Cardiopulmonary Resuscitation Market Growth, Trends and Value Chain 2020-2027

 Global Cardiopulmonary Resuscitation Market size was valued at USD 1,603.16 Million in 2019 and is expected to register a CAGR of 10.50% during the forecast period of 2020 to 2027.

Cardiopulmonary resuscitation (CPR) is a lifesaving technique useful in many emergencies, including a heart attack or near drowning, in which someone's breathing or heartbeat has stopped. During a cardiac arrest, due to an insufficient supply of blood, the heart stops beating. In such conditions, blood circulation vital to sustaining life can be provided by constantly compressing the heart through a physical force applied to the patient’s chest. This rescue technique is termed cardiopulmonary resuscitation (CPR), which is employed in emergencies or conditions to protect the patient from fatal myocardial infarction or brain damage.

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Global Cardiopulmonary Resuscitation Market is mainly driven by the increasing prevalence of heart and respiratory diseases, rising geriatric population, rise in government initiatives, increasing global incidence of cancer, and growing product approvals by major players. People worldwide are living longer. According to the World Health Organization, by 2050, the world’s population aged 60 years and older is expected to be 2 billion, up from 900 million in 2015. By 2050, there will be almost this many (120 million) living in China alone, and 434 million people in this age group worldwide. By 2050, 80% of all older people will live in low- and middle-income countries.

Market Dynamics

Heart disease is the leading cause of death in men and women globally. According to the American College of Cardiology, approximately every 40 seconds, an American will have a myocardial infarction. It further stated that in 2017, emergency medical services-assessed out-of-hospital cardiac arrest occurred in an estimated 356,461 Americans; emergency medical services treatment was initiated in 52%. The initial recorded cardiac rhythm was ventricular fibrillation, ventricular tachycardia, or shockable by an automated external defibrillator in only 18.7%. Adult survival to hospital discharge was 10.4%; 8.4% had good functional status at discharge. Furthermore, according to NHS England, the respiratory disease affects one in five people and is the third-biggest cause of death in England (after cancer and cardiovascular disease). According to a new Tulane University study published in The Lancet, chronic obstructive pulmonary disease (COPD) is widespread in China, with 8.6% of the country's adult population with almost 100 million people suffering from chronic lung disease. In addition, as per the World Health Organization, it is estimated that 54% of deaths from noncommunicable diseases in the Eastern Mediterranean Region are due to cardiovascular diseases. Deaths attributed to cardiovascular diseases (of total deaths) range from 49% in Oman to 13% in Somalia. The prevalence of cardiovascular diseases is due to sedentary lifestyles and common risk factors, such as hypertension (ranging from 28% in the UAE to 41% in Libya and Morocco); diabetes (ranging from 4% in the Islamic Republic of Iran to 19% in Sudan) and hypercholesterolemia (ranging from 14% in Lebanon to 52% in the Islamic Republic of Iran). Effective CPR can improve the survival rate of patients with cardiac and respiratory diseases. Application of CPR immediately can increase the survival rate of victims significantly. A study by the American Heart Association states that 70% of Americans feel helpless in cardiac emergencies as they are not aware of administering CPR.

The International Liaison Committee on Resuscitation (ILCOR) launched the first global “World Restart a Heart (WRAH)” initiative in 2018. The aim was to increase public awareness and improve the rates of bystander cardiopulmonary resuscitation (CPR) for victims of cardiac arrest.

Segmentation

Global Cardiopulmonary Resuscitation Market has been divided based on Product Type, Compressor Type, Application, and End User.

On the basis of Product Type, the market is bifurcated into piston CPR devices, load-distributing band (LDB), active compression-decompression (ACD) devices and impedance threshold device, extracorporeal techniques and invasive perfusion devices, and others. The piston CPR devices segment is expected to register the highest CAGR of 11.57% during the forecast period.

On the basis of compressor type, the market is bifurcated into manual CPR and automatic mechanical CPR. The automatic mechanical CPR segment accounted for a larger market share with a value of USD 101.6 million in 2019.

On the basis of application, the market is bifurcated into emergency departments, coronary & intensive care units, organ transplant facilities, air medevac units, and EMT rescue units. The EMT rescue units segment is expected to register the highest CAGR of 12.71% during the forecast period owing to the rise in the availability of a skilled workforce across the globe.

On the basis of end user, the market is bifurcated into hospitals and clinics, cardiac catheterization laboratories, organ transplant units, and others. The hospitals and clinics segment accounted for the largest market share at a value of USD 136.1 million in 2027. This large share can be attributed to the growing awareness of many cardiovascular disease and arrhythmia.

Regional Analysis

Global Cardiopulmonary Resuscitation Market, based on region, has been divided into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is expected to command the largest market share due to the rise in the prevalence of lifestyle diseases and heart diseases.

Europe held a substantial share in the global market. This can be attributed to the technological advancements, high disposable income, growing geriatric population, and favorable regulatory framework. According to the British Heart Foundation, around 7 million people are living with heart and circulatory disease in the UK, where 3.4 million are men and 3.5 million women.

Asia-Pacific is expected to command the third-largest share of the global market owing to the growing geriatric population, increasing chronic diseases, and elevated utilization of medical devices in healthcare. Rising awareness regarding medical devices and key measures taken by government bodies in the adoption of monitoring devices and improving emergency paramedical services are the other key drivers of the market in Asia-Pacific.

The cardiopulmonary resuscitation market in Middle East & Africa is expected to exhibit steady growth during the review period due to the increasing number of heart & respiratory diseases and rapidly developing healthcare infrastructure. For instance, according to the Dubai Health Authority, nearly 30% of the UAE population suffers from heart disease, which has emerged as a major killer; 32% of people suffer from high blood pressure, with high stress being a major contributor.

Key Players

The Prominent Players in the Global Cardiopulmonary Resuscitation Market are Stryker, Nihon Kohden Corporation, ZOLL Medical Corporation, Koninklijke Philips N.V., Vyaire Medical, Inc., General Electric Company, CPR Medical Devices, Inc., Michigan Instruments, Corpuls, SCHILLER, and Medtronic.

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Smart Insulin Pens Market to Witness Widespread Expansion During 2020-2027

 Market Research Future (MRFR) confirms that the Smart Insulin Pens Market size 2020 was worth USD 72.97 Million in 2019, thanks to the escalating cases of diabetes, surge in product approvals and launches, expanding geriatric population and more.

COVID-19 Analysis

The COVID-19 outbreak has been an impactful event, with the diabetes community facing a host of challenges, since SARS-CoV-2 affected individuals with diabetes are more prone to developing adverse symptoms and have a greater fatality rate compared to patients with no comorbidities. The novel coronavirus and the subsequent lockdown have also affected the diabetes community in the form of drug repurposing, weakened manufacturing processes and shortage of essential medical devices like smart insulin pens.

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However, studies are being conducted and notable advancements are taking place in the diabetes space, with clinical needs of patients garnering the focus of the healthcare industry. Following the pandemic, companies have been focusing on enhancing their products’ durability, tolerability, ease of compliance, hypoglycemia avoidance, as well as on strengthening their supply chains to close the demand and supply gap, which can be favorable for the smart insulin pens market, despite the pandemic.

Market Dynamics

Drivers

Alarming Escalation in Diabetes Cases to Boost Growth

One of the key factors working in favor of the global market is the escalating pool of diabetics in light of surge in obesity, sedentary lifestyles and aging. Obesity has emerged one of the top factors leading to diabetes among individuals. The key risk factors like being overweight and obesity are the primary links to diabetes cases, which have been growing at epidemic proportions. As a result, the colossal population suffering from diabetes is fostering the smart insulin pens market size worldwide.

A major trend observed in the market is the rising preference for refillable insulin pen, Bluetooth-enabled smart insulin pens and USB connected insulin pens. These insulin pens are extensively used in devices diabetic patients to administer insulin, and are primarily prevalent in developed nations like the United States.

Opportunities

The surging preference for homecare settings, especially among the geriatric pool, has emerged as a lucrative opportunity for smart insulin pens market manufacturers. The home care segment has gained prevalence owing to the mounting awareness level about diabetes care combined with the soaring use of insulin delivery devices for home use. The use of smart insulin pens at home helps reduce hospital visits, thereby saving money and time. Advanced devices such as smart insulin pens are compact and portable and rising access to these among patients is resulting in a greater preference for self-care diabetes management.

Restraints

Strict Product Approval Process to be a Major Growth Restraint

Strict government regulations and rules that govern the product approval process could be a major restraint in the market growth during the review period. stringent government rules are discouraging companies to spend on product development, which can be detrimental for the global market.

Challenges

High Costs of Smart Insulin Pens to be a Huge Challenge in Underdeveloped Nations

High costs associated with smart insulin pens and other diabetes treatment options could be a key challenge for the global industry in the years ahead. Underdeveloped regions such as Africa suffer owing to substandard healthcare infrastructure and poor reimbursement scenario, deterring patients to seek treatments and do not have access to advanced devices such as smart insulin pens. Therefore, device manufacturers are not able to observe any sales and this has emerged as a huge challenge for them over the years.

Cumulative Growth Analysis

Global Market to Procure a Decent CAGR as Product Demand Escalates

Smart insulin pens market can record a decent CAGR of 10.77% between 2020 and 2027 (evaluation period), reveals MRFR. The market growth rate is primarily bolstered by the amplified demand for smart insulin pens, in view of the provision of accuracy with respect to insulin dosing and their simple functioning. Mounting number of initiatives by public and private firms is also fostering the insulin pens market share across the globe.

Segment Overview

Smart Pens Segment Soars at a Rapid Pace

The main product types of insulin pens are connecting device and smart pen.  Smart pens will be the fastest growing segment at a rate of 10.98% over the forecast period, as a result of the heightened adoption rate and significant popularity among patients due to user-friendly design. With insulin pens brands focusing on innovations and technical advances, the segment is bound to note further growth.

Hospitals/Retail Pharmacies Continue to Dominate the Market

The top market end-users are hospital/retail pharmacies as well as online. The hospital/retail pharmacies segment has remained in the lead since 2019, accruing a valuation of USD 47.97 million that same year owing to the fact that hospitals are go to spots for diabetic patients seeking consultation and treatment.

Regional Analysis

America to Take the Lead in the Global Market

The Americas can most likely take the lead in the global market over the following years, thanks to the rapid uptake of advanced diagnostic measures and medicines by the target patients. The region also has a well-established medical device and healthcare industry, which also benefits the market. Collaborations, partnerships and brand promotion are some of the top strategies employed by American players, who also focus on innovations in disease management and spreading awareness about products among patients and medical professionals. The surge in extensive R&D activities paired with the escalating use of smart insulin pens in supplements, medical application, skin care and beverages also contribute to the market expansion in the region. The market for smart insulin pen in Canada is also gaining momentum, with the rising prevalence of inactive lifestyle and growing cases of obesity.

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Market Research Future Releases New Report on the Global EPharmacy Market 2027

 Global ePharmacy Marke t size was valued at USD 62,587.0 Million in 2019 and is expected to register a CAGR of 12.5% during the forecast period of 2020 to 2027.

An E-Pharmacy is a pharmacy that operates over the internet and sends orders to customers through mail or shipping companies. The growth of the online pharmacies can be acknowledged from the following examples. The electronic prescription service (EPS) was aimed at rolling out in November 2019, according to the Department of Health, UK, claiming it would save the NHS through increasing efficiencies, reducing the amount of paper processing required, and reducing prescribing errors. In January 2019, Ping An Good Doctor, a one-stop healthcare ecosystem platform from China, announced that it had placed its One-minute Clinics across 8 provinces and cities in China and signed service contracts for nearly 1,000 units, providing healthcare services to more than 3 million users. Every One-minute Clinic has more than 100 categories of common drugs, all of which are cryogenically refrigerated to ensure their quality. New York in 2016 took the step of requiring prescribers to use electronic transmission of prescriptions to pharmacies.

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Factors such as the convenience provided in the delivery of medication discounted price, and laws favoring the adoption of ePharmacy, are driving the growth of the ePharmacy market. Additionally, rising investment for small companies is also driving the growth of the ePharmacy market. However, the rising number of counterfeit online pharmacies is posing as a challenge for the growth of the market.

Market Dynamics

An online pharmacy, internet pharmacy, or mail-order pharmacy is a pharmacy that operates over the Internet and sends orders to customers through mail, shipping companies, or online pharmacy web portal. Key players operating in the ePharmacy market to provide cost-efficient and timely services to survive and succeed in an intensely competitive and growing market environment.

A shift in consumer preference toward the online purchase of medicines and rising penetration of high-speed internet is driving the growth of the market. An increase in the number of online pharmacies and the booming pharmaceutical industry further anticipates the market growth. As of January 2020, 50+ start-ups are operating in e-Pharmacy space in India, which provides quality and affordable medicines to about 5,000,000 patients per month across the country. The number of ePharmacy has grown with the rising investment in the sector. Stockholm-based online pharmacy Meds raised USD 5.7 million in a round led by Inbox Capital.

E-Pharmacy improves purchaser's comfort and access, this will above all advantage endless old-age patients living in family units, and patients who are not in a condition to go out to discover a drug store. Globally, the population aged 65 and over is growing faster than all other age groups. According to data from World Population Prospects: the 2019 Revision, by 2050, one in six people in the world will be over age 65 (16%), up from one in 11 in 2019 (9%). The number of people aged 65 or more living in nursing homes is huge and suffering from chronic conditions such as diabetes, arthritis, eye diseases, or cognitive impairment. About 1.4 to 1.5 million people were living in nursing homes in the state according to research conducted by the Ohio State University Wexner Medical Center. The large number of geriatric populations suffering from chronic disease is expected to fuel market growth.

Segmentation

Global ePharmacy Market has been divided based on Drug Type, Operating Platform, and Business Model.

The market, based on Drug Type, has been segregated into prescription drugs and over the counter (OTC) drugs. The prescription drugs segment accounted for the largest market share of 55.6% in 2019. This largest share can be attributed to its preference as compared to over the counter drugs.

The market, based on operating platform, has been segregated into app and website. The app segment accounted for the largest market share of 57.6% in 2019. The rising number of retail pharmacies launching apps for the delivery of products globally is the key factor owing to the growth of this segment.

On the basis of business model, the market is segregated into the marketplace, pharmacy, and direct. The marketplace segment accounted for the largest market share with a value of USD 33,222.2 million in 2019 due to the increasing number of customers buying medications and refilling it online.

Regional Analysis

Global ePharmacy market, based on region, has been divided into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas are likely to dominate the global ePharmacy market owing to the presence of major manufacturers, raising awareness, and rising product launches by major players in the region. In 2019, the Americas accounted for the largest market share of 48.9% in the global ePharmacy market. This large share is majorly attributed to the presence of major ePharmacy players, and reliance of the general population on the online delivery of consumable goods. According to the most recent Statistics Canada report, retail e-commerce sales reached USD 2.3 billion in November, accounting for 4.2% of total retail trade. On a year-over-year basis, retail e-commerce increased by 20.1%, while total unadjusted retail sales rose 1.1%.

Europe held a substantial share in the global ePharmacy market. The ePharmacy market in Europe is expected to propel during the forecast period, owing to factors such as increasing online orders, the rapid increase in e-commerce, rising prevalence of chronic diseases, an increase in the geriatric population, and well-developed IT infrastructures. For instance, according to NCBI in Europe, the amount of online pharmacies is continuously increasing, while the amount of physical pharmacies is slightly decreasing (21,602 pharmacies in the year 2008) with only 20,441 operating public pharmacies in 2015. Glovo is a Spanish start-up founded in Barcelona in 2015. It is an on-demand courier service that purchases, picks up, and delivers products ordered through its mobile app. In Spain, the company observed a 60% growth in pharmaceutical orders during the pandemic of coronavirus. As of April 2020, it has provided around 133,000 masks, 71,000 pairs of gloves, and 2,500 liters of hand sanitizer gel worldwide through couriers.

The fast growth of the Asia-Pacific region is due to rising diabetes cases and the increasing per capita income along with government initiatives to enhance the quality of healthcare. China, India, and Australia have a lucrative market for ePharmacy due to the growing older population. Moreover, according to the report published by the United Nations in 2015, the number of older people aged 60 years or above in the world is predicted to grow by 56% between 2015 and 2030. Nearly 66% of the older population out of the total global population would also reside in the Asia-Pacific region. The increasing geriatric population will lead to an increase in metabolic disorders, which will, in turn, increase the patient population in need of delivery of medications and lead to growth in the ePharmacy market.

The market growth in the Middle East & Africa can be attributed to the novel public-private partnerships (PPP) business model, developing healthcare infrastructure, and government support. South Africa's Gauteng department of health in partnership with Right to Care and Right ePharmacy launched a groundbreaking "ATM pharmacy" also known as pharmacy dispensing unit (PDU). Right ePharmacy is an innovative, strategic solution provider for the dispensing, distribution, and collection of medicine. Right ePharmacy is the center of excellence for its parent company, Right to Care, spearheading disruptive innovation, and enhancing differentiated models of pharmaceutical care in Africa. So far 16 pharmacy dispensing units have been installed near shopping malls in Alexandra, Soweto, and Diepsloot townships in Johannesburg, and have served thousands of patients between March and the end of May. During 2018, medication was picked up 19,352 times from PDUs.

Key Players

The Prominent Players in the Global ePharmacy Market are 3M, B. Braun Melsungen AG, Baxter International INC, Smith & Nephew Plc, Cardinal Health, Coloplast Corp., ConvaTec Group Plc, Integra Lifesciences Holdings Corporation, Mölnlycke Health Care AB and Avery Dennison Corporation.

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Vitiligo Treatment Market Growth, Trends and Value Chain 2020-2027

 Market Forecast

Vitiligo Treatment Market is expected to cross USD 1.84 Billion by 2025 at a CAGR of 5.6%.

Market Synopsis

Vitiligo is a pigmentation disorder in which the skin's pigment-making cells known as melanocytes are lost or destroyed. As a result of which, well-defined white patches appear on the skin. Patches may occur on one section or all over the body and later may join together.

Market Influencer

Increasing prevalence of investments by government bodies on healthcare infrastructure is positively influencing the global vitiligo treatment market.

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The growth of the global vitiligo treatment market is driven by various factors such as emerging therapies for skin disorders, increasing healthcare expenditure, lifestyle changes. However, the lack of skilled professionals is expected to curb the growth of the global vitiligo treatment market.

Several market players currently dominate the global vitiligo treatment market. The key players are involved in product launches and strategic collaborations to strengthen their market positions. For instance, Incyte Corporation reported positive results from the study of ruxolitinib cream which is in phase 2. This topical cream is suggested for vitiligo treatment.

Segmentation

The global vitiligo treatment market has been segmented based on type, treatment type, and end-user.

The market, based on type, has been divided into non-segmental and segmental. On the basis of treatment type, the market has been segmented into therapy, surgery, medication, and others. The therapy is further segmented into light therapy and depigmentation. The surgery is segmented into skin grafting, blister grafting, and micro-pigmentation. The medication is segmented into topical corticosteroids and immunosuppressive drugs.

The end-user segments of the market consist of hospitals, aesthetic clinics, and others. The hospitals and clinics segment is expected to hold the largest share of the market as these centers are the primary locations for patients receiving treatment and surgery.

Key Players

Some of the Key Players in the Global Vitiligo Treatment Market are Bausch Health Companies Inc. (Laval, Quebec), STRATA Skin Sciences (Horsham, PA), Reddy’s Laboratories Ltd. (India), Allergan, Inc. (Dublin, Coolock), Clinuvel Pharmaceuticals Limited (Melbourne, Victoria), Astellas Pharma Inc. (Northbrook, IL), Novartis AG (Basel, Basel-Stadt), Eli Lilly Company (Indianapolis, Indiana), Incyte Corporation (Wilmington, Delaware),  AstraZeneca AB (Cambridge, Cambridgeshire), Epizyme, Inc. (Cambridge, MA), Pfizer Inc. (New York),and Baxter International Inc. (Deerfield, Illinois)

Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.

The Americas is expected to be the largest market owing to the significant investments by healthcare and medical regulatory bodies in vitiligo treatment to deliver quick medical aid to patients. The vitiligo treatment market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The European vitiligo treatment market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The vitiligo treatment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing number of patients with vitiligo and increasing mergers & acquisitions among the market players are boosting the Asia-Pacific region. The vitiligo treatment market in the Middle East & Africa has been divided into the Middle East and Africa.

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Biopharmaceuticals Market to Witness Widespread Expansion During 2020-2027

 Market Forecast

Biopharmaceuticals Market is expected to hold a value of USD  471,021.1 Mn by 2027 at a CAGR of 9.13%.

Biopharmaceuticals Market Synopsis

Biopharmaceuticals are medical drugs produced using biotechnology. Biopharmaceuticals can be proteins (including antibodies), nucleic acids (DNA, RNA, or antisense oligonucleotides) that are used for therapeutic or in vivo diagnostic purposes. These are produced by various means, including direct extraction from a native (non-engineered) biological source. The first such biopharmaceutical approved for therapeutic use was recombinant human insulin (RHI, trade name Humulin), which was developed by Genentech and marketed by Eli Lilly and Company in 1982. Growing market demand for biopharmaceuticals, rising investment by major companies on research & development of biopharmaceuticals, the high incidence rate of chronic diseases, and increasing acceptance for biopharmaceuticals due to their ability to treat previously untreatable diseases is expected to drive the market growth. As of September 2019, approximately six in 10 adults in the US suffer from a chronic disease. Moreover, rising geriatric population and increasing technological advancements are also anticipated to fuel the market growth.

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Biopharmaceuticals Market Influencer

The involvement of major pharmaceutical companies such as Abbvie Inc., Eli Lilly and Company, and Novartis AG are positively influencing the market growth.

Biopharmaceuticals Market Drivers

• Increasing investment by major companies in biopharmaceuticals research & development (R&D)

• Increasing acceptance for biopharmaceuticals due to their ability to treat previously untreatable diseases

• The high incidence rate of chronic diseases is increasing the demand for biopharmaceuticals, hence driving the market growth. As of 2019, nearly 45% of Americans suffer from a chronic disease.

• Rising geriatric population. As of 2019, one in 6 people in the world is aged more than 65 years.

• Increasing technological advancements

Biopharmaceuticals Market Restraints

• Stringent government regulations
• Availability of low-cost biosimilars
• Risk of side-effects associated with biopharmaceuticals

Biopharmaceuticals Market Segmentation

By Product Type

• Monoclonal Antibodies: The largest segment of the market. Researches carried out with the help of monoclonal antibodies is increasing. Monoclonal antibodies are manufactured using identical immune cells that are clones of a unique parent cell.

• Recombinant Growth Factors: They are a group of proteins that stimulate the growth of the cell. These are further segmented into erythropoietin and granulocyte colony-stimulating factor (G-CSF). Erythropoietin is a type of hormone that is produced by the kidneys. G-CSF is a type of glycoprotein that can stimulate the bone marrow to produce granulocytes and stem cells and ultimately release them in the bloodstream.

• Purified Proteins: These can be further segmented into four subsegments—leukemia inhibitory factor, P53 protein, P38 protein, and other purified proteins. Leukemia inhibitory factor or LIF is a type of interleukin 6 class cytokine that can affect the cell growth by inhibiting differentiation. P53 is a tumor protein, which is an isoform of a protein encoded by homologous genes in various organisms. P38 protein is a class of mitogen-activated protein kinases that are responsive to cytokines, ultraviolet irradiation, heat shock, osmotic shock, and other stress stimuli.

• Recombinant Proteins: They are made from cloned DNA sequences that usually encode a protein or an enzyme with known function. These can be further divided into serum albumin, amyloid protein, defensin, transferrin, and others. Serum albumin is found in the blood and is the most abundant protein found in the human blood plasma. Amyloid proteins are aggregates of proteins that become folded into a particular shape and can allow many copies of that protein to stick together, forming fibrils. Defensins are small cysteine-rich cationic proteins that function as host defense peptides. Transferrin are iron-binding blood plasma glycoproteins that have the ability to control the level of free iron in biological fluids.

• Recombinant Hormones: They are produced from fragments of growth hormone and human placental lactogen.

• Vaccines: They are a type of biological preparation that can protein active acquired immunity against a particular disease. Vaccines have been further segregated into recombinant vaccines, conventional vaccines, and others. Recombinant vaccines are produced using recombinant DNA technology. They have been further divided into cancer vaccines, malaria vaccines, Ebola vaccines, hepatitis B vaccines, tetanus vaccines, diphtheria vaccines, cholera vaccines, and others. Conventional vaccines act as an immunological base to fight against the most porcine diseases. These are further segmented into polio vaccines, pox vaccines, and others. Vaccines are the fastest-growing segment owing to rising awareness regarding chronic diseases.

• Synthetic Immunomodulators: They are a type of medication that is used to help regulate or normalize the immune system. These are further segmented into cytokines, interferons, interleukins; tumor necrosis factor (TNF); and others.

• Others: This segment includes recombinant enzymes allogenic & autologous products and acellular products.

Biopharmaceuticals Market By Application

• Oncology: The largest segment owing to the rising prevalence of cancer. There were 1,735,350 new cases of cancer in the US in 2019.

• Inflammatory and Infectious Diseases: Infectious diseases include cholera, diphtheria, and typhoid. Inflammatory conditions include tuberculosis, rheumatoid arthritis, and sinusitis.

• Autoimmune Disorders: These include diseases such as inflammatory bowel disease, multiple sclerosis, and diabetes.

• Metabolic Disorders: These types of disorders occur when abnormal chemical reactions in the body hamper the normal metabolic process.

• Hormonal Disorders: These include various endocrine disorders such as adrenal insufficiency disorder and hyperthyroidism.

• Disease Prevention: Vaccines are the biopharmaceuticals used for the prevention of chronic diseases.

• Cardiovascular Diseases: These include coronary heart disease, arrhythmia, and peripheral artery disease.

• Neurological Diseases: These include diseases such as Parkinson’s disease and epilepsy. The rising prevalence of neurological disorders is expected to account for the fastest growth of the segment. In the US, 1.8% of the population have been suffering from active epilepsy as of 2016.

• Others: Other applications of biopharmaceuticals include blood disorders and other rare disorders.

Biopharmaceuticals Market By Region

• Americas: The largest regional Biopharmaceuticals Market. The prevalence of chronic diseases, such as cancer, is high in the Americas. Approximately 9.6 million people died suffering from cancer as of September 2019. Moreover, the presence of significant biopharmaceutical companies such as Pfizer, Inc., Amgen Inc., Eli Lilly and Company, and Bristol Myers Squibb Company is expected to drive the market growth.

• Europe: Increasing geriatric population, well-developed healthcare infrastructure, and high prevalence of neurological diseases are expected to drive the market growth.

• Asia-Pacific: The fastest-growing regional biopharmaceuticals market. Asia-Pacific is seeing a surge in the number of people suffering from diseases such as diabetes and cancer. Furthermore, the region has a supportive regulatory framework for the approval of biopharmaceuticals, which drives market growth.

• Middle East & Africa: The biopharmaceuticals market is expected to show significant growth due to the rising patient population suffering from various chronic diseases. Middle Eastern market is expected to show more growth as compared to the African market, owing to the presence of developed countries such as Saudi Arabia and Oman.

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Global Gene Therapy Market size and forecast, 2020-2027

 According to MRFR analysis, the global gene therapy market is expected to register a CAGR of 40.7% during the forecast period of 2019 to 2025 and was valued at USD 524 million in 2018.

Gene therapy is a technique in which a piece of DNA is incorporated into the cell via a vector. The key players are investing in the manufacturing of cell and gene therapy treatments due to its target specificity. The gene therapy is mainly of two types, somatic gene therapy, and germline gene therapy, depending on the type of cells its targets.

The growth of the global gene therapy market is attributed to various factors such as robust product pipeline, increasing investment by key players, and high prevalence of target diseases and demand for innovative medication. However, the high cost of product development and stringent regulatory policies are expected to curb the growth of the global gene therapy market. The global gene therapy market is currently dominated by several market players. The key players are involved in product launches and strategic collaborations to strengthen their market positions.

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Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is expected to be the largest market owing to the increasing prevalence of gene therapy and rising per capita healthcare expenditure. The gene therapy market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The European gene therapy market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The gene therapy market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing number of patients and raising awareness about the treatment methods, the market in Asia-Pacific is expected to be the fastest-growing. The gene therapy market in the Middle East & Africa has been divided into the Middle East and Africa.

Segmentation

The global gene therapy market has been segmented based on product, indication, and end user.

The market, based on product, has been divided into kymriah, luxturna, yescarta, zolgensma, strimvelis, zynteglo, imlygic, and others.

The global gene therapy market has on the basis of indication is segmented, into oncology, genetic diseases/ disorders, and others. The oncology segment is expected to hold the largest market share and to be the fastest-growing segment due to high prevalence of cancer and robust pipeline for cancer gene therapy.

The end-user segments of the market are hospitals & clinics, specialty treatment centers, and others. The hospitals & clinics segment is expected to hold the largest market share due to increasing number of hospitals. Also, hospitals are generally the first treatment choice for diseases.

Key Players

Some of the key players in the global gene therapy market are Amgen, Inc. (US), Novartis AG (Switzerland), Spark Therapeutics, Inc. (US), Gilead Sciences, Inc. (US), uniQure N.V. (Netherlands), Orchard Therapeutics plc (UK), Celgene Corporation (US), Bristol-Myers Squibb Company (US), Thermo Fisher Scientific Inc. (US), CEVEC (Germany), and Lonza (Switzerland).

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Nephrectomy Market Growth, Trends and Value Chain 2020-2027

 Nephrectomy Market is expected to register a CAGR of 4.80% and was valued at USD 4,470.17 Million in 2018.

Nephrectomy is a surgical procedure performed to remove the kidney or a part of it. Nephrectomy is of two types, namely, radical nephrectomy in which the entire kidney is removed and partial nephrectomy where a part of the kidney or the diseased tissues is removed as a process of the treatment. Most frequently, a nephrectomy is done to treat kidney cancer or to remove a noncancerous tumor during urological surgery. The demand for nephrectomy is increasing due to the increasing prevalence of kidney cancer and chronic kidney diseases, the rising number of laparoscopic nephrectomy procedures, and increasing awareness about organ (kidney) transplant. These factors are expected to fuel the growth of the global nephrectomy market. However, risks and complications of the nephrectomy surgery and high cost of the procedure are anticipated to hamper the market growth.

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Market Dynamics

Kidney cancer is a disease in which the healthy cells of one or both kidneys start proliferating in an uncontrolled manner and form lumps (called a tumor). In chronic kidney disease (CKD), also known as chronic renal disease, chronic renal failure, or chronic kidney failure, the problems are kidney-related that result to cause slow and progressive loss of kidney function over a period and eventually results in permanent kidney failure. The main causes of kidney diseases are diabetes and high blood pressure.

For instance, the National Kidney Foundation, Inc. reported that chronic kidney disease (CKD) is one of the leading causes of death in the US and also stated that around 75% of kidney failure was caused due to diabetes and high blood pressure between 2014 and 2016. According to the World Health Organization 2018 fact sheet, 422 million people were reported to have diabetes in 2014 across the world. The increasing prevalence of diabetes is leading to cause kidney problems and is thus driving the nephrectomy market.

Similarly, the awareness and demand for organ (kidney) transplant is likely to drive the market growth. According to the US Government Information on Organ Donation and Transplantation, 21,167 kidney transplants took place in 2018 in the US. Hence the demand for organ transplants is fueling the growth of the worldwide nephrectomy market.

Segmentation

The Global Nephrectomy Market has been divided based on procedure, indication, end-user, and region. The market, based on procedure, has been segregated into open nephrectomy, laparoscopic nephrectomy, and robot-assisted laparoscopic surgery. Based on indication, the nephrectomy market has been divided into kidney cancer and other kidney diseases. On the basis of end-user, it is bifurcated into hospitals & clinics, surgical centers, and others.

Regional Analysis

The Global Nephrectomy Market, based on region, has been divided into the Americas, Europe, Asia-Pacific, and Rest of the World (RoW). The Americas are likely to dominate the global nephrectomy market. The increasing prevalence of kidney cancer in the region, high prevalence of chronic kidney diseases, and growing development in diagnostics would drive the growth of the nephrectomy market in this region. Moreover, according to the American Cancer Society, it is estimated that about 73,820 new cases of kidney cancer (44,120 in men and 29,700 in women) are likely to occur in 2019. Also, kidney cancer is among the ten most common cancers in both men and women. Hence, the market for nephrectomy is expected to grow in the Americas.

Europe held a substantial share in the global nephrectomy market. This can be attributed to the increasing incidence and prevalence of cancer, and public policies & reimbursement procedures in this region are expected to boost the growth of the market in this region.

Asia-Pacific is estimated to be the fastest-growing region in the global market. This is due to the increasing R&D funding by developing countries and the development of the healthcare sector.

The nephrectomy market in Rest of the World is expected to witness steady growth during the review period due to limited access and healthcare affordability among the population.

Key Players

The Prominent Players in the Global Nephrectomy Market are KARL STORZ SE & Co. KG (Germany)., Olympus Corporation (Japan), Medtronic Plc (Ireland), B. Braun Melsungen AG (Germany), Johnson & Johnson Services Inc. (US), Cook Group (US), CONMED Corporation (US), and XCELLANCE Medical Technologies (India).

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