Global Orphan diseases Market Industry Production and Demand, Competition News and Trends Forecasts to 2027

 The global orphan drugs market is expected to exhibit a robust 11.5% CAGR over the forecast period from 2018 to 2023, according to the latest research report from Market Research Future (MRFR). The global orphan drugs market is mainly driven by the growing research into rare diseases and the growing government support to research and development into making orphan drugs. The global orphan drugs market is profiled in great detail in the research report, providing readers with a comprehensive overview of the market through its historical growth trajectory, present conditions, and future growth prospects. The historical stats of the orphan drugs market are detailed in the report, in order to provide readers with a complete overview of the market’s historical growth trajectory. The historical stats provided in the report also give analysts a solid platform to base future projections about the market. Based on this platform, future projections for the orphan drugs market’s growth trajectory over the forecast period are provided in the report. The leading players in the global orphan drugs market are also profiled in the report in order to give readers a comprehensive analysis of the leading players in the global orphan drugs market. The major drivers and restraints affecting the global orphan drugs market are also profiled in the report to provide readers a comprehensive overview of what’s making the market tick and what is holding the market back.

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Orphan drugs are drugs made to counter rare diseases. The name orphan drugs comes from the fact that many drug makers have no interest in producing these drugs, due to the rarity of the diseases they treat. However, increasing government incentives to produce orphan drugs and the growing prevalence of rare diseases are likely to be major drivers for the global orphan drugs market. Increasing awareness about rare diseases is likely to be a major driver for the global orphan drugs market over the forecast period. On the other hand, high treatment costs and the regulatory restrictions on profitability from orphan drugs are likely to be the major restraints against the market.

Orphan Drugs Market Competitive Leaderboard:

Leading players in the global orphan drugs market include Bristol Myers Squibb, Pfizer Inc., Vertex Pharmaceuticals Inc., Alexion Pharmaceuticals Inc., Janssen Global Services LLC, Sanofi, Shire Pharmaceutical, Eli Lilly and Company, Merck KGaA, Takeda Pharmaceutical Company Ltd., Biogen, Novartis AG, Celgene Corporation, Mylan, and F. Hoffman-La Roche AG.

In December 2018, Merck announced that its treatment for biliary tract cancer has received orphan drug designation from the European Medicines Agency (EMA).

Orphan Drugs Market Segmentation:

The global orphan drugs market is segmented on the basis of drug type, sale, drug, therapy class, and region.

By drug type, the global orphan drugs market is segmented into biologics and non-biologics. The biologics segment holds the largest share in the global orphan drugs market. The segment accounted for USD 75,103.32 million in 2017.

By sale, the global orphan drugs market is segmented into generic and prescribed.

By drug, the global orphan drugs market is segmented into Revlimid, Rituxan, Opdivo, Keytruda, Imbruvica, Soliris, Jakaf, Pomalyst, Darzalex, Spinraza, and Adcetris.

By therapy class, the global orphan drugs market is segmented into oncology, hematology, central nervous system, endocrine, cardiovascular, and respiratory.

Orphan Drugs Market Regional Analysis:

The Americas hold the dominant share in the global orphan drugs market. The region accounted for close to 40% of the global orphan drugs market in 2017. The increasing prevalence of rare diseases in North America and the growing awareness about the same is a major driver for the orphan drugs market in the region.

Europe holds the second largest share in the global orphan drugs market and is likely to rise strongly in the coming years due to the growing government support to the development of orphan drugs in the region. The increasing number of companies operating in the orphan drugs market in Europe is likely to be a major driver for the global orphan drugs market.

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Research report explores the Point of Care Blood Gas and Electrolyte Market for the forecast period, 2020-2027

 Point of care blood gas and electrolyte analyzers is the new technology, which helps in reducing therapeutic turnaround time, enhancing patient satisfaction, accuracy, and help to improve hospital operations. Rising prevalence of chronic diseases and cancer across the globe, increasing the treatment of NICUs, ICUs, Cardiovascular Operating Room (CVOR), and emergency department, which drives the global point of care blood gas and electrolyte devices market growth. In 2017, due to changes in the regulatory policies of the U.S., R&D investment is affected to some extent. In 2016, R&D spending of the US was 527.5 billion, which grew by 1.6% in 2017. Currently, the major shares of the global market are dominated by few leading players, and they can fluctuate the costs of the products. In developing regions such as Asia Pacific the suppliers are trying to provide their products at affordable price.

The global point of care blood gas and electrolyte devices market is expected to grow at a CAGR of 7.8% during the forecast period 2017-2023. 

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Segmentation

The global point of care blood gas and electrolyte gas devices market has been segmented on the basis of types and end users.

On the basis of the types, the market is segmented into consumables and Instruments. The instrument type is sub-segmented into benchtop and portable devices. The consumable devices are further segmented into reagents, cartridges, and others.

On the basis of the end users, the market is segmented into hospitals & clinics, home care, research institutions, and others. 

Regional Analysis

The Americas dominate the global market owing to a huge population with chronic diseases such as diabetes, kidney, and liver disease, increasing government support for research & development, and high health care expenditure. According to the WHO, in 2014, 9.7% of the total America population is having diabetes. Thus, increasing prevalence of diabetes has boosted the market growth. Additionally, changing lifestyle and the presence of major players in the market have fuelled the growth of the market.

Europe is the second largest point of care devices market across the globe, which is followed by Asia Pacific. Asia Pacific is the fastest growing market and majorly driven by India and China owing to a huge number patients with chronic diseases and rapidly growing economy. According to the WHO, 60% of the global diabetic population lives in Asia Pacific region. The healthcare expenditure of Asia Pacific has increased over the last few years, which has contributed to the growth of the market.

The Middle East and Africa region account for the least share of the global market. Whereas, Africa holds the least share of the global market due to limited availability of medical facilities and poor economic condition of the region. 

Key Players

Some of the major players in this market: Siemens, Abbott, F. Hoffman-La Roche Ltd., Radiometer, Nova medical, Edan Instruments Inc., and Instrumentation Laboratory

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Impact of Existing and Emerging Global Jaw Surgery Market Trends And Forecast 2020-2027

 Jaw Surgery is performed to correct various problems related to the jaw, facial appearance, and other maxillofacial problems. Maxillary and/or mandibular facial skeletal deformities, speech impairment, chronic jaw or jaw joint pain, and facial trauma are various indications for which the oral and maxillofacial surgeons recommend jaw surgery. The procedure is found to show good results thus improving facial appearance among a number of patients across the globe.

There is a rise in the demand for jaw surgery across the globe, especially in the developing countries.  The market is driven by the rising demand for maxillofacial procedure and availability of treatment at an affordable cost. In addition, increasing research and development activities, and technological advancements in the field for orthognathics and orthodontics fuelling the global market growth. Additionally, rising awareness about the use of new devices of orthognathic surgery among the oral and maxillofacial surgeons also determine the progress of the market. Availability of affordable treatment in the developed as well as developing regions across the globe also fuels the growth of the market.

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The entry of new players is restricted by fierce competition among the existing players offering wide range of devices and instruments for jaw surgery.

The global jaw surgery market is expected to grow at a CAGR of 3.7% during the forecast period.

Taste the market data and market information presented through more than 55 market data tables and figures spread over 101 pages of the project report. Avail the in-depth table of content (TOC) & market synopsis on “Jaw Surgery market research report–Global forecast till 2023.”

Major Players in the Market:

Some of the key players in the global market are Integra LifeSciences Corporation (U.S.), The Amato Centers for Facial Surgery (U.S.), The Restful Jaw Company, LLC. (U.S.), Millennium Surgical Corp (U.S.), Scanlan International. (U.S.),  Novo Surgical Inc. (U.S.),  HAAG-STREIT GROUP (U.S.), Eurosurgical (U.K),  Sklar Surgical Instruments (U.S.), and others.

Regional Analysis

The market is found to be increasing in the Americas. Increasing number of surgical procedures, and increasing demand for technologically advanced devices for orthognathic procedures are the major drivers for the growth of the market in the U.S. and Canada. Further, concentration of key players manufacturing surgical instruments also fuels the growth of the market.

In Europe, extensive use of technological advanced technologies such as 3D printing for jaw surgeries, and increasing financial support from the government for research and development activities drive the growth of the market. Additionally, increasing number of surgical instrument manufacturers for orthognathic surgery also accelerate the development of the market.

In Asia Pacific, the increasing number of maxillofacial procedures, and rising demand for new technologies also fuel the growth of the market. Additionally, changing lifestyle, and availability of skilled healthcare professionals such as oral and maxillofacial surgeon also marks the development of orthognathic procedures in Asia Pacific. Furthermore, rising awareness about jaw discrepancies and their treatment is also responsible for the growth of the market.

In the Middle East & Africa, rising awareness about orthognathic and orthodontic surgery of treatment of functional deformities related to jaw, teeth, and others. The Middle East acquires the largest market share owing to the availability of specialty healthcare services in the regions such as the United Arab Emirates, and Saudi Arabia. The market shows steady growth in Africa owing to low technological penetration, and increasing demand for primary care services.

Segmentation

The global market is segmented on the basis of instruments, indication, and end user.

On the basis of instruments, market is segmented into curettes, elevators, forceps and needle holders, retractors and speculums, and others.

On the basis of indication, the market is segmented into maxillary and/or mandibular facial skeletal deformities, speech impairments, chronic jaw or jaw joint pain, facial trauma, and others.

On the basis of end user, the market is segmented into hospitals, clinics, and others.

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Global Arteriovenous malformation Market size and forecast, 2020-2027

 Increasing prevalence of neurological/brain disorder like arteriovenous malformation, epilepsy, rising need for better treatment for rare disease, increasing investment of biotechnology and pharmaceutical industries in R&D, and availability of funds drive the growth of the market. Moreover, increasing government support for research & development, changing lifestyle, and rapid development in technology will fuel the market growth during the forecast period. On the other hand, higher cost of the treatment procedure may slow the market growth during the review period.

Over the last decade, the number of hospitals has increased to a great extent, which has influenced the growth of the market positively. Moreover, increasing demand for better treatment and changing reimbursement policies have fueled the market growth.

The global arteriovenous malformation market is expected to grow at a CAGR of ~6.1% during the forecast period 2017-2023.

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Regional Analysis

The Americas dominate the global arteriovenous malformation market owing to the presence of huge patient population, high health care spending, and increasing government support for research & development.     

Europe holds the second largest share of the global market. The increasing focus of various government agencies on treating various brain disorders or brain injuries such as epilepsy and depression will have a positive impact on the growth of the market. The growing public awareness will boost the adoption of these devices in the European market.  

Asia Pacific is the fastest growing arteriovenous malformation market across the globe. Japan holds a major share of the regional market due to availability of technology and huge healthcare spending. Rapidly developing economy, increasing healthcare expenditure, and government initiatives for research & development will drive the market in China and India over the assessment period.      

The Middle East and Africa hold the least share of the global market due to limited availability of medical facilities. The UAE, Saudi Arabia, and Kuwait are expected to drive the Middle East & African market whereas, the African region is expected to witness a moderate growth.  

Segmentation

The global arteriovenous malformation market is segmented on the basis of types, diagnosis, treatment, and end user. On the basis of types, it is segmented into true arteriovenous malformation, occult or cryptic AVM or cavernous malformations, venous malformation, hemangioma, and dural fistula. On the basis of diagnosis, it is segmented into physical examination, blood test, brain scans, and others. Brain scan is further segmented into computerized tomography (CT) scan, Magnetic Resonance Imaging (MRI), magnetic resonance angiography (MRA), and electroencephalography (EEG). On the basis of treatment, the market is segmented into endovascular embolization, neurosurgery and others. On the basis of the end user, it is segmented into hospitals & clinics, research laboratories and others.

Key Players

Some of key the players in the market are Toshiba Medical Systems Corporation (Japan), Carestream Health (U.S.), Nihon Kohden Corporation (Japan), Electrical Geodesics Inc. (U.S.), Fujifilm Holdings (Japan), GE Healthcare (U.S.), Siemens Healthcare(U.S.), Philips Healthcare (U.S.), Shimadzu Corporation (Japan), Masimo Corporation (U.S.), Hologic (U.S.), Esaote (Italy), and others.

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Desmoid Tumors Market Growth, Trends and Value Chain 2020-2027

 Desmoid tumors are the benign fibrous growths which usually develops in the fibrous tissue of the body, commonly in the arms, legs or midsection, and sometimes in the head and neck. According to the U.S National Library of Medicine, Desmoid tumors are very rare as the rate of occurrence is estimated to be 1 to 2 per 500,000 people worldwide. It is also stated that nearly 900 to 1,500 new cases are registered per year in the United States. Tumors associated with familial adenomatous polyposis (FAP) are less common than sporadic desmoid tumors. On the molecular level, desmoid tumor is characterized by one of the two mutations in the gene i.e. mutations in the adenomatous polyposis coli (APC) gene, or in the β-catenin gene, CTNNB1. During diagnostic procedures CTNNB1 mutation is detected, especially, when pathological differential diagnosis is difficult. The symptoms of desmoid tumors include a painless swelling or lump, pain and obstruction of the bowels, limping, pain caused by compressed nerves or muscles, and others. For the diagnosis of desmoid tumor there are many non-invasive methods available to detect desmoid tumor which include ultrasound, MRI scan, and CT scan. The actual diagnosis of this tumor can be made only after examining a small piece of the tumor by a trained pathologist.

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Rising demand of effective chemotherapeutic agents, high unmet needs of current treatment, and increase in research and development expenditure will promote the growth of desmoid tumors market. According to the Desmoid Rare Foundation, individuals within the age group of 15 and 60 are more likely to get affected. It is also stated that the condition is more prevalent in women than in men (2:1).

High cost of treatment & management of desmoid tumors and related disorders, and lack of infrastructure in middle and low income countries may hamper the growth of the market.

It is estimated that desmoid tumors market is expected to grow at a CAGR 4.5% during the forecast period of 2017-2023.

Regional Analysis

The Americas dominate the desmoid tumors market owing to the rising awareness among people, and increasing healthcare expenditure. As per the facts suggested by Centers for Disease Control and Prevention (CDC), it is found that out of total annual healthcare expenditure, 86% is for people with chronic health conditions in the United States. Furthermore, increasing participation of bigger players and new marketers towards advancement in treatment approaches have also attracted a great deal of attention.

Europe holds the second position in the desmoid tumors market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the market in Europe region.

Asia Pacific is the fastest growing desmoid tumors market owing to the huge patient pool and developing healthcare technology.

The Middle East & Africa has the lowest market for desmoid tumors market due to lack of technical knowledge and poor medical facilities.

Segmentation

The desmoid tumors market is segmented on the basis of diagnosis, treatment, and end-user.

On the basis of diagnosis, market is segmented into biopsy, electron microscopic examination, immunohistochemical analysis, others

On the basis of treatment, market is classified into surgery, radiation therapy, anti-inflammatory medication, hormone therapy, chemotherapy, novel molecular-targeted therapy, others. Novel molecular-targeted therapy is further segmented into gleevec based therapy, and sorafenib based therapy

On the basis of end-user, market is segmented into hospital, clinics, and others. 

Key Players

Some of key the players in the market are Amgen Inc., Novartis AG, Abbott Laboratories, Bayer AG, AbbVie Inc., Beckman Coulter Inc., Stryker Corporation, Debiopharm Group, F. Hoffmann-La Roche Ltd, and others.

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Lung Function Tests Market Growth, Trends and Value Chain 2020-2027

 Lung function tests are a part of routine diagnostic tests recommended by the healthcare provider. These tests are used to diagnose number of respiratory diseases such as chronic obstructive pulmonary disease (COPD), and allergic conditions such as asthma. It comprises of tests such as spirometry, gas diffusion test, body plethysmography, bronchial provocation test, and others. Lung function tests also determine the whether the lungs are working properly, and their capacity to carry out respiration, thus making it necessary to identify the mode of treatment, and administration of drugs.

Prevalence of asthma is on the rise across the globe, especially in the developing countries.  The market is driven by the increasing prevalence of respiratory diseases in urban areas for developing countries, and rising geriatric population. Additionally, increasing research and development activities, and technological advancements to identify the causes and risk factors for infectious lung diseases are fuelling the global lung function tests market growth.

The global lung function tests market is expected to grow at a CAGR of 5.7% during the forecast period.

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Major Players in Lung Function Tests Market:

Some of the key players in the global market are CareFusion Corporation (U.S.), MGC Diagnostic Corporation (U.S.), General Electric Company (U.S.), Perkin Elmer (U.S., Carestream Health, Inc. (U.S.), COSMED srl (Italy), NIHON KOHDEN CORPORATION (Japan), and others.

Regional Analysis

The lung function tests market is growing at a rapid pace in the Americas owing to emphasis on healthy lifestyle, and prevention of lung diseases. Also, increasing demand for technologically advanced diagnostic devices and the presence of major market players adding fuel to the growth of the market.

In Europe, the prevalence of allergic conditions is high, especially asthma, and allergy rhinitis. Rising prevalence of allergic conditions, and extensive research and development activities on the medical devices drive the market growth.

In Asia Pacific, the increasing prevalence of asthma, chronic obstructive pulmonary disease, poor healthcare system, and availability of diagnostic services leads the market growth. According to the data from GLOBOCAN, in 2012, the age-standardized rate (ASR) of incidence of gastrointestinal diseases in Asia Pacific was 15.8 and mortality was 11.7 per 100,000 person. According to World Health Organization (WHO), the geriatric population in China in the year 2013 was 22.6 million which is expected to show a massive growth to 90.4 million in 2050.

In the Middle East & Africa, the demand for medical devices is increasing for the diagnosis of chronic diseases such as COPD and others. Rising awareness about lung diseases among the adults, and development of the healthcare sector in the African countries also drive the growth of the market.

Segmentation

The global lung function tests market is segmented on the basis of type, indication, devices, and end user.

On the basis of the type, the market is segmented into spirometry, gas diffusion test, body plethysmograph, bronchial provocation test, and others.

On the basis of the indication, the market is segmented into asthma, chronic bronchitis, respiratory infections, chronic obstructive pulmonary disease, cystic fibrosis, pneumonia, lung cancer, and others.

On the basis of the devices, the market is segmented into spirometer, breath CO monitor, oscillometer, ergospirometer, dose controlled drug nebulizer, and others.

On the basis of the end user, the market is segmented into hospitals, clinics, diagnostic centers, and others.

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Impact of Existing and Emerging Global Dysfunctional Uterine Bleeding Market Trends And Forecast 2020-2027

 According to the American Society for Reproductive Medicine, dysfunctional uterine bleeding is most common during puberty and menopause. It can also can occur at any time in women due to hormonal imbalance. Polycystic ovary syndrome (PCOS), endometriosis, uterine polyps, uterine fibroids, Sexually Transmitted Diseases (STDS) are common causes of dysfunctional uterine bleeding. It can be diagnosed by performing an endometrial biopsy or blood tests.

The rising prevalence of uterine disorders such as endometrial cancer among women, availability of reliable diagnostic tests, and overall demand for new treatment for uterine bleeding drive the market growth.  Increasing number of awareness drives and campaigns regarding cancer among women further influence the market growth.

The global dysfunctional uterine bleeding market is expected to grow at a CAGR of 8.2% during the forecast period.

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Major Players in Dysfunctional uterine bleeding Market:

Some of the key players in the global market are B. Braun Melsungen AG (Germany), Hologic Inc. (U.S.), Karl Storz Gmbh & Co. KG (Germany), Medgyn Products, Inc., Olympus (Japan), Richard Wolf GmbH (Germany), Stryker (U.S.), Xion Medical GmbH (Germany), Cadila Pharmaceuticals Ltd. (India), Torrent Phamraceuticals (India).

Regional Analysis

America is the largest market for dysfunctional uterine bleeding market owing to the rising prevalence of uterine cancer and other uterine disorders among women. According to the American Cancer Institute, about 61,380 new cases of uterine cancer will be diagnosed in 2017 and 8% of the urine cancers are sarcomas.

Europe is the second largest market owing to an increasing demand for diagnosis and treatment measures for uterine cancer, fibroids and other disorder, and increasing emphasis on women healthcare. Additionally, availability of funds for research and development activities accelerates the market growth in the European countries.

The market in Asia Pacific is expected to grow at the fastest pace and is driven by the increasing prevalence of menstrual disorders, and sexually transmitted diseases (STI) among women in developing nations. Furthermore, increasing awareness about STI and preventive measures to be taken also influences the market growth.

The Middle East & Africa also show a steady rise in the market owing to increasing focus on women and child health, and need of primary care services in developing regions.

Segmentation

The global dysfunctional uterine bleeding market is segmented on the basis of type, diagnosis, treatment, and end user.

On the basis of type, market is segmented into ovulatory, and anovulatory.

On the basis of diagnosis, the market is segmented into hysteroscopy, ultrasonography, dilation and curettage, endometrial biopsy, and others.

On the basis of treatment, the market is segmented into pharmacologic treatment, hysterectomy, endometrial ablation, and others. The pharmacologic treatment includes oral contraceptives, estrogen, progestins, desmopressin and others.

On the basis of end user, the market is segmented into hospitals, clinics, diagnostic centers, pharmaceutical companies, and others.

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