Tuesday, 20 July 2021

Desmoid Tumors Market – Insights on Emerging Scope 2027

 Desmoid tumors are also known as desmoid fibromatosis. These benign growths occur very rarely in the general population. Desmoid tumor usually develops in the fibrous tissue of the body, commonly in the arms, legs or midsection, and sometimes in the head and neck. The term desmoid was derived from the Greek word desmos, which means tendonlike. Desmoid tumors appear as well-differentiated, and firm overgrowths of fibrous tissue. According to the U.S National Library of Medicine, Desmoid tumors are very rare as the rate of occurrence is estimated to be 1 to 2 per 500,000 people worldwide. It is also stated that nearly 900 to 1,500 new cases are registered per year in the United States. Tumors associated with familial adenomatous polyposis (FAP) are less common than sporadic desmoid tumors.

On molecular level, desmoid tumor is characterized by one of the two mutations in the gene i.e. mutations in the adenomatous polyposis coli (APC) gene, or in the β-catenin gene, CTNNB1. During diagnostic procedures CTNNB1 mutation is detected, especially, when pathological differential diagnosis is difficult.

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Rising demand of effective chemotherapeutic agents, high unmet needs of current treatment, and increase in research and development expenditure will promote the growth of desmoid tumors market. According to the Desmoid Rare Foundation, individuals within the age group of 15 and 60 are more likely to get affected. It is also stated that the condition is more prevalent in women than in men (2:1).

High cost of treatment & management of desmoid tumors and related disorders, and lack of infrastructure in middle and low income countries may hamper the growth of the market.

It is estimated that desmoid tumors market is expected to grow at a CAGR 4.5% during the forecast period of 2017-2023.

Regional Analysis

The Americas dominate the desmoid tumors market owing to the rising awareness among people, and increasing healthcare expenditure. As per the facts suggested by Centers for Disease Control and Prevention (CDC), it is found that out of total annual healthcare expenditure, 86% is for people with chronic health conditions in the United States. Furthermore, increasing participation of bigger players and new marketers towards advancement in treatment approaches have also attracted a great deal of attention.

Europe holds the second position in the desmoid tumors market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the market in Europe region.

Asia Pacific is the fastest growing desmoid tumors market owing to the huge patient pool and developing healthcare technology.

The Middle East & Africa has the lowest market for desmoid tumors market due to lack of technical knowledge and poor medical facilities.

Segmentation

The desmoid tumors market is segmented on the basis of diagnosis, treatment, and end-user.

On the basis of diagnosis, market is segmented into biopsy, electron microscopic examination, immunohistochemical analysis, others

On the basis of treatment, market is classified into surgery, radiation therapy, anti-inflammatory medication, hormone therapy, chemotherapy, novel molecular-targeted therapy, others. Novel molecular-targeted therapy is further segmented into gleevec based therapy, and sorafenib based therapy

On the basis of end-user, market is segmented into hospital, clinics, and others. 

Key Players

Some of key the players in the market are Amgen Inc., Novartis AG, Abbott Laboratories, Bayer AG, AbbVie Inc., Beckman Coulter Inc., Stryker Corporation, Debiopharm Group, F. Hoffmann-La Roche Ltd, and others.

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Lung Function Tests Market: Opportunities and Forecast Assessment, 2020-2027

 Lung function tests, also known as pulmonary function test is used for the diagnosis of lung disorders such as asthma, respiratory infections, chronic obstructive pulmonary disease (COPD), and others. These group of tests also determine the functioning of the lungs, and the ability of a person to breath. They are also a part of tests for routine examination by the healthcare provider. The healthcare provider may recommend lung function tests to diagnose the suspected lung disease, plan the treatment, and decide whether to continue the ongoing treatment or change it and even to stop the treatment if required. Therefore, lung function test plays a vital role in the diagnosis of various respiratory diseases, and lung disorders.

Rising prevalence of lung diseases such as asthma, COPD, and others, availability of lung function test devices, and increasing demand for lung function tests are important factors accelerating the growth of the market. Technological advancements in lung testing and the growing geriatric population are also influencing the market growth. Changing lifestyle, and smoking addiction are leading to a number of lung problems such as lung cancer, which is further driving the growth of the market.

The global lung function tests market is expected to grow at a CAGR of 5.7% during the forecast period.

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Major Players in Lung Function Tests Market:

Some of the key players in the global market are CareFusion Corporation (U.S.), MGC Diagnostic Corporation (U.S.), General Electric Company (U.S.), Perkin Elmer (U.S., Carestream Health, Inc. (U.S.), COSMED srl (Italy), NIHON KOHDEN CORPORATION (Japan), and others.

Regional Analysis

The lung function tests market is growing at a rapid pace in the Americas owing to emphasis on healthy lifestyle, and prevention of lung diseases. Also, increasing demand for technologically advanced diagnostic devices and the presence of major market players adding fuel to the growth of the market.

In Europe, the prevalence of allergic conditions is high, especially asthma, and allergy rhinitis. Rising prevalence of allergic conditions, and extensive research and development activities on the medical devices drive the market growth.

In Asia Pacific, the increasing prevalence of asthma, chronic obstructive pulmonary disease, poor healthcare system, and availability of diagnostic services leads the market growth. According to the data from GLOBOCAN, in 2012, the age-standardized rate (ASR) of incidence of gastrointestinal diseases in Asia Pacific was 15.8 and mortality was 11.7 per 100,000 person. According to World Health Organization (WHO), the geriatric population in China in the year 2013 was 22.6 million which is expected to show a massive growth to 90.4 million in 2050.

In the Middle East & Africa, the demand for medical devices is increasing for the diagnosis of chronic diseases such as COPD and others. Rising awareness about lung diseases among the adults, and development of the healthcare sector in the African countries also drive the growth of the market.

Segmentation

The global lung function tests market is segmented on the basis of type, indication, devices, and end user.

On the basis of the type, the market is segmented into spirometry, gas diffusion test, body plethysmograph, bronchial provocation test, and others.

On the basis of the indication, the market is segmented into asthma, chronic bronchitis, respiratory infections, chronic obstructive pulmonary disease, cystic fibrosis, pneumonia, lung cancer, and others.

On the basis of the devices, the market is segmented into spirometer, breath CO monitor, oscillometer, ergospirometer, dose controlled drug nebulizer, and others.

On the basis of the end user, the market is segmented into hospitals, clinics, diagnostic centers, and others.

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Achondrogenesis Market Detailed Industry Report Analysis 2020-2027

 Achondrogenesis is a severe congential growth hormone deficiency that affects cartilage and bone development. This rare genetic disease is characterized by narrow chest, rounded abdomen, and extremely short limbs. There are majorly three types of achondrogenesis, type 1A, type 1B and type 2. Out of these three, type 1B is most severe and caused by mutations in the SLC26A2 gene. Achondrogenesis type 1B (ACG1B) is also known as Parenti-Fraccaro type. Achondrogenesis exhibits various symptoms such as, abdominal distention, flat face, anteverted nares, frontal bossing, lethal skeletal dysplasia, hydropsfetalis, abnormal enchondral ossification, and many others. According to the U.S National Library of Medicine, the incidence of 1A and 1B, whereas achondrogenesis type 2 occur in 1 in 40,000 to 60,000 newborns. The condition of achondrogenesis type 2 is mostly found in combination with hypochondrogenesis.

Appropriate treatment for the condition is unknown but to deal with the symptoms associated with achondrogenesis, palliative care is suggested by physicians. Genetic Counseling is also recommended to the people who have genetic disorders in their family history. Diagnosis or testing of achondrogenesis is based on histopathologic, clinical, and radiologic features. As per an article published in GeneReviews book, it is found that SLC26A2 is the only mutated gene known to cause ACG1B. Out of all the testing methods, molecular genetic testing is the most commonly used diagnosis for Achondrogenesis Type 1B. Molecular genetic testing method includes targeted mutation analysis, sequence analysis, and deletion/duplication analysis.

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It is estimated that achondrogenesis market is expected to grow at a CAGR 3.9% during the forecast period of 2017-2023. 

Regional Analysis

The Americas dominate the achondrogenesis market owing to the rise in awareness among people, and high healthcare expenditure. According to the Centers for Disease Control and Prevention, in 2015, the total health expenditure in the United States was reported as USD 3.2 trillion and hospital care accounted for a share of 32.3%.

Europe holds the second position in achondrogenesis market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the market in Europe region.

Asia Pacific is the fastest growing achondrogenesis market owing to the huge patient pool and developing healthcare technology.  

Segmentation

The achondrogenesis market is segmented on the basis of type, diagnosis, and end-users.

On the basis of type, market is segmented into surgery achondrogenesis type IA (Houston-Harris type), achondrogenesis type IA (Houston-Harris type), and achondrogenesis type II (Langer-Saldino type).

On the basis of diagnosis, market is classified into physical examination, molecular genetic testing, and biochemical testing. Physical examination is further classified into X-ray, ultrasound, and others. Molecular genetic testing is also further segmented into Chorionic Villus Sampling (CVS), aminocentesis, and others.

On the basis of end-users, market is segmented into hospital & clinics, diagnostic centers, research & academic institutes, and others.

Key Players

Some of key the players in the achondrogenesis market are Cook, Thermo Fisher Scientific, CooperSurgical Inc., Illumina, Inc., Siemens AG, FUJIFILM Holdings Corporation, Koninklijke, Philips N.V., Stryker, Toshiba Corporation, Invivoscribe, Abbott Molecular Inc., INVITROGEN CORPORATION, Roche Molecular Systems, Inc., and others.

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Corneal Transplant Market Foraying into Emerging Economies 2020-2027

 Corneal transplant is a procedure to replace the damaged or diseased cornea which may be due to eye injury or eye disease. Two major types of corneal transplants are penetrating keratoplasty (full thickness cornea transplant) and endothelial keratoplasty (back layer cornea transplant). Need for corneal transplant may rise if the diseased cornea leads to blurred vision.  According to the World Health Organization (WHO), 285 million people are estimated to be visually impaired worldwide.

The market for corneal transplant shows exponential growth due to high prevalence of corneal eye disease and rising number of corneal transplants in developed countries. High cost of corneal transplants may restrain the market growth. For instance, the cost of corneal transplant is higher in U.S. than other countries in the Asia Pacific.

The global corneal transplant market size is expected to grow at a CAGR of 8.5% during the forecast period 2017 to 2023.

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Major Players in Corneal Transplant Market:

Some of the key players in the global market are CryoLife, Inc. (U.S.), Exactech, Inc. (U.S.), Köhler GmbH (U.S.), Lifeline Scientific (U.S), LifeCell Corporation (U.S.), Medtronic (U.S.), and Organogenesis Inc. (U.S.).

Regional Analysis

Europe is the largest market for corneal transplant which will exhibit positive growth in the near future due to rising prevalence of diabetes in the European countries and availability of treatment options. According to the World Health Organization, about 60 million Europeans have diabetes and its prevalence is relatively high among people over 25 years.

America is the second leading corneal transplant market across the globe owing to an increasing demand for corneal transplant surgery, and rising prevalence of eye diseases, and vision impairment among people in the U.S.

Asia Pacific market is expected to grow rapidly owing increasing prevalence of chronic diseases such as diabetes, diabetic retinopathy, and obesity. India is one of the international medical tourism destinations across the world, which further exhibits growth opportunities for the corneal transplant market due to availability of cost-effective treatment and rising success rates. Furthermore, the increasing healthcare expenditure by developing countries in Asia Pacific region also contributes to the market growth.

The Middle East & African market is growing steadily owing to rising demand for ophthalmic products and services, and available treatment options.

Segmentation

The global corneal transplant market is segmented on the basis of type, indication, and end user.

On the basis of type, the market is segmented into penetrating keratoplasty, endothelial keratoplasty, descemet stripping automated endothelial keratoplasty (DSAEK), corneal graft, corneal limbal stem cell transplant, and others.

On the basis of indication, the market is segmented into fungal corneal ulcer, bullous keratopathy, keratoconus, keratitis, corneal stromal dystrophies, and others.

On the basis of end user, the market is segmented into hospitals, eye clinics, and others.

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Inguinal Hernia Market – Insights on Emerging Scope 2027

 Inguinal hernia results when a part of small intestine bulges out through a weak area in the lower abdominal wall. Two types of inguinal hernia are known- direct and indirect inguinal hernia.  Direct inguinal hernia occurs in males resulting into the weakening of the abdominal muscles around the inguinal canal. Whereas, indirect inguinal hernia is caused by the defects in the abdominal wall present at the birth. The prevalence of inguinal hernia is found to high in males, which is attributed to stress and increasing age. 

The market for inguinal hernia is expected to show a healthy growth owing to increasing cases of hernia repair and increasing adoption of laparoscopic techniques across the globe. Furthermore, increasing number of hernia repair surgeries also contributes to the progress of the market. Therefore, demand for hernia repair devices is found to be increasing. On the other hand, High cost of the hernia repair devices may act as a restrain for the market growth.

The global inguinal hernia market is expected to grow at a CAGR of 10.8% during the forecast period.

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Major Players in Inguinal hernia Market

Some of the key players in the global market are Ethicon, Inc. (U.S.), Medtronic (U.S.), C.R. Bard, Inc. (U.S.), Atrium (U.S.), W.L. Gore & Associates Inc. (U.S.), Acelity (U.S.), and B Braun Melsungen AG (Germany).

Regional Analysis

America is the largest market for inguinal hernia owing to rising prevalence in the U.S. and increasing surgical procedures cases such as groin hernia repair.

Europe is the second largest market owing to increasing prevalence of inguinal hernia and extensive demand for hernia repair devices. The U.K is expected to be the largest market in Europe over the review period.  According to the New England Journal of Medicine, in 2014 more than 90,000 surgical intervention for inguinal hernia were performed in Europe.

In Asia Pacific, rising demand for laparoscopic procedures for inguinal hernia. India is expected to be the largest market in Asia Pacific followed by China and Japan.

The Middle East & Africa also shows a steady rise in the market owing to extensive use of hernia mesh devices for surgeries in the Middle East. In the Middle East, Iran is expected to be the largest market followed by Saudi Arabia. In Africa, high cost of hernia repair restrained the market growth.

Segmentation

The global inguinal hernia market is segmented on the basis of type, diagnosis, treatment and hernia mesh devices.

On the basis of types, market is segmented into direct and indirect hernia. 

On the basis of diagnosis, the market is segmented into physical examination and imaging test. Imaging tests is further segmented into abdominal ultrasound, CT scan and Magnetic Resonance Imaging (MRI).

On the basis of treatment, the market is segmented into open hernia repair, laparoscopy, and others.

On the basis of hernia mesh devices, the market is segmented into synthetic mesh, and biologic mesh.

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Serotonin Syndrome Market Foraying into Emerging Economies 2020-2027

 Serotonin syndrome is a group of symptoms such as high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, diarrhoea etc. due to use of serotonergic drugs. Serious complications such as seizures and extensive muscle breakdown may occur which may lead to death. The 1984, Libby Zion case is an example of death from serotonin syndrome. Serotonin syndrome is typically caused by synergistic effect of two or more serotonergic drugs which generally include selective serotonin reuptake inhibitor (SSRI), serotonin norepinephrine reuptake inhibitor (SNRI), monoamine oxidase inhibitor (MAOI), tricyclic antidepressants (TCAs), amphetamines etc. Other drugs with a high propensity of causing serotonin syndrome are dextromethorphan, buspirone, L-tryptophan, St. John's wort, metoclopramide, ondansetron etc. There is no laboratory test to confirm the diagnosis of serotonin syndrome.

The treatment for serotonin syndrome consists of discontinuing medications contributing to the condition. For serious cases, other treatments for managing associated symptoms may be used. For serious cases with a threat to life gastrointestinal decontamination using activated charcoal is performed. Sedatives such as benzodiazepines are used for agitated patients. High fever is a common symptom of serotonin syndrome which reaches extremely high temperatures greater than forty centigrade. To control hyperthermia cooling measures may be needed. Serotonin antagonist such as cyproheptadine may be needed.

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The serotonin syndrome market restraints are the low number of cases and equally low number of fatalities associated with the syndrome with less than 1% cases consuming serotonin syndrome causing drugs developing the diseases. Mild symptoms occur in about 15% of SSRI overdoses.

Considering all these factors, the serotonin syndrome market is expected to reach $ 400 million by the end of 2023, this market is projected to growing at a CAGR of ~ 2.3 % during 2017-2023.

Segments:

The global serotonin syndrome market is segmented on the basis of drug treatment, and end users. Based on drug treatment, the market has been segmented as serotonin antagonists, supportive care (Muscle relaxants, the control of autonomic instability, anti-hyperthermics, antihypertensive and others. Based on the end users, the market has been segmented as hospitals, point of care and others.

Regional analysis
US accounts for the maximum market share due to greater use of medications and greater expenditure on healthcare. The faster market uptake of new technology and devices in the US is also an important driver of the market for
 global serotonin syndrome diagnosis and treatment. Europe is the second largest market due to large disposable income and rising awareness. Asia Pacific region is expected to have the most future potential and it is estimated to be led by China and India. The Middle East & Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The regions of Africa are expected to witness a moderate growth due to poor economic and political conditions and poor healthcare penetration.

Key players of Global Serotonin syndrome market:
Key players profiled in the report are AstraZeneca Plc., Eli Lilly and Company, Forest Laboratories Inc., GlaxoSmithKline plc., Johnson & Johnson, Merck & Co., Inc., Pfizer, Inc. and Sanofi S.A., Ciron Drugs & Pharmaceuticals Pvt. Ltd. and others. The report for Global Serotonin syndrome market by Market Research Future comprises of extensive primary research along with the detailed analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of the current market scenario which includes past and estimated future market size with respect to value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information about and strategies used by top key players in the industry. The report also gives a broad study of the different market segments and regions.

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Cystectomy Market Detailed Industry Report Analysis 2020-2027

 Cystectomy is the surgical removal of all or part of the urinary bladder or the removal of a cyst, or the gallbladder.

The market for cystectomy is driven by factors such as growing prevalence of cysts, rupture of bladder due to trauma etc. However, the rise of bladder cancer is the strongest driver of the market. The market constraints are risk of infection which may lead to inflammation of the abdomen membrane. In case of partial cystectomy, there is a risk of urine leakage from the bladder incision site. Other risks include complications and pain associated with cystectomy and cancer recurrence after cystectomy.

Considering all these factors, the cystectomy market is expected to reach USD 1.2 billion by the end of 2023, this market is projected to growing at a CAGR of ~ 5.5 % during 2017-2023.

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The global cystectomy market is segmented on the basis of cystectomy types, methodology and end users. Based on cystectomy types, the market has been segmented as partial cystectomy, simple cystectomy and radical cystectomy. Based on the methodology, the market has been segmented as open surgery, minimally invasive surgery and robotic surgery Based on the equipment, the market has been segmented as general surgical instruments, diagnostic instruments, surgical robots and others. Based on the end users, the market has been segmented as hospitals and clinics, urology centers and others.

Regional analysis

US accounts for the maximum market share due to favorable reimbursement scenario and greater expenditure on healthcare. The faster market uptake of new technology in the US is also an important driver of the market for global cystectomy. Europe is the second largest market due to large disposable income and rising awareness. Asia Pacific region is expected to have the most future potential and it is estimated to be led by China and India. The Middle East & Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The regions of Africa are expected to witness a moderate growth due to poor economic and political conditions and poor healthcare penetration.

Key players of Global Cystectomy Market:

Key players profiled in the report are Zephyr Surgical Implants, Intuitive Surgical Inc., Advanced Health Care Resources, Millennium Surgical Corp., Richard Wolf Medical Instruments, Boston Scientific Corporation, Titan Medical Inc., Verb Surgical, TransEnterix and others. The report for Global Cystectomy Market by Market Research Future comprises of extensive primary research along with the detailed analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of the current market scenario which includes past and estimated future market size with respect to value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information about and strategies used by top key players in the industry. The report also gives a broad study of the different market segments and regions.

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