Monday, 16 August 2021

Pharmacovigilance Market: Drivers, Restraints, Opportunities, and Threats (2020-2027)

 According to MRFR analysis, Pharmacovigilance Market is expected to register a CAGR of 14.1% during the forecast period of 2019 to 2025 and accounts for USD 4321.86 Million 2018.

Pharmacovigilance supports safe and appropriate use of drugs by identifying risk factors for the development of adverse drug reactions (ADR), promoting the detection of previously unknown ADR and their interactions with known ADR.

The market is dominated by numerous established players. The key players are involved in product launches and strategic collaborations to strengthen their market positions. For instance, on May 16, 2019, Accenture launched INTENT to improve the continuity and flow of data across life sciences enterprises, supporting the delivery of ground-breaking treatments for patients.

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Segmentation

The Global Pharmacovigilance Market has been segmented based on the clinical trial phase, service provider, type, and end-user.

The market, based on the clinical trial phase, has been divided into phase IV, phase III, phase II, phase I, and pre-clinical. Phase IV segment dominated the pharmacovigilance market as adverse drug reactions are majorly detected in this phase. Whereas, phase III is expected to witness the fastest growth.

The global pharmacovigilance market has been segmented, on the basis of service provider, into in-house and contract outsourcing. Contract outsourcing dominated the global pharmacovigilance market and expected to witness the fastest growth. Contract manufacturing serves multiple customers and thus can acquire raw materials at a reduced cost, benefiting from the economies of scale.  

The market, based on type, has been divided into spontaneous reporting, cohort event monitoring, intensified ADR reporting, targeted spontaneous reporting, and EHR mining. The spontaneous reporting held largest market share in 2018. Spontaneous reporting is a passive approach to pharmacovigilance as it entirely relies on the motivation of individuals to report suspected ADRs to a local or national pharmacovigilance center.

In terms of end-user, the global pharmacovigilance market has been segmented into hospitals, research organizations, pharmaceutical companies, and others. Hospitals take up the largest share due to an increase in the number of hospital admissions due to ADRs.

Key Players

Some of the key players in the Global Pharmacovigilance Market are Accenture (Ireland), ArisGlobal (US), BioClinica (US), Capgemini (France), Conquest Group BV (Netherlands), Cognizant (US), IBM Corporation (US), ICON PLC (Ireland), IMEDGlobal (US), ITClinical (Portugal), Laboratory Corporation of America Holdings (US), PAREXEL International Corporation (US), TAKE Solutions Ltd (India), United BioSource Corporation (US), and Wipro Ltd (India).

Regional Analysis

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas is expected to be the largest market owing to the high spending by the pharmaceutical industry. The pharmacovigilance market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada. The European Pharmacovigilance market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The Pharmacovigilance market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. Due to the increasing prevalence of chronic conditions and rising cases of ADRs and medication errors, the market in Asia-Pacific is expected to be the fastest-growing. The pharmacovigilance market in the Middle East & Africa has been divided into the Middle East and Africa.

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X-Linked Hypophosphatemia Market – Insights on Upcoming Trends 2027

 The Global X-linked Hypophosphatemia Market is estimated to be valued at USD 40,309.1 Thousand by 2025 and is expected to register a CAGR of 3.6% during the forecast period.

X-linked hypophosphatemia (XLH) is a rare genetic disorder caused by mutations in the phosphate regulating endopeptidase homolog (PHEX), X-Linked gene. XLH is also called as X-linked hypophosphatemic rickets, vitamin D-resistant rickets (VDRR), familial hypophosphatemic rickets, or genetic rickets.

The global X-linked hypophosphatemia market is mainly driven by factors such as rising cases of X-linked hypophosphatemia, increasing awareness about XLH and the severity of the disease, and the proactive initiatives for researching the field of XLH. However, the high cost of the drug and limited availability of treatment options may slow down the growth of the market in the future. On the other hand, a recent drug approval by regulatory authorities such as the US FDA, Health Canada, and the European Medical Agency is likely to offer lucrative opportunities for the growth of the market shortly.

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Segment Analysis

The X-linked hypophosphatemia (XLH) market by treatment has been segmented into medication and surgical or orthopedic treatment. According to a press release by the US FDA in April 2018, XLH affected approximately 3,000 children and 12,000 adults in the US alone. The increasing number of people suffering from phosphate deficiency is driving the X-Linked Hypophosphatemia market as this raises the demand for the treatment of this disease.

The X-linked hypophosphatemia market has been categorized by the end user into hospitals and clinics and research centers. The hospitals and clinics segment is expected to register a relatively good CAGR during the forecast period from 2019 to 2025. A regular rise in the number of private and government hospitals in developing countries such as India, China, and Indonesia with an increase in the number of diagnosis and treatment procedures for X-linked disorders is expected to support the profitable growth of this segment. According to the survey conducted by the American Hospital Association (AHA), the total number of hospitals in the US are 6,210. Also, the increase in the use of medication, corrective surgery, and dental procedure to cure XLH is supporting the growth of this segment.

Regional Analysis

The XLH market in the Americas is expected to hold a major market share owing to the growing prevalence of XLH in the US and Canada and the presence of a well-established healthcare sector. The rising research funding towards rare diseases such as XLH and the high healthcare expenditure is also expected to fuel the growth of the market during the forecast period. For instance, Genome Canada and the Canadian Institutes for Health Research entered into a partnership to study rare genetic diseases by using Next-Generation Sequencing (NGS) technology.

Followed by America, the European market is expected to be the second-largest X-linked hypophosphatemia market. The rising prevalence rates of XLH, technological advances, well-developed health care sector, and government support for the research and development have fueled the growth of the market.

Asia-Pacific is anticipated to be the fastest-growing market owing to the growing healthcare expenditure and the presence of a large patient pool. Growing investments by market players in the region due to the growing demand for the treatment of rare diseases is expected to contribute to the growth of the market.

Market Players

Market Research Future (MRFR) recognizes Ultragenyx Pharmaceutical (California), Validus Pharmaceuticals LLC (New Jersey), Prospec-Tany Technogene Ltd (Israel), Merck KGaA (Germany), Zeria Pharmaceutical Co., Ltd (Japan), Smith & Nephew (UK), Narang Medical Limited (India), Eli Lilly and Company (Indiana). F. Hoffmann-La Roche (Switzerland) as the key players in the global X-linked hypophosphatemia market.

Key Findings of the Study:

  • The Global X-linked Hypophosphatemia Market is projected to reach over USD 40,309 thousand by 2025 at a 6% CAGR during the review period of 2019 to 2025.

  • Asia-Pacific accounted for the largest market share, with Japan being the major contributor to the growth of the market.

  • The treatment segment is projected to register the highest CAGR of 3.6% during the forecast period as according to the statistics published in 2017 by the Food and Drug Administration (FDA), XLH affected an approximate of 3,000 children and 12,000 adults in the US.

  • Key manufacturers are adopting geographic expansions, corporate acquisitions, and product launches as growth strategies. Moreover, they are focusing on e-commerce for distribution.

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Healthcare Contract Manufacturing Market Trends Analysis Research Report 2020-2027

 Global healthcare contract manufacturings consist of regions namely the Americas, Europe, Asia Pacific, and the Middle East and Africa.

The Americas holds the largest share of the global healthcare contract manufacturing market owing to the rising number of drug approvals as one of the factors fuelling the growth. The patent expiries of blockbuster drugs are creating a new opportunity to vendors to develop biosimilars at low cost. Thus, the market is anticipated entry of biosimilars and generics, which is likely to further strengthen the growth in this region.

The European market dominated the global healthcare contract manufacturings market owing to the high prevalence rate of various disease in the Eastern European regions.

The Asia Pacific region is anticipated to be the fastest growing region over the forecast period owing to the increasingly favorable government initiatives along with the improving healthcare infrastructure.

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Segmentation

The global healthcare contract manufacturing market is segmented on the basis of product, industry, type, and services.

On the basis of the product, the global healthcare contract manufacturing market is segmented into active pharmaceutical ingredients (API), final dosage formulations (FDF), advanced drug delivery products, OTC medicines and nutritional products, and others. Moreover, the finished dosage formulations (FDF) is segmented into a tablet, capsules, oral liquids, parenteral/injectables, and others.

On the basis of the industry, the global healthcare contract manufacturing market is segmented into pharmaceutical, biopharmaceutical, and others.

On the basis of the type, the global healthcare contract manufacturing market is segmented into sterile, non-sterile, and others

On the basis of the service, the global healthcare contract manufacturing market is segmented into oncology research, vaccines research, inflammation & immunology research, cardiology research, neuroscience research, and others.

Key Players

Some of key the players in the global healthcare contract manufacturings market are Patheon (Netherlands), Lonza (Switzerland), Evonik Industries (Germany), Teva Pharmaceutical Industries (Israel), Boehringer Ingelheim BioXcellence (Germany), Famar S.A. (Greece), Fareva Group (France), Vetter Pharma International (Germany), Mylan (U.S.), Recipharm (Sweden), Aesica Pharmaceuticals (U.K.), Althea Technologies (U.S.),  Aenova (Germany), Dishman Pharmaceuticals and Chemicals Limited (India), Catalent Pharma Solutions (U.S.), Kemwell Pvt. Ltd. (India), Jubilant Life Sciences Limited (India), Nipro Corporation (Japan), NextPharma (UK), Pfizer Central Source (U.S.), Royal DSM N.V. (Netherlands), Abbott Laboratories (U.S.), Amgen (U.S.), Apotex (U.S.), Aspen (U.S.), AstraZeneca PLC (UK), Aurobindo Pharma (India), Baxter International  (U.S.), BERLIN-CHEMIE (Germany), Biocon (India), Biogen (U.S.), Celltrion (South Korea),  Cipla (India), Coherus Biosciences (U.S.), Daiichi Sankyo (Japan), Dr. Reddy's Laboratories (India), Eli Lilly and Company (U.S.), Emcure Pharmaceuticals (India), Eurofarma Laboratories (Brazil), Gedeon Richter (Hungary), Gilead Sciences (U.S.), GlaxoSmithKline (GSK) Plc (U.S.), Hospira (U.S.), Impax Laboratories (U.S.), Intas Pharmaceuticals (India), Janssen Pharmaceuticals (U.S.), Lupin (India), Merck and Co. Inc. (U.S.), Mitsubishi Tanabe Pharma (Japan), Momenta Pharmaceuticals (U.S.), Natco Pharma (India), Nexus Pharmaceuticals (U.S.), Novo Nordisk (Denmark), Orchid Chemicals & Pharmaceuticals (India), Par Pharmaceutical (U.S.), Parenteral Drugs (India), Piramal (India), Roche Holding (Switerzland), Sanofi (France), Synthon (Netherlands), Teva Pharmaceuticals (Israel), Valeant Pharmaceuticals (Canada), Zentiva (Czech Republic), Zhejiang Huahai Pharmaceutical (China), Zydus Cadila (India), and others.

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Structural Heart Devices Market: Drivers, Restraints, Opportunities, and Threats (2020-2027)

 Structural heart disease known as a non-coronary anomaly of the heart, therefore not disturbing the blood vessels in the heart. The structural heart diseases refer to cardiac defects which are inherited by birth and can be developed later in life. Common structural heart condition includes atrial septal defect, ventricular septal defect, paravalvular leak, arterial or venous fistula, patent foramen oval and congenital heart disease. The rise in the frequency of structural heart diseases and a rise in demand for minimally invasive techniques are factors that drive the growth of the market. Advanced products such as sutureless heart valve cost pointedly higher than earlier available products. This double prices of the sutureless device will limit the adoption of the equipment’s, which in turn will restrain the growth of the market.The global structural heart devices market is expected to grow at CAGR of 10.4% during the forecast period (2018–2023).

Segmentation

The global structural heart devices market has been segmented on the basis of type, indication, procedure, and end-user. On the basis of type, the market has been classified as heart valve devices, occluders and delivery systems, annuloplasty rings, accessories, and other devices. The heart valve devices are segmented into transcatheter heart valves and surgical heart valves. The surgical heart valves are further sub-segmented into tissue heart valves and mechanical heart valves. On the basis of indication, the market has been classified as valvular heart disease, cardiomyopathy, congenital heart defects, and others. The valvular heart disease is segmented into regurgitation and stenosis.  On the basis of procedure, the market has been classified as Replacement Procedures and repair procedures. The Replacement Procedures is segmented into TAVR procedures and SAVR procedures. The repair procedures are segmented into closure procedures, annuloplasty, valvuloplasty, and TMVR procedures. On the basis of end-users, the market has been classified as hospitals, ambulatory surgery centers, and others.

Regional Analysis

The Americas is projected to lead the structural heart devices market in the forecast period. Rising rate in a number of surgeries due to factors such as diabetes, high blood pressure, and others contribute majorly to the growth of the market. Increasing healthcare awareness, advancement in technology, medical tourism, and an increase in disposable income are some other factors that boost the growth of the market.

The European market is expected to hold the second largest market share as structural heart devices market is most common in Germany. The European market is projected to grow because of the increase in elderly population, growing prevalence of diabetes, and obesity in the region.

Asia-Pacific was projected to be the fastest growing region for the global structural heart devices market in 2018. The market is expected to witness growth owing to the rising patient population, changing lifestyle, and growing elderly population. This is expected to provide favorable backgrounds for the market to grow.

The Middle East and Africa accounts for the least share due to stringent government policies and low per capita income.

Key Players

Some of the key players in the global structural heart devices market are Edwards Lifesciences Corporation (US), Medtronic plc (Ireland), Abbott (US), Boston Scientific Corporation (US), and LivaNova plc (UK), ST. Jude Medical, Biomerics, Comed BV, JenaValve Technology, Inc., CardioKinetix, Cook Group Incorporated (US), Endologix Inc. (US)., and W. L. Gore & Associates, Inc. (US).

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Healthcare Claims Management Market Dynamics, Segments and Supply Demand 2020-2027

 Healthcare claims management process comprises of various tasks such as organization, billing, filling, updating, and processing of medical claims related to the diagnosis, treatment, and medication of patients. The healthcare claims management market is driven by factors such as improved focus on quality healthcare services and adoption of cloud-based technology related services. However, integration of claims management solutions, data breaches, loss of confidentiality, and lack of skilled IT professionals in healthcare are some of the factors restraining the growth of this market. 

The global healthcare claims management market is currently dominated by many market players. The key players in the market are engaged in new product launches and strategic collaborations to strengthen its market position. For instance, IBM’s IPD Ultera for Disability Claims provides an integrated “disability claims management workbench”, specific to disability claims processing and without the need for a large-scale replacement project.

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Regional Analysis

The market in the Americas is expected to dominate the global healthcare claims management market during the forecast period owing to the of new and innovative treatments & technologies. Also, heavy inflow of investments by various government agencies to improve healthcare IT infrastructure is expected to create opportunities for healthcare claims management solutions providers. According to the National Health Expenditure Accounts (NHEA), U.S. health care spending grew 4.3 percent in 2016, reaching $3.3 trillion or $10,348 per person which accounted for 17.9 percent. Moreover, the increasing investment in the healthcare infrastructure and services in Asia-Pacific offers huge market potential for the players to grow in healthcare claims management solutions market. In addition, proactive government initiatives to spread awareness about the benefits of this technology among the masses have supplemented the market growth. The market in the Middle East & Africa is likely to account for the smallest share of the global healthcare claims management market. The market growth in this region can be attributed to the high cost of healthcare IT solutions.

Segmentation

The global healthcare claims management market has been segmented into component, delivery mode type and end-user.

The market, based on component, has been segmented into software and services.

The market, by delivery mode, has been segmented into on-premise and cloud based.

The market, by type, has been segmented into integrated and standalone.

The market, by end-user has been segmented into healthcare payers and providers.

Key Players

Some of the key players in the global healthcare claims management market are Cerner Corporation, McKesson Corporation, athenahealth, Inc., eClinicalWorks, Optum, Inc., Conifer Health Solutions, nThrive, Inc, Avaya Inc., Oracle Corporation, Infor Inc., Allscripts Healthcare Solutions, Inc., Accenture plc., IBM Corporation, Cognizant Technology Solutions Corporation and Genpact Limited.

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Research report explores the Arrhythmia Monitoring Devices Market for the forecast period, 2020-2027

 The global arrhythmia monitoring devices market, during the forecast period 2016 to 2024, will register growth at a CAGR of 6.44%. The market for arrhythmia monitoring devices is set to reach USD 8,087.4 million by 2024. As per the market analysts, the global market is anticipated to witness growth owing to the factors such as the growing usage of telecardiology as well as the on-going development of smart cardiac monitors. However, the market will face challenges and restraints due to product recalls  and associated complications during the forecast period 2016 to 2024. 

The portability of cardiac arrhythmia monitoring devices in the market is set to play a key role in determining the growth potential during 2016 to 2024years. Analysts have also studied the global market to understand potential threats and challenges the market companies could face. Although the market is poised to grow at a fast pace across device type, application, and end-user segments, factors such as the complications related to such devices could slow down the market's growth worldwide. 

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Market Segmentation 

The arrhythmia monitoring devices market has been segmented into device type, application, and end-user. Based on the segment which is device type, the market is categorized on the basis of event monitor, Holter monitor, resting ECG, and others. The global market for arrhythmia monitoring devices is further segmented based on application into tachycardia, bradycardia, and others. Furthermore, the market, on the basis of end-user is segmented into hospitals and clinics, and others. 

The global market research report covers all the aspects of the market based on the segmental analysis of these device type, application, and end-user segments. Analysts have also studied the global market's regional markets spread across many continents and countries. The device type, application, and end-user segments along with their sub-segments have been analyzed and companies functioning in the market across these segments are profiled and analyzed based on input and feedback from market based decision makers as well as primary and secondary sources. The market research report presents analysis based information for companies functioning in the market. 

Regional Overview 

High expenses associated with remote cardiac arrhythmia monitoring may hinder the market growth. The market research report suggests that companies in the market could be supported by innovation in product as well as the on-going technical development during the forecast period. The market is set to register growth at a high CAGR owing to these key factors. The market is spread across North America, Europe, Asia-Pacific, and other parts of the world. The global market research report reveals that APAC, North America, and Europe regional arrhythmia monitoring devices markets will dominate the global market for arrhythmia monitoring devices during the forecast period 2016 to 2024. As per arrhythmia monitoring devices market analysts, the market is set to witness tremendous growth across Holter monitor, tachycardia, and hospitals and clinics segments in North America which covers arrhythmia monitoring devices markets across the United States, Canada, Mexico and several other regional markets. Companies active in the market are also analyzed and studied in the arrhythmia monitoring devices market research report. 

The market for Europe covers smaller market segments of Germany, Italy, France, and the United Kingdom. Additionally, the market research report covers the Asia-Pacific region covering markets from India, China, Japan, Australia, and others. The market is also spread across the rest of the world. The market report covers all such regions including the Middle East, Africa, Brazil, and others. 

Competitive Landscape 

Arrhythmia monitoring devices has seen increased demand over the years, due to the high accuracy and efficiency provided by arrhythmia detection and the growing requirement for continuous cardiac rhythm monitoring. Companies functioning in the global arrhythmia monitoring devices market are also being challenged due to the rise in recalls of arrhythmia monitoring devices and cost and budget related concerns among SMEs. Mergers and acquisitions by market companies are anticipated to help the market during the forecast period 2016 to 2024. As the market is set to register a high CAGR of 6.44% and is also anticipated to reach a USD 8,087.4 million by 2024, the report highlights key areas companies need to focus on. The report suggests that the market will see a healthy growth in the long run till 2024. Based on SWOT analysis and market’s analysis based on Porters’ Five Force Model presented in the market report. Mergers and acquisitions by market companies are anticipated to help the market during the forecast period 2016 to 2024.  

Industry News 

This year, the Marlborough, Massachusetts-based medical technology corporation increased its heart device acquisitions, taking a $90 million equity interest in valve treatment business Millipede and purchasing the remaining stock of ablation remote monitoring manufacturer Securus Medical Group for $40 million.  Anti-arrhythmic medications or cardiac ablation, where in radiofrequency or cryothermal energy is applied to regions of the heart responsible for the disturbed heart rhythm, are often used to care for patients with heart failure, a common type of erratic heartbeat. Atrial fibrillation affects at least 2.7 million Americans, increasing the risk of blood clots and stroke.

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Neurovascular Devices Market Current Trends, SWOT Analysis, Strategies, Industry Challenges, Business Overview and Forecast Research Study 2027

 The global Neurovascular Devices Market will grow at a CAGR of 8.8% during the forecast period 2014 to 2023. The market for neurovascular devices is set to reach US$3.1 billion by 2023. As per Neurovascular Devices Market analysts, the global market is anticipated to witness growth owing to the factors such as top firms trying to ramp up their manufacturing capacity as well as increase in technological innovations. However, the Market will face challenges and restraints due to unfavorable reimbursement scenarios and the high cost of neurovascular devices during the forecast period 2014 to 2023.

The consistently rising consumption of advanced neurovascular devices in the Market will support the growth. As per Market analysts, Neurovascular Devices Market based companies will face certain challenges during the forecast period 2014 to 2023. The Market research report provides in-depth analysis of the product, end-users, and therapeutic application segments. The Market research report presents factors such as lack of proficient neurosurgeons that could slow down the Market's growth.

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Market Segmentation

The Neurovascular Devices Market has been segmented into product, end-users, and therapeutic application. Based on the segment which is the product, the market is categorized on the basis of embolization devices, support device, and aneurysm coiling. The global market for neurovascular devices is further segmented based on end-users into hemorrhagic and ischemic strokes. Furthermore, the market, on the basis of therapeutic is segmented into ambulatory surgical units and hospitals.

The Market report offers comprehensive study of the Neurovascular Devices Market segments including product, end-users, and therapeutic application. The analysts have also studied the Market's spread across the regional markets across many of the Market’s segments at country levels. The product, end-users, and therapeutic application segments spread across the Market along with the subsegments are studied. The global market for neurovascular devices is spread across various product and service based segments. The Market research report highlights these key segments and offers forecasts based on primary and secondary data. The global Neurovascular Devices Market research report presents key company profiles of organizations active across the Market.

Regional Overview

Expensive neurovascular devices may hinder the Market growth. The Market research report suggests that companies in the Market could be supported by companies exploring new ways to maintain their business as well as expanding patient pool  during the forecast period. The Market is set to register growth at a high CAGR owing to these key factors. The Market is spread across North America, Europe, Asia-Pacific, and other parts of the world. As per Market analysts, Neurovascular Devices Market is set to witness tremendous growth across product, end-users, and therapeutic application segments. The global Market’s North American region covers Markets across the United States, Mexico, Canada, and others. Businesses present in the Market are also profiled and their strategies have been presented in detail in the Market research report.

The Market across the European region covers Italy, France, Germany, and the United Kingdom. Furthermore, Neurovascular Devices Market research report provides details about the APAC region covering Markets from China, India, Australia, Japan, and others. The Market is also active across several other parts of the world. The Market report covers all these key regions including the Middle East, Africa, Brazil, and others active in the global Market.

Competitive Landscape

Neurovascular devices has seen tremendous growth, due to interventional therapies witnessing massive growth and high demand for minimally invasive procedures. However, significant cost of neurovascular devices and the emergence of complications during neurovascular surgeries would challenge the companies active in the Market. Furthermore, companies using growth strategies to stay ahead in the global Market are expected to help the market during the forecast period 2014 to 2023. As Neurovascular Devices Market report suggests that the Market will register a CAGR of 8.8% and reach a US$3.1 billion by 2023, the market report highlights key areas Market based companies need to focus on. The Market research report projects a long term growth till 2023. Based on Market’s analysis on the basis of SWOT and Porters’ Five Force Model, Neurovascular Devices Market will rise during the forecast period 2014 to 2023, however the companies need to move ahead with caution. The Market research report highlights such key areas.

Industry News

Lazarus Effect, a medical equipment corporation with a highly acute ischemic stroke that is licenced in Europe but not in the United States, was acquired by Medtronic. The contract is a financial transaction of 100 million dollars, according to standard closing conditions. In the Medtronic neurovascular division of the Restaurant Therapy community Lazarus Effect would be included. Medina Medical, a provider of medical devices which is now in Medtronic's neurovascular business, developed a system to treat the cerebral aneurysm on 31 August. Lazarus' nitinol net cover plys over a stent recorder during the recuperation of the clot and wraps the clot around the stent.

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