Monday 24 February 2020

Sterilization Equipment market global industry by regions, type & applications during 2020-2023

Market Scenario
The Globalsterilization equipment market is expected to grow during the forecast period (2018–2023) at a CAGR ~7.0%.
Sterilization is a critical procedure in the healthcare industry and used to control the microbial populations which can affect the product quality. Numerous sterilization techniques are available in the market to control microbial growth. The increasing cases of hospital-acquired infections, an increasing number of surgical procedures, and increasing awareness about food sterilization and disinfection are expected to drive the growth of the market. Moreover, increasing research and development activities and technological advancements in sterilization techniques and increasing cases of chronic wounds are contributing to the growth of the market. According to a survey conducted by the American Professional Wound Care Association (2017), chronic non-healing wounds impact nearly 15% of Medicare beneficiaries (8.2 million) and a conservative estimate of the annual cost is USD 28 billion.
The rising cost of sterilization equipment, stringent government regulations and lack of awareness may hamper the growth of the market during the assessment period.
Segmentation
The global sterilization equipment market has been segmented on the basis of product, technology, and end–user.
On the basis of product, the market has been classified as heat sterilization, low-temperature sterilization, filtration sterilization, ionizing radiation sterilization. The heat sterilization segment has been further divided into dry heat sterilization and moist heat sterilization. The Low-temperature sterilization segment has been further divided into ethylene oxide sterilization, hydrogen peroxide sterilization, and others. The ionizing radiation sterilization segment has been classified as electron beams and gamma rays.
The technology segment has been divided into steam, forced convention, vacuum, gravity, and natural convection.
The market, by end–user, has been segmented into hospitals & clinics, research institutes, pharmaceutical companies, food & beverage industry, medical device companies, and other end–users.
The market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The sterilization equipment market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada.
The European sterilization equipment market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. 
The sterilization equipment market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The sterilization equipment market in the Middle East & Africa has been segmented into the Middle East and Africa.
Regional Market Summary
The Americas is likely to dominate the global sterilization equipment market owing to the increasingly strict sterility guidelines, increase in the number of surgical procedures due to rising geriatric population, the presence of a well-established healthcare system and adoption of highly advanced technology. According to the article published in 2016 by the National Council on Aging, about 80 percent of older adults have at least one chronic disease and 68 percent have at least two.
The European market is expected to be the second-largest sterilization equipment market. The market growth in this region can be attributed to the increasing government expenditure on healthcare and increasing research activities in the life sciences sector. Moreover, a growing number of road accidents in Europe region are contributing to the growth of the market in this region. According to an article published in 2015 by the World Health Organization (WHO), In Europe per year more than 2 million people suffer from road accidents and injuries related to it.
Asia-Pacific is expected to be the fastest-growing sterilization equipment market during the forecast period owing to the increasing prevalence of chronic diseases, increasing number of hospitals and research institutes in Asia and growth in healthcare and biotech industry. According to the World Health Organization (WHO), the geriatric population in China in the year 2013 was 22.6 million, which is expected to show a massive growth and reach 90.4million by 2050.
The market in the Middle East & Africa is expected to hold the smallest share of the global sterilization equipment market due to an underdeveloped healthcare sector, lack of technical knowledge, and poor research and healthcare facilities.
Key Players
Some of the key players in the global sterilization equipment market are 3M, STERIS plc., Getinge AB, Sotera Health, Advanced Sterilization Products (Division of Ethicon), Belimed, Anderson Products, Boekel Scientific, Celitron Medical, Technologies Kft., Fedegari Autoclavi S.p.A., Cantel Medical., LTE Scientific, Merck & Co., Inc, Midmark Corporation, and MMM Group.
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Endometrial Cancer market industry 2020 product specification, growth drivers, applications and forecast to 2023

Market Scenario
The abnormal growth of endometrium cells in the uterus is termed as endometrial cancer which is also known as uterine cancer. Endometrial cancer is diagnosed at an early stage as women experience abnormal vaginal bleeding. It is reported that endometrial cancer is the sixth most common cancer in women all over the world. The endometrial cancer market is expected to witness a tremendous growth owing to the rising prevalence of endometrial cancer. Other key factors such as the growing obesity among women, increase in menopausal hormone therapy, change in sedentary lifestyle, socioeconomic factors, growing consumption of unhealthy diet, increasing occurrence of Polycystic Ovarian Syndrome (PCOS), and increasing prevalence of breast or ovarian tumor are contributing towards the growth of the market.  Diabetes is another risk factor that leads to the development of endometrial cancer. According to the American Cancer Society,  endometrial cancer is four times common in diabetic women than in normal women. Such factors contribute to endometrial cancer among women.
However, factors such as high cost of diagnostic procedures, expensive treatments, and side effects associated with hysterectomy procedures are expected to restrict the market growth during the forecast period.
Research Methodology
Market Research Future research is conducted by industry experts who offer insights into industry structure, market segmentation, assessment, Competitive Landscape (CL), penetration, as well as on emerging trends. Besides primary interviews (~ 80%) and secondary research (~ 20%), their analysis is based on their years of professional expertise in respective industries. Our analysts also predict where the market will be headed in the next five to ten years, by analyzing historical trends and current market positions. Furthermore, the varying trends of segments and categories geographically presented are studied and are estimated based on the primary and secondary research.
  • Primary Research
Extensive primary research was conducted to gain a deeper insight into the market and the industry performance. In this particular report, we have conducted primary surveys (interviews) with key level executives (VPs, CEOs, Marketing Directors, Business Development Managers, and many more) of the major players who are active in the market. In addition to analyzing the current and historical trends, our analysts predict where the market is headed, over the next five to ten years.
  • Secondary Research
Secondary research was mainly used to collect and identify information useful for the extensive, technical, market-oriented, and commercial study of the global endometrial cancer market. It was also used to obtain key information about major players, market classification, and segmentation according to industry trends, geographical markets, and developments related to the market and perspectives. For this study, analysts have gathered information from various credible sources, such as annual reports, SEC filings, journals, white papers, corporate presentations, company websites, international organization of chemical manufacturers, some paid databases, and many others.
Segmentation
The global endometrial cancer market is segmented on the basis of diagnosis, treatment, and end-user. The endometrial cancer market, by diagnosis, is categorized into pelvic examination, transvaginal ultrasound, endometrial biopsy, dilation and curettage (D&C), and laparoscopy. On the basis of treatment, the market is segmented into hysterectomy techniques, radiation, hormone therapy, chemotherapy, and palliative care. The hysterectomy techniques category includes open abdominal hysterectomy, total vaginal hysterectomy, total laparoscopic hysterectomy, and robotic hysterectomy. The radiation category includes external radiation and internal radiation (brachytherapy). The hormonal therapy includes progestins, tamoxifen, luteinizing hormone-releasing hormone agonists, and aromatase inhibitors. The chemotherapy segment is categorized into paclitaxel, carboplatin, doxorubicin, and cisplatin. On the basis of end-user, the market is segmented into hospitals and clinics, ambulatory surgical centers, diagnostic centers, gynecology centers, feminist health centers, and others.     
On the basis of region, the global endometrial cancer market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The Americas is sub-segmented into North America and South America. The North American region is further segmented into the US and Canada. The European region is divided into two, namely, Western Europe and Eastern Europe. Western Europe is further classified into Germany, Italy, France, the UK, Spain, and the rest of Western Europe. The Asia-Pacific region is sub-segmented into Japan, China, India, Australia, the Republic of Korea, and the rest of Asia-Pacific. The Middle Eastern and African region is sub-segmented into the United Arab Emirates, Saudi Arabia, Oman, Kuwait, Qatar, and the rest of the Middle East and Africa.
Key players
Some of the key players in the global endometrial cancer market are Pfizer Inc., General Electric Company, Koninklijke Philips N.V., LUPIN, PHYTON, Bayer AG, Celgene Corporation, Johnson & Johnson, CooperSurgical Inc., LiNA Medical USA, Conceptus Inc., Hologic Inc., Karl Storz GmbH & Co. Kg, and Boston Scientific Corporation.
Regional Market Summary
The endometrial cancer market is dominated by North America owing to the rising prevalence of breast cancer. The US Breast Cancer Statistics projected 266,120 new cases of invasive breast cancer and 63,960 new cases of non-invasive breast cancer in 2018. Other factors such as increasing healthcare expenditure and increasing obesity within the female population drive the market growth in this region.
It is estimated that Europe stood second in the global endometrial cancer market owing to the increasing prevalence of ovarian cancer in this region. According to the Cancer Research UK in 2015, 7270 new cases of ovarian cancer were registered in the UK. Thus, the increasing prevalence of ovarian cancer in this region influences the growth of this market in this region.
Asia-Pacific was projected to be the fastest growing region for the global endometrial cancer market in 2017. The market is expected to witness growth owing to the rising prevalence of diabetes in women, changing lifestyle, and growing obesity within the female population. According to the American Diabetes Association, diabetes in South Asia is expected to rise by 150% from 2000 to 2035. This provides a favorable background for the market to grow.
The Middle East and Africa holds the least share in the global endometrial cancer market due to the presence of stringent government policies and poor economies. However, the market is expected to witness growth due to the rising healthcare expenditure, growing private sector in the healthcare domain, and insurance coverage in the Middle East.
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Epigenetics market dynamics, comprehensive analysis, business growth, prospects and opportunities 2019-2023

Market Scenario:
Epigenetics is the study of heritable changes in gene function not involving changes in the DNA sequence such as changes in a chromosome, phenotypic affecting gene activity and expression. The sources of heritable changes may be external from environmental factors, or internal factors such as age, disease and others. Examples of Epigenetics are DNA methylation and histone modification, which alters genes expression without altering the DNA sequence.
The drivers of Epigenetics market are growing risk factors and the associated increase in cases of cancer, increase in the R&D activities, developing pharmaceutical, and biotechnology sectors, application expanse of epigenetics and others. The development of high sensitive and selective tests, instrumentation and a concurrent rise in computational power is driving a massive adoption. The advancements such as the development of DNA and RNA modifying enzymes such as acetylases, methyltransferases, reverse transcriptase, ligases, and other protein-modifying enzymes has generated tremendous enthusiasm and concurrent faster market adoption.
The growing government support for biotechnology and growing partnership between academia and industry is another driver of growth. Attractive and critical advantages of technology exemplified by high-throughput molecular analysis of tissues, such as quick, cost-effective, efficient for less labor intensive and requires a lesser number of steps are the operational and economic driving factors of the market. Other technological developments include automation, advances in PCR technology, strategic and cross-functional nature of the molecular diagnostic technology and others.
High growth of biotech and growing number of start-ups are driving the development of proprietary technology. According to national venture capital association, the Biotechnology industry received the second largest amount of venture capital for the year 2016 and ended with a 17% rise in dollars as compared with the previous year.
The prime market constraints include prohibitive costs of molecular diagnostics, ha high cost of manufacturing, consolidated nature of the market has put a premium on the price other f the epigenetics products, nascent stage of technology and high power of firms relative to buyers.
Segments:
The global epigenetics market is segmented based on instruments, consumables, applications, technology, end users, and regions.
Based on instruments, the market comprises of NGS, spectrometer, PCR, software solutions and others.
Based on consumables, the market comprises of kit, enzymes, reagent, and others.
Based on application, the market comprises of oncology, developmental biology, drug discovery, cardiology, immunology, and others.
Based on technology, the market comprises of methylation, histone modification, and others.
Based on end users the market is segmented into academia and research, pharmaceutical and biotechnology industry and others.
Based on the regions, the market is segmented as North America, Europe, Asia Pacific Middle East and Africa and rest of the world.
Regional analysis
North America is the largest market in 2016 with the U.S. in the lead position owing to the faster uptake of technology, the gigantic biotech industry of the U.S., the presence of global and technology players, which is propelling the molecular diagnostics industry.
Europe led by Germany, U.K., and France accounts for the second-largest and second fastest market during the forecasted period. Asia is anticipated to expand at the most rapid rate led by Japan, China, South Korea and India.
The Middle East and Africa market are anticipated to generate a moderate growth on account of the impoverished industry landscape and low demand due to weak economic conditions.
Key Vendors Operating In The Global Epigenetics Market:
Some of the dominant vendors operating in the report are Bio-Rad (US), Illumina (US), QIAGEN (Netherlands), Thermo Fisher (US), Active Motif (US), Diagenode (Belgium), Agilent (US), Merck Millipore (US), Abcam (UK), New England Biolabs (US), PerkinElmer (US), Zymo Research (US), and others.
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Latest trends in the Optical Coherence Tomography market by 2020

Market Scenario
The global optical coherence tomography market is expected to grow at a CAGR of 8.9% during the forecast period 2017-2023.
Optical coherence tomography (OCT) is non-invasive imaging technology. The device generates a false-color representation of the tissue structure, on the micron scale in situ and in real time.  The OCT is analogous to ultrasound imaging, except that it uses light instead of sound. Early OCT systems were based on time-domain (TD) optical technology, but in recent years, Spectral-domain OCT (SD-OCT) succeeded TD-OCT and addressed some of its limitations. The SD-OCT is 50-1000 times faster than the TD technique. The swept-source OCT (SS-OCT) has also attracted a great deal of attention in OCT market, as SS-OCT provides >200,000 A-scans/second with ~5-7 µm axial resolution.
It is noted that rising prevalence of eye diseases and technological advancements are the key factors driving the optical coherence tomography market. The increasing prevalence of eye diseases has a significant impact on the optical coherence tomography market as it further pushes the demand for new, and advanced products of higher accuracy.
Increasing application of optical coherence tomography, rising approval from regulatory bodies, and favorable reimbursements are also fueling the market growth. OCT has been evolved as one of the most important imaging technique in various medical applications. OCT is an optical analog of intravascular ultrasound in cardiology, used to examine the coronary arteries. There are various products in the market for cardiovascular applications such as Dragonfly imaging catheter and C7-XR OCT system by Abbott, Lunawave - Coronary imaging console by Terumo, and others. But despite various applications, Ophthalmology is still the dominating field of biomedical OCT due to the precision of OCT that fits well the near-optical quality of many ophthalmological structures.
However, the high cost of equipment may strongly hinder the growth of the market.
Intended Audience
  • Medical Devices Companies
  • Hospitals & Clinics
  • Diagnostic Centers
  • Research and Development (R&D) Companies
  • Government Research Institute
  • Academic Institutes and Universities
Optical Coherence Tomography Market Segmentation Analysis
The global optical coherence tomography market is segmented on the basis of technology, application, and type of devices.
On the basis of the technology, the market is classified into spectral-domain OCT (SD-OCT), swept-source OCT, and others.
On the basis of the application, the market is segmented into cardiology, ophthalmology, dermatology, oncology, others.
On the basis of the type of devices, the market is segmented into handheld OCT devices, tabletop OCT devices, catheter-based OCT devices, and others.
Key Players
Some of key the players in the optical coherence tomography market are Carl Zeiss AG, Alcon, Abbott Laboratories, Terumo Corporation, KONINKLIJKE PHILIPS N.V, B. Braun Melsungen AG, Boston Scientific Corporation, Topcon Corporation, NIDEK Co., Ltd, Novacam Technologies Inc, OPTOPOL Technology S.A, Heidelberg Engineering GmbH, Optovue, Michelson Diagnostics, Thorlabs Inc., Agfa Healthcare, Imalux Corporation, and others.
Key Findings
  • The global optical coherence tomography market is expected to reach USD 1483.49 million by 2023 at a CAGR of 8.9%.
  • On the basis of the technology, Spectral-domain OCT (SD-OCT) is expected to command the largest market share of 60.1% over the review period, and Swept-source OCT is expected to grow at the fastest CAGR of 9.1% during the forecast period 2017-2023
  • On the basis of the Application, ophthalmology segment is expected to command the largest market share of 53.6% over the review period, and Dermatology is expected to grow at the fastest CAGR of 9.3% during the forecast period 2017-2023
  • The Americas hold the largest share of the global optical coherence tomography market and is expected to reach USD 558.34 million by 2023
  • Asia Pacific is the fastest growing market, which is expected to grow at a CAGR of 9.4% over the 2017-2023
Optical Coherence Tomography Market Regional Analysis
The Americas dominate the optical coherence tomography market owing to the increasing prevalence of prevalence of diabetic retinopathy, and other eye diseases, and the presence of the leading players in the region. According to the 2017 data suggested by Genentech, Inc., around 200,000 new cases of wet AMD are diagnosed in the United States each year. It is also reported that Diabetic retinopathy also impacts around 7.7 million Americans, and the number is expected to escalate to 11.3 million by 2030. Due to increasing acceptance of OCT systems multitude of products have been introduced by leading players, such as ARGOS by Santec, SPECTRALIS by Heidelberg, and others.  In November 2016, Carl Zeiss received FDA approval for PLEX Elite 9000, and commercially available in the United States.
Europe holds the second position in the optical coherence tomography market. The financial support provided by the government and private bodies for research & development is propelling the growth of the optical coherence tomography market in the European region. The prevalence of diabetic retinopathy and other eye diseases is also found to be very prevalent in the European region. As per the 2017 statistics suggested by European Society of Retina Specialists (EURETINA), it is found that age-related macular degeneration (AMD) currently affects nearly 34 million people in the European Union, and around 22 million people in the five most populous countries of Europe alone, i.e., Germany, the United Kingdom (UK), France, Italy and Spain.
Asia Pacific region is projected to be the fastest growing region during the forecast period. Rapid advancement in technology and rising participation of market players drive the growth of this market in Asia Pacific region. For instance, the first swept-source OCT was launched by Topcon in 2012, i.e., the DRI OCT Atlantis with 100,000 A-scans/s at the 1050-nm central wavelength. The system is approved in Europe (CE mark), but not approved for use in the U.S.
The Middle East and Africa hold the least share of the optical coherence tomography market owing to the presence of poor and slow developing countries, especially, in the African region.
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DNA Sequencing market growth and regional forecast 2019 - 2025

Market Scenario
The global DNA sequencing market is expected to grow significantly over the forecast period. It is estimated that the DNA sequencing market is expected to register a CAGR of ~ 17.64 % during the forecast period from 2018 to 2023.
The DNA sequencing method is used to determine the order of the nucleotide bases adenine, guanine, cytosine, and thymine in a molecule of DNA. The DNA sequencing market is driven by factors such as growing requirement of breeders for animals and plant production, development in technology, increasing research and development, growing prevalence of cancer, and growth in liquid biopsy applications. New market players get attracted towards the global DNA sequencing market, as a lot of research is taking place in DNA sequencing market. The increasing prevalence of cancer is boosting the DNA sequencing market globally. In addition, increasing use of genome mapping programs globally and R&D investments boost the market growth.  
However, accuracy and standardization concern and ethical and legal limitations associated with DNA Sequencing Market may hinder the market growth.
DNA Sequencing Market Key players
Key players in the global DNA Sequencing Market are Perkin Elmer, Roche Holdings AG, Siemens AG, Illumina, Agilent Technologies Inc., Genia Corporation, Oxford Nanopore technologies, Koninklijke Philips N.V., Pacific Biosciences, Johnson & Johnson, Deep Genomics, Inc., Life Technologies, Illumina, Eppendorf, Tecan, Thermo Scientific, Hamilton Thorne Biosciences, General Electric Company, Siemens Healthineers GmbH, Myriad Genetics, Bayer Corporation, Beckman Coulter, and others.
DNA Sequencing Market Segmentation
The global DNA sequencing market has been segmented on basis of type, product, technology, application, and end-users. On the basis of type, the DNA Sequencing Market is segmented into instruments and consumables services and workflow products. Based on products, the DNA Sequencing Market is segmented into sequencing services and sequencing instruments and consumables. Sequencing instruments and consumables are further sub-segmented into two types, namely, sequencing instruments and consumables by product type and by platform type. Sequencing instruments and consumables, by product type, are further sub-segmented into consumables and instruments, whereas sequencing instruments and consumables, by platform type, are further sub-segmented into NGS, sanger, bioinformatics, sample prep kits, and reagents. On the basis of technology, the DNA Sequencing Market is further segmented into semiconductor sequencing, pyrosequencing, sequencing by synthesis, single-molecule real-time sequencing (SMRT), sequencing by ligation (SBL), and other technologies. On the basis of application, the DNA Sequencing Market is further segmented into diagnostics, agriculture and animal research, biomarker discovery, personalized medicine, drug discovery, and other applications. Based on end-user, the DNA Sequencing Market is segmented into research centers and government institutes and academia, biotechnology and pharmaceutical companies, clinics and hospitals, and other end-users.
DNA Sequencing Market Regional Summary
The DNA Sequencing Market has been segmented, by region, into the Americas, Europe, Asia-Pacific, and the Middle East and Africa. The DNA sequencing market in the Americas has further been segmented into North America and South America, with the North American market divided into the US and Canada. The European DNA sequencing market has been segmented into Western Europe and Eastern Europe. Western Europe has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe. The DNA sequencing market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific. The DNA sequencing market in the Middle East and Africa has been segmented into the Middle East and Africa.
On the basis of region, the DNA Sequencing Market is segmented into North America, Europe, Asia-Pacific, and the Middle East and Africa. The North American market is anticipated to dominate the DNA sequencing market due to the rising prevalence of cancer among the geriatric population, developed innovation ecology, large buying power, and the presence of major players.
Europe is anticipated to drive the growth of the DNA Sequencing Market in the upcoming years due to increasing incidences of an aging population suffering from cancer, sedentary lifestyle, and an efficient reimbursement scenario.
Asia-Pacific is projected to register a robust growth in the coming years due to large patient population and growing healthcare infrastructure and expenditure.
The Middle East and Africa is expected to account for the lowest market share in the global DNA Sequencing Market due to the lack of advanced technology and poor medical facilities in developing economies in this region.
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Global 4D Printing in Healthcare market 2020 trends and competitive landscape outlook -2025

Market Overview
Global 4D Printing in Healthcare Market is expected to register a CAGR of 29.4% during the forecast period from 2019 to 2025 and expected to reach USD 30.4 Million by 2025.
In the past decade, there has been increasing use of 3D printing in the field of healthcare. The introduction of 4D printing and its shape-changing material property in the field of dentistry, implants, and prosthetics, among others will further enhance the 3D products used for these applications. The shape-changing property of the material used for 4D printing has been one of the major factors influencing the growth of the market.
Moreover, factors such as increasing research and development, rising investment by chemical companies. These chemical companies are keen on grabbing the opportunity for the development of smart materials in 4D printing, which in turn is directly enhancing the growth of the market.
Factors such as stringent regulatory policies for the approval of 4D printing medical devices market and limited skilled professionals have been major challenges for 4D printing in the healthcare market.  
Market Drivers
  • Increasing application of 4D printing in healthcare verticals such as dentistry, implants, and prosthetics.
    • The dental industry is one of the major applications of 4D printing. Clear aligners have been the most manufactured products via 3D printing in the dental industry.
    • Align technology, the leader in global clear aligners market, accounts for about 80% of the market. The company uses 3D Systems to produce over 1.6 million custom aligners per week.
    • Clear aligners can further be enhanced using 4D printing, as these products require shape altering properties according to the changing structure of the teeth on a weekly basis.
    • 4D printers are also used to manufacture various dental implants, including dental implants, dentures, crowns, & bridges, among others.
    • Increasing prevalence of dental diseases is further influencing the growth of the market. According to the MRFR research study in 2018, it was estimated that oral diseases affected more than 3.7 billion individuals that are around half of the world’s population.
  • Rising research and development
    • A research team from the US in March 2019, invented a new bio-ink that allows to print catalytically active live cells into several self-sustaining 3D geometries. These properties include tunable cell densities, fine filament thickness, and high catalytic productivity.
  • Growing investment by chemical companies
    • Various companies such as BASF Venture Capital GmbH and Evonik Venture Capital have invested in Chinese 3D printing companies
Market Challenges
  • Stringent regulatory policies for the approval of 4D printing medical devices
  • Limited skilled professionals
Segmentation
By Component
  • Software & Services: Software and services accounted for the major market share in 2018. 3D printers have already been installed in numerous healthcare facilities across the globe. However, these machines would require updated software and also various services for the manufacturing of 4D products.
  • Smart Material: Smart Material segment is expected to grow at the fastest growth rate due to continuous advancements for the materials in 4D printing. Investment by chemical companies for the development of smart material is further influencing the market growth.
By Technology
  • Fused Deposition Modeling: Accounted for the largest market share due to its wide choice of raw materials and cost-effective process
  • Direct Inkjet Cure: Expected to grow at the fastest growth rate majorly due to its dimensional accuracy, multi-material, and full-color printing properties
By Application
  • Dental: accounted for the largest market share owing to the use of 4D printing for manufacturing of wide dental products including clear aligners, implants, and dentures among others
  • Prosthetics: Expected to grow at the fastest growth rate due to increasing number of prosthetic procedures, accidental injuries, and sports injuries among others
By End-User
  • Hospitals & Surgical Centers: Accounted for the leading market share owing to the increasing number of hospital & surgical centers. According to a study published by the American Hospital Association, there were 5,534 registered hospitals in the US in 2017.
  • Dental Clinics & Laboratories (Offices): Use of 4D printing in dental clinics & laboratories, brings less complexity to existing procedures. Dental laboratories use 4D printing technologies that allow them to increase competitiveness and production, thus driving the growth of this segment.
By Region
  • Americas: The Americas spearheaded the market in 2018 and is likely to continue to command during the assessment period. This is attributed to the existence of a large number of medical device companies, increasing research and development, and the presence of a large number of noticeable players engaged in manufacturing of 4D printing devices and software
  • Europe: Reported for the second-largest share owing to increasing utilization of 3D & 4D printing in the field of healthcare. According to a study conducted in 2018, it was found that 65% of healthcare providers are implementing new printing technologies for medical products using custom made materials
  • Asia-Pacific: The highest growth rate is attributed to the growing investment by government bodies and private & public companies. For instance, in November 2018, BASF Venture Capital GmbH invested in Chinese 3D printing company Prismlab.
Key Development
  • In January 2019, Dentsply Sirona and Carbon announced a strategic collaboration to revolutionize digital denture materials. This strategic collaboration was announced to deliver denture materials for carbon digital 3D printing production solutions.
Key Players
  • Stratasys Ltd (US)
  • 3D Systems, Inc (US)
  • EnvisionTEC (Germany)
  • Poietis
  • (France) 
  • Organovo Holdings Inc. (US)
  • Materialise NV (Belgium)
  • Dassault Systèmes (France) 

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Meningococcal Vaccines market growth and regional forecast 2019 - 2025

Market Forecast
Meningococcal Vaccines Market has a demand for USD 172 Million doses in 2019. Further, the global estimated supply in 2019 is expected to be 203 Million doses.
Market Synopsis
Meningococcal meningitis is a bacterial infection caused by Neisseria meningitides. Disease incidence is high in West and Central Africa, where historically, serogroup A has been the most important cause of disease. More recently, meningitis outbreaks have gradually been associated with serogroup C, and to a lesser extent, serogroup W.
The meningococcal vaccines market is complex and diverse, with regional variations in serogroup distribution with substantial use outside routine immunization. The vaccine has approximately 29 marketed products targeting various combinations of the six serogroups (A, B, C, W, X, Y).
Market Influencer
Without an increase in production, the existing supply of conjugate MenACWY will be inadequate to meet the demand generated by the rising incidence of serogroups C and W, and the low availability of polysaccharide vaccines. Further, several multivalent, conjugate vaccines by Chinese and Indian manufacturers are in the pipeline, and, if prequalified they will be registered for use in many geographies. Moreover, if they are made available at acceptable prices it could increase global demand in Meningococcal Vaccines Market.
Market Drivers
  • Rise in prevalence of the meningococcal disease
    • According to a document published by the U.S. Department of Health & Human Services, in 2017, there were approximately 350 cases of meningococcal disease reported. The disease has an incidence rate of 0.11 cases per 100,000 people in the United States. Any population group can be affected by the disease, with maximum prevalence in children younger than one-year-old and a second peak in adolescence. Adolescents and young adults, ranging from 16 to 23 years old, have the highest rates of meningococcal disease.
    • Further, increasing incidence of meningococcal disease in West and Central Africa regions is expected to drive the demand in the African region
  • Booming mortality of the meningococcal disease is leading to increasing demand for the vaccines
    • Approximately 10 to 15 in 100 people affected with meningococcal disease will face mortality. Further, up to 1 in 5 survivors will have long-term disabilities, such as loss of limb, deafness, and damage to the nervous system brain among others
  • Escalating positive results with the vaccines to boost the demand in the market
  • Growing research and development activities by prominent players in the industry
Market Restraints
  • Withdrawn production of polysaccharide vaccines has resulted in reduced country access, particularly for MICs in various regions. For example, Sanofi Pasteur, manufacturer of Menomune, declared in 2017 that the company is discontinuing the production of the vaccine. With the production of Menomune at hold, there were no polysaccharide vaccines approved for use in the United States

Meningococcal Vaccines Market Segmentation

By treatment, the market is segmented into Meningococcal Conjugate Vaccine, Polysaccharide, Subcapsular Vaccine.
Meningococcal A conjugate vaccine is significantly used in mass campaigns across affected regions like Africa. Since 2010, the vaccine has significantly decreased meningococcal disease incidence in the region. However, the demand for meningococcal A conjugate in the country remains uncertain given that national immunization program adoptions are based on the timing of Gavi funding decisions, the country’s readiness, and competing for vaccine introduction priorities.
In the polysaccharide segment, products such as MenACWY vaccines are in high demand. MenACWY vaccine is the most desirable combination, given its broader serotype coverage. MenACWY specifically has nine products that are available across polysaccharide and conjugate product segments, but conjugate products are suggested for use in routine immunization activities.
Moreover, the demand and supply of Subcap MenB vaccines is restricted to HICs and influenced by their acceptance into NIPs. Improved uptake of MenB vaccines is expected in the coming years but will likely be moderate and limited to high-income markets given the high price and competing interest of introducing MenACWY conjugate.
By end-user, the market is segmented into Hospital & Clinical, Research Laboratories, and Academic Institutes
Hospitals and clinics control the global market for meningococcal vaccines. The high growth of hospitals and clinics segment is attributed to the increasing application of vaccines in these healthcare facilities in conjunction with the growing prevalence and incidence of the meningococcal disease.
Moreover, research laboratories and academic institutes take up the second-largest share due to the boost in research and development in the market.
By region, the market is segmented into the Americas, Europe, Asia-Pacific, and the Middle East & Africa.
In the global market, China is expected to have the largest market share, which accounts for approximately 35% of the global demand. This is primarily due to polysaccharide products, which currently comprise 84% of China’s demand. Chinese suppliers presently focus only on meeting the demand of the domestic market, but some of the manufacturers have indicated interest in the global market as well. The dynamic product pipeline with several multivalent conjugate products in development may trigger changes in the future supply mix of the Chinese market. Moreover, in China, non-routine use (excluding campaigns) accounts for an estimated 9 million doses in 2019, which may help to sustain the huge market share in the forecast period.
UNICEF foresees all 26 African countries in the meningitis belt, which have completed mass campaigns in 2016. In 2015, seven countries in the region were introduced with meningococcal A conjugate vaccine through their mass campaigns and targeted a population of 233 million. Further, during 2016-2018, UNICEF introduced meningococcal A conjugate vaccine in 26 countries. Ghana was the first country to be introduced with the vaccine into its RI schedule in 2016. Also, four other countries including Mali, Niger, Nigeria, and Sudan introduced the vaccine into RI programs in 2016.
Key Developments in the Global Meningococcal Vaccines Market
  • In 2018, Pfizer granted FDA Breakthrough Therapy designation for Trumenba (Meningococcal Group B Vaccine). This vaccine plays a major role in the prevention of invasive meningococcal B disease in children aged 1 to 9 years
  • In 2018, GSK’s meningitis B vaccine Bexsero received Breakthrough Therapy designation from the US FDA for prevention of Invasive Meningococcal Disease for children 2-10 years of age
  • In 2015, Novartis Bexsero vaccine was approved by the FDA for the prevention of meningitis B. This vaccine is used as active immunization to prevent invasive meningococcal disease caused by serogroup B
Key Players
  • Baxter international
  • Pfizer Inc.
  • Sanofi S.A.
  • Novartis Pharmaceuticals Inc.
  • JN-International Medical Corporation
  • Serum Institute of India Ltd.
  • GlaxoSmithKline
  • BIO-MED
  • Others
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