the market.
• To track and analyze developments which are competitive in nature such as joint ventures, strategic alliances, mergers and acquisitions, new disease developments along with research and developments that are currently taking place in the global flexible spinal implants markets.

Regional Aanalysis:

US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness. Asia Pacific region is the fastest region because of large unmet needs which is led by China and India. The Middle East and Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The poor regions of Africa are expected to be a laggard due to poor economic and political conditions.

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Muscle Stimulator Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

 The muscle stimulators use electric current to elicit contraction in muscles or nerves. The electric signal has intensity and frequency which mimics the nerve signal system. The market for muscle stimulator is rising due to drivers such as increasing popularity of sports and increased demand for fitness products, increasing healthcare expenditure and rising affordability of muscle stimulators, demand for non-invasive technology devices and growing preference for muscle stimulators among physiotherapists etc. The rising population of geriatrics is also a strong stimulant. According to the world health organization by 2050, the world’s population aged 60 years and older is expected to total 2 billion, up from 900 million in 2015.

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The world health organization also estimates that today, 125 million people are aged 80 years or older. Thus the huge rise in geriatrics around the globe, will drive the market due to greater frequency of muscle ailments in the geriatrics population. There has been increasing incidence of muscle diseases and disorders such as low back pain, spinal injuries etc. are driving the market. The rise of risk factors such as growing prevalence of diabetes, increasing incidence of accident injuries, occupational injuries etc. is driving the growth of these diseases.

The restraints include competition from alternative therapies such as acupuncture, yoga, and aroma therapy etc., lack of usage guidelines and safety concerns and regulatory uncertainties in the US.

Considering all these factors the muscle stimulator market size is expected to reach $ 768.3 million by the end of 2023, this market is projected to growing at a CAGR of ~ 6.1 % during 2017-2023.
Study objectives:

• To provide detail analysis of the market structure along with estimated future growth forecast for the next 6 years about various segments and sub-segments of the global muscle stimulator market.
• To provide insights about factors affecting the market growth.
• To analyze the global muscle stimulator market based on various factors – price analysis, supply chain analysis, Porters Five Force Analysis etc.
• To provide past and estimated future revenue of the market’s segments and sub-segments with respect to four main geographies and their countries – Americas, Europe, Asia-Pacific along with Middle East & Africa.
• To provide country level analysis of the market with respect to the current market size and future growth prospect.
• To provide country level analysis of the market’s segments which includes by products, and by application.
• To provide overview of key players and their strategic profiling in the market, comprehensively analyzing their core competencies and drawing a competitive landscape of the market.
• To track and analyze developments which are competitive in nature such as joint ventures, strategic alliances, mergers and acquisitions, new disease developments along with research and developments currently taking place in the global muscle stimulator market.

Key players of Global Muscle stimulator Market:

Key players profiled in the report are DJO Global, Inc., Mettler Electronics Corp., Axiobionics, Zynex, NeuroMetrix, Inc., OMRON Corporation, Tone-A-Matic and others.

Segments:

The global muscle stimulator market is segmented on the basis of products. Based on the products, the market has been segmented as transcutaneous electrical nerve stimulator, burst mode alternating current, neuromuscular electric stimulation, and interferential current. Based on the application, the market has been segmented as pain management, neurological and movement disorder management and musculoskeletal disorder management.

Regional analysis

US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness. Asia pacific region will be the fastest region because of large unmet needs which will be led by China and India. The Middle East and Africa market will be led by the gulf nations particularly Saudi Arabia and UAE. The poor regions of Africa is expected to be a laggard due to poor economic and political conditions.

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