Arteriovenous malformation Market: Drivers, Restraints, Opportunities, and Threats (2020-2027)

 Market Highlights

Increasing prevalence of neurological/brain disorder like arteriovenous malformation, epilepsy, rising need for better treatment for rare disease, increasing investment of biotechnology and pharmaceutical industries in R&D, and availability of funds drive the growth of the market. Moreover, increasing government support for research & development, changing lifestyle, and rapid development in technology will fuel the market growth during the forecast period. On the other hand, higher cost of the treatment procedure may slow the market growth during the review period.

Over the last decade, the number of hospitals has increased to a great extent, which has influenced the growth of the market positively. Moreover, increasing demand for better treatment and changing reimbursement policies have fueled the market growth.

The global arteriovenous malformation market is expected to grow at a CAGR of ~6.1% during the forecast period 2017-2023.

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Regional Analysis

The Americas dominate the global arteriovenous malformation market owing to the presence of huge patient population, high health care spending, and increasing government support for research & development.     

Europe holds the second largest share of the global market. The increasing focus of various government agencies on treating various brain disorders or brain injuries such as epilepsy and depression will have a positive impact on the growth of the market. The growing public awareness will boost the adoption of these devices in the European market.  

Asia Pacific is the fastest growing arteriovenous malformation market across the globe. Japan holds a major share of the regional market due to availability of technology and huge healthcare spending. Rapidly developing economy, increasing healthcare expenditure, and government initiatives for research & development will drive the market in China and India over the assessment period.      

The Middle East and Africa hold the least share of the global market due to limited availability of medical facilities. The UAE, Saudi Arabia, and Kuwait are expected to drive the Middle East & African market whereas, the African region is expected to witness a moderate growth.  

Segmentation

The global arteriovenous malformation market is segmented on the basis of types, diagnosis, treatment, and end user. On the basis of types, it is segmented into true arteriovenous malformation, occult or cryptic AVM or cavernous malformations, venous malformation, hemangioma, and dural fistula. On the basis of diagnosis, it is segmented into physical examination, blood test, brain scans, and others. Brain scan is further segmented into computerized tomography (CT) scan, Magnetic Resonance Imaging (MRI), magnetic resonance angiography (MRA), and electroencephalography (EEG). On the basis of treatment, the market is segmented into endovascular embolization, neurosurgery and others. On the basis of the end user, it is segmented into hospitals & clinics, research laboratories and others.

Key Players

Some of key the players in the market are Toshiba Medical Systems Corporation (Japan), Carestream Health (U.S.), Nihon Kohden Corporation (Japan), Electrical Geodesics Inc. (U.S.), Fujifilm Holdings (Japan), GE Healthcare (U.S.), Siemens Healthcare(U.S.), Philips Healthcare (U.S.), Shimadzu Corporation (Japan), Masimo Corporation (U.S.), Hologic (U.S.), Esaote (Italy), and others.

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Desmoid Tumors Market – Qualitative Insights by 2027

 Market Highlights

Desmoid tumors are the benign fibrous growths which usually develops in the fibrous tissue of the body, commonly in the arms, legs or midsection, and sometimes in the head and neck. According to the U.S National Library of Medicine, Desmoid tumors are very rare as the rate of occurrence is estimated to be 1 to 2 per 500,000 people worldwide. It is also stated that nearly 900 to 1,500 new cases are registered per year in the United States. Tumors associated with familial adenomatous polyposis (FAP) are less common than sporadic desmoid tumors. On the molecular level, desmoid tumor is characterized by one of the two mutations in the gene i.e. mutations in the adenomatous polyposis coli (APC) gene, or in the β-catenin gene, CTNNB1. During diagnostic procedures CTNNB1 mutation is detected, especially, when pathological differential diagnosis is difficult. The symptoms of desmoid tumors include a painless swelling or lump, pain and obstruction of the bowels, limping, pain caused by compressed nerves or muscles, and others. For the diagnosis of desmoid tumor there are many non-invasive methods available to detect desmoid tumor which include ultrasound, MRI scan, and CT scan. The actual diagnosis of this tumor can be made only after examining a small piece of the tumor by a trained pathologist.

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Rising demand of effective chemotherapeutic agents, high unmet needs of current treatment, and increase in research and development expenditure will promote the growth of desmoid tumors market. According to the Desmoid Rare Foundation, individuals within the age group of 15 and 60 are more likely to get affected. It is also stated that the condition is more prevalent in women than in men (2:1).

High cost of treatment & management of desmoid tumors and related disorders, and lack of infrastructure in middle and low income countries may hamper the growth of the market.

It is estimated that desmoid tumors market is expected to grow at a CAGR 4.5% during the forecast period of 2017-2023.

Regional Analysis

The Americas dominate the desmoid tumors market owing to the rising awareness among people, and increasing healthcare expenditure. As per the facts suggested by Centers for Disease Control and Prevention (CDC), it is found that out of total annual healthcare expenditure, 86% is for people with chronic health conditions in the United States. Furthermore, increasing participation of bigger players and new marketers towards advancement in treatment approaches have also attracted a great deal of attention.

Europe holds the second position in the desmoid tumors market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the market in Europe region.

Asia Pacific is the fastest growing desmoid tumors market owing to the huge patient pool and developing healthcare technology.

The Middle East & Africa has the lowest market for desmoid tumors market due to lack of technical knowledge and poor medical facilities.

Segmentation

The desmoid tumors market is segmented on the basis of diagnosis, treatment, and end-user.

On the basis of diagnosis, market is segmented into biopsy, electron microscopic examination, immunohistochemical analysis, others

On the basis of treatment, market is classified into surgery, radiation therapy, anti-inflammatory medication, hormone therapy, chemotherapy, novel molecular-targeted therapy, others. Novel molecular-targeted therapy is further segmented into gleevec based therapy, and sorafenib based therapy

On the basis of end-user, market is segmented into hospital, clinics, and others. 

Key Players

Some of key the players in the market are Amgen Inc., Novartis AG, Abbott Laboratories, Bayer AG, AbbVie Inc., Beckman Coulter Inc., Stryker Corporation, Debiopharm Group, F. Hoffmann-La Roche Ltd, and others.

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MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.j

Contact

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Dysfunctional Uterine Bleeding Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

 According to the American Society for Reproductive Medicine, dysfunctional uterine bleeding is most common during puberty and menopause. It can also can occur at any time in women due to hormonal imbalance. Polycystic ovary syndrome (PCOS), endometriosis, uterine polyps, uterine fibroids, Sexually Transmitted Diseases (STDS) are common causes of dysfunctional uterine bleeding. It can be diagnosed by performing an endometrial biopsy or blood tests.

The rising prevalence of uterine disorders such as endometrial cancer among women, availability of reliable diagnostic tests, and overall demand for new treatment for uterine bleeding drive the market growth.  Increasing number of awareness drives and campaigns regarding cancer among women further influence the market growth.

The global dysfunctional uterine bleeding market is expected to grow at a CAGR of 8.2% during the forecast period.

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Major Players in Dysfunctional uterine bleeding Market:

Some of the key players in the global market are B. Braun Melsungen AG (Germany), Hologic Inc. (U.S.), Karl Storz Gmbh & Co. KG (Germany), Medgyn Products, Inc., Olympus (Japan), Richard Wolf GmbH (Germany), Stryker (U.S.), Xion Medical GmbH (Germany), Cadila Pharmaceuticals Ltd. (India), Torrent Phamraceuticals (India).

Regional Analysis

America is the largest market for dysfunctional uterine bleeding market owing to the rising prevalence of uterine cancer and other uterine disorders among women. According to the American Cancer Institute, about 61,380 new cases of uterine cancer will be diagnosed in 2017 and 8% of the urine cancers are sarcomas.

Europe is the second largest market owing to an increasing demand for diagnosis and treatment measures for uterine cancer, fibroids and other disorder, and increasing emphasis on women healthcare. Additionally, availability of funds for research and development activities accelerates the market growth in the European countries.

The market in Asia Pacific is expected to grow at the fastest pace and is driven by the increasing prevalence of menstrual disorders, and sexually transmitted diseases (STI) among women in developing nations. Furthermore, increasing awareness about STI and preventive measures to be taken also influences the market growth.

The Middle East & Africa also show a steady rise in the market owing to increasing focus on women and child health, and need of primary care services in developing regions.

Segmentation

The global dysfunctional uterine bleeding market is segmented on the basis of type, diagnosis, treatment, and end user.

On the basis of type, market is segmented into ovulatory, and anovulatory.

On the basis of diagnosis, the market is segmented into hysteroscopy, ultrasonography, dilation and curettage, endometrial biopsy, and others.

On the basis of treatment, the market is segmented into pharmacologic treatment, hysterectomy, endometrial ablation, and others. The pharmacologic treatment includes oral contraceptives, estrogen, progestins, desmopressin and others.

On the basis of end user, the market is segmented into hospitals, clinics, diagnostic centers, pharmaceutical companies, and others.

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Achondrogenesis Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

 Achondrogenesis is a genetic rare disease that affects cartilage and bone development. The condition is characterized by narrow chest, rounded abdomen, and extremely short limbs. Achondrogenesis includes various symptoms such as, abdominal distention, flat face, anteverted nares, frontal bossing, lethal skeletal dysplasia, hydropsfetalis, abnormal enchondral ossification, and many others. According to the U.S National Library of Medicine, the incidence of 1A and 1B, whereas achondrogenesis type 2 occur in 1 in 40,000 to 60,000 newborns. Majorly three types of achondrogenesis are known and out of these three, type 1B (ACG1B) is most severe condition. According to an article published in GeneReviews book, it is found that SLC26A2 is the only mutated gene known to cause ACG1B.

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A number of factors such as, rise in facilities for patients affected by rare diseases, increasing awareness among people, increasing government assistance, and improvement in regulatory framework are propelling the growth of achondrogenesis market. Presence of mutated gene in the family history is also fuelling up the market to a great extent. As per the information suggested by National Center for Advancing Translational Sciences (NCATS), achondrogenesis type 1A and type 1B occurs due to autosomal recessive inheritance which means each parent carry one copy of the mutated gene. However, it is also reported that achondrogenesis type 2 is an autosomal dominant disorder and typically found in people with no history of gene mutation in their family. Despite these drivers, there are some issues associated with achondrogenesis market. Challenges in research and development, and lack of skilled healthcare professionals in developing countries may hamper the growth of market.

It is estimated that achondrogenesis market is expected to grow at a CAGR 3.9% during the forecast period of 2017-2023. 

Regional Analysis

The Americas dominate the achondrogenesis market owing to the rise in awareness among people, and high healthcare expenditure. According to the Centers for Disease Control and Prevention, in 2015, the total health expenditure in the United States was reported as USD 3.2 trillion and hospital care accounted for a share of 32.3%.

Europe holds the second position in achondrogenesis market. It is expected that the support provided by government bodies for research & development and improvement in reimbursement policies in healthcare will drive the market in Europe region.

Asia Pacific is the fastest growing achondrogenesis market owing to the huge patient pool and developing healthcare technology.  

Segmentation

The achondrogenesis market is segmented on the basis of type, diagnosis, and end-users.

On the basis of type, market is segmented into surgery achondrogenesis type IA (Houston-Harris type), achondrogenesis type IA (Houston-Harris type), and achondrogenesis type II (Langer-Saldino type).

On the basis of diagnosis, market is classified into physical examination, molecular genetic testing, and biochemical testing. Physical examination is further classified into X-ray, ultrasound, and others. Molecular genetic testing is also further segmented into Chorionic Villus Sampling (CVS), aminocentesis, and others.

On the basis of end-users, market is segmented into hospital & clinics, diagnostic centers, research & academic institutes, and others.

Key Players

Some of key the players in the achondrogenesis market are Cook, Thermo Fisher Scientific, CooperSurgical Inc., Illumina, Inc., Siemens AG, FUJIFILM Holdings Corporation, Koninklijke, Philips N.V., Stryker, Toshiba Corporation, Invivoscribe, Abbott Molecular Inc., INVITROGEN CORPORATION, Roche Molecular Systems, Inc., and others.

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Corneal Transplant Market 2020 Analysis, Industry Size, Share Leaders, Current Status by Major vendors and Trends by Forecast to 2027

 Corneal transplant is a surgical procedure performed for the treatment of diseased cornea. Important indications for corneal transplant are keratoconus, keratitis, and corneal stromal dystrophies. The success rate of the treatment is found to be high, which support the market growth.

Rising prevalence of vision impartment and eye diseases such as diabetic retinopathy in geriatric population and diabetes across the globe drive the global market. Additionally, rising awareness about organ donation and its importance, especially, in the developing countries likely to propel the market growth.

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Cost of corneal transplant varies depending upon the region, availability of services, and skilled and qualified professionals. Major difference in the cost is observed, i.e. it is found to be high in the developed countries and low in developing countries still maintaining qualitative care. Therefore, cost effective of the treatment would affect the market growth.

The global corneal transplant market is expected to grow at a CAGR of 10.8% during the forecast period.

Major Players in Corneal Transplant Market:

Some of the key players in the global market are CryoLife, Inc. (U.S.), Exactech, Inc. (U.S.), Köhler GmbH (U.S.), Lifeline Scientific (U.S), LifeCell Corporation (U.S.), Medtronic (U.S.), and Organogenesis Inc. (U.S.).

Regional Analysis

Europe is the largest market for corneal transplant which will exhibit positive growth in the near future due to rising prevalence of diabetes in the European countries and availability of treatment options. According to the World Health Organization, about 60 million Europeans have diabetes and its prevalence is relatively high among people over 25 years.

America is the second leading corneal transplant market across the globe owing to an increasing demand for corneal transplant surgery, and rising prevalence of eye diseases, and vision impairment among people in the U.S.

Asia Pacific market is expected to grow rapidly owing increasing prevalence of chronic diseases such as diabetes, diabetic retinopathy, and obesity. India is one of the international medical tourism destinations across the world, which further exhibits growth opportunities for the corneal transplant market due to availability of cost-effective treatment and rising success rates. Furthermore, the increasing healthcare expenditure by developing countries in Asia Pacific region also contributes to the market growth.

The Middle East & African market is growing steadily owing to rising demand for ophthalmic products and services, and available treatment options.

Segmentation

The global corneal transplant market is segmented on the basis of type, indication, and end user.

On the basis of type, the market is segmented into penetrating keratoplasty, endothelial keratoplasty, descemet stripping automated endothelial keratoplasty (DSAEK), corneal graft, corneal limbal stem cell transplant, and others.

On the basis of indication, the market is segmented into fungal corneal ulcer, bullous keratopathy, keratoconus, keratitis, corneal stromal dystrophies, and others.

On the basis of end user, the market is segmented into hospitals, eye clinics, and others.

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Global Inguinal Hernia Market Show Steady Growth: Study 2027

 Inguinal hernia is a condition in which a part of small intestine bulges through its walls. It is one of the types of hernia, which is the most common in both the developing and developed countries across the globe.

The global inguinal hernia market is expected to show a high growth over the forecast period owing to rising number of patients with inguinal hernia and increasing number of surgical procedures performed for hernia repair.  Furthermore, growing demand for hernia repair devices boost the market growth. However, high cost hernia repair devices restrains the growth of the market in nations in Africans region and other developing countries.

The global inguinal hernia market is expected to grow at a CAGR of 10.7% during the forecast period.

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Major Players in Inguinal hernia Market

Some of the key players in the global market are Ethicon, Inc. (U.S.), Medtronic (U.S.), C.R. Bard, Inc. (U.S.), Atrium (U.S.), W.L. Gore & Associates Inc. (U.S.), Acelity (U.S.), and B Braun Melsungen AG (Germany).

Regional Analysis

America is the largest market for inguinal hernia owing to rising prevalence in the U.S. and increasing surgical procedures cases such as groin hernia repair.

Europe is the second largest market owing to increasing prevalence of inguinal hernia and extensive demand for hernia repair devices. The U.K is expected to be the largest market in Europe over the review period.  According to the New England Journal of Medicine, in 2014 more than 90,000 surgical intervention for inguinal hernia were performed in Europe.

In Asia Pacific, rising demand for laparoscopic procedures for inguinal hernia. India is expected to be the largest market in Asia Pacific followed by China and Japan.

The Middle East & Africa also shows a steady rise in the market owing to extensive use of hernia mesh devices for surgeries in the Middle East. In the Middle East, Iran is expected to be the largest market followed by Saudi Arabia. In Africa, high cost of hernia repair restrained the market growth.

Segmentation

The global inguinal hernia market is segmented on the basis of type, diagnosis, treatment and hernia mesh devices.

On the basis of types, market is segmented into direct and indirect hernia. 

On the basis of diagnosis, the market is segmented into physical examination and imaging test. Imaging tests is further segmented into abdominal ultrasound, CT scan and Magnetic Resonance Imaging (MRI).

On the basis of treatment, the market is segmented into open hernia repair, laparoscopy, and others.

On the basis of hernia mesh devices, the market is segmented into synthetic mesh, and biologic mesh.

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About Market Research Future:

MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.j

Contact

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Serotonin Syndrome Market Size, Share, Demand, Financial Overview, Key Developments, Swot Analysis and Forecast to 2027

 According to the Market Research Future (MRFR) analysis, the market for serotonin syndrome is expected to hit $400 million, with CAGR estimated to rise by 2.3% from 2017-2023 (forecast period). The serotonin syndrome market report is an informative and in-depth analysis that offers a detailed overview of the industry, including recent developments and potential proportions of the demand for serotonin syndrome in terms of products and services. 

Serotonin syndrome is a group of symptoms such as high body temperature, increased reflexes, anxiety, tremor, sweating, diarrhea, dilated pupils, etc. due to the use of serotonergic drugs. Severe complications, such as seizures and extensive muscle breakdown, can lead to death. The case of Libby Zion in 1984 is an example of death from serotonin syndrome. Serotonin syndrome is usually caused by a synergistic effect of two or more serotonergic drugs, commonly including serotonin norepinephrine reuptake inhibitor (SNRI), selective serotonin reuptake inhibitor (SSRI), monoamine oxidase inhibitor (MAOI), tricyclic antidepressants (TCAs), amphetamines, etc. Many drugs with a high potential to induce serotonin syndrome include dextromethorphan, buspirone, L-tryptophan, St. John's wort, metoclopramide, ondansetron, etc. There is no laboratory test supporting the diagnosis of serotonin syndrome.

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Market Dynamics

Treatment for serotonin syndrome requires the discontinuation of medications that lead to the disorder. Many treatments for treating related symptoms can be used in severe cases. For severe cases with life-threatening gastrointestinal decontamination, using activated charcoal is performed. Sedatives such as benzodiazepines are used in agitated patients. High fever is a typical symptom of serotonin syndrome that reaches exceptionally high temperatures of more than 40 centigrade. Cooling measures can be required to regulate hyperthermia. Serotonin antagonist, such as cyproheptadine, may be necessary.

Market restraints on serotonin syndrome are the low number of cases and the equally small number of fatalities associated with serotonin syndrome in less than 1 % of cases of serotonin syndrome caused by disease-causing medications. Mild symptoms occur in approximately 15% of SSRI overdoses.

Segmentation

The global market for serotonin syndrome is segmented on drug treatment and end-users. 

Based on drug treatment, the market for serotonin syndrome has been segmented as serotonin antagonists, supportive care(anti-hyperthermics, Muscle relaxants, the control of autonomic instability, antihypertensive, and others).

Based on the end-users, the market has been segmented as hospitals, point of care, and others.

Regional Analysis 

The global serotonin syndrome market is segmented into North America, Europe, the Asia Pacific, and the Middle East & Africa.

North America is further segmented into the United States and Canada. The United States accounts for the highest market share due to the increased use of medicines and higher expenditure on healthcare. The rapid consumer adoption of emerging technology and devices in the United States is also an essential factor driving the global market for serotonin syndrome. 

Europe is the second-largest market due to high disposable incomes and increased awareness. 

The Asia Pacific region is projected to have the most potential for the future and is predicted to be led by China and India. 

The Middle East & Africa market is dominated by Gulf nations, especially Saudi Arabia and the UAE. Africa's regions are projected to experience modest growth due to weak economic, political conditions, and low healthcare penetration.

Key Players 

Key players profiled in the global serotonin syndrome market are Johnson & Johnson, AstraZeneca Plc., Eli Lilly and Company, Forest Laboratories Inc., Ciron Drugs & Pharmaceuticals Pvt. Ltd, GlaxoSmithKline plc., Merck & Co., Inc., Pfizer, Inc. and Sanofi S.A, and others.

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About Market Research Future:

MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions.j

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Market Research Future

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