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Wednesday, 26 May 2021

New research report offers detailed research on developments in Biopharmaceuticals Market 2027

Biopharmaceuticals Market Synopsis

Biopharmaceuticals are medical drugs produced using biotechnology. Biopharmaceuticals can be proteins (including antibodies), nucleic acids (DNA, RNA, or antisense oligonucleotides) that are used for therapeutic or in vivo diagnostic purposes. These are produced by various means, including direct extraction from a native (non-engineered) biological source. The first such biopharmaceutical approved for therapeutic use was recombinant human insulin (RHI, trade name Humulin), which was developed by Genentech and marketed by Eli Lilly and Company in 1982. Growing market demand for biopharmaceuticals, rising investment by major companies on research & development of biopharmaceuticals, the high incidence rate of chronic diseases, and increasing acceptance for biopharmaceuticals due to their ability to treat previously untreatable diseases is expected to drive the market growth. As of September 2019, approximately six in 10 adults in the US suffer from a chronic disease. Moreover, rising geriatric population and increasing technological advancements are also anticipated to fuel the market growth.

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Biopharmaceuticals Market is expected to hold a value of USD 471,021.1 Mn by 2027 at a CAGR of 9.13%.

The global biopharmaceuticals market is growing owing to various factors such as increasing investment by major companies on research & development of biopharmaceuticals and increasing acceptance for biopharmaceuticals due to their ability to treat the previously untreatable diseases. Furthermore, the number of geriatric populations is, tremendously, the incidence rate of chronic diseases is also high, and technological advancements are growing which are also expected to fuel the market growth. However, the entry of low-cost biosimilars, risk of side effects that can occur due to high usage of biopharmaceuticals, and stringent government regulations are expected to pose as restraints to the growth of the global biopharmaceuticals market.

Several market players currently dominate the global biopharmaceuticals market. The key players are involved in product launches and acquisitions to strengthen their market positions.

Segmentation

The global biopharmaceuticals market has been segmented based on product type and application.

The global biopharmaceuticals market has been segmented, on the basis of product type, into monoclonal antibodies, recombinant growth factors, purified proteins, recombinant proteins, recombinant hormones, vaccines, synthetic immunomodulators, and others. The recombinant growth factors has been further bifurcated into erythropoietin and granulocyte colony-stimulating factor. The purified proteins segment has been further classified as leukemia inhibitory factor (LIF), P53 protein, P38 protein, and others. The recombinant proteins segment has been further divided into serum albumin, amyloid protein, defensin, transferrin, and others. Vaccines have also been segregated into recombinant vaccines, conventional vaccines, and others. The recombinant vaccines have been further sub-segmented into cancer vaccines, malaria vaccines, Ebola vaccines, hepatitis B vaccines, tetanus vaccines, diphtheria vaccines, cholera vaccines, and others. Conventional vaccines have been categorized as polio vaccines, pox vaccines, and others. Synthetic immunomodulators segment has been further divided into cytokines, interferons, interleukins, tumor necrosis factor (TNF), and others. Monoclonal antibodies segment is anticipated to hold the largest market share in the global biopharmaceutical market due to the increasing number of research activities that are supported by the usage of monoclonal antibodies. Vaccines are expected to grow at the fastest CAGR owing to the rising awareness of chronic diseases.

The market based on application has been segmented into oncology, inflammatory & infectious diseases, autoimmune disorders, metabolic disorders, hormonal disorders, disease prevention, cardiovascular diseases, neurological diseases, and others. The oncology segment is expected to hold the largest share of the market due to the high prevalence of cancer. In 2019, 606,880 cancer-related deaths occurred in the US. The neurological diseases segment is expected to grow at the fastest CAGR owing to the rising prevalence of neurological disorders such as Parkinson’s disease and epilepsy. Nearly 60,000 people in America are diagnosed with Parkinson’s disease every year.

Key Players

Some of the key players in the Global Biopharmaceuticals Market are Pfizer Inc. (US), Amgen Inc. (US), Eli Lilly and Company (US), F. Hoffmann-La Roche Ltd (Switzerland), Johnson & Johnson (US), Gilead Sciences, Inc. (US), AstraZeneca (UK), Abbvie Inc. (US), Sanofi (France), Bristol-Myers Squibb Company (US), Sandoz International GmbH (Germany), Novo Nordisk A/S (Denmark), GlaxoSmithKline PLC (UK), Merck KGaA (Germany), and Biocon (India).

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Gene Therapy Market Growth, Trends and Value Chain 2020-2027

According to MRFR analysis, the global gene therapy market is expected to register a CAGR of 40.7% during the forecast period of 2019 to 2025 and was valued at USD 524 million in 2018.

Gene therapy is a technique in which a piece of DNA is incorporated into the cell via a vector. The key players are investing in the manufacturing of cell and gene therapy treatments due to its target specificity. The gene therapy is mainly of two types, somatic gene therapy, and germline gene therapy, depending on the type of cells its targets.

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The growth of the global gene therapy market is attributed to various factors such as robust product pipeline, increasing investment by key players, and high prevalence of target diseases and demand for innovative medication. However, the high cost of product development and stringent regulatory policies are expected to curb the growth of the global gene therapy market. The global gene therapy market is currently dominated by several market players. The key players are involved in product launches and strategic collaborations to strengthen their market positions.

Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is expected to be the largest market owing to the increasing prevalence of gene therapy and rising per capita healthcare expenditure. The gene therapy market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The European gene therapy market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The gene therapy market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing number of patients and raising awareness about the treatment methods, the market in Asia-Pacific is expected to be the fastest-growing. The gene therapy market in the Middle East & Africa has been divided into the Middle East and Africa.

Segmentation

The global gene therapy market has been segmented based on product, indication, and end user.

The market, based on product, has been divided into kymriah, luxturna, yescarta, zolgensma, strimvelis, zynteglo, imlygic, and others.

The global gene therapy market has on the basis of indication is segmented, into oncology, genetic diseases/ disorders, and others. The oncology segment is expected to hold the largest market share and to be the fastest-growing segment due to high prevalence of cancer and robust pipeline for cancer gene therapy.

The end-user segments of the market are hospitals & clinics, specialty treatment centers, and others. The hospitals & clinics segment is expected to hold the largest market share due to increasing number of hospitals. Also, hospitals are generally the first treatment choice for diseases.

Key Players

Some of the key players in the global gene therapy market are Amgen, Inc. (US), Novartis AG (Switzerland), Spark Therapeutics, Inc. (US), Gilead Sciences, Inc. (US), uniQure N.V. (Netherlands), Orchard Therapeutics plc (UK), Celgene Corporation (US), Bristol-Myers Squibb Company (US), Thermo Fisher Scientific Inc. (US), CEVEC (Germany), and Lonza (Switzerland).

Hearing Aids Market to Witness Widespread Expansion During 2020-2027

Market Forecast

Hearing Aids Market is expected to cross USD 10.2 Billion by 2025 at a CAGR of 7%.

Market Synopsis

The technological advancements and launch of new products are expected to fuel the global hearing aids market.

Market Influencer

Technological advancements for the development of products by hearing aids manufacturers which along with improved hearing experience also have sleek appearance promoting the use of hearing aids.

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The growth of global hearing aids market is driven by various factors such as increasing incidence of hearing loss, the launch of new products, increasing geriatric population, and raising awareness about hearing loss treatment. However, the low penetration of hearing aids and product recalls are expected to curb the growth of the global hearing aids market.

The global hearing aids market is currently dominated by several market players. The key players are involved in product launches and strategic collaborations to strengthen their market positions.

Regional Analysis

The market has been divided, by region, into Europe, the Americas, Asia-Pacific, and the Middle East & Africa. Europe is expected to be the largest market owing to the rising incidence of hearing loss and sophisticated healthcare infrastructure. The European hearing aids market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The Americas holds the second largest market share. The hearing aids market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The hearing aids market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing awareness regarding the use of hearing aids and increasing population affected by hearing disorders, the market in Asia-Pacific is expected to be the fastest-growing. The hearing aids market in the Middle East & Africa has been divided into the Middle East and Africa and is expected to hold the least market share.

Segmentation

The global hearing aids market has been segmented based on product, product type, type of hearing loss, technology type, and distribution channel.

The market, based on product, has been divided into devices, implants, and accessories, out of which implants is the fastest-growing segment. For instance, the Australia-based manufacturer Cochlear Ltd reported a profit of USD 265 to USD 275 million in first quarter of 2019, 8% to 12% more as compared to that in the first quarter of 2018.

The global hearing aids market has been segmented, on the basis of product type, into wired and wireless. Wireless is the fastest-growing segment owing to technological advancements and product launches. For instance, Sonova, in November 2018 launched products based on SWORD (Sonova Wireless One Radio Digital) chip. The new technology allows hearing instruments to connect with electronic devices such as televisions or mobile phones.

The type of hearing loss segments of the market are sensorineural, conductive, and others. The growth of the segment is due to the high prevalence of hearing loss. For instance, in 2018, around 2 to 3 out of 1000, children in the US are born with a hearing loss in one or both ears.

The technology type segment of the market is segmented as digital hearing aids and analog hearing aids. The digital hearing aids segment is expected to be both, the largest shareholder and the fastest-growing segment owing to its advantages over analog counterparts.

The distribution channel segment is classified into retail stores, E-commerce, and others. The E-commerce segment is expected to be the fastest-growing segment owing to ease of access to products for customers.

Key Players

Some of the key players in the global hearing aids market are Sonova (Switzerland), Cochlear Ltd. (Australia), GN Store Nord A/S (Denmark), Sivantos Pte. Ltd. (Singapore), Arphi Electronics Private Limited (India), Demant A/S (Denmark), Starkey (US), WIDEX INDIA PRIVATE LIMITED (Denmark), Zounds Hearing (US), SeboTek Hearing Systems, LLC (US), Audina Hearing Instruments, Inc. (US), and Microson (Spain).

Proteomics Market Analysis and Value Forecast Snapshot by End-use Industry 2020-2027

Market Scenario:

Global Proteomics Market is expected to grow significantly over the forecast period. It is anticipated that the market held a valuation of USD 23.2 Billion in 2017 and is projected to grow at a CAGR of 14.1% over the forecast period. Proteomes are a set of proteins which are produced in a system, organism, or any biological entity. Study of proteomes is known as proteomics. It is used in various applications, like investigation of protein expression, transcriptional & post transcriptional studies, metabolic pathways, protein interaction in diseases, etc.

The factors such as increasing research & development activities in the healthcare industry, rising demand for personalized medicines, rising number of approvals of personalized medicines and increasing activities of drug discovery are expected to propel the growth of the market. According to Foley & Lardner LLP, Food and Drug Administration (FDA) approved 16 new personalized medicine therapies in 2017. However, the high cost of devices and lack of skilled researchers can hamper the market growth over the forecast period.

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Segmentation:

The Global Proteomics Market has been segmented into equipment, service and applicationThe market, on the basis of equipment, has been segmented into chromatography, mass spectroscopy, protein microarray, x-ray crystallography, protein fractionation and others.The market, by services, has been segmented into laboratory services and data analysis & services. The laboratory services segment accounted for the largest market share owing to its benefits in effective diagnosis and research for drug discovery. Data analysis and services is expected to register the highest CAGR owing to increasing demand for data analytics.The market, by application, has been segmented into drug discovery, clinical diagnosis and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Proteomics Market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada. The European Proteomics Market has been segmented into Western Europe and Eastern Europe. Western Europe has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The Proteomics Market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The Proteomics market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key players:

GENERAL ELECTRIC COMPANY, Bio-Rad Laboratories, Inc., Danaher, Siemens Ltd., Thermo Fisher Scientific Inc. Inc., Agilent Technologies, Inc., Genzyme Corporation, Biognosys AG, Bruker, Luminex Corporation, Merck KGaA, PerkinElmer Inc., WATERS, Caprion Biosciences Inc. and others are some of the key players in the Global Proteomics Market.

Regional Market Summary

Geographically, the Americas is anticipated to dominate the global proteomics market owing to rising funding from government, rising awareness regarding applications of proteomics, cost effectiveness and increasing demand for personalized medicines. According to a report published in a journal named Leukemia Research in November 2017, personalized medicines improve life of cancer patients by 7 months at USD 32,000.

Europe is expected to hold the second largest position in the Global Proteomics Market. The market growth in this region is attributed to rising cancer research activities and government support. The proteomics market in Asia-Pacific region consists of countries namely China, Japan, Republic of Korea, India, Australia and the Rest of the Asia-Pacific. The Asia-Pacific region is expected to be fastest growing region owing to the increasing demand for personalized medicine due to rising prevalence of cancer and other such diseases and presence of large number of manufacturers of personalized medicines in the region. According to a report published by the National Institute of Cancer Prevention and Research (NICPR), around 2.25 million people in India are living with cancer in 2018.

The Middle East & Africa are expected to hold the least share of the market. The market growth in this region is expected to be driven by a developing healthcare infrastructure.

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Viral Vector Manufacturing Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

Market Scenario:

Global viral vector manufacturing market is expected to grow significantly over the forecast period. It is projected that the global viral vector manufacturing market is expected to register a CAGR Approx. 22.65% with an expected market value of USD 319 million during the forecast period of 2018–2023. Gene therapy is one of the preferred treatment options for most chronic diseases, involving insertion of a functional copy of a gene into a defective cell. Viral vector methods are used in effective transfer of therapeutic gene into the target cells. Viral vectors used in gene therapy include retroviral vectors, adenoviral vectors and adeno-associated viral vectors.

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Numerous factors such as rise in number of clinical trials, increase in the number of gene therapy candidates, and growing necessity for an effective mode of disease treatment are expected to drive the growth of the market. Also, the characteristics of viral vectors such as ability to express therapeutic genes efficiently, and non-pathogenic nature fuels the growth of the market. Moreover, several companies involved in the development of viral agent-based products often seek support in terms of strategic collaborations and acquisitions with contract service providers to deliver a clinical grade product. This is mainly because of the limited availability and complexity of platform and technologies used for vector designing, production, packaging, and release testing. For example, in December 2017, Merck announced a commercial supply agreement to manufacture viral vectors for Bluebird Bio, Inc. for its use in potentially transformative gene therapies. This move will accentuate the life science business of Merck as a leading contract manufacturing organization and commercial provider of viral vectors for gene therapy.

However, high cost of gene therapies and possible mutagenesis may hamper the market growth during the assessment period.

Segmentation:

The global viral vector manufacturing market has been segmented into type, disease, application, and end-user.

The market, on the basis of type, has been segmented retroviral vectors, adenoviral vectors, adeno-associated viral vectors, and other viral vectors.

The segment, by retroviral vectors is anticipated to be the largest segment. Retro viruses contain an enzyme reverse transcriptase which allows the integration into the host genome. This has increased the usage of retroviral vectors in various treatment options, whereas the adenoviral vectors segment is estimated to be the fastest growing segment owing to their increased use in the in-vivo and in-vitro experiments.

The market, by retroviral vectors, has been further segmented into lentiviral vectors and gamma-retroviral vectors.

The market, by disease, has been segmented into cancer, genetic disorders, infectious diseases, and others.

The market, by application, has been segmented into gene therapy and vaccinology.

The market, by end-user, has been segmented into pharmaceutical and biotechnology companies, research institutes, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The viral vector manufacturing market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European viral vector manufacturing market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The viral vector manufacturing market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The viral vector manufacturing market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key players:

FUJIFILM Diosynth Biotechnologies U.S.A., Inc., Sanofi, Lonza, Merck KGaA, GENERAL ELECTRIC COMPANY, Oxford BioMedica, Spark Therapeutics, Inc., uniQure N.V., FinVector Vision Therapies, Brammer Bio, Cell and Gene Therapy Catapult, Cobra Biologics, REGENXBIO Inc., and Kaneka Eurogentec S.A. are some of the key players in the global viral vector manufacturing market.

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Cell Harvesting Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

The global cell harvesting market is expected to grow significantly over the forecast period. It is estimated that the global cell harvesting market is expected to register a CAGR of Approx. 8.75% with an estimated market value of USD 209.5 million during the forecast period from 2018 to 2023. Cell harvesting is performed by separating the cell culture from the growing medium, involving techniques such as centrifugation, microfiltration, and depth filtration.

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Numerous factors such as an increase in chronic infections and diseases, the rapid growth of the biotechnology and pharmaceutical industries, and rising research in regenerative medicines are expected to drive the growth of the market. Moreover, the cost-effectiveness, ease of use, the durability of harvesters, technological advancements, and design development of cell harvester devices fuel the growth of the market. Several companies are also involved in new product launches to strengthen their position in the market. For instance, in September 2018, AVITA Medical, a global regenerative medicine company, announced that the US Food and Drug Administration (FDA) approved the Company’s Premarket Approval (PMA) application to market the RECELL Autologous Cell Harvesting Device (RECELL System). This device helps to treat severe burns in patients of 18 years and older.

Key players:

ads-tec GmbH, Argos Technologies, Inc., Arthrex, Inc., Avita Medical, Bertin, connectorate, Cox Scientific, hynoDent AG, PerkinElmer Inc., Scinomix, Teleflex Incorporated, and TERUMO CORPORATION are some of the key players in the global cell harvesting market.

Intended Audience

Pharmaceutical companies
Biotechnology companies
Cell harvester vendors
Research and Development (R&D) companies
Government research institutes
Academic institutes and universities

However, the technical complexity of harvesters, coupled with ethical issues related to embryonic stem cell research may curb the growth of the market. Stringent government regulations and mandatory licensing rules may also hamper the market growth during the assessment period.

Market Segmentation:

The global cell harvesting market has been segmented into product type, application, and end user.

The market, on the basis of product type, has been segmented into manual cell harvesters and automated cell harvesters.

The manual cell harvesters segment is estimated to hold the largest share owing to the high preferability of manual cell harvesters, whereas the automated cell harvesters segment is expected to be the fastest growing segment due to increased awareness and rise in the use of automated technologies in devices.

The market, by application, has been segmented into biopharmaceutical application, stem cell research, and others.

The market, by end user, has been segmented into pharmaceutical companies, biotechnology companies, research institutes, and others.

The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East and Africa.

Regional Market Summary

Geographically, the Americas is anticipated to dominate the global cell harvesting market owing to a well-developed healthcare sector and growing healthcare expenditure. For instance, according to the data published by the Committee for a Responsible Federal Budget in May 2018, the US spent about USD 3.5 trillion, or 18% of its Gross Domestic Product (GDP) on health expenditures, which accounted for more than twice the average among developed countries in 2017. Additionally, many companies in this region focus on the innovation of new treatment options, thus being a lucrative option for the growth of the market in this region.

Europe is expected to hold the second largest position in the global cell harvesting market. The market growth in this region owes to the availability of funds for research. For instance, according to the data published by the National Institute of Health Funding (NIHR) in 2016, funding of EUR 928 million was announced for new NIHR Biomedical Research Centers (BRC) and NIHR Clinical Research Facilities (CRF) for five years starting from April 2017.

Asia-Pacific is anticipated to be the fastest growing region in the market due to the presence of a huge patient population and continuously developing economies.

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Bioburden Testing Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

Global Bioburden Testing Market is expected to grow significantly over the forecast period. It is estimated that the global bioburden testing market is expected to register a CAGR of Approx. 9.15% during the forecast period of 2018–2023 with an estimated market value of USD 455 million. Bioburden testing refers to an estimation of microbial load on a medical instrument, raw material, packaged goods among others. Bioburden testing is carried out to ascertain if the types and numbers of micro-organisms present are satisfactory or unsatisfactory when compared to predefined acceptance criteria.

Several factors such as increasing food safety concerns, rising medical spending, growing product recalls due to microbial contamination are expected to drive the growth of the market. The major players are involved in strategic collaborations and new product launches to strengthen their position in the market. For instance, in October 2018, SGS SA acquired IBR Inc., a non-clinical contract research organization (CRO). IBR Inc. focuses on integral services in biopharmaceutical analytics for the development of biologics, biosimilars and vaccines, and provides several filter testing and particle counting services.

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However, high costs of microbial enumeration instruments and complex and time-consuming regulatory standards in some economies may hinder the market growth during the assessment period. Also, test reports and certificates tend to be different from one country to another which hampers international trade. Therefore, in December 2017, International Organization for Standardization (ISO) published a new edition of ISO/IEC 17025 standard. This standard is an international reference for laboratories carrying out calibration and testing activities around the world. ISO/IEC 17025 helps facilitate cooperation between laboratories and other bodies by generating wider acceptance of results between countries.

Segmentation:

The global bioburden testing market has been segmented into test type, product type, application and end-user.

The market, on the basis of type, has been segmented into aerobic count, anaerobic count, fungi count and spore count.

The market, on the basis of product type, has been segmented into consumables and instruments.

The market, by consumables, has been sub-segmented into reagents and kits, and others.

The market, by instruments, has been further segmented into polymerase chain reaction machine (PCR), microscopes, and others.

The market, by application, has been segmented into raw materials testing, medical devices testing, in-process material testing, sterilization validation testing, and equipment cleaning validation.

The market, by end-user, has been segmented into pharmaceutical and biotechnology companies, microbial testing laboratories, and others.

The market, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The bioburden testing market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.

The European bioburden testing market has been segmented into Western Europe and Eastern Europe. Western Europe has been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The bioburden testing market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The Bioburden Testing market in the Middle East & Africa has been segmented into the Middle East and Africa.

Key players:

Charles River, SGS SA, WuXi AppTec, Merck KGaA, NORTH AMERICAN SCIENCE ASSOCIATES INC., Becton, Dickinson, and Company, Nelson Laboratories, LLC, Pacific Biolabs, ATS Laboratories, Inc., and Dynatec Labs are some of the major players in the global bioburden testing market.

Geographically, the Americas is anticipated to dominate the global bioburden testing market owing to a well-developed healthcare infrastructure, and growing healthcare expenditure. Moreover, favourable reimbursement scenario in this region fuels the growth of the market.

Europe is expected to hold the second largest position in the global bioburden testing market. The market growth in this region is attributed to the availability of funds for research.

Asia-Pacific is anticipated to be the fastest growing region in the market due to the presence of a huge patient population, continuously developing economies, and increasing government funding for healthcare sector. Also, there is a strong presence of major players in this region which boosts the market growth.

On the other hand, the Middle East and Africa has the least share of the market. Majority of the market share of this region is expected to be held by the Middle East region due to the growing government initiatives for the healthcare sector.

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