Protein Assays Market 2020 Global Trend, Segmentation and Opportunities Forecast To 2027

 Protein assays are utilized in life science research to detect the presence of protein in a sample. There are various assays available in the market differing from each other on the basis of sensitivity, principle and methodology. The macro factors such as sample size, amount, interfering agents and reproducibility are also responsible for its quantification. Protein assays rely mostly on color change i.e. colorimetric assay and use of standard protein such as immunoglobulin G (IgG) or bovine serum albumin (BSA). Protein quantification is the most important step before separation and analysis by electrophoresis or chromatography or any other immunochemical techniques.

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The use of protein assays for early diagnosis of diseases such as cancer and HIV may significantly reduce the morbidity and mortality of the disease. These assays are cost effective, facile and reproducible. Commonly used protein assay are Bradford, Lowry, BCA, and UV spectroscopic protein assays. Thus, use of assay in disease diagnosis, drug discovery and development encourages the biotechnology and pharmaceutical industry to invest in R&D, which fuels the demand of protein assays market.

Several new biomarker identification systems are launched by the key players which grants various opportunities for the global protein assay market. For instance, in June 2017, Gyros Protein Technologies AB launched a new version of its anti-drug antibody (ADA) solution for the immunogenicity market. This solution enables customers to automatically run the assays in a time-efficient manner using small volumes of patient samples and reagents, and shorten run-times.

According to a publication by Pharmaceuticals Research and Manufacturers of America (PhRMA), the organizations spent approximately .8 billion on R&D in 2015 accounted for the largest part of all the biopharmaceutical R&D spending in the U.S. However, high cost of multiplex assay hardware is limiting the growth of global protein assay market.

The global upcoming protein assays market trends expected to grow at a CAGR of approximately 10.8% during the forecast period 2017-2023.

Segmentation

The protein assays is segmented on the basis of type, application, product, technology and end-users.

On the basis of type, the market is segmented into copper-ion-based assays, test strip-based assays, dye-binding assays, and others

On the basis of application, market is segmented into diagnosis, drug discovery, protein purification and others

On the basis of product market is segmented into reagents & kits, instruments and others

On the basis of technology, market is segmented into colorimetric-based protein assays, fluorescence-based protein assays, and absorbance-based protein assays

On the basis of end-user, the market is segmented into hospitals & diagnostic centers, academic institutes, pharmaceutical & biotechnology companies and others.

Regional Analysis

The global protein assays market consists of countries namely America, Europe, Asia Pacific, and the Middle East.

North America is projected to hold the largest share of the global protein assay market due to presence of superior research and development base, strong regional economics, and greater emphasis on disease prevention and wellness by governments.

The European protein assay market is expected to witness rapid growth owing to the high investment in various private and government funded research and development programs in the region and increased spending on pharmaceutical and biotechnology industry development.

Countries such as China, Japan, and India in Asia Pacific are also poised to be promising markets for protein assay in the near future. The healthcare expenditure in Asia increased due to an extension of state health care programs and the increasing affluence of the population. India is anticipated to witness an expansion in spending due to a government resolution to enhance healthcare services. Moreover, China and South Korea are striving to develop their biotechnology sector for diagnosis purpose. China’s efforts to develop its biotech sector has shown good results in sectors such as vaccines and biological products and the same can be expected in the protein assays industry. However, low research and development (R&D) yields, high infrastructure cost, stringent regulatory framework, and lack of trained resources are some of the restraints of the protein assay market.

The Middle East region is expected to grow at a faster rate due to the factors such as the extensive development of health care infrastructure and growing emphasis on research and development in the health care sector.

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Cowden Syndrome Market to Witness Widespread Expansion During 2020-2027

 Cowden syndrome is part of the PTEN hamartoma tumor syndrome. Cowden syndrome is characterized by a high risk of both benign and cancerous tumors of the breast, thyroid, endometrium, colorectal, kidney, and skin. The global Cowden syndrome market is expecting a healthy growth in the coming future. The global market is majorly driven by increasing Cowden syndrome patients across the globe. Additionally, increasing smoking population and rising consumption of alcohol have spurred the growth of the market. However, long time for approval and side effects of the treatment may hinder the growth of the market.

The global Cowden syndrome market analysis expected to grow at a CAGR of 6.7% during the forecast period 2017-2023.

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Key Players

Some of key the players in the market are Amgen, Inc. (U.S.), Eli Lilly and Company (U.S.), AstraZeneca Plc. (U.K.), Bristol-Myers Squibb Company (U.S.), Sanofi (France), AbbVie Inc. (U.S.), Spectrum Pharmaceuticals Inc. (U.S.), Novartis AG (Switzerland), GlaxoSmithKline Plc. (U.K.), Bayer AG (Germany), Takeda Pharmaceuticals (Japan), Pfizer, Inc. (U.S.), Merck & Co., Inc. (U.S.), F. Hoffmann-La Roche Ltd. (Switzerland), Janssen Biotech, Inc. (U.S.), Immunomedics (U.S.), and Oncomed Pharmaceuticals (U.S.)

Segmentation

The global Cowden syndrome market is segmented on the basis of site, treatment and end users.

On the basis of the site, the market is segmented into the breast, thyroid, endometrium (uterus), colorectal, kidney, skin (melanoma), and others.

On the basis of the treatment, the market is categorized into genetic testing, chemotherapy, surgery & radiation therapy, targeted therapy, hormone therapy, biologic therapy, and other. The chemotherapy is further segmented into anthracyclines, taxanes, antimetabolites, and alkylating agents. The targeted therapy is sub-segmented with monoclonal antibodies and tyrosine kinase inhibitors. Hormone therapy is further segmented into selective estrogen-receptor modulators (SERMs), aromatase inhibitors, and others.

On the basis of end users, the market is segmented into hospital & clinics, ambulatory care centers, and others.

Regional Analysis

The Americas dominate the global Cowden syndrome market owing to the increasing prevalence of people suffering from Cowden syndrome and cancer. Additionally, high healthcare expenditure, well-developed technology, and strong government support for research & development have fuelled the growth of the Americas Cowden syndrome market. Presence of the leading players and increasing availability of funds in this region are likely to support the growth in the coming future.

On the other hand, the Middle East & Africa hold the least share of the market due to limited availability of funds and availability of medical facilities, and poor political conditions in Africa. The Middle East holds the major share in the Middle East & Africa Cowden syndrome market. Kuwait, Qatar, Oman, and South Arabia holds the major share of the Middle East market. However, the African region is expecting a healthy growth due to the presence of a huge opportunity for the development of the market.

And The Europe accounts for the second largest Cowden syndrome market, which is followed by the Asia Pacific. Availability of the funds for research & development and strong government support have driven the market growth. The Asia Pacific is the fastest growing Cowden syndrome market owing to the increasing prevalence of cancer, rapidly developing the economy and increasing government support. India and China are expected to lead the market in this region.

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Laser Therapy Market Growth, Trends and Value Chain 2020-2027

 Laser therapy is a non-invasive medical treatment that uses light of a specific wavelength to treat multiple diseases. Laser therapy is most commonly used to remove tumors or precancerous growths, remove kidney stones, repair a detached retina, treat hair loss, and various cancers. Laser treatment is also used to seal nerve endings after surgery, lymph vessels to reduce swelling, and blood vessels to help prevent blood loss. Lasers have become an essential part of the ophthalmology. In laser-based ophthalmology, a beam of light reshapes the cornea, thereby improves the corneal focusing. It can also be used to create a channel to relieve the intraocular pressure of glaucoma or cauterize tiny hemorrhages. Commonly used lasers in ophthalmology are Nd: YAG LASER, excimer LASER, femtosecond LASER, and others. Increasing prevalence of the diseases like cataract and arthritis is the major driver for the market growth. According to the National Eye Institute, the number of people in the U.S. with cataract is expected to double from 24.4 million in 2010 to 50 million by 2050. Moreover, in 2015, National Eye Institute stated that more than half of the Americans suffer from a cataract related problems in their life span. Moreover, growing demand for aesthetics and rising geriatric population followed by increasing demand for non-invasive procedures wil arket growth during the forecast period.

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The global laser therapy market size is expected to grow at a CAGR of 9.2% during the forecast period.

Segmentation

The global laser therapy market is segmented on the basis of type and application.

On the basis of type, the market is segmented into diode lasers, solid state lasers, gas lasers, dye lasers, and others.

On the basis of application, the market is segmented into dermatology and aesthetics, surgery, dental, and others. The surgery segment is further segmented into urology, ophthalmology, and others.

Regional Analysis

America dominates the global laser therapy market owing to a well-developed healthcare sector. Moreover, huge patient population for medical conditions like arthritis and cataract, drives the market growth. According to the Centres for Disease Control and Prevention, about 78 million U.S. adults aged 18 years or older are projected to have doctor-diagnosed arthritis by 2040. Additionally, changing lifestyle, increasing healthcare expenditure, and growing geriatric population have boosted the growth of the market in America.

Europe is the second largest laser therapy market, which is followed by Asia Pacific. Availability of funds for research, huge patient population, increasing healthcare expenditures, a well-developed healthcare sector and government support for research & development are projected to drive the market growth during the forecasted period. According to the Royal National Institute of Blind People (2016), the number of people living with sight loss are expected to reach 2.7 million by 2030 due to possible cases of refractive error, cataract, glaucoma, and others.

Asia Pacific is the fastest growing region in the global market due to the presence of a huge patient population, continuously developing economies like India and China which are presenting great opportunities to the market. Moreover, growing geriatric population within the region boosts the market growth. According to the Economic and Social Commission for Asia and the Pacific, in 2016 about 12.4% of the population within the region aged 60 or more and this geriatric population is expected to reach 1.3 billion by 2050.

On the other hand, the Middle East & Africa hold the least share in the global laser therapy market due to presence of poor economy and stringent government policies, especially, in the African region. Majority of the market of this region is held by the Middle East due to a well-developed healthcare sector and huge healthcare expenditure.

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Paroxysmal Atrial Tachycardia Market to Witness Widespread Expansion During 2020-2027

 The global paroxysmal atrial tachycardia market is expected to reach USD 10.7 billion by 2023, and the market is projected to grow at a CAGR of ~ 6.5 % during the forecast period 2017-2023.

Paroxysmal atrial tachycardia is irregular heartbeat and is a type of atrial arrhythmia where the episode of arrhythmia begins and ends abruptly. Paroxysmal atrial tachycardia (PAT) is also known as paroxysmal supraventricular tachycardia (PSVT). PAT increases heart rate from 60 to 100 beats per minute (bpm) to between 130 and 230 bpm with infants demonstrating heart rate greater than 220 bpm. PAT is the most common form of tachycardia in infants and children. Symptoms of PAT may include palpitations, lightheadedness, sweating, shortness of breath, chest pain and others. PAT is not usually a life-threatening disorder and the symptoms subside on their own. However, in rare cases, PAT may cause unconsciousness, congestive heart failure, cardiomyopathy and cardiac arrest. Having other heart issues such heart attacks or valve disease increase risk for PAT.

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The cause of PAT are unknown but risk factors include alcohol, caffeine, nicotine, psychological stress, and Wolff-Parkinson-White syndrome. PAT occurs when electrical signals starting in the heart’s atria fire irregularly which affects the electrical signals transmitted from the sinoatrial node. This irregular beating prevents your heart from having enough time to fill with blood before pumping blood resulting in the body not receiving enough blood or oxygen. Women are at a higher risk for PAT than men.
Key Players in the Global Paroxysmal Atrial Tachycardia Market
Some of the key players profiled in the report are Abbott Laboratories, Reliant Pharmaceuticals, BIOTRONIK SE & Co. KG, Boston Scientific Corporation, GlaxoSmithKline plc, GE Healthcare, Glenmark Pharmaceuticals, Koninklijke Philips N.V., ANI Pharmaceuticals, Inc., Medtronic, Inc., Microport Scientific Corporation, St. Jude Medical, Inc., and Siemens AG and others.

The market drivers for global paroxysmal atrial tachycardia diagnosis market are rise in demand due to growing older population, increasing screening, greater emphasis on cardiac treatment, urgency of the paroxysmal atrial tachycardia treatment, rise in risk factors and others. The market restraints are the complications such as risk of bleeding, infections, pain, especially during surgery, high cost of paroxysmal atrial tachycardia treatment, lack of cardiac care infrastructure, and lack of focus on other diseases by the developing regions and others.

Segments
The global paroxysmal atrial tachycardia market has been segmented on the basis of types, condition, diagnosis, drugs, surgery and end user.

Based on the types, the market has been segmented as AV nodal re-entrant tachycardia (AVNRT), AV reciprocating tachycardia (AVRT), and paroxysmal atrial tachycardia.

Based on the diagnosis, the market has been segmented as electrocardiogram (ECG), echocardiogram, blood tests, and electrophysiology study (EPS) and others.

Based on the treatment, the market has been segmented as calcium channel blockers, digoxin, beta-blockers, anti-arrhythmic medications, surgical ablation and others.

Based on the end user, the market has been segmented as hospitals and clinics, research and academics and others.

Regional Analysis
The Americas account for a significant market share owing to high expenditure on the health care especially in the U.S. and Canada. Additionally, the greater number of cardiac procedures due to greater healthcare penetration in the U.S. and Canada drives the paroxysmal atrial tachycardia market. The high concentration of the major hospitals in the developed countries of this region coupled with good reimbursement rates is also adding fuel to the market growth. Moreover, the large share of cardiac procedures especially the cardiac surgery treatment in the returns of hospitals favors the market. The large number of pharmaceutical companies in the U.S. is also a cause for the faster development of paroxysmal atrial tachycardia market in the U.S. The high development of microsurgery field in developed regions such as the U.S. and Europe is a strong driver of the market.

Europe is the second largest market in the world due to growing pharmaceutical industry and healthcare penetration. The European market growth is led by countries such as Germany and France. Germany is expected to be the fastest growing market over the assessment period due to its large pharmaceutical and microsurgery devices industry.

Asia Pacific region is expected to grow rapidly; China and India are likely to lead this market due to the fast growing healthcare sector and large unmet needs over the forecast period. South East Asian countries such as China, India, and Malaysia are projected to contribute highly to the market growth. The growing penetration of healthcare industry in the Asia Pacific region is expected to drive the future paroxysmal atrial tachycardia market in the region. However the low expenditure on cardiac and eye care coupled with the lack of insurance penetration in the developing regions is a dent on the market.

Gulf nations such as Saudi Arabia and the UAE are estimated to drive the Middle East & African market. Other Middle East nations to watch out for are Kuwait, Jordan, Egypt and Iran. The African region is expected to witness a poor growth owing to poor economic and political conditions, and poor healthcare development. Other regions are expected to be laggards due to poor social development and tribal identities such as sub Saharan Africa. The focus of the governments of poor countries on fulfilling basic healthcare relegates the paroxysmal atrial tachycardia market to the background which hampers the development of the market.

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Cancer Biological Therapy Market Insights Analysis 2020-2027

 Market Research Future (MRFR) evaluates that the Cancer Biological Therapy Marke share can touch an impressive USD 82,276.8 Million by 2023-end. MRFR also projects that the global cancer therapeutics market can attain a growth rate of 4.7 % from 2017 to 2023 (forecast period).

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Drivers

Escalating Cancer Cases and Rising Use of Nanotechnology to Boost Growth

Significant burden of rising cancer cases and the surging death rate across the world have been major reasons for the strong growth of the cancer biological therapy market. The World Health Organization (WHO) says that cancer is one of the top five causes of death globally and claimed over 9.5 million lives in 2018 alone. Some key factors that result in cancer development can be the accelerated intake of tobacco and alcohol, which further strengthen the cancer biological therapy industry.

Researchers and vendors in the global cancer biologics market are increasingly making use of nanotechnology to develop more innovative and effective treatment options for patient. This procedure is touted to be a game-changer for cancer diagnosis, while the advancements in materials science, as well as protein engineering, could be huge assets for medical professionals in precise targeting of cancer cells. These innovations are gaining considerable grounds backed by increasing government spending and favorable policies across developed countries.

Opportunities

Rising Education and Awareness Levels to be a Significant Opportunity

Gene therapy has emerged as a lucrative opportunity for the prominent firms in the market, considering the host of benefits compared to other traditional cancer therapies along with the rising advances in this field. The surge in biotechnological funding encouraging extensive R&D activities with respect to cancer gene therapy are expected to be significant cancer biological therapy market trends in the ensuing years.

Restraints

Huge Spending Required on Drug Development to Slow Down Growth

Requirement for substantial funds for effective drug development discourages industry participants, in turn slowing down the market growth.

Challenges

Risks Associated with Anti-Cancer Drug Therapies

In some cases, complications arise from anti-cancer drug therapies, which bring down the success rate of the overall treatment. In view of these risks, the demand for cancer biological therapy could weaken and prove to be a significant challenge over the following years.

Segment Overview

Phase III to Capture the Largest Share

The various phases in clinical trials include phase I, phases II and phases III.  Generally, the clinical trials’ success rate increases from phase I to phase II and lastly phase III, and therefore, the phase III is expected to take the lead in the global market. Phase 3 clinical trials involve huge number of candidates in order to ensure the validity of the result.

Monoclonal Antibodies to Claim the Leading Position

Primary types considered in the MRFR report are interferons, monoclonal antibodies, cancer growth inhibitors, interleukins, colony-stimulating factors and gene therapy. Monoclonal antibodies segment should project the highest growth in the coming years, as these have the ability to target certain proteins present on the cell surface, leading to its escalating use in cancer treatment. Also, greater preference for innovative cancer biological therapies to reduce the risk related to anti-cancer drug therapies will also mean substantial growth for the segment.

Hospitals & Clinics to be the Top End-User

Some of the key market end-users include cancer research centers and laboratories as well as hospitals & clinics. Hospitals & clinics lead the worldwide industry owing to their rising number across developing countries and the availability of a vast range of medical devices for treatment and surgeries. However, there has been striking growth in the number of cancer research centers and laboratories as well, backed by substantial funding by the government and private firms worldwide.

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Eyelashes Enhancing Market to Witness Widespread Expansion During 2020-2027

 Eyelash enhancing serum is a unique formula with lash enhancement, conditioning, moisturizing, and strengthening ingredients that collaboratively works to support and improve the overall appearance of eyelashes. A plenty of temporary lash-lengthening options are available in the market such as mascara and false eyelashes, which are available in the market, but there has been an influx of eyelash serums in stores that promise to strengthen and grow those tiny hairs. These eyelash enhancers have become increasingly popular due to their effective functional feature that turns drab, sparse, and brittle eyelashes into attractive and long eyelashes by the simple process of applying serums to the eyelash area.

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The global eyelashes enhancing agents market is growing moderately due to increasing prevalence of eye inflammations such as madarosis and blepharitis. Additionally, a shift in trend towards the natural eyelash enhancer agent, and continuous uptake of come higher medical dosages cause loss of eyelashes is likely to drive the market growth over the review period.

Breast cancer patients suffer from madarosis due to continuous session of intra-arterial chemotherapy. To cure this disease, a formulation of eyelash enhancer such as bimatoprost is used that maximizes eyelash and minimizes intraocular side effect. In case of blepharitis, there is loss of eyelashes occurs due to the presence of bacteria and oily flakes at the base of eyelashes. Blepharitis is a common disease, especially, among people who have oily skin, dandruff or dry eyes. According to International Journal of Development Research, blepharitis accounted for 700,000 patient visits in the US in 2014. Patients who have blepharitis take eyelash enhancer such as biotin as part of treatment. In some cases, blepharitis also causes loss of eyelashes (madarosis).

However, side-effects of eyelashes enhancer agents may affect the growth of the global eyelashes enhancing agents market, negatively.

The global eyelashes enhancing agents market is expected to grow at a CAGR of 5.83% during the forecast period 2017-2023.

Segmentation                                                                                                                                      

The global eyelashes enhancing agents market is segmented on the basis of types, application, and content.

On the basis the types, it is segmented into curling, lengthening, volumizing, and others.

On the basis of the application, it is segmented into repairing damaged eyelashes, nourishing, and others.

On the basis of the content, it is segmented into bimatoprost, lash-building serum, skincare ingredients, herbal remedy, isopropyl cloprostenate, enhancer serum, and others. The skincare ingredients are further segmented into polypeptides, biotin, panthenol, and others.

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Perfusion Market to Witness Widespread Expansion During 2020-2027

 Perfusion is a process of delivering oxygenated blood to all tissues. This technique is used in cardiac surgery where perfusion experts employ artificial blood pumps to thrust patients' blood through their body tissue by replacing the function of the heart while the cardiac surgeon operates. Perfusion can be used as chemotherapy technique for the treatment of melanoma occurring in arm or legs. With the help of this technique, flow of blood to and from the limb is stopped for a while by creating a band, and anticancer drugs are put directly in blood of the limb. This helps patients to receive a high dose of drugs in the area where the melanoma had occurred.    

Poor perfusion causes numerous severe health problems such as deep vein thrombosis and coronary artery disease. It has been observed that during major surgeries such as cardiothoracic surgeries and organ transplant, maintenance of perfusion is vital and to maintain this many preservation methods are being used. The two most important methods are machine perfusion (MP) and static cold storage (SCS). Although SCS is a highly adopted process for preservation, it is inefficient to maintain normal functioning of organs at high-risk. Hypothermic machine perfusion (HMP) has emerged as an effective solution to curb such problems. Every year more than one hundred thousand perfusion procedures are being performed around the globe.

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Rising number of chronic diseases cases such as cardiac diseases, liver and kidney diseases often leads to organ transplant and is one of the major driver of the global perfusion market. Moreover, rising cases of organ failure due to other factors such as improper diet, smoking and consumption of alcohol has led to the demand of effective perfusion systems. As per National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), more than 661,000 Americans have kidney failure which is a major driving force for the global perfusion market. However, lack of awareness regarding perfusion systems in developing countries can limit the growth of this market.

The global perfusion market trends are growing steadily and is expected to continue its growth during the forecast period. Global perfusion market is expected to grow at the CAGR of 4.1% during the forecast period and is estimated to reach around USD 1,527 million by 2023.

Segments Global perfusion market has been segmented on the basis of type which comprise of cardiopulmonary bypass, extracorporeal membrane oxygenation, isolated limb perfusion and others. Cardiopulmonary bypass is further sub-segmented into heart-lung machines, oxygenators, perfusion pumps, monitoring systems, cannulas, and other components.

On the basis of application, it is segmented into lungs, heart, liver, kidneys and others. On the basis of device type, the market has been segmented into hypothermic machine perfusion, normothermic machine perfusion and others. On the basis of end user, it is segmented into hospital, specialty clinics, medical research centers, academic institutes, and others.

Regional Analysis of Global Perfusion Market                

Considering the global scenario of the market, the Americas is the largest market of perfusion. The Americas mainly includes North America and Latin America. North America is a dominating region across the global market. Some major factors like technological advancement and growing number of organ transplants are major driving factors for the growth of the global perfusion market. Europe is the second highest revenue generating region in the global perfusion market. Europe is mainly divided into Eastern Europe and Western Europe. More developed countries of Western Europe like Germany, France and UK are holding major market share while the market in East European countries are also growing significantly. Due to the developing healthcare infrastructure, increasing healthcare expenditure, and growing adoption of new techniques for perfusion and organ preservations has led to the fastest growth of the Asia Pacific perfusion market. Middle East & Africa is expected to grow slow growth in this market. Middle Eastern countries like UAE and Saudi are dominating this market, it is mainly due to availability of top class medical facilities, high income and government support to improve public health.

Key Players of Global Perfusion Market Some of the key players in this market are Getinge AB (Sweden), Medtronic (Ireland), LivaNova PLC (U.K.), Terumo Medical Corporation (Japan), XENIOS AG (Germany), Lifeline Scientific, Inc. (U.S.), XVIVO Perfusion (Sweden), Repligen Corporation (U.S.), Spectrum Laboratories, Inc. (U.S.), Merck KGaA (Germany), Harvard Bioscience, Inc. (U.S.), Ala Science (U.S.) and others.

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